Tag Archives: Oropharyngeal Sampling

COVID-19 Swab Test

COVID-19 Swab Test |One Minute to Learn about Nucleic Acid Test

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COVID-19 Swab Test |One Minute to Learn about Nucleic Acid Test

So far, the number of confirmed cases of the global epidemic has exceeded 237 million, followed by the recurrence of the epidemic. We must do a good job in COVID-19 testing and strive to defeat the virus at an early date.

1. Why a nucleic acid test? What does it test for?

Nucleic acid swab detection is the direct evidence to find the existence of virus. The novel coronavirus pneumonia virus nucleic acid test positive, indicating that the presence of virus in the subjects, may be infectious.

If the patient has fever, respiratory symptoms or other clinical features of NCP, the patient can be diagnosed as NCP when combined with positive nucleic acid test; if there are no clinical symptoms, the nucleic acid test result is positive, can be judged as asymptomatic infection.

Novel coronavirus pneumonia is a diagnostic standard for new crown pneumonia.

2. Nasopharyngeal swab test and oropharyngeal swab test, which test method is better?

As we all know, nucleic acid detection generally adopts pharyngeal swab detection. Pharyngeal swab testing includes nasopharyngeal swab testing and oropharyngeal swab testing. The difference between the two lies in the different sampling positions, but there is no essential difference. Most medical institutions use oropharyngeal swab detection, because this detection method has less discomfort and is more convenient for sample collection.

3 .what are the precautions before and after COVID-19 Swab Test?

Before testing;

Get your ID card ready before you go out!

Wear masks correctly without fasting;

Try to avoid eating in the first 2 hours to avoid vomiting and other discomfort;

Try not to drink water, drink, smoke, drink or chew gum in the first 30 minutes;

When sampling, reduce swallowing action, swallow less saliva and don’t clear throat;

We should inform the testing personnel in advance whether they have a history of nasal surgery, bending of nasal septum, blood diseases, throat diseases or taking anticoagulants;

Before testing, remove the mask after the medical personnel give a signal, wear it immediately after sampling, and prepare a spare mask for easy replacement at any time after pollution.

Testing;

Consciously queue up and keep a distance of more than one meter;

When collecting oropharyngeal swabs, tilt your head back, relax as much as possible, breathe deeply, and open your mouth to make an “ah” sound, which is helpful to complete the sampling quickly;

The nose may be itchy during the collection of nasopharyngeal swabs. If you sneeze, cover your mouth and nose with paper towels or elbows immediately;

During the detection, try not to touch the detection platform and other articles, and do not touch the protective clothing of the collection personnel.

After detection

Leave the site immediately after sampling, and do not spit or throw garbage at the collection point and surrounding areas;

The inspectors shall pay attention to hand hygiene before and after the test. They can wipe their hands with hands-free disinfectant, hands-free alcohol, disinfection cotton, etc.

4 How can nucleic acid detection alleviate the discomfort of sampling?

Nasopharynx swab sampling and oropharyngeal swab sampling will make the sampled person feel slightly uncomfortable, which can be relieved after a short rest. Therefore, during the sampling process, the sampled person shall cooperate with the sampling personnel as much as possible, relax as much as possible, and do not over move the head to avoid scratching the mucosa with the sampling swab.

Flocked Swab Meaning

Flocked Swab Meaning

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Flocked Swab Meaning

This article will introduce what is the flocked swab, the purpose of the flocking swab, the application of the COVID-19 flocked swab and the material of the flocked swab, etc. The flocked swab manufacturer introduces. Give you a comprehensive understanding of flocking swabs.

what is the flocked swab?

Flocked Swab Meaning

Since the outbreak of COVID-19, the word “nasopharyngeal swab” has become a high-frequency word we talk about every day.

In recent months, the new crown pneumonia epidemic broke out again in countries all over the world. It’s worrying to watch the data released by WHO every day!!!

Flocked swab material

The flocked swab is made of nylon fiber flocking technology, and the front end is coated with nylon short fiber fixed vertically so that there is no absorption hole in the sampling area of the whole sampling swab, and the sampling sample will not be dispersed and retained in the fiber, which is conducive to faster and more efficient elution.

Traditional cotton swabs can not completely collect and elute samples while flocking swabs can elute 95% of samples. Therefore, the use of flocking swabs has great advantages for various sample collection applications.

The flocked swab is to deposit nylon fibres on the surface of the medical ABS rod in a certain direction through an electrostatic field to form a brush layer.

What is the purpose of flocked swabs?

Flocking swabs are the best choice for nucleic acid detection because they can better collect cell or biological samples at the collection site and release samples quickly.

Application: forensic medicine, DNA, microorganism, virus sampling, Oral swab, nasal swab etc.

What are flocked swabs used for in COVID-19?

The autumn and winter communication season is a period of the high incidence of common cold and influenza, and the most important means to control the epidemic situation is to select real patients with new crown pneumonia from a large number of respiratory tract patients.

At present, the most effective and widely used new crown sampling methods are nasopharyngeal swab and oropharyngeal swab sampling.

Flocked Swab Meaning _Application of flocking swab in COVID-19

Flocked Swab Meaning _Application of flocking swab in COVID-19

Nasopharyngeal swab collection method.

1. Keep the patient’s head still and remove the secretions on the middle surface of the anterior nostril;

2. Measure the distance from the nose tip to the earlobe with a swab and mark it with your fingers. Insert the swab into the nasal cavity in the direction perpendicular to the nose (face). When encountering resistance, it reaches the posterior nasopharynx, keeps the swab in the nose for 10 ~ 15 s, rotates it gently for 3 ~ 5 times, and take out the test flocked swab.

According to the American Society of Microbiology guidelines for the submission of clinical microbial specimens, the nasopharyngeal swab should be twisted on the nasopharyngeal mucosa, retained for 10-15 seconds, and then removed.

Feeling of nasal flocked swabs sampled by U.S. netizens.

netizens 01

netizens 01

It’s hard, and the tough guy still cries.

I have experienced both sampling methods.

It is not a painful cry, but a stress response caused by strong stimulation of the weak nasopharyngeal mucosa, with tears and tears.

netizens 02

netizens 02

No, as a girl, I don’t feel much about the nose swab sampling, except its excitement went to my head.

netizens 03

netizens 03

The more serious one is like eating mustard oil, and the lighter one is like blowing out your nose for several days.

Our netizens are so cute.

About oropharyngeal swab sampling.

oral swab sampling process_ Flocked Swab Meaning

oral swab sampling process_ Flocked Swab Meaning

Feeling of oral flocked swabs sampled by China's netizens.

Feeling of oral flocked swabs sampled by China’s netizens.

Pharyngeal(oral) swab: the collection process is faster (just a few seconds) and less painful, but you may feel nausea and vomiting, and some