COVID-19 Pooled Sample Testing:Improve sampling rate and reduce cost

COVID-19 Pooled Sample Testing:Improve sampling rate and reduce cost.

With the advent of autumn and winter, the possibility of a new outbreak of COVID-19  is increasing.

COVID-19’s large-scale community screening is the main means to cope with the recent outbreak of small-scale epidemics at home and abroad.

At present, New Coronavirus’s mixed sample nucleic acid detection has become a routine method to effectively enhance the screening and detection of nucleic acid in community population.

The pooled sample test of covid-19 increase the sampling rate and meet the growing needs of low-risk populations.

Virus transport medium,disposable virus sampling tube

Virus transport medium,disposable virus sampling tube

What is a Pooled Sample Test?

“mixed detection”, that is, nucleic acid test of Pooled Sample.

On the one hand,it is a method to sample several people, such as 3 or 5 or even 10, and then put them into the same virus sampling tube.

On the other hand,pooled Sample means combining the same type of specimen from several people and conducting one NAAT laboratory test on the combined pool of specimens to detect SARS-CoV-2.

What is the significance of nucleic acid test in Pooled Sample?

COVID-19 Pooled Sample Testing Advantages

Because a virus sampling tube only puts one person’s sample, the cost will be very high, and the detection time is long, which is not suitable for large-scale nucleic acid detection.

In principle, the single sample sampling mode is only applicable to high-risk areas and key populations.

In order to improve sampling efficiency, shorten sampling time and reduce sampling cost. Multi Country selection of Pooled sample test scheme.

For example, when 5-in-1 mixed sampling test is used, the result is negative, which means that all five people are negative.

On the contrary, once positive or weak positive is found, it will be traced immediately.

Re collect single tube swabs for review, and then determine which of the 5 people is positive.

Therefore, the cost of 5-in-1 mixed mining is relatively low.

This also caused the 5-in-1 mixed sampling mode to be five times faster than the previous mode of using a virus sampling tube for a human sample.

One of the biggest disadvantages of sample merging is the decrease of associated test sensitivity.

Analyzing multiple samples in a single reaction effectively improves the flux, but it also dilutes a single sample and may reduce the weak positive signal from outside the detection limit.

In short, pooled sample testing is mainly used for large-scale screening to check asymptomatic coronavirus infected persons. It is suitable for large-scale testing projects such as schools, factories, units and urban areas. It has the advantages of efficient screening and resource saving.

Although reduced detection sensitivity is acceptable for screening services in asymptomatic populations.

However, When providing diagnosis for high-risk or symptomatic patients, we must give priority to the accuracy of the results.

The special preservation tube for Pooled Sample test uses medical grade PP as raw material, unique structural design and manufacturing process to prevent liquid leakage. And has the characteristics of high temperature resistance, high pressure resistance and high-speed centrifugation resistance.

Cell medical (Dongguan) Co., Ltd. produces virus sampling tubes of various specifications, both inactivated and non inactivated, disposable virus sampling tubes, pooled sample sampling tubes.
such as 1ml, 2ml, 3ml, 5ml, 10ml and other specifications.

Located in  Guangdong Province, in China,with complete qualifications.

Contact information required.E-mail:flockedswabs@gmail.com

 

Disposable virus sampling medium

Disposable virus sampling media 10ml transport tube for sample collection

Disposable virus sampling media with 10ml transport tube for sample collection.

Product Description

Disposable virus sampling tube

Disposable virus sampling tube

Product name:Disposable virus sampling tube.Keyword:sample collection kit,virus sampling medium.

Function:sample collection,storage,transport virus.

OEM/ODM: accept.

Place of Origin: Guangdong, China.

Disinfecting Type: EO.

 

 

Sampling tube specification

Sampling tube specification

 

Properties: Medical Materials & Accessories.

Tube Volume: 5/10ml.

Stock: yes.

Shelf Life: 12 months.

Material: PP.

Quality Certification: ce,MSDS.

Instrument classification : Class I.

 

Virus DNA / RNA sample preservation solution (inactivated or non)

I believe that my friends must be very curious when they first came into contact with this term. Virus DNA / RNA sample preservation solution, also known as cell preservation solution, virus transport medium or disposable virus sampling tube.

What is a virus transport medium?

