Flocked Swabs and Custom Swab Manufacturing

COVID-19: Main Symptoms

The three main symptoms of “new crown”: are fatigue, brain fog and muscle pain, the specific manifestations vary from person to person. Other more common persistent symptoms include shortness of breath, chills, body aches, headache, joint pain, chest pain, cough, and persistent loss of taste or smell.

Flocked Swabs and Custom Swab Manufacturing

ISO13485 Quality Management System Disposable Sampling Swab Production Quality Standard Sterile Swab.

 Forgetfulness, anxiety: “I feel useless”

Many people with long-term symptoms report cognitive impairment or memory loss that affects their ability to make everyday decisions, speak, follow directions and drive, and impair their quality of life.

Xiao Liu (pseudonym) works in British media. Three years ago, he suffered from depression. He largely recovered before contracting Covid-19 in November 2021 and has stopped taking antidepressants. But after she contracted Covid-19, the depression returned. The doctor assessed and judged that one of the symptoms of the new crown-brain fog persisted.

“After I got the new crown, I felt that I was ‘brainless’, I didn’t want to do anything, and I was extremely anxious.”

It starts with cold-like symptoms, headache, cough, fever, and loss of taste and smell. There are also chest tightness, shortness of breath, fatigue, insomnia, loss of appetite, forgetfulness, inability to concentrate, unresponsiveness, anxiety, etc.

“The overall condition is not good, and the weight has lost four kilograms”

After Xiao Liu fell ill, the children became sensible. I get up every morning looking for a school uniform to wear, and my 11-year-old will scramble eggs, eat breakfast, and go to school alone. My brother was hungry at night, so he cooked instant noodles and ate them together.

Flocked swab

Flocked swab

Xiao Liu remembers coughing for three weeks, being bedridden for a month, and then taking a long sick leave of more than three months.

“I couldn’t get out of bed to cook at all. The children ate takeaways every day, and my mouth ulcers had developed for a long time. Fortunately, some friends helped us and often brought us home-cooked food. At that time, the volunteers in the community even gave me anti-inflammatory drugs. Depression. Come to my house and make sure I take it on time. My family doctor advised me to call my psychiatrist again.”

“The biggest motivator for me was the several home visits from the social worker in charge of child welfare. The kind help made me extremely anxious and insomniac, and I felt like an incompetent mother who couldn’t do even the most basic things to take care of her children.” Covid has cost me! It’s unacceptable to me.”

“Regular doctor consultations and cordial greetings from unit leaders also made me feel like I was a burden. I didn’t want to be sick all the time. Everyday burnout and bedridden made me feel like I was useless.” “

For a long time, Xiao Liu felt that he had Alzheimer’s disease. Can’t remember anything, looking for something every day. It takes a few repetitions to understand what the doctor says. Sometimes after calling in the morning to confirm, call in the afternoon to ask.

“Sometimes I don’t know if I have taken medicine or not. Once I enter the kitchen, I forget what I am doing. I look at the pills with a water glass and ask myself if I just took the medicine or not?”

Because of the confusion caused by many small things, Xiao Liu deeply doubts his ability to do things. She feels that she must first learn to forgive herself and accept herself who is often tired and forgetful now.

Xiao Liu said that now he wants to make himself happier and more optimistic by doing one small thing every day. Doctors want to taper off antidepressants over a year.

Fatigue: “Three hours of sleep when I get back from the store”

Severe fatigue is by far the most common symptom of COVID-19. Other symptoms include muscle pain, hearing and vision problems, headaches, loss of taste and smell, damage to the heart, lungs, kidneys, and intestines, diarrhea, and mental health problems, including depression, anxiety and distraction, and stupor.

Before being diagnosed with “coronavirus”, she had been suffering from persistent fatigue, fever, and loss of smell and taste for months, for which she consulted several doctors of different specialties.

At first, my temperature rose slightly, I felt dizzy, and then my throat started to hurt. A day later, my fever reached 38.5°C. 

Later, I went for a checkup and received treatment. 

After three weeks of conventional viral infection treatment, tachycardia was found, while fatigue symptoms did not decrease.

Frequent blood tests, blood pressure measurements, and lung monitoring are performed. After taking antibiotics and vitamins for three weeks, the treatment failed, and he underwent ENT, pulmonology, cardiology, virology, rheumatology and immunology tests. Found chronic sinusitis, and heart adhesion, but not sure if it is caused by the new crown, it was still there before.

After a month, blood cell counts stabilized, but mental and physical fatigue and fever persisted.

