COVID Swab test

COVID Swab test : How can I do a Swab Test

From last year to now, the epidemic has changed our way of life. Working from home, quarantine, temporary unemployment, children taking early leave or schooling at home, and less seeing family, friends, and colleagues, many changes require us to adapt.

Since late December 2021, the epidemic in Hong Kong has worsened sharply after the Chinese New Year. On February 5, Hong Kong recorded 300 new positive test cases every day, setting an epidemic record; two days later, the number rose to 607; it exceeded 1,000 for the first time on February 9, and exceeded 2,000 on the 14th.

In the face of the pneumonia epidemic of new coronavirus infection, how should we conduct swab tests? How can we do personal protection in our daily life?

The new coronavirus is transmitted through the respiratory tract, and the pharynx is the place where such viruses gather more. Throat swab samples are medical cotton swabs, which are dipped in a small number of secretions from the pharynx of the human body, and the samples taken are throat swab samples. the virus type.

How can I do a swab test?

Cell medical (Dongguan) Co., Ltd., a professional VTM kits and swabs manufacturer, disposable swab tubes exporter, has many years of experience in medical application molding and flocking treatment heads and swabs.

When performing a swab test, we make the following recommendations to the sampler:

  1. Residents are encouraged to blow their noses to clear their nasal passages.
    If residents cannot perform this task, wipe their nostrils with a flocked swab or tissue.
  2. The Resident’s name, date of birth and time of collection are affixed to the vial.
  3. hand hygiene. Wear a mask, goggles and gloves.
  4. With the head in a neutral position, insert the dry swab from the nostril straight back (not upward) along the base of the nasal passage until it reaches the posterior wall of the nasopharynx—usually halfway from the corner of the nose to the front of the ear (about 4~4~ 6 cm or 1.6-2.5 inches).
  5. Gently swirl the flocked sampling swab and let it sit for a few seconds.
  6. Carefully remove the flocked swab without touching the sides of the nostrils.
  7. Open the virus sampling tube (VTM Tube) and place the swab in the transport medium.
  8. Break the flocked swab along with the swab Breakpoint and close the cap.
  9. Place the sample (viral sampling tube) in the inner bag of the plastic biohazard bag.
  10. Remove gloves for hand hygiene; remove masks for mouth hygiene.
  11. Complete the application form and place it in the small outer bag of the plastic biohazard bag.
  12. Place the entire plastic biohazard bag in a separate clean paper or ziplock bag.
  13. Refrigerated specimens.
  14. shipped to the laboratory.

How can we do personal protection in our daily life?

1. Wash your hands frequently and maintain good respiratory hygiene.

Wash your hands under running water with soap or hand sanitiser.
Practice good respiratory hygiene. Cover your mouth and nose with a tissue or towel when coughing or sneezing, wash your hands after coughing or sneezing, and avoid touching your eyes, nose or mouth with your hands.

2. Enhance physical fitness and immunity, keep the environment clean and ventilated.

Enhance physical fitness and immunity, eat a balanced diet, exercise moderately, work and rest regularly, and avoid excessive fatigue.
Open windows for ventilation no less than 3 times a day, 20 to 30 minutes each time.

3. Minimize activities in crowded places and pay attention to symptoms.

Minimize activities in crowded places and avoid contact with patients with respiratory infections.
If you have respiratory symptoms such as cough, runny nose, and fever, you should isolate and rest at home, and seek medical attention as soon as possible if the fever persists or the symptoms worsen.

4. The role of handwashing in preventing respiratory tract-borne diseases.

Proper handwashing is one of the most effective measures to prevent diarrhea and respiratory infections. The Chinese Center for Disease Control and Prevention, the World Health Organization, and other authorities recommend washing hands with soap and water (water).

5. What should I do if there is no clean water outside the trip and it is inconvenient to wash hands?

You can clean your hands with alcohol-based sanitisers. Coronaviruses are not acid and alkali resistant and are sensitive to organic solvents and disinfectants. 75% alcohol can inactivate viruses, so a certain concentration of alcohol disinfection products can be used as an alternative to soap and running water for handwashing.

 

Do a good job of COVID-19 nucleic acid swab testing, maintain a healthy lifestyle, and do personal hygiene. During the epidemic, follow the principles of going out less, wearing masks, washing hands frequently, actively isolating, and maintaining personal and home hygiene.

Dog DNA Tests

Dog DNA Tests_The owner is isolated and the pet needs swab test!