First, the virus preservation solution is a liquid that immerses the sampling swab virus sample in the sampling tube and protects the detected substance (DND or RNA) of the virus.

It is mainly used for the collection, preservation and transportation of common virus samples such as New Coronavirus, hfmv, influenza virus and so on.

Researchers can use it to collect throat swabs, nasal swabs, or tissue samples from specific sites.

The samples are stored in a disposable virus sampling tube, which can be used for subsequent clinical experiments such as nucleic acid extraction or purification.

We divide virus transport media into two types, one is non inactivated and the other is inactivated.

The non inactivated type can protect virus protein and nucleic acid, preserve virus activity and facilitate culture and detection.

The inactivated type makes the virus no longer have physiological activity, lose infection and disease, and have fecundity, which can inactivate the virus.

Eliminate secondary infection and protect the safety of transportation and testing personnel.

Because the virus is a parasite, it cannot survive in vitro after sampling. If it cannot be detected in time, it needs to be stored in virus preservation solution.

In order to protect the security of virus detection environment and detection personnel, our virus inactivation preservation solution comes in handy.

Some friends may wonder if the inactivated type will inactivate the virus? How can we check it?

Don’t worry, the purpose of using inactivated preservation solution is to lyse nucleic acid.

Release nucleic acid and then detect nucleic acid through subsequent real-time fluorescent RT-PCR to judge whether the sample contains virus characteristic nucleic acid, that is, whether it is infected with virus.

The virus has a single structure and contains only one nucleic acid and protein. Therefore, the virus is detected when the characteristic nucleic acid is detected.

Then some friends will ask, since the detection is so simple, why do you need virus preservation solution? What role does it play?

Usually, after virus sampling, not all samples can be transported and stored at the sample collection place.

Therefore, we need to transport and retain the collected virus swab, otherwise the virus nucleic acid will degrade quickly and the nucleic acid cannot be detected.

Therefore, we need to add preservation solution to the sampling tube to prevent the virus nucleic acid from being degraded so quickly.

Cell Medical’s virus preservation solution allows viral DNA/RNA to be stored and transported at room temperature for 1 week without degradation.

After extraction using most commercial kits, the obtained DNA/RNA is of high quality and high yield, and can be used for various gene testing and analysis experiments, such as PCR and qPCR, while saving transportation costs.

Cell Medical’s inactivated virus storage fluid uses a small volume storage fluid compared to the large volume storage fluid of a traditional virus sampling tube, which avoids excessive dilution of the collected samples and increases detection sensitivity.

And our inactivated virus storage solution is so easy to use that you can take samples at home.

Moreover, our inactivated virus preservation solution is simple and convenient to operate. You can take samples at home.

Well, if you have anything you don’t understand or want to consult, please leave us a message.

We will have a professional doctor and my little brother will let you answer.

About us

Cell medical (Dongguan) Co., Ltd. is a professional manufacturer and supplier of sampling swabs and virus sampling tubes.

We produce flocked swabs, VTM kits, virus transport media, with multiple automatic production lines.We support custom production, OEM and so on, and develop products with customers.

Welcome to consult us.

Email:flockedswabs@gmail.com.

Disposable virus sampling tube kit

Disposable virus sampling tube kit

Disposable virus sampling tube kit

The virus sampling tube consists of swab + sampling tube + virus preservation solution.

That is, flocked swab, virus sampling tube and virus transport medium.VTM

Why use a disposable virus sampling tube kit?

Virus is a very tiny organism, which is composed of nucleic acid and protein shell. Without its own metabolic mechanism, there is no protease system. Therefore, if the virus leaves the host cell, it cannot continue to survive. Such tiny creatures can bring us many diseases, such as RNA, influenza, HIV and H1N1 viruses. Because it has no cellular structure, the virus itself cannot replicate. Instead, it invades the gene into the host cell and replicates a new virus with the help of the latter’s replication system.

In order to maintain the activity of virus samples and prolong the survival time of virus in samples.

The sampling swab will be stored and transported in the preservation solution.

flocked swab_Disposable virus sampling tube kit

flocked swab_Disposable virus sampling tube kit

Brief introduction

1. In the current COVID-19 epidemic situation, virus sample collection is an important link in virus detection.

2. Disposable virus sampling tube kits can collect, transport, inactivate and store virus samples in specific parts of human body. (not available in the United States).