For seven months, I was unable to concentrate, disoriented, felt hot, shivering, tired, didn’t know when it was going to pass, and felt scared every day.

At the doctor’s advice, make a “resurrection” plan, start walking, but take breaks from time to time, sleep at least three hours after going to the store or spend an hour in front of the computer.

The child is doing nucleic acid nasopharyngeal testing

The child is doing nucleic acid nasopharyngeal testing

Feeling changes, headaches, fatigue and brain fog are just a few of the symptoms of ‘coronavirus’

 Cognitive Function and Brain Fog: “IQ Decreases…”

“I’m not back to normal, from a cognitive standpoint, I’m not back to where I was before the coronavirus, in terms of focus, agility, flexibility… a year and a half later, I feel like I’ve only lost 30-40 %”. she says. % has been restored. I’m not the same as before, my IQ has dropped. “

“After a year and a half, after a lot of hard work, a lot of self-discipline, and all things considered, my condition has improved. I have anxiety (cognition) and I won’t fully recover, but I’m slowly accepting the possibility.”

Mrsa Nasal Swab

Mrsa Nasal Swab

The way to prevent MRSA transmission in hospitals is to screen high-risk patients admitted to the hospital for MRSA, and then isolate those who screen positive.

Methicillin-resistant Staphylococcus aureus (MRSA) is increasingly rampant, and its infection spreads almost all over the world. Together with AIDS and hepatitis B, it has become the three most difficult infectious diseases in the world. How to prevent and controlling MRSA has become a problem that cannot be ignored.

The long-term treatment of MRSA infection, in addition to the direct economic burden on patients, will also generate some indirect costs, such as isolation, disinfection and so on. Strict detection and control measures should be proposed in response to the prevalence of MRSA. MRSA screening is an important part of this.

MRSA is one of the major pathogens of nosocomial infections. The epidemiology and microbiology of MRSA vary around the world and provide an important basis for developing strategies to prevent and control its infection.

MRSA can be classified into hospital-associated, community-acquired, community-associated, and livestock-associated. Community-associated and livestock-associated MRSA are relatively recent, and this article focuses on hospital-associated MRSA.

At present, the optimal screening strategy and expansion scope of MRSA colonized or infected patients are still controversial.

Which patients should be screened for MRSA?

Flu Test Throat Swab China Factory And Manufacturers

A throat-flocked swab for influenza is more accurate. Throat swab testing for influenza is very fast, economical, and simple.

Proponents of universal screening claim that this strategy significantly increases the detection rate of MRSA carriers. Others argue that universal screening protocols are too expensive and that patients with risk factors for MRSA colonization should be tested.

Universal screening may make it easier to identify MRSA carriers and those at high risk of infection.

The Scottish Health Technology Assessment study showed that universal screening as part of a programme to control MRSA is potentially effective and cost-effective.

The MRSA screening clinical risk assessment questionnaire in this study included the following questions:

(1) Does the patient have a history of MRSA colonization or infection?

(2) Where has the patient been other than his own home?

(3) Did the patient have wounds or ulcers, and whether there were prostheses or medical implants in the body before admission?

But then a large prospective study including nearly 70,000 patients showed that screening all patients admitted to “high-risk” specialties (intensive care, orthopedics, nephrology, vascular surgery, cardiothoracic surgery), based on the above Targeted screening of other hospital admissions for the three questions, combined with clinical risk assessment, can achieve similar detection rates and significantly reduce costs.

 Although high in-hospital prevalence is associated with MRSA, key risk factors may vary by country.

Risk factors for MRSA colonization in adults in emergency care settings:

(1) Hospitalized in the past 24 months.

(2)  a long-term care facility or rehabilitation facility within the past 18 months.

(3) an intensive care unit in the past 5 years.

(4) In-hospital transfer.

(5) Received surgical intervention within the past 60 months.

(6) Indwelling urinary catheter.

(7) Antibiotics used in the past 12 months.

(8) There is skin damage.

(9) History of MRSA colonization in the past.

(10) Chronic health comorbidity assessment grade C or D (patient severely restricted in activity due to chronic disease or bedridden).

(11) The presence of terminal disease.

(12) Male.

When should MRSA screening begin?

Eligibility for screening of all other admitted patients should be based on local policy and screening as early as possible. Ensure that appropriate interventions are applied as soon as possible to reduce the risk of infection in the patient and avoid infecting others.

How to screen for MRSA?

Nasal Swab Test

A nasopharyngeal culture is a test that examines a sample of secretions from the uppermost part of the throat, behind the nose,

Standard screening swabs should include (a) nasal and perineal swabs or (b) nasal and pharyngeal swabs. 