A few days ago, a patient in the USA, was diagnosed with a COVID-19 infection. Due to the quarantine, no one at home is taking care of the pet dog. So she turned the dog over to the US Animal Protection Service.

The site is responsible for monitoring animal welfare and controlling animal and plant infectious diseases, such as foot-and-mouth disease, bird flu and other animal diseases.

The staff suddenly wondered if the dog also carried the new coronavirus-19. Therefore, the staff took swabs (secretions and feces) samples from the dog’s mouth, nose and anus for the new coronavirus nucleic acid test.

The new test results were unexpected: the oral and nasal swabs of the new coronavirus-19 were weakly positive in the swab test, and the anal swab test was negative.

However, the symptoms of COVID-19, such as fever and cough, look very lively and healthy.

The transmission of COVID-19 to pets has been the focus of discussion in the scientific community.

Currently, the Society’s Animal Residence has only tested this dog. Not sure if other animals have the same problem.

Subsequently, staff stepped up protective measures for the animal shelter and disinfected its facilities, walls and floors. Out of an abundance of caution, staff also isolate the dogs and observe them closely.

The person in charge of the animal protection station said that the dogs will be re-examined after that.

Although the pet dog had no symptoms of Covid-19 infection, the discovery of suspicious evidence of Covid-19 infection for the first time really took the world by surprise.

The swab test for COVID-19 was weakly positive, with both false positives and positives.

If the dog’s new coronary pneumonia swab test is finally positive, there are two possibilities: one possibility is that the dog is also infected with new coronary pneumonia; the other possibility is that the dog brought the virus into the mouth or Nasal, i.e. mechanical carry.

A dog’s mouth, nose and ground compared to a human. Surfaces with closer contact and smell habits are more likely to inhale some pathogens, including COVID-19 that may be present in the environment.

It is worth noting that the current medical institutions pay more attention to the diagnosis and treatment of infected patients; the CDC pays more attention to the source of the new coronavirus-19 infection and adopts various prevention and control measures. Few institutions test animals that are closely related to people, such as pet dogs, domestic cats, livestock, and even domesticated birds.

Whether these closely related animals carry the new coronavirus disease as a vector of infection or transmission; or whether dogs can be infected with the new coronavirus is unclear.

Dogs themselves can also be infected with coronaviruses, but the common coronaviruses that dogs contract cannot infect humans;

why?

The cat is being made a swab test

The cat is being made a swab test

Generally speaking, a virus needs to enter an animal or human cell in order to infect, replicate, and cause disease.

First, the virus must recognize receptors on the surface of the cell it wants to invade.

For example, SARS-CoV-2 needs to bind to a receptor called angiotensin-converting enzyme 2 (ACE2) to infect humans and cause disease, which is the equivalent of a key to a lock.

The virus then binds to a receptor expressed by the cell, the virus integrates into the cell, and infects the cell.

The ultimate determinant is its genetic material and genes (the material basis is DNA).

Obviously, the DNA of animals and humans is different, and the proteins expressed on the cell membrane are also different. Sometimes it looks the same. As long as

several amino acids are related, the profile of the protein is different and the virus cannot bind to it.

However, this is not absolute, as the virus is constantly mutating and adapting to the environment.

If the new coronary pneumonia can be directly transmitted across species, it can indicate that this virus infection is a zoonotic disease, which is obviously very bad.

A warm reminder from Dr Lee:

We found weak nucleic acid positive for New Coronavirus disease in pet dogs.

This message tells us:

1. In addition to guarding against infection by infected persons, it is also necessary to avoid close contact with active animals, including pets living together for a long time;
2. If you accidentally touch these animals, you must wash your hands afterwards;
3. Wear a mask and do a good job of protection before touching animals as a last resort;
4. During the epidemic, we suggest taking good care of pets and do not take pets for a walk outdoors.

Nylon Flocked Swabs

Nylon Flocked Swabs

During an outbreak, everyone should be familiar with sampling swabs. When doing nucleic acid, touching the nose and throat is directly touching the sampling site of human organs, that is, directly touching our human organs. Therefore, the material of the sampling head will affect our comfort and is closely related to the subsequent detection.

Sampling swabs should be polyester, nylon and other non-cotton, non-calcium alginate swabs, and the handle should be non-wood. The breakpoint is located about 3cm from the top of the swab head, which is easy to break.

