Dog DNA Tests

Dog DNA Tests_The owner is isolated and the pet needs swab test!

A few days ago, a patient in the USA, was diagnosed with a COVID-19 infection. Due to the quarantine, no one at home is taking care of the pet dog. So she turned the dog over to the US Animal Protection Service.

The site is responsible for monitoring animal welfare and controlling animal and plant infectious diseases, such as foot-and-mouth disease, bird flu and other animal diseases.

The staff suddenly wondered if the dog also carried the new coronavirus-19. Therefore, the staff took swabs (secretions and feces) samples from the dog’s mouth, nose and anus for the new coronavirus nucleic acid test.

The new test results were unexpected: the oral and nasal swabs of the new coronavirus-19 were weakly positive in the swab test, and the anal swab test was negative.

However, the symptoms of COVID-19, such as fever and cough, look very lively and healthy.

The transmission of COVID-19 to pets has been the focus of discussion in the scientific community.

Currently, the Society’s Animal Residence has only tested this dog. Not sure if other animals have the same problem.

Subsequently, staff stepped up protective measures for the animal shelter and disinfected its facilities, walls and floors. Out of an abundance of caution, staff also isolate the dogs and observe them closely.

The person in charge of the animal protection station said that the dogs will be re-examined after that.

Although the pet dog had no symptoms of Covid-19 infection, the discovery of suspicious evidence of Covid-19 infection for the first time really took the world by surprise.

The swab test for COVID-19 was weakly positive, with both false positives and positives.

If the dog’s new coronary pneumonia swab test is finally positive, there are two possibilities: one possibility is that the dog is also infected with new coronary pneumonia; the other possibility is that the dog brought the virus into the mouth or Nasal, i.e. mechanical carry.

A dog’s mouth, nose and ground compared to a human. Surfaces with closer contact and smell habits are more likely to inhale some pathogens, including COVID-19 that may be present in the environment.

It is worth noting that the current medical institutions pay more attention to the diagnosis and treatment of infected patients; the CDC pays more attention to the source of the new coronavirus-19 infection and adopts various prevention and control measures. Few institutions test animals that are closely related to people, such as pet dogs, domestic cats, livestock, and even domesticated birds.

Whether these closely related animals carry the new coronavirus disease as a vector of infection or transmission; or whether dogs can be infected with the new coronavirus is unclear.

Dogs themselves can also be infected with coronaviruses, but the common coronaviruses that dogs contract cannot infect humans;

why?

The cat is being made a swab test

The cat is being made a swab test

Generally speaking, a virus needs to enter an animal or human cell in order to infect, replicate, and cause disease.

First, the virus must recognize receptors on the surface of the cell it wants to invade.

For example, SARS-CoV-2 needs to bind to a receptor called angiotensin-converting enzyme 2 (ACE2) to infect humans and cause disease, which is the equivalent of a key to a lock.

The virus then binds to a receptor expressed by the cell, the virus integrates into the cell, and infects the cell.

The ultimate determinant is its genetic material and genes (the material basis is DNA).

Obviously, the DNA of animals and humans is different, and the proteins expressed on the cell membrane are also different. Sometimes it looks the same. As long as

several amino acids are related, the profile of the protein is different and the virus cannot bind to it.

However, this is not absolute, as the virus is constantly mutating and adapting to the environment.

If the new coronary pneumonia can be directly transmitted across species, it can indicate that this virus infection is a zoonotic disease, which is obviously very bad.

A warm reminder from Dr Lee:

We found weak nucleic acid positive for New Coronavirus disease in pet dogs.

This message tells us:

1. In addition to guarding against infection by infected persons, it is also necessary to avoid close contact with active animals, including pets living together for a long time;
2. If you accidentally touch these animals, you must wash your hands afterwards;
3. Wear a mask and do a good job of protection before touching animals as a last resort;
4. During the epidemic, we suggest taking good care of pets and do not take pets for a walk outdoors.

Nylon Flocked Swabs

Nylon Flocked Swabs

During an outbreak, everyone should be familiar with sampling swabs. When doing nucleic acid, touching the nose and throat is directly touching the sampling site of human organs, that is, directly touching our human organs. Therefore, the material of the sampling head will affect our comfort and is closely related to the subsequent detection.

Sampling swabs should be polyester, nylon and other non-cotton, non-calcium alginate swabs, and the handle should be non-wood. The breakpoint is located about 3cm from the top of the swab head, which is easy to break.

NASAL FLOCKED SWAB

NASAL FLOCKED SWAB

Moreover, the experimental analysis shows that the extraction efficiency of nylon flocked swabs is the highest. In contrast, the recovery efficiency of nylon flocking swabs is also higher than that of other material swabs.

Nylon fibre flocking technology. The front end is coated with vertically fixed nylon short fibers, so that the entire sampling area of ​​the sampling swab has no absorption holes, and the sampling sample will not be scattered in the fibers, which is conducive to faster and more efficient sampling!

Compared with traditional winding swabs, nylon flocking swabs collect and release 3 times the number of samples, do not damage cell samples, ensure the survival rate of cell samples, do not leave fatty acids, do not affect the test and detection results, not to mention Said to cause harm to the human body.