(1) The optimal protocol and screening range for MRSA screening are still controversial.

(2) Clinicians must understand and implement local MRSA colonization patient screening and management policies.

(3) Standard screening swabs should include (a) nasal and perineal swabs or (b) nasal and pharyngeal swabs as a minimum screening to identify colonized or infected patients. For whom subsequent Manage to reduce the spread of MRSA, including close contact protection, decolonization, and isolation.

(4) Time boundaries should be provided for the acquisition of screening results so that effective interventions minimize the risk of infection and transmission to others.

To sum up, it is suggested that in relatively underdeveloped medical institutions, we may directly carry out decolonization interventions for high-risk groups, and perhaps do not need to do the screening. Because the cost of screening is indeed very high, many hospitals do not have rapid screening facilities. technology. Direct decolonization or direct isolation of high-risk groups may result in intervention for some uncolonized high-risk patients, but it may be more cost-effective than full screening.

 

Sterile Foam Tipped Applicator

Sterile Foam or Flocked Tipped Applicator

Sterile Foam or Flocked Tipped Applicator

The outbreak of the novel coronavirus pneumonia in 2020 on a global scale has brought significant losses to human society. Viral nucleic acid detection plays a key role in epidemic prevention and control.

As the first step in viral nucleic acid detection, specimen collection is an indispensable link.

The amount of virus collected and released by sampling swabs is directly related to the positive rate of nucleic acid detection. As the gold standard, nucleic acid detection plays an important role in virus detection, and the role of swabs as a sample collection tool should not be underestimated. Among them, throat swabs and nasal swabs are most commonly used, and anal swabs are also used as auxiliary tests.

During the epidemic, researchers from various countries analysed and found that the efficiency of flocking nasal swab sampling and the acquisition of virus samples were the best.

At the same time, in order to solve the problem of the shortage of nasal swabs.

Nasal swabs

Nasal swabs

The researchers proposed a combined sampling method of oropharyngeal and nasal swabs to achieve the same effect as nasal swabs.

As the main tool for sampling, swabs have important applications in the fields of forensics, clinical medicine, and environmental testing.

Swabs of different materials, such as rayon, foam, polyurethane, polyester, flocked nylon, etc., will have different structures and performance differences and have different collection effects for different specimens such as protein and nucleic acid, which will affect the detection.

The selection of appropriate swabs according to different sampling samples and testing indicators is very important for testing, and the proper use of swabs is also very important for sample collection and the safety of medical staff.

Flocked Swabs and Custom Swab Manufacturing

ISO13485 quality management system for producing disposable sampling swabs, quality standards, and sterile swabs.

Nylon flocking swabs–small nylon fibres to a moulded plastic rod.

This production process significantly increases the surface area of ​​the nylon swab, which is conducive to the adsorption of bacteria and easy release.

Oral Foam Swabs 104mm (with 22mm breakpoint)

Oral Foam Swabs 104mm (with 22mm breakpoint)

The sponge swab is soft in texture and has numerous tiny pores. It has strong adsorption to liquid, can collect more target analytes, increase the number of samples collected, and can release a large number of samples without defibrillation.

How to elute, etc., which will affect the test results. Many factors can affect the swab sampling results.

 

 

 

 

 

 

The cotton swab used to poke the throat or nose during the nucleic acid test of the new crown should be called an aseptic sampling swab, also called a pharyngeal swab. According to different sampling sites, including nasopharyngeal swabs and oropharyngeal swabs.

The swab is in direct contact with the nasopharynx or oropharynx to absorb the secretion sample, then put the head with the secretion into the culture solution, break the handle through the breakpoint, seal the lid and send it for testing.

Nasopharyngeal Sampling Procedure

Nasopharyngeal Sampling Procedure

In this process, the swab involves two links: sampling and elution (release the collected sample into the culture medium). The choice of different materials will affect the efficiency of sampling and release, and also affect the correctness of PCR detection. There are certain requirements for the material of the sampling swab.

PCR TEST

According to different materials, common swabs can be divided into medical cotton swabs, foam swabs and flocking swabs.

Several reports have shown that the sensitivity of medical cotton swabs in collecting respiratory samples is low, and natural fibres such as cotton have strong adsorption to proteins, which is not conducive to the subsequent release in the culture medium.

Generally, cotton swabs also have wooden handles, which may adsorb proteins during storage and interfere with virus detection. In addition, the wooden handle is too hard to break, and can also cause safety problems when sampling.