NASAL FLOCKED SWAB

NASAL FLOCKED SWAB

Moreover, the experimental analysis shows that the extraction efficiency of nylon flocked swabs is the highest. In contrast, the recovery efficiency of nylon flocking swabs is also higher than that of other material swabs.

Nylon fibre flocking technology. The front end is coated with vertically fixed nylon short fibers, so that the entire sampling area of ​​the sampling swab has no absorption holes, and the sampling sample will not be scattered in the fibers, which is conducive to faster and more efficient sampling!

Compared with traditional winding swabs, nylon flocking swabs collect and release 3 times the number of samples, do not damage cell samples, ensure the survival rate of cell samples, do not leave fatty acids, do not affect the test and detection results, not to mention Said to cause harm to the human body.

What materials cannot be used for sampling swabs?

As we all know, the materials of medical swabs have always attracted much attention. After all, medical swabs come into direct contact with the skin. People who touch the skin can first touch alcohol for disinfection, that’s fine, but what about those who have direct contact with organs? For example, the throat swab we are most familiar with during the epidemic.

The throat swab is in direct contact with the sampling site, and the material of the sampling head is closely related to subsequent testing. The sampling swab head should be made of nylon flocked swabs or rayon, and calcium alginate sponges or wooden stick swabs (including bamboo sticks) should not be used.

Cotton products should not be used for the swab head, because the cotton fiber has strong adsorption to protein and is not easy to clean into the subsequent storage solution; wooden.

What are the types of swab tests?

There are two different types of COVID tests – Swab tests and antibody tests.

1. Swab tests can show if you have an active coronavirus infection and should take steps to isolate or isolate yourself from others. There are currently two types of diagnostic tests – molecular (RT-PCR) tests that detect the genetic material of the virus, and antigenic tests that detect specific proteins on the surface of the virus. Samples are usually collected with a nasal or throat swab, or saliva spits into a test tube.

2. Antibody tests look for antibodies that the immune system produces in response to a threat, such as a specific virus. Antibodies can help fight infection. Antibodies can take days or weeks to develop after infection and may remain in the blood for several weeks after recovery.

Therefore, antibody tests should not be used to diagnose active coronavirus infection.

Right now, researchers don’t know whether the presence of antibodies means you’ll be immune to the coronavirus in the future. While there is a lot of uncertainty surrounding this new virus, the widespread availability of antibody testing and clinical follow-up over time also has the potential to provide the medical community with more information about whether and how long a person has recovered from the virus of people have a reduced risk of infection if they are re-exposed to the virus. Learn more about antibody testing.

Virus Transport Medium Composition

Virus Transport Medium Composition

VTM Transport Medium

Transportation Medium Specifications

2.0ml, 3.0ml, 4.0ml, 5.0ml, 6.0ml.

Application

For transport storage of clinically collected samples.

Virus Transport Medium kits

Virus Transport Medium kits

Virus Transport Medium Composition

Hank’s balanced salt builds a neutral environment; bovine serum albumin as a protein stabilizer and Hank’s balanced salt increase the survival time and infection stability of the virus; antibiotics have broad-spectrum antibacterial effects; acid-base indicator, pH 6.6 in the discoloured area (yellow) to 8.0 (red), red at pH 7.2 to 7.4.

Storage condition: 4-25℃ Validity period: 12 months.

How to use VTM Kits?

1. According to the sampling requirements, use a sampling swab to collect samples.

2. Place the sampling swab after sample collection into a sterile sampling tube. 3. Break the swab at the breaking point of the sampling swab rod and discard the tail. 4. Tighten the cap of the sterile sampling tube.

5. Label the sterile sampling tube with information as required.

6. Specimens should be transported to the corresponding influenza surveillance network laboratory within 2 working days after collection, and the storage temperature should be 2-8°C; Save and ensure that the collected specimens are sent to the corresponding network laboratory within 1 week. Specimens should avoid repeated freezing and thawing.

how to use flocked swabs

how to use flocked swabs

7. For specific sampling methods, please refer to the following:

1) Throat swab specimen: Use a special sampling swab to wipe the posterior wall of the pharynx and the tonsils on both sides with moderate force, avoiding touching the tongue; quickly immerse the swab head in the sampling solution, and it is easy to break at the sampling swab rod. The swab is broken at the cut-off point and the tail is discarded. (Applicable to this product sampling)

2) Nasal swab specimen: use a special sampling swab, gently insert the swab head into the nasal palate, stay for a while and then slowly turn it to exit; quickly immerse the swab head in the sampling solution, and the swab head is easy to remove in the sampling swab rod. Break the swab at the cutoff point and discard the tail. (Applicable to this product sampling)

The Mission of A Virus Test Swab

The Mission of A Virus Test Swab

The Mission of A Virus Test Swab

From the sampling point to the testing room, then to the temporary storage point of medical waste.