So what’s the difference between the non inactivated and inactivated virus sampling tubes?

about non inactivated and inactivated virus sampling Virus transport medium

about non inactivated and inactivated virus sampling Virus transport medium

In short, the non inactivated sampling tube can protect the protein nucleic acid of the virus, so that the sampled virus has its originality, better integrity and higher detection rate. In addition to nucleic acid detection, scientists can also use non inactivated samples in other virus research experiments.

Advantages:

★ easy to operate and use

★ add virus stabilizing components to maintain virus activity in a wide temperature range

And reduce the decomposition rate of virus (non inactivated type)

1. Low temperature non freezing storage, does not damage the shell of the virus, and is convenient for long-distance transportation.

2. Applicable to all kinds of swab samples, including oral swab, nasal swab, throat swab, etc.

★ it contains virus lysate and virus nucleic acid preservation solution, which can quickly lyse the virus

Release nucleic acid and stably store nucleic acid (inactivated type)

The inactivated sampling tube contains cleavage salt, which can destroy the protein of the virus. However, it can protect the nucleic acid of the virus, so that the virus has no infectious activity. The sampling virus in the inactivated sampling tube can prevent the risk of secondary infection and ensure the safety of transportation and testing personnel.

note

1. forbidden to directly contact the preservation solution with virus samples.

2. forbidden to infiltrate the swab with preservation solution before sampling.

3. only used for the collection, transportation and preservation of virus samples. It shall not be used beyond the expected purpose.

4. Before using this product, pay attention to the shelf life and whether the packaging is intact.

 

 

 

10 in 1 mixed sample detection virus sampling tube

virus sampling tube 10 in 1 mixed sample detection

10 in 1 mixed sample detection virus sampling tube

Ten in one hybrid collection and detection technology is to collect 10 flocked swab samples collected by 10 people into a collection tube for nucleic acid detection. Once we find positive in the mixed collection screening, we will immediately notify the relevant departments to temporarily isolate 10 subjects in the mixed collection tube. Single tube swabs were collected again for reexamination to determine which of the 10 subjects was positive; If the test result is negative, it means that all ten samples are negative and the mixed ten people are safe.

Mixed detection greatly improves the detection ability of nucleic acid. Using this combination mode, the daily detection ability can be increased by 10 times without increasing human and material resources. It can carry out more screening and early diagnosis, strive to find patients one minute in advance, isolate patients one minute in advance, reduce transmission and save social costs.

Product overview:

① It is applicable to large-scale testing projects such as schools, factories, units and urban areas. It has the advantages of high screening efficiency and resource saving.

② The sampling tube for mixed sample detection of virus uses medical grade PP as raw material. Unique structural design and manufacturing technology prevent night leakage. It has the characteristics of no RNA enzyme, no DNA enzyme, no endotoxin, high temperature resistance, high pressure resistance and high-speed centrifugation.

③ 10ml sample preservation solution (VTM solution) is pre installed in 50ml sampling tube for 10 person mixed sample detection.

 

④ The head end materials of virus sampling swab include flocking, polyester fiber, rayon, etc.Produced by special process, it has no DNA / RNA, no RNA enzyme and no DNA enzyme. It has the characteristics of high collection rate, high release rate, convenient operation and no sundries. The sampling success rate and detection rate are greatly improved.

⑤ Biosafety bag: for preservation and transportation after sample collection to prevent accidental leakage and improve safety.

⑥ Each set of virus sampling tubes includes: 1 sampling tube pre loaded with virus preservation solution, 10 individually packaged swabs。

Instructions for use:

10 in 1 mixed sample detection virus sampling tube

10 in 1 mixed sample detection virus sampling tube Instructions for use

①. Remove the paper and plastic packaging of the swab from the torn place

②. Take the swab to the target part for sampling

③. Immerse the swab head of the sampling swab into the virus preservation solution

④. Break the swab rod

⑤ .at the pharyngeal breaking point. Repeat steps ① ~ ④ for the other 9 sampling times. After collecting 10 swab samples in the sampling tube, tighten the tube cap and shake gently for several times to complete the sampling.

⑥ .immediately place the sampling tube in the biosafety bag, seal and transport it for inspection.