What materials cannot be used for sampling swabs?

As we all know, the materials of medical swabs have always attracted much attention. After all, medical swabs come into direct contact with the skin. People who touch the skin can first touch alcohol for disinfection, that’s fine, but what about those who have direct contact with organs? For example, the throat swab we are most familiar with during the epidemic.

The throat swab is in direct contact with the sampling site, and the material of the sampling head is closely related to subsequent testing. The sampling swab head should be made of nylon flocked swabs or rayon, and calcium alginate sponges or wooden stick swabs (including bamboo sticks) should not be used.

Cotton products should not be used for the swab head, because the cotton fiber has strong adsorption to protein and is not easy to clean into the subsequent storage solution; wooden.

What are the types of swab tests?

There are two different types of COVID tests – Swab tests and antibody tests.

1. Swab tests can show if you have an active coronavirus infection and should take steps to isolate or isolate yourself from others. There are currently two types of diagnostic tests – molecular (RT-PCR) tests that detect the genetic material of the virus, and antigenic tests that detect specific proteins on the surface of the virus. Samples are usually collected with a nasal or throat swab, or saliva spits into a test tube.

2. Antibody tests look for antibodies that the immune system produces in response to a threat, such as a specific virus. Antibodies can help fight infection. Antibodies can take days or weeks to develop after infection and may remain in the blood for several weeks after recovery.

Therefore, antibody tests should not be used to diagnose active coronavirus infection.

Right now, researchers don’t know whether the presence of antibodies means you’ll be immune to the coronavirus in the future. While there is a lot of uncertainty surrounding this new virus, the widespread availability of antibody testing and clinical follow-up over time also has the potential to provide the medical community with more information about whether and how long a person has recovered from the virus of people have a reduced risk of infection if they are re-exposed to the virus. Learn more about antibody testing.

Flu Swab Test

Flu Swab Test

Influenza, commonly known as influenza, is an acute respiratory disease caused by influenza A, B, and C viruses, and belongs to Class C infectious diseases. Influenza is an illness that spreads relatively easily from person to person and can infect large numbers of people. While most people recover quickly from the flu, some, such as older adults, are at risk of serious illness and even death.

Flu Swab Test

Influenza viruses come in many different forms. A flu swab is a method of taking a sample from a person. Medical staff check patients for flu. If so, what kind of flu virus can be spread by inhalation through the nose and throat of an infected person.
When the flu virus infects a person, it spreads through the respiratory tract. The nose and throat are where the virus lives and grows, causing symptoms such as a runny nose, sore throat and cough. These places are also the easiest places for doctors to obtain samples. As a result, doctors can often use flu swabs to determine whether a patient has the flu, which often spreads quickly in a population.
Due to public health, some government medical agencies may wish to track the spread of the disease. Since influenza viruses also mutate rapidly, new influenza viruses are produced regularly. The type of flu a person has can also be important information for the public health system.
Finally, a doctor may need to determine whether a person has the flu so an appropriate treatment plan can be instituted. There are several ways a doctor can use a swab to determine if a patient has the flu virus. An area of ​​medical professionals, usually to test for microbes. (Nasal swab for flu)

How to do Nasal Swabbing for COVID

A sampler is doing a swab test for a woman

How to Swab for the Flu?

They usually have a long swab stick with a soft swab tip at the end, made of cotton material, polyester, polyester or rayon tip, nylon flocked swabs. is sterile, so the test only analyzes the microbes in the sampled area. During the flu swab procedure, doctors usually insert the end of the swab into the patient’s nose and spin the flu swab to collect as much mucus as possible.
A doctor can take a sample by inserting a swab into the top of the throat through the nose. If the virus grows heavily in the area, the flu can cause dizziness.
Doctors have several different ways to test a cotton swab for the flu virus. The test that takes a few days to a week to complete is a viral culture, in which viral particles are grown in human cells.
Rapid tests include tests that analyze the sample for the presence of genetic material or antigens from the flu virus. An antigen is a special molecule in a virus. Some commercial tests contain antibodies, and the presence of antigens can be recognized by their linkage to the antigens.
These tests are less than an hour, but may not be as accurate as viral cultures. A runny nose and sore throat can be symptoms of the flu.

How do I know if I have the flu?

If you have a fever, cough, sore throat, runny or stuffy nose, body aches, headache, cold and/or fatigue, your respiratory illness may be the flu (flu). Some people may experience vomiting and diarrhea, although this is more common in children. People can get the flu without having a fever. Influenza viruses usually cause the most illness during the colder months of the year. However, the flu can also occur outside of a typical flu season. In addition, other viruses can cause flu-like respiratory illnesses. Therefore, it is not possible to tell if you have the flu based on symptoms alone. If your doctor needs to determine if you have the flu, you can do laboratory tests.

Can I get the flu and COVID-19 at the same time?

Yes. Co-infection with influenza and other respiratory illnesses, including COVID-19, is possible. Health experts are still studying how common the condition is.

The flu is similar to some of the symptoms of COVID-19, so it’s hard to tell them apart based on symptoms alone. The swab diagnostic test helps determine if you have the flu, COVID-19 or other respiratory infections.