Then to the hazardous waste centre, to the power plant, and finally to the soil.

A swab for nucleic acid detection completed the task and became a piece of pollution-free ash and fill it in the soil.

At present, we are in a critical period of anti-epidemic.

An ordinary hospital has a maximum of 11,220 samples per day at a single sampling point.

The Mission of A Virus Test Swab

The Mission of A Virus Test Swab

At nine o’clock in the morning, at the nucleic acid testing and sampling service point, citizens who were ready to test lined up.

Everyone wears a mask and consciously separates one meter from each other.

At the beginning of the inspection window, the heavily armed nurses washed their hands with an antiseptic solution.

And then removed a flocked swab about 15 cm long from the packaging bag to take a sample before taking the throat swab.

The nurse opened the collector’s mouth wide, and she skillfully inserted the flocked swab into her pharynx.

Then picked up a sampling tube (virus transport medium) with her left hand. And inserted the collection stick into the sampling tube with her right.

With a little force, the tip of the cotton swab breaks enters the sampling tube, seals it. And throws the long stick into the yellow medical waste bin.

As a testing point for ordinary citizens and inpatients, as an ordinary citizen and inpatients, the use of cotton swabs in an ordinary hospital reached 11,220.

Medical waste treatment forms closed-loop management in nucleic acid testing laboratories.

Take the flocked swab, put the swab head into the sampling tube, and paste a barcode similar to “ID card”. And carefully seal it, put it into a transparent sealed box.

And then send it to the transfer cabin of the PCR laboratory of the Department of Infectious Diseases by staff wearing protective clothing.

The PCR laboratory is under negative pressure, and after the virus enters, it cannot come out. After the outbreak, the PCR laboratory strictly abides by the medical waste treatment process, forming closed-loop management of the laboratory.

An hour later, staff in protective suits transported medical waste out of the ward in sealed yellow bags and sealed with “extremely infectious waste”.

Then, the workers send these medical wastes by trolleys to the medical waste temporary storage area at the nucleic acid collection point 100 meters away. For the medical wastes for nucleic acid testing, he transports an average of about 35 kilograms per day.

We need to place the virus sampling tube for 48 hours during the transfer process

Except for professionals, our PCR laboratory does not allow patients and the public to enter here.

To ensure safety, all medical waste from nucleic acid testing collection points, including swab sticks, is kept here for 48 hours.

After our test results come out and are confirmed to be correct, they will be sent to the hazardous waste treatment centre by a medical waste transfer vehicle.

At ten o’clock in the morning, the staff of the hazardous waste centre arrived at the scene. Unload the empty shipping box and load the ship with medical waste that has been sitting for 48 hours.

The sampling flocked swabs used must be incinerated at high temperatures above 1100°C.

There are two buildings, an incineration workshop and a cooking room, in the yard of the Hazardous Waste Center.

The staff in protective suits skillfully unload boxes of medical waste from the transfer vehicle and load boxes of hazardous waste into bucket elevators.

 

Why Choose Anal Swab Covid Tests

Why Choose Anal Swab Covid Tests

Why Choose Anal Swab Covid Tests

A friendly netizen said,

“The anal test first asks you to take off your pants and lie on the bed,

The paramedic then stabs (anus) twice with an anal swab,

shallow once deep

In addition to the endless shyness in the whole process,

Nothing else feels like it! ”

A shy handsome man

A shy handsome man

 

Xiaolee will tell you why you need to do anal swabs.

Currently screening for COVID-19,

Mainly use an oropharyngeal swab and nasopharyngeal swab nucleic acid detection,

Because of its convenience and speed, it is suitable for large-scale screening;

Nasopharyngeal Swab Sample

Nasopharyngeal Swab Sample

However, some asymptomatic or mildly infected people,

The disease recovered quickly after infection,

Nucleic acids in the respiratory tract and pharynx are undetectable within 3-5 days.  

longer duration of nucleic acid-positive stool or anal swab,

Therefore, adding anal swabs can improve the detection rate,

Effectively reduce the probability of false negatives,

Reduce missed diagnoses!