The US CDC recommends that the swab head material— synthetic fibres. The use of calcium alginate swabs or swabs with wooden shafts may inactivate certain viruses and reduce Accurate substances.

Flocked Sterile Swabs

Sterile Flocked Nasopharyngeal Swab: a 100% nylon flocked swab that provides exceptional absorption quality.

We produce flocked swabs, VTM kits, virus transport medium, and Specimen Collection Swab with multiple automatic production lines.

Including automatic VTM tube production line, OEM VTM Tube, Flocked Swab Production Line, etc.

We support custom production, OEM and so on, and develop products with customers.

Flocked Swabs For Sample Collection

Flocked Swabs For Sample Collection

The nucleic acid test (PCR TEST) uses a flocked swab instead of a cotton swab.

Flocking is a craft, not a material

   Flocking is not the fluff of any plant, but a very common fabric treatment process.

         Widely used in the textile industry, automobile manufacturing, printing industry, chemical industry and other fields.

   The flocking process means vertical fixing of some cut or milled short fibres to some kind of adhesive-coated surface. Short fibres are usually nylon, polyester, or other artificial fibers. The range of planting them is very wide, and surfaces such as cloth, plastic, wood, leather, paper, etc. can be flocked.

  Flocking only needs three things, 1, short fibers; 2, adhesive, 3, some kind of surface

   Flocking is very common in everyone’s life, just usually without realizing it. For example, flocking fabrics can be found on clothes, curtains, carpets, and furniture. Usually, those surfaces that are fluffy and comfortable to the touch are brought by the flocking process.

   In addition to the decorative effect, the flocking technology has also been tried by scientists to make graphene lithium battery anode sheets; make special lipophilic and hydrophobic materials to absorb marine oil spills, etc.

The principle of flocking

   At present, the most commonly used flocking method is electrostatic flocking. After the fluff enters the high-voltage electric field, it contacts the negative electrode and is negatively charged. 

   Don’t worry if some fibers fall to the side and don’t stick to the side. After they touch the positive electrode side, the negative charges on the surface are completely neutralized, and they will fall to the negative end due to the force of the electrostatic electric field. Repeat the above movement until they are all stuck.

Flocked swabs for nucleic acid testing

   The flocking swabs used for nucleic acid detection are mostly “planted” with nylon short fibers. The reason for choosing flocked nylon over cotton swabs is the functional need for sampling.

Flocked swab

Flocked swab

Any material design is purposeful, and flocked swabs for nucleic acid detection need to meet the following characteristics:

    ② After the swab is put into the preservation solution, it has to “let go” to release the biological sample, and it cannot hold the sample firmly for a second or divide it. ③ It cannot react with biological samples and destroy the samples.

   Because cotton itself has superior hydrophilicity and adsorption, once it comes into contact with the sample, it is like the characters in Qiongyao play. In contrast, nylon flocked swabs are like a scumbag “can take it and put it down.

   Therefore, the collection and release volume of nylon flocking swabs is much larger than that of traditional winding cotton swabs. Experimental studies have shown that the collection and release volume of flocking swabs can reach 95% of the samples, while cotton swabs are only about 20%.

  In fact, the ability of cotton swabs to grasp the sample is not bad, but after inserting the preservation solution, the flocked swab can quickly let go of the sample to be eluted, but the cotton swab will make the cells stuck in the fiber mass and cannot be separated.

 Otherwise, the nucleic acid will be degraded before the detection begins, and the correct result will definitely not be detected.

   Because of this, it is superfluous to worry that nylon is a synthetic fiber that is harmful to the human body. Flocked fibers have even been tried in regenerative medicine to help repair damaged bones and cartilage. By implanting the flocked fibrous scaffold, the properties of the extracellular matrix are modeled, allowing stem cells to adhere to it to proliferate and differentiate; and provide sufficient space for the newly synthesized matrix and capillaries to enter.

Sterile and Flocking Swabs

Sterile and Flocking Swabs

Product Usage:

CellMedical nylon flocked swabs: widely used in bacteriological sample processing, virological cell culture, DFA testing, rapid direct testing, enzyme immunoassay testing. Pory viruses such as influenza, swine flu, bird flu, hand, foot and mouth.

