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Flocked Tip Swab

Flocked Tip Swab

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Flocked Tip Swab| China Flocked Swab Factory and Manufacturers.

Detection of viral nucleic acid sequence based on reverse transcription polymerase chain reaction (RT-PCR) is the main means for large-scale screening of new coronary pneumonia.

Generally, nucleic acid detection technology has the characteristics of early diagnosis, high sensitivity and specificity.

And it has the advantages of sample collection and preservation, personnel operation, nucleic acid extraction.

The performance of the kit is the cause of false negative or false positive test results.

Flocked swabs are the main samples for PCR. In the selection of raw materials, flocked glue plays a key role in the collection and release efficiency of swabs. Whether to use high-quality aqueous flocking glue is the main factor affecting the water absorption and hydrophilicity of fluff. The experiment is to compare the sample collection effects of swabs flocked with different glues.

What is a flocked tip swab？

The top of the flocking swab is a nylon fiber structure.

Nylon fibers are deposited on the surface of plastic rod in a certain direction by electrostatic field to form brush layer.

The layers are completely parallel and perpendicular to the inner rod surface.

Flocked tip swab brush head can effectively collect samples.

Flocked tip swab factory Product advantages.

The flocked swab can completely capture the cell sample through the directional friction effect of the brush fiber layer.

The capillary movement between the nylon fibers at the front end of the flocking swab can form a strong hydraulic pressure for absorbing liquid or cell line samples.

Cell samples can also be evenly and neatly concentrated on the near surface of brush fibers, so more than 95% of the samples can be released finally.

Cell Medical (Dongguan) Co., Ltd.  has many years of experience in medical application molding and flocking treatment heads and swabs.

Our flocked swabs are famous for their stable and reliable performance and excellent absorption and elution ability.

Cell medical (Dongguan) Co., Ltd. Daily production of millions of flocked sampling swabs

Cell medical (Dongguan) Co., Ltd. Daily production of millions of flocked sampling swabs. flocked tip swab 

COVID-19 Sample Collection and Transport kits

COVID-19 Sample Collection and Transport kits

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COVID-19 Sample Collection and Transport kits

Since the outbreak of the new crown, we have received many customer queries about which types of swabs, media and kits can be used for sample collection and transportation of COVID-19.

Cell medical (Dongguan) Co., Ltd. produce flocked swabs, VTM kits, virus transport medium, with multiple automatic production lines.

We support custom production, OEM and so on, and develop products with customers.

Our flocked swabs are famous for their stable and reliable performance and excellent absorption and elution ability.

Our VTM kits are manufactured in accordance with CDC and FDA guidelines.

Now let’s learn about sample collection and transport kits.

COVID-19 Sample Collection and Transport kits

COVID-19 Sample Collection and Transport kits

How do we collect COVID-19 samples?

Specimen collection requirements

Personal protective equipment (PPE) requirements for sampling personnel: N95 and above protective masks, goggles, one-piece protective clothing, double-layer latex gloves and waterproof boots; In case of contact with the patient’s blood, body fluids, secretions or excreta, replace the outer latex gloves in time.

Specimen type

1. Upper respiratory tract specimens: including pharyngeal swab, nasal swab, nasopharyngeal extract, etc.

2. Lower respiratory tract specimens

3. Stool samples: Patients with diarrhea symptoms need to collect stool samples.

Specimen collection method

Sampling flocked swab_Sample Collection

Sampling flocked swab_Sample Collection

1. Pharyngeal swab: wipe bilateral pharyngeal tonsils and posterior pharyngeal wall with 2 plastic rod swabs planted with pile at the same time, immerse the swab head into a tube containing 3ml virus preservation solution (isotonic salt solution, tissue culture solution or phosphate buffer can also be used), discard the tail, and tighten the tube cover.

2. Nasal swab: gently insert a plastic rod swab with a flocking nylon faucet into the nasopalatine part of the nasal canal, stay for a moment, and then slowly rotate and exit. Take another plastic rod swab with polypropylene fiber head and collect the other nostril in the same way. Immerse the above two swabs into the same tube containing 3ml sampling solution, discard the tail, and tighten the tube cover.

What kind of Media do you use to transport specimens?