One of the anal swab sampling poses

One of the anal swab samplings poses

 

Friends who have done nucleic acid swab tests have experience,

In previous tests,

The most uncomfortable part should be the part of the nasopharyngeal swab,

To poke the nose is to poke deep into the soul.

According to the description of the anal swab recipient,

“The whole process was lying in bed and the medical staff helped.

Insert the tip of the sampling cotton swab into the anus and turn it a few times.

Twice in total, each for about 10 seconds.

Although a little surprised and a little embarrassed,

But understandable and bearable,

After all, this rule is for everyone’s sake. ”

Many Chinese friends who have returned to China for quarantine

I have also experienced the subtle taste of it.

 

 

What is Pooled Sample?

What is Pooled Sample Test?

Pooled Sample Test?

With the 2019 coronavirus disease (COVID-19) pandemic, doing a good job in viral nucleic acid detection is the top priority. However, detection of the virus is still limited due to resource constraints. Pooled sample testing offers a way to significantly improve testing power.

“mixed nucleic acid test”  or “Pooled Sample Test”, referred to as “mixed test”.

Which means that two or more samples are mixed and tested. method for positive samples.

     What is the difference between the “mixed collection” of community nucleic acid testing and the “single collection” of the hospital?

    Why do community streets adopt the mixed mining model?

    Under what circumstances should I test individually?

What is pooled COVID testing?

The so-called “mixed detection” of nucleic acid.

Takes throat swab samples from multiple people and puts them together for viral nucleic acid detection.

Pooled Sample Test VTM Kits

Pooled Sample Test VTM Kits

In fact, Medical use of Pooled Samples is common.

In blood collection systems such as apheresis stations.

We use pooled samples to detect the presence of infectious disease antigens and antibodies in pooled samples of multiple people.

There are two modes of “mixed detection”. One is to sample several people, such as 3 or 5 people and put them into the same sampling tube.

The other is to mix samples of the same volume from 3 or 5 people during laboratory testing, also known as “sample mixing”.

From a scientific point of view, the first “mixed sampling” mode will not affect the sensitivity of nucleic acid detection. While the latter mode of mixed detection of samples has a certain impact on the sensitivity of the detection,  the degree of impact is controllable.

In order to detect high-risk groups, such as symptomatic patients and close contacts in fever clinics, we still recommend separate sampling.

For screening of low-risk groups, pooled sample test is our first choice.

Is the mixed detection technology reliable?

Is the “five-in-one” and “ten-in-one” mixed mining detection technology reliable?

“The size of the single-collection tube and the mixed-collection tube are different, and the amount of the preservation solution is also different.

Based on the results of a large number of basic experimental research and practical operations in the previous period.

The increase in the volume of the mixed-collection preservation solution has no effect on the detection results of weakly positive specimens.”

In the case of an extremely low positive rate, the 10-in-1 mixed detection technology is very efficient.

The FDA is aware that there is a great interest in performing testing using pooled samples.

This approach increases the number of individuals who can be tested with the same amount of resources.

What are the benefits of mixed nucleic acid detection?

The hybrid detection of nucleic acid has greatly improved the nucleic acid detection capability, reduced the burden of personal testing costs, and did not affect the time for issuing the test report.

The testing time of a single test and mixed test laboratory is the same, but compared with a single test, the mixed test is more suitable for mass and group screening.

In the case of small-scale outbreaks, the use of mixed detection can improve efficiency, play the role of multiple screening, early diagnosis, reduce transmission, and save social costs.

Whether the population is suitable for mixed testing shall be carried out in accordance with the requirements of the provincial and municipal epidemic prevention and control headquarters,

The medical institutions carrying out the testing must follow the technical requirements and standards of the municipal health department.

Which groups recommend the single purchase and single inspection?

It is worth mentioning that single sampling and single inspection are recommended for specific populations.

The above notice specifically mentioned that COVID-19 nucleic acid 10 in 1 and 5 in one mixed detection technology is suitable for large-scale rapid screening of the low-risk populations, and is more suitable when the overall positive rate of population is low (0.1%).

However, for the detection of high-risk groups such as symptomatic patients, close contacts and people in key areas in fever clinics.

Recommended to adopt single sampling and single detection.

What should I pay attention to when doing pooled sample detection?

1. When going to the testing point for nucleic acid testing, wear a mask, and it is best to prepare one or two spare masks.