Sterile and Flocking Swabs

Sterile and Flocking Swabs

Sampling swab product features:

1. It has an extraordinary water absorption capacity, which can increase the number of samples collected on its surface from 20% of traditional sampling swabs to 60%.
2. It has a release rate of more than 90% of the collected samples, thus ensuring the high degree of results. Reliability
3. Different preservation solutions are selected for different specimen types
4. The plastic rod has a unique breakable design, which is convenient for specimen transportation
5. Ethylene oxide sterilization, irradiation sterilization, independent packaging

DNA flocking swabs are suitable for human and animal use, and have advantages over other DNA swabs in design. Its unique swab matrix and rapid release interface are more conducive to efficient cell collection and maximize DNA yield. The swabs have been sterilized with ethylene oxide and tested for human DNA contamination.

characteristic

Unique test matrix, greatly improved DNA yield

Adult oral swab yields 1 to 10μg DNA

is a good alternative to blood collection

Both humans and animals can use

Simple and fast operation

Available in single and double sterilized packaging

application

Genotyping studies

Veterinary Genotyping and Diagnostics

Parenting and Genetic Services

Forensic and DNA population research

Flocked Swabs and Custom Swab Manufacturing

Flocked Swabs and Custom Swab Manufacturing

When it comes to flocking sampling swabs, many people may only know that they are used for sampling by name, but they may not know the specific details. So what are flocking sampling swabs usually used for?

COVID-19 Testing Sampling

Throat swab: Professional operation is required, because the throat is more prone to injury, flocking swabs are the first choice.

ISO13485 quality management system for the production of disposable sampling swabs, quality standards, sterile swabs, disposable oral swabs, DNA flocking swabs, flocking swabs, foam swabs, disposable sterile swabs, disposable DNA swabs, Disposable virus sampling tube, oral cotton swab, sponge cotton swab, cloth tip cotton swab, cotton swab, medical cotton swab flocking swab.

Our factory specializes in the production and operation of: medical equipment flocking cotton swabs. Flocking sampling swabs: (DNA sampling swabs, cleaning verification cotton swabs); DNA extraction reagents and other products. The company has the right to import and export, and has obtained the certificate of free sale of medical equipment. Products are exported to Europe, America, Southeast Asia, the Middle East, Japan and South Korea. Send the sample to the laboratory for analysis. High quality sampling swab wholesale factory.

 

1. What is a flocking swab?

Flocking refers to the process of applying multiple lengths of fibers to an adherent coated surface; if the tip of the swab is flocked, it is a flocked swab. It is a disposable sampling swab composed of nylon short fiber fluff head and abs plastic rod. For oral nasopharynx, sampling, cervicovaginal sampling, laboratory testing, etc.

Flocked sampling swab samples are easy to collect.

Flocked sampling swab samples are easy to collect.

2. What are the advantages of flocking swabs for DNA collection?

Sample collection process: The unique structure of the flocked swab tip can greatly increase the number of samples collected

Sample extraction process: The brush-shaped layer structure can release approximately the entire collected sample.

3. Why use flocking sampling swabs? You will know after reading the comparison below.

Conventional fiber swab: The sample is trapped by the gaps in the fiber mass, that is, the sample is penetrated, diluted, and trapped in the fiber. The acquisition is slow, the release is even slower.

 

 

 

Nylon flocked swabs: Superior sample collection/release capability, >80% release rate

The time for flocking swabs to collect samples is 3-5 seconds, while the time for cotton swabs is 15-120 seconds, or even longer, which causes pressure on staff during the diagnosis process. Only faster sample extraction can complete the collection and analysis more efficiently.

3. Why are flocking swabs more advantageous for micro DNA collection?

Due to the internal structure of traditional cotton swabs, which are entangled with cotton fibers at the top, the sample will be dispersed by its fiber clusters and remain in the fibers during sampling, resulting in lower precipitation efficiency of DNA with low content, and even causing false negatives in the test. result.

The unique structure of the top of the flocking swab can almost completely extract and separate out a very small amount of DNA, so the flocking swab has a more obvious advantage in the collection of trace DNA.

3, ethylene oxide sterilization, independent packaging;

sampling step

Flocked Swabs and Custom Swab Manufacturing

Flocked Swabs and Custom Swab Manufacturing

Swab Step 1: Hold the handle and gently insert the sampling swab into the mouth.

Step 2: Gently rotate the sampling swab for 3-5 turns, then slowly take it out

Step 3: Put the extracted sample into the sample collection tube, break the handle, and seal it immediately to complete the sampling.

The newly developed sampling swab nylon flocked sampling swab head has soft flocking hair, and the absorption and release force is 3 times greater than that of trapping microorganisms in traditional sampling swabs, and it will not cause epithelial damage to patients.

The short nylon fibre acts like a soft brush, which can effectively improve the collection of cellular material; the capillary movement between the fibers forms a strong hydraulic pressure, thereby ingesting the liquid sample; at the same time, the sample is close to the surface of the swab and is easy to elute.