Since the outbreak of COVID-19, the Virus Transport Medium has played a major role. Sample and nasal swabs are used to protect samples in the sample tube with virus preservation, which improves the accuracy of detection. Virus preservation solution is a solution for virus sampling, preservation and detection. What kinds of virus preservation solution are added to the virus sampling tube?

virus transport medium

virus transport medium

There are two types of virus preservation transport Media: inactivated and non inactivated.

The following briefly introduces several principles for the selection of virus preservation solution.

Non inactivated virus transport medium:

The non inactivated type does not contain lysate.

On the basis of Hank’s, BSA (bovine serum albumin) amino acids, vitamins and other nutrients required by the virus are added, which can maintain the activity of the virus in a wide temperature range and maintain the originality of the sample to the greatest extent.

For nucleic acid extraction and detection of the virus, virus culture and separation.

Characteristics of non inactivated preservation solution:

COVID-19 Sample Collection and Transport kits Use process

COVID-19 Sample Collection and Transport kits Use process

1. It can maintain virus activity for detection or virus isolation;

2. It has no inhibitory effect on subsequent nucleic acid amplification;

3. stored in cold storage(at 2 ℃ ~ 8 ℃ ).

Inactivation virus transport medium:

Inactivation preservation solution can inactivate the virus in the sample by fully mixing the collected sample with virus lysate and virus nucleic acid preservation solution, and effectively ensure the integrity of virus nucleic acid in the sample.

About the preserved viral RNA samples: used in gene detection, enzyme-linked immunosorbent assay (ELISA), PCR detection and so on.

Inactivation preservation solution includes guanidine salt containing and guanidine salt free.

1. Guanidine salt

(1) Instantly cleaved and inactivated to reduce the risk of sampling;

(2) Stored stably at room temperature for 2 weeks;

(3) It can match most nucleic acid extraction reagents.

2. Non refined salt

(1) Inactivated instantaneously to reduce the virus sampling risk, and the virus may recover its infectivity after dilution;

(2) Stored stably at room temperature for 2 weeks;

(3) It can match most nucleic acid extraction reagents.

3. Direct expansion preservation solution

(1)Inactivated instantaneously to reduce the virus sampling risk, and the virus may recover its infectivity after dilution;

(2)Stored stably in cold storage for 24-48 hours;

(3) Directly added to the nucleic acid amplification system as a template;

(4) Match most nucleic acid extraction reagents and nucleic acid release agents.

 

Flocked Swab Meaning

Flocked Swab Meaning

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Flocked Swab Meaning

This article will introduce what is the flocked swab, the purpose of the flocking swab, the application of the COVID-19 flocked swab and the material of the flocked swab, etc. The flocked swab manufacturer introduces. Give you a comprehensive understanding of flocking swabs.

what is the flocked swab?

Flocked Swab Meaning

Since the outbreak of COVID-19, the word “nasopharyngeal swab” has become a high-frequency word we talk about every day.

In recent months, the new crown pneumonia epidemic broke out again in countries all over the world. It’s worrying to watch the data released by WHO every day!!!

Flocked swab material

The flocked swab is made of nylon fiber flocking technology, and the front end is coated with nylon short fiber fixed vertically so that there is no absorption hole in the sampling area of the whole sampling swab, and the sampling sample will not be dispersed and retained in the fiber, which is conducive to faster and more efficient elution.

Traditional cotton swabs can not completely collect and elute samples while flocking swabs can elute 95% of samples. Therefore, the use of flocking swabs has great advantages for various sample collection applications.

The flocked swab is to deposit nylon fibres on the surface of the medical ABS rod in a certain direction through an electrostatic field to form a brush layer.

What is the purpose of flocked swabs?

Flocking swabs are the best choice for nucleic acid detection because they can better collect cell or biological samples at the collection site and release samples quickly.

Application: forensic medicine, DNA, microorganism, virus sampling, Oral swab, nasal swab etc.

What are flocked swabs used for in COVID-19?

The autumn and winter communication season is a period of the high incidence of common cold and influenza, and the most important means to control the epidemic situation is to select real patients with new crown pneumonia from a large number of respiratory tract patients.

At present, the most effective and widely used new crown sampling methods are nasopharyngeal swab and oropharyngeal swab sampling.