2. Two hours before the swab test, it is recommended not to eat to avoid vomiting during the test.

3. When waiting for the test, remember to keep a distance of more than one meter between the front and rear personnel to avoid close contact.

4. Whether it is doing swab testing or getting the report, it needs to be certified as one, so be sure to bring ID cards, receipts and other materials, so as to avoid incomplete materials at that time, which will affect the testing and reporting.

What to do before swab test

What to do before swab test

What to do before the swab test?

Why implement full coverage of DNA swab testing?

What should be paid attention to in DNA testing?

The latest statistics on the COVID-19  released by Johns Hopkins University in the United States on the 9th show that the cumulative number of confirmed cases in the United States has exceeded 60 million.

Nucleic acid detection is an effective method for precise prevention and control.

After the COVID infects the human body, it will multiply in the respiratory system.

Using a nasopharyngeal swab to detect sputum can determine whether the human body is infected with the virus, and can quickly and accurately “find out” the virus.

The recent spread of the epidemic has brought new pressure to epidemic prevention and control around the world. There are even reports of a country’s leader being positive for the new crown. Mexican president tests positive for coronavirus. The President of Paraguay has tested positive for the new crown. Poland: President tests positive for coronavirus. Brazil’s president tests positive for coronavirus. etc.

On the basis of continuing to perform nucleic acid testing on key groups of people, close contacts, etc., to identify the infection chain as soon as possible, block the transmission route, control the spread of the epidemic, and implement large-scale full nucleic acid testing, we must achieve early detection, early reporting, Early isolation, early treatment, active search for potential new coronavirus infections, and targeted prevention and control measures are also adopted to protect the health of the masses, ensure the rational flow of the population, and maintain the stable development of social and economic life order. It is very important. significance.

What methods are available for COVID swab testing?

Nucleic acid detection generally adopts the nasopharyngeal swab detection method, including nasopharyngeal swab detection and oropharyngeal swab detection.

At present, most hospitals and institutions in our city use oropharyngeal swabs.

This method is the least painful and more convenient to collect samples.

Is it painful to take a throat swab?

A throat swab is a method of collecting a specimen from the throat area, it is painless, mild nausea or sore throat method, which can be relieved or disappear quickly after collection.

Are DNA tests dangerous to humans?

There is no harm to the human body, only when the throat swab is collected, a slight foreign body sensation will be felt when the cotton swab enters the throat.

What should I pay attention to before and after the inspection?

Before detection

Before the nucleic acid test, it is best not to eat for 2 hours, otherwise, it will cause vomiting.
Do not drink water, smoke, drink, or chew gum 30 minutes before sampling.

Before the examination, reduce the number of swallowing movements, and do not do throat-clearing movements, such as expectoration and spitting.

For example: before the nasopharyngeal swab collection, the subject should provide the collector with the relevant past medical history or related matters.

Such as history of nasal surgery, nasal septum, blood disease, throat disease, or taking anticoagulant drugs.

Be sure to wear a mask before going to the test, take out the mask before the test, and put it on immediately after the test. You can prepare a spare mask, which can be replaced at any time after pollution.

Checking

When collecting oropharyngeal swabs, the subject should tilt his head back, relax as much as possible, take a deep breath, and open his mouth to make an “ah” sound, which will help reveal the throat, but symptoms such as irritating dry cough, nausea and vomiting may occur during this process.

Nasopharyngeal swab During the process of nasopharyngeal swab, symptoms such as swelling, itching, and sneezing may occur, which can be covered with a tissue or elbow.

After detection

Leave the collection site immediately after collection to avoid spitting and vomiting near the collection site.

You must pay attention to hand hygiene before and after the nucleic acid test.

You can wipe your hands with your hands, or you can use hand sanitiser, disposable alcohol, and disinfectant cotton pads.

 

Important reminder:

●Be careful to wear a mask, do not expose your nose and nose, do not take it off at will, or pull the mask to your chin.
●There should be an orderly queue, keep a distance of 1 meter, do not get together, do not gather.
●When waiting in line for a long time, pay attention to sun protection, sun protection, scientific hydration, and a reasonable diet.
● Try to avoid taking public transportation to the nucleic acid test sampling site.

The current situation of epidemic prevention and control is very complicated.
Every day, take care to protect your body.
Wear a mask and follow the epidemic prevention regulations.
Protect yourself and protect others at the same time.
New coronavirus pneumonia cases.
Please accept the general guidelines for prevention and control.
Daily Travel Prevention Control Guidelines.
Take the bus, take the subway.
To minimise contact, payment can be made using a transport card or a mobile app.
Avoid touching public facilities such as seats, armrests, car doors, and armrests with your hands as little as possible. If you do, do not touch your mouth, eyes, and nose directly with your hands, and disinfect your hands in time to avoid contact infection.

Hospitals and other places, after returning home, you should disinfect your outerwear.

How to Swab For Covid Test

How to Swab For Covid Test

How to Swab For Covid Test

Since the outbreak of novel coronavirus pneumonia, we must have experienced nucleic acid testing. Covid swab test Nucleic acid detection plays a very important role in the process of infection diagnosis of COVID-19. It can not only find asymptomatic patients in the incubation period as much as possible but also greatly reduce the risk of infection.

Nucleic acid detection is so important. Next, Dr Li will take you to have an in-depth understanding of the relevant principles of nucleic acid detection, the difference between mixed collection and single collection of nucleic acid detection, and the matters needing attention in nucleic acid detection, to help you better protect yourself while popularizing knowledge.

To understand nucleic acid detection, we must understand the detection principle. Let’s take a look at its detection principle first.

The doctor is testing the patient's nasopharynx swab

The doctor is testing the patient’s nasopharynx swab

What is the principle of nucleic acid detection?

Nucleic acid, the genetic factor of the virus, is a macromolecular chain composed of four nucleotides. Different molecules represent different nucleotides and form a long chain. Nucleic acid detection is through the detection of nucleic acid in the chain, and this segment of nucleic acid is COVID-19 specific, other viruses do not.

Pcr test nasal swab and an antigen test difference for covid 19

Pcr test nasal swab and an antigen test difference for covid 19

The substance detected by the nucleic acid is the nucleic acid of the virus. At present, the detection technology is mainly through PCR (polymerase chain reaction) technology to detect the nucleic acid of the virus. During the detection, the nucleic acid chain of COVID-19 was used as the detection target, and the target gene sequence was amplified by PCR Test, which was combined with a fluorescent labelled probe added in the test reagent to produce a fluorescence signal.

The three forms of nucleic acid detection have their advantages.

Nasal swab test

This test method is to insert the test swab vertically into the nostril. And gently rotate the swab, stay in the nasal cavity for about 15 seconds, to test.

Flocked Tip Swab Nylon Sterile Nasal Swab Stick

Flocked Tip Swab Nylon Sterile Nasal Swab Stick

Compared with throat swabs, nasal swab testing is more accurate for inexperienced testing personnel. And the risk of exposure is lower. However, it is not suitable for some patients with nasal allergies, high blood pressure and people who take anticoagulation and antiplatelet for a long time.

Throat swab test

At present, the most widely used detection method is also a form that is often used by everyone. During the sampling process, the patient opened his mouth and made an “ah” sound, and the testing personnel used a sterilized cotton swab to gently and quickly wipe the pharyngeal lateral wall and posterior pharyngeal wall of the subject many times.

COVID-19 Testing:PCR swab test,antibody test, and antigen test difference

COVID-19 Testing: Throat swab test

Throat swab testing: Often used in the testing process because it is more convenient and fast to collect, and it is more acceptable to the public, but the risk of exposure is also greater.

Anal swab test

This test method is a method of inserting a test swab into the anus and taking a sample at the fold of the anus or taking a sample at 2 to 3 cm for a new coronavirus test.

Many patients reject anal swab testing, but anal swabs can improve the accuracy of testing for new coronavirus infections to a certain extent. Some patients indeed have negative throat swabs, but positive ones are detected by anal swabs. In some patients, the anal swab test was still positive after the other two tests turned negative.

Anal swab

Anal swab

Why do multiple nucleic acid tests need to be performed?

Multiple nucleic acid tests are necessary for epidemic prevention and control.
A negative nucleic acid test does not mean that the tested person is not at risk of infection. Any detection method has the possibility of errors, especially in high-risk areas. To ensure the accuracy of the inspection results and better prevent and control the spread of the epidemic, multiple rounds of inspections must be carried out. There are also the following reasons for taking multiple rounds of detection:

After virus infection, the human body has a certain value-added period. When testing, if the virus in the body does not reach a certain concentration, we may not detect the virus.