Flocked Swab Meaning _Application of flocking swab in COVID-19

Flocked Swab Meaning _Application of flocking swab in COVID-19

Nasopharyngeal swab collection method.

1. Keep the patient’s head still and remove the secretions on the middle surface of the anterior nostril;

2. Measure the distance from the nose tip to the earlobe with a swab and mark it with your fingers. Insert the swab into the nasal cavity in the direction perpendicular to the nose (face). When encountering resistance, it reaches the posterior nasopharynx, keeps the swab in the nose for 10 ~ 15 s, rotates it gently for 3 ~ 5 times, and take out the test flocked swab.

According to the American Society of Microbiology guidelines for the submission of clinical microbial specimens, the nasopharyngeal swab should be twisted on the nasopharyngeal mucosa, retained for 10-15 seconds, and then removed.

Feeling of nasal flocked swabs sampled by U.S. netizens.

netizens 01

netizens 01

It’s hard, and the tough guy still cries.

I have experienced both sampling methods.

It is not a painful cry, but a stress response caused by strong stimulation of the weak nasopharyngeal mucosa, with tears and tears.

netizens 02

netizens 02

No, as a girl, I don’t feel much about the nose swab sampling, except its excitement went to my head.

netizens 03

netizens 03

The more serious one is like eating mustard oil, and the lighter one is like blowing out your nose for several days.

Our netizens are so cute.

About oropharyngeal swab sampling.

oral swab sampling process_ Flocked Swab Meaning

oral swab sampling process_ Flocked Swab Meaning

Feeling of oral flocked swabs sampled by China's netizens.

Feeling of oral flocked swabs sampled by China’s netizens.

Pharyngeal(oral) swab: the collection process is faster (just a few seconds) and less painful, but you may feel nausea and vomiting, and some people have no obvious reaction.

As we are in the epidemic period, we should improve our awareness of self-protection when doing nucleic acid testing.

Flocked swab manufacturer introduces Cell medical (Dongguan) Co., Ltd.

Cell medical (Dongguan) Co., Ltd. is a comprehensive high-tech biotechnology enterprise.

We have invested a lot of scientific research strength to tackle key technical problems.

At present, our virus preservation tube and flocked swab have shown an irreplaceable role in the detection of new infectious diseases.

We support custom production, OEM and so on, and develop products with customers.

Welcome to leave a message for a consultation!

CONTACT US

Email:flockedswabs@gmail.com

What is a Nasopharyngeal Swab?

What is a Nasopharyngeal Swab?

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What is a Nasopharyngeal Swab?

COVID-19 Nucleic acid swab test  is a very effective and effective measure to prevent and control the new crown pneumonia epidemic.

The upper respiratory tract of human body includes nasal cavity, pharynx and throat.

That is to say, if people are infected with COVID-19, they can extract the nucleic acid of the virus in the nasal cavity, pharynx and larynx in 96 hours.

Therefore, we usually sample these locations in the rapid detection of new crown nucleic acids.

How to collect a nasopharyngeal swab?

Nasal swab sampling process

The first step is to collect secretions.

First, the medical staff will use a pharyngeal swab to wipe the subject’s nasal cavity or throat tonsils to collect salivary secretions.

nasal swab collection method

nasal swab collection method

The second step is to reserve samples.

After collecting the sample, immerse the nasopharyngeal swab in the preservation solution and screw on the tube cover to retain the sample.

The third step is to send samples for inspection.

Then, put the samples into clean sealed bags and send them to relevant parts for testing.

The fourth step is nucleic acid extraction.

Relevant departments will send the samples to the designated laboratory for nucleic acid extraction experiment.

Step 5: fluorescent PCR nasopharyngeal swab.

After collecting nasal samples, the experimenter uses fluorescent PCR to detect whether there is amplification reaction.

That is, to judge whether it is negative or positive.

Step 6:Finally, Receive test report.

Finally, according to the fluorescent PCR reaction results of nucleic acid detection, the nucleic acid detection vehicle inspection report is obtained, and I can query the results.

Sampling swab material

The sampling swab used for nasopharynx collection consists of a narrow rod made of a short plastic rod, one end of which is covered with an absorbent material. Such as cotton, polyester or flocked nylon.

The swab used for virus sampling should directly contact the sampling part.

The material of the sampling head is closely related to subsequent detection.

And the material requirements of virus sampling swab will be very high.

The virus sampling swab head shall be made of polyester (PE) synthetic fiber or artificial fiber.

Forbidden to use calcium alginate sponge or wooden swab (including bamboo stick).

However, calcium alginate and wood components can also absorb proteins after immersion in the preservation solution, and even inhibit the subsequent PCR reaction.

What are the advantages of using flocked sampling Nasopharyngeal swabs?

1. Flocked swabs provide better sampling.

Flocking swabs are a good choice for rapid diagnostic tests because they can better collect cells or organisms at the collection site and ensure the rapid release of the whole cell.

2. Enhanced diagnostic sensitivity.

Professional flocked technology turns each fiber into a velvet like swab, thus creating hundreds of thousands of contact points to better collect and release the collected samples.

Compared with non aggregated swabs, the increase in the number of target cells helps to improve the sensitivity of rapid diagnostic tests.

3. Rapid elution.

Their stable and reliable performance and excellent absorption and elution ability.

4. Easy handling and transportation.

sterilized and packaged separately, and the sterile swabs.

 

 

 

China Sterile Flocked Swab

China Sterile Flocked Swab Factory and Manufacturers

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China Sterile Flocked Swab GMP Factory and Manufacturers.

Cell medical (Dongguan) Co., Ltd. specializes in producing flocked swabs. Such as pharyngeal swabs, nasopharyngeal test swabs, oral swabs, nasal swabs etc.

Our flocked swabs are famous for their stable and reliable performance and excellent absorption and elution ability.

Our GMP Factory-We support custom production, OEM

Our GMP Factory-We support custom production, OEM

·OEM / ODM: support

·Certificate: CE / FDA / ISO certification

·GMP factory: Yes

·Supply capacity: 500000-1000000 pieces / month

·Size: 150mm

Sterile Flocked Swab flocked swabs manufacturers

Sterile Flocked Swab flocked swabs manufacturers

The DNA extraction flocked swab produced by our company is made by nylon fiber flocked technology. The front end is coated with nylon short fiber fixed vertically. There is no absorption hole in the whole collection swab collection area, and the DNA cells will not disperse and remain in the fibers, which is conducive to faster and more efficient elution.

Independent sterilization packaging.

The benefits of flocked swabs for COVID-19 viral collection.

1. Sample collection process: The unique structure of the front end of the flocking swab can greatly increase the number of samples collected.

2. Sample dissolution process: The brush-like layer structure can release almost all collected samples. There are more advantages for the collection of trace DNA.

3. According to different analysis items, the corresponding soft or brush texture swabs have reached the maximum collection.

4. Disposable sterile sampling swab rod with breaking point.Learn more

5. Flocked swab technology improves the adsorption/release of samples and the sensitivity of the analysis.

6. The front flocked swab sampling is more precise and suitable for extracting more cells from the nasopharynx.

7. Packed in a transparent plastic tube to avoid biological pollution.

In short, the upright nylon fibre is like a soft brush, which can collect more cell samples. The capillary action between nylon fibers enhances the load of aqueous samples, and the samples are concentrated on the surface of the swab, which is easier to elute. Nylon flocking swab can absorb and release more samples.

Cell medical (Dongguan) Co., Ltd.  –China Sterile Flocked Swab Factory and Manufacturers.

Email:flockedswabs@gmail.com

 

 

Sample Universal Viral Transport Medium Kits

Sample Universal Viral Transport Medium Kits

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Sample Universal Viral Transport Medium kits

Cell medical (Dongguan) Co., Ltd. disposable sample universal viral transport medium kits are composed of flocked swabs and test tubes with virus preservation solution (VTM).

The appearance of VTM is clear or red, and there are no precipitates, lumps and other insoluble visible foreign matters.

For collecting, storing and transporting human nasopharyngeal virus samples. Such as COVID-19, mycoplasma,  Chlamydia specimens collection, transportation and preservation.

Universal Viral Transport Medium for Viruses 

Test principle:

Virus: Composed of a nucleic acid molecule and protein or only protein, and the individual is small and the structure is simple. Because there is no cell structure, the virus cannot replicate itself, but invades its genes into the host cell, using the latter’s replication system to replicate new viruses. After the virus sample is collected, in order to maintain the viability of the virus sample and prolong the survival time of the virus in the sample, the sampling swab will be stored and transported in the transport medium.

Viral transport medium composition and inspection principle:

Viral Transport Medium

Viral Transport Medium

1. A combination of multiple antibiotics has broad-spectrum anti-bacterial and anti-fungal effects.

2. As a protein stabilizer, bovine serum albumin (BSA) can form a protective film on the protein shell of the virus, making it difficult to decompose and ensuring the integrity of the virus.

3. The neutral environment constructed by Hank’s buffer helps increase the survival time of the virus and the stability of infection.

4. Phenol red is an acid-base indicator, the discolouration area is 6.6 (yellow)-8.0 (red), and it will be red at 7.2-7.4.

The most stable pH of the outer protein of the virus is 7.2-7.4, which is also the pH range of Hank’s buffer.

If contaminated moulds or bacteria are not inhibited by antibiotics, they will multiply and release carbon dioxide to lower the pH. When the pH value is lower than 7.2-7.4, the stability of the outer protein of the virus will decrease and the decomposition will be accelerated. At this time, the appearance of the sampling solution will change from red to yellow.

What are the main components of  Viral Transport Medium(VTM)?

Hank’s solution base, gentamicin, fungal antibiotics, cryoprotectants, biological buffers and amino acids.

On the basis of Hank’s, adding HEPES and other virus stabilizing components can maintain virus activity in a wide temperature range, reduce virus decomposition speed and improve the positive rate of virus isolation.

How to use a universal viral transport medium?

Please read the instructions carefully before use.

Working conditions: room temperature

1. Take out the virus preservation solution.

2. Use a sampling swab for sampling.

3. Insert the swab into the tube containing virus preservation solution, break the tail, leave it in the preservation solution tube, cover the tube cover.

4. Store it at 2-4 ℃ and use it within 48 hours.

If it needs to be stored for more than 48 hours, please store it in the refrigerator at – 20 ℃.

VTM swab kit COVID-19: diagnostic vector transport medium.

VTM swab kit COVID-19: diagnostic vector transport medium.

Our VTM product features and advantages.

1. A virus transport medium (VTM) in line with the recommendations of who and CDC.

2. The product is safe, environment-friendly and non-toxic.

3. The universal viral transport medium adds special virus stabilizing components to maintain the structural stability of virus core protein and outer membrane protein for a long time.

4. It is especially suitable for influenza virus and other samples sampled through upper respiratory tract swabs.

5. Compatible with other detection reagents.

6. The reagent itself has a colour indication function, and obvious color change will occur when the product deteriorates, so as to avoid misuse caused by improper preservation.

Saliva Sample Collection Kit :Disposable saliva DNA RNA sampling tube

Saliva Sample Collection Kit :Disposable saliva DNA RNA sampling tube

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Saliva Sample Collection Kit :Disposable saliva DNA RNA sampling tube.

Non-invasive ! No blood, No needle.

No risk of infection, no need accompany of Doctor, no need refrigerate.

people can collection their Saliva sample at home and mail to Lab for DNA test.

what are the differences between the nasal swab and saliva tests for covid 19?

What is saliva collection kit?

In recent years, with the development of medicine, the examination technology has become more and more high-end. And the examination items have become more and more accurate.

Saliva is a complex mixture, which not only contains various proteins. It also contains DNA, RNA, fatty acids and various microorganisms. Therefore, it is possible to diagnose diseases by detecting saliva. Gene detection and analysis.

Saliva collector plays an important role in the process of collecting, transporting and storing saliva samples.

It is noninvasive and easy to self-management, and reduces the risk of medical staff exposure.

Saliva Collection Kit suitable for SARS-CoV-2 sample collection.

Nucleic acid detection is the most widely used new crown detection method.

Including PCR nasopharynx swab, oropharyngeal swab  and saliva sample test.

High precision. As long as the collection, breeding and separation of nucleic acids are successful, there is basically no false positive or false negative.

But the sampling staff are easy to be exposed and the risk is high; With one more step of extracting nucleic acid, unskilled technicians are likely to fail to extract, resulting in false negative, or pollute with other people's samples, resulting in false positive.

 

How to use saliva sample collection kit

saliva process 01

 

1.Before collecting saliva,relax your cheeks andgently massage cheeks with fingers for 15~30 seconds to produce saliva. Gently

2mL  saliva into thefunnel until the liquid saliva(non-bubble)reaches the height of 2.0 ml scale line. Saliva samples collected shall be free of impurities and sputum.Don't spit all over the vial.

saliva process 02

 

2.Hold the Hold the storage vial in hand and keep it upright, then insert the bottom of storage vial into the saliva collection cup, and screw down. Then the storage liquid in the vial will flow into the saliva collection vial.

Saliva Sample Collection sampling process 03

 

3.Keep the collecting vial upright, unscrew the funnel, take out the clean saliva collecting vial cap from the packing box,screw and tightenit on the saliva collecting vial. The vial caps have a chok-ing hazard. Keep out of reach of children.

Saliva process 03

 

4.Shaking Turn the collecting vial upside down for 10 times to fully mix saliva ten times and preservation solution.

Saliva process 05

 

5.Take out a bar code from the packing box and stick it on the saliva collecting vial, then put the collecting vial with bar code and two bar codes into the sample bag for storage, transportion or testing, and the remaining bar code is kept by the user for subsequent information feedback.

COVID-19 Pooled Sample Testing:Improve sampling rate and reduce cost

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COVID-19 Pooled Sample Testing:Improve sampling rate and reduce cost.

With the advent of autumn and winter, the possibility of a new outbreak of COVID-19  is increasing.

COVID-19’s large-scale community screening is the main means to cope with the recent outbreak of small-scale epidemics at home and abroad.

At present, New Coronavirus’s mixed sample nucleic acid detection has become a routine method to effectively enhance the screening and detection of nucleic acid in community population.

The pooled sample test of covid-19 increase the sampling rate and meet the growing needs of low-risk populations.

Virus transport medium,disposable virus sampling tube

Virus transport medium,disposable virus sampling tube

What is a Pooled Sample Test?

“mixed detection”, that is, nucleic acid test of Pooled Sample.

On the one hand,it is a method to sample several people, such as 3 or 5 or even 10, and then put them into the same virus sampling tube.

On the other hand,pooled Sample means combining the same type of specimen from several people and conducting one NAAT laboratory test on the combined pool of specimens to detect SARS-CoV-2.

What is the significance of nucleic acid test in Pooled Sample?

COVID-19 Pooled Sample Testing Advantages

Because a virus sampling tube only puts one person’s sample, the cost will be very high, and the detection time is long, which is not suitable for large-scale nucleic acid detection.

In principle, the single sample sampling mode is only applicable to high-risk areas and key populations.

In order to improve sampling efficiency, shorten sampling time and reduce sampling cost. Multi Country selection of Pooled sample test scheme.

For example, when 5-in-1 mixed sampling test is used, the result is negative, which means that all five people are negative.

On the contrary, once positive or weak positive is found, it will be traced immediately.

Re collect single tube swabs for review, and then determine which of the 5 people is positive.

Therefore, the cost of 5-in-1 mixed mining is relatively low.

This also caused the 5-in-1 mixed sampling mode to be five times faster than the previous mode of using a virus sampling tube for a human sample.

One of the biggest disadvantages of sample merging is the decrease of associated test sensitivity.

Analyzing multiple samples in a single reaction effectively improves the flux, but it also dilutes a single sample and may reduce the weak positive signal from outside the detection limit.

In short, pooled sample testing is mainly used for large-scale screening to check asymptomatic coronavirus infected persons. It is suitable for large-scale testing projects such as schools, factories, units and urban areas. It has the advantages of efficient screening and resource saving.

Although reduced detection sensitivity is acceptable for screening services in asymptomatic populations.

However, When providing diagnosis for high-risk or symptomatic patients, we must give priority to the accuracy of the results.

The special preservation tube for Pooled Sample test uses medical grade PP as raw material, unique structural design and manufacturing process to prevent liquid leakage. And has the characteristics of high temperature resistance, high pressure resistance and high-speed centrifugation resistance.

Cell medical (Dongguan) Co., Ltd. produces virus sampling tubes of various specifications, both inactivated and non inactivated, disposable virus sampling tubes, pooled sample sampling tubes.
such as 1ml, 2ml, 3ml, 5ml, 10ml and other specifications.

Located in  Guangdong Province, in China,with complete qualifications.

Contact information required.E-mail:flockedswabs@gmail.com

 

Pcr test nasal swab and an antigen test difference for covid 19

Pcr test nasal swab and an antigen test difference for covid 19

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Pcr test nasal swab and an antigen test difference for covid 19

What is COVID-19?COVID-19 is an epidemic disease caused by SARS-CoV-2. An acute respiratory infectious disease broke out at the end of 2019. So far, WHO has been making the latest tracking report on the new pneumonia on the Internet every day.

What are the current methods of COVID-19 test?

Virus detection includes two types: nucleic acid amplification test (NAAT) (PCR test) and antigen test.

Antibody tests (also known as serological tests) can prove whether you have been infected in the past.

What is the COVID-19 PCR test?

PCR (polymerase chain reaction): similar to the natural replication process of DNA, its specificity depends on oligonucleotide primers complementary to both ends of the target sequence.

Basic principle: the basic principle of PCR technology is similar to the natural replication process of DNA. Its specificity mainly depends on the oligonucleotide primers complementary to both ends of the target sequence. It consists of three basic reaction steps: denaturation, renaturation and extension.

PCR test sample collection method include:

If the sample contains a virus, the researchers will extract its RNA.

Why use the PCR test ?

PCR nucleic acid examination is a direct detection of COVID-19 RNA in human body by sampling from the nasal cavity. The structure of virus is composed of DNA or RNA combined with external lipid protective capsule. Therefore, direct detection of virus DNA itself is the most accurate, fastest and effective new detection method. PCR nucleic acid test can detect infection immediately after the human body obtains the virus, and the accuracy is much higher than antibody test.

ABOUT PCR TEST_Pcr test nasal or Throat swab sampling

ABOUT PCR TEST_Pcr test nasal or Throat swab sampling

How does the PCR test nasal swab work?

Nasopharynx swab is to wipe the secretion of the patient’s nasal cavity or pharynx. And then make the secretion into smear for examination and bacterial culture to clarify what bacterial infection is in the patient’s nasal cavity and pharynx.

Nasal swab sampling procedure

1. Keep the patient’s head still and remove the secretions on the middle surface of the anterior nostril;

2. Gently and slowly insert the swab through the nasal cavity to the nasopharynx;

3. After encountering resistance, it reaches the posterior nasopharynx and stays for several seconds to absorb secretions;

4. Gently rotate and take out the swab and place it in the transport medium;

5. For the swab used for virological test, immerse the swab head into the virus delivery medium, discard the tail, and tighten the tube cover;

If it is necessary to collect from both nostrils, the sampler should use the same swab.

How does the antigen test work?

Rapid antigen detection can play an important role in guiding patient management, public health prevention and control decision-making and covid-19 monitoring.

It is especially valuable for grass-roots areas that may hinder clinical diagnosis and control due to lack of nucleic acid detection capacity or long detection time.

According to WHO, high specificity based on antigen detection indicates that the positive results indicate new crown virus infection.

For patients within 9 days of onset, sampling personnel can use antigen detection as a diagnostic test.

Especially for the staff of medical institutions, inpatients and visitors in the epidemic area.

When nucleic acid detection cannot be effectively implemented, antigen detection can be used as an important screening method.

Rapid antigen test sampling procedure.

Rapid antigen test sampling process

Rapid antigen test sampling process

 

Generally speaking, nucleic acid detection: it has high requirements for laboratory environment, detection personnel and instruments. The detection has high sensitivity and good specificity.Generally, we can get the results in 2-3 hours.

Antigen detection: it has low requirements for the laboratory. For early screening and early diagnosis. It is suitable for large-scale screening in grass-roots hospitals. we can obtain the results within 15 minutes at the fastest.

At present, PCR test nasal swab is widely used, and the sensitivity and specificity of antibody / antigen detection reagents are still limited. 

Each has its own emphasis and cannot replace each other. We should combine multiple virus detection methods.

It can effectively shorten the detection window period and improve the positive detection rate.

 

Disposable virus sampling medium

Disposable virus sampling media 10ml transport tube for sample collection

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Disposable virus sampling media with 10ml transport tube for sample collection.

Product Description

Disposable virus sampling tube

Disposable virus sampling tube

Product name:Disposable virus sampling tube.Keyword:sample collection kit,virus sampling medium.

Function:sample collection,storage,transport virus.

OEM/ODM: accept.

Place of Origin: Guangdong, China.

Disinfecting Type: EO.

 

 

Sampling tube specification

Sampling tube specification

 

Properties: Medical Materials & Accessories.

Tube Volume: 5/10ml.

Stock: yes.

Shelf Life: 12 months.

Material: PP.

Quality Certification: ce,MSDS.

Instrument classification : Class I.

 

Virus DNA / RNA sample preservation solution (inactivated or non)

I believe that my friends must be very curious when they first came into contact with this term. Virus DNA / RNA sample preservation solution, also known as cell preservation solution, virus transport medium or disposable virus sampling tube.

What is a virus transport medium?

First, the virus preservation solution is a liquid that immerses the sampling swab virus sample in the sampling tube and protects the detected substance (DND or RNA) of the virus.

It is mainly used for the collection, preservation and transportation of common virus samples such as New Coronavirus, hfmv, influenza virus and so on.

Researchers can use it to collect throat swabs, nasal swabs, or tissue samples from specific sites.

The samples are stored in a disposable virus sampling tube, which can be used for subsequent clinical experiments such as nucleic acid extraction or purification.

We divide virus transport media into two types, one is non inactivated and the other is inactivated.

The non inactivated type can protect virus protein and nucleic acid, preserve virus activity and facilitate culture and detection.

The inactivated type makes the virus no longer have physiological activity, lose infection and disease, and have fecundity, which can inactivate the virus.

Eliminate secondary infection and protect the safety of transportation and testing personnel.

Because the virus is a parasite, it cannot survive in vitro after sampling. If it cannot be detected in time, it needs to be stored in virus preservation solution.

In order to protect the security of virus detection environment and detection personnel, our virus inactivation preservation solution comes in handy.

Some friends may wonder if the inactivated type will inactivate the virus? How can we check it?

Don’t worry, the purpose of using inactivated preservation solution is to lyse nucleic acid.

Release nucleic acid and then detect nucleic acid through subsequent real-time fluorescent RT-PCR to judge whether the sample contains virus characteristic nucleic acid, that is, whether it is infected with virus.

The virus has a single structure and contains only one nucleic acid and protein. Therefore, the virus is detected when the characteristic nucleic acid is detected.

Then some friends will ask, since the detection is so simple, why do you need virus preservation solution? What role does it play?

Usually, after virus sampling, not all samples can be transported and stored at the sample collection place.

Therefore, we need to transport and retain the collected virus swab, otherwise the virus nucleic acid will degrade quickly and the nucleic acid cannot be detected.

Therefore, we need to add preservation solution to the sampling tube to prevent the virus nucleic acid from being degraded so quickly.

Cell Medical’s virus preservation solution allows viral DNA/RNA to be stored and transported at room temperature for 1 week without degradation.

After extraction using most commercial kits, the obtained DNA/RNA is of high quality and high yield, and can be used for various gene testing and analysis experiments, such as PCR and qPCR, while saving transportation costs.

Cell Medical’s inactivated virus storage fluid uses a small volume storage fluid compared to the large volume storage fluid of a traditional virus sampling tube, which avoids excessive dilution of the collected samples and increases detection sensitivity.

And our inactivated virus storage solution is so easy to use that you can take samples at home.

Moreover, our inactivated virus preservation solution is simple and convenient to operate. You can take samples at home.

Well, if you have anything you don’t understand or want to consult, please leave us a message.

We will have a professional doctor and my little brother will let you answer.

About us

Cell medical (Dongguan) Co., Ltd. is a professional manufacturer and supplier of sampling swabs and virus sampling tubes.

We produce flocked swabs, VTM kits, virus transport media, with multiple automatic production lines.We support custom production, OEM and so on, and develop products with customers.

Welcome to consult us.

Email:flockedswabs@gmail.com.