When the specimen was collected, due to the different sampling methods, no virus cells were collected. False-negative specimens can also lead to inaccurate collection results.

Errors in the transportation process and storage of samples for inspection will also affect the results of nucleic acid testing.

Therefore, for risk areas and special populations, multiple rounds of nucleic acid testing must be carried out to more accurately and effectively detect the virus source, so as to better and more accurately prevent and control and identify infected people, and cut off the source of the virus. No matter what kind of inspection process, attention must be paid.

Covid-Nucleic-Acid-Test

Covid Nucleic Acid Test Nasopharyngeal Swab Test

This article
To talk to you in detail
Covid nucleic acid test!

But in the face of the “nucleic acid swab test”
This unfamiliar and familiar word
Do you have many questions?

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Do you want to do a nucleic acid test when you go back?

Will it be difficult to make an appointment for nucleic acid testing?

How long does it take to get the results of a nucleic acid test at the hospital?

Should I Swab My Throat or Nose for Rapid COVID-19 Tests?

To answer your questions.
Today.
I’m going to tell you.
Those things about nucleic acid testing.

01. What is nucleic acid detection?

At present, nucleic acid detection is the main method for laboratory diagnosis to determine whether a patient is infected with the new coronavirus. It can achieve early detection, early diagnosis, and early treatment. Real-time fluorescent PCR can be used to detect throat swabs, sputum or blood samples. to covid nucleic acid, or detected by viral next-generation gene sequencing.

simply put

Nucleic acid testing is done by

After collecting human secretions

Tested by the instrument

to see if we have the new coronavirus in our body

If so, the test result is positive

On the contrary, if it doesn’t, it’s negative.

02. How to test the COVID swab?

“Sir, oropharyngeal swab, nasopharyngeal swab, and anal swab, which one to choose?”

How do you do a nasopharyngeal swab?

Nasopharyngeal swabs must be performed with the patient sitting upright with the head in an upright position, as this allows for easy visualization and access to the nasal floor perpendicular to the central axis of the patient’s face.

Flocked Tip Swab Nylon Sterile Nasal Swab Stick

Flocked Tip Swab Nylon Sterile Nasal Swab Stick

Insert the swab into the patient’s nose and align it parallel to the nose and the base of the septum. As long as there is no obstruction in the nasal cavity, the swab continues to move in this direction until it reaches the nasopharynx, at which point the tester feels resistance.

Once the swab reaches the nasopharynx, a gentle rotation and two complete 360-degree rotations are recommended to allow secretions from this area to be absorbed.

Once the swab is removed from the patient’s nose, it is immediately inserted into a viral sample containing a viral transport medium. The handle of the swab extending through the opening of the vial was broken off to allow the tube to be closed.

So
Now that there are oropharyngeal swabs and nasopharyngeal swabs
Why add anal swabs?
To answer your questions
Let’s take a look at their respective advantages and disadvantages

The specific operation of the anal swab is as follows:

Soak a flocked swab in saline, insert it 2-3 cm into the anus, wipe from the folds around the anus, or rotate it gently inside the anus, and insert it into a test tube containing saline.

anal swabs

For fecal swab cultures, all of the above requires the use of sterile equipment and placing the swab in a sterile tube.

So
Now that there are oropharyngeal swabs and nasopharyngeal swabs
Why add anal swabs?
To answer your questions.
Let’s take a look at their respective advantages and disadvantages.

Oropharyngeal swab: relatively simple to operate, less irritating, suitable for large-scale screening. Therefore, the nucleic acid test of oropharyngeal swabs is mainly used in the screening of new coronary pneumonia for the epidemic-related population, which is used in the routine nucleic acid test clinic of the First Affiliated Hospital of NTU.

Nasopharyngeal swab: The technical requirements are high, the human body does not feel comfortable, and the accuracy rate is higher than that of the oropharyngeal swab. However, for some asymptomatic or mildly infected people, the condition recovers quickly after infection, and the pharyngeal nucleic acid may not be detected in 3 to 5 days.

Anal swab: high accuracy, reduce missed diagnosis. The study found that the duration of nucleic acid-positive feces or anal swabs of some infected persons is longer than that of the upper respiratory tract. Therefore, anal swab tests will be carried out for key groups such as isolation points or some imported overseas.

In conclusion.
The three swabs have different lengths.
If you have to test an anal swab.
Don’t be shy.
Whatever the swab,
It is a good swab that can accurately identify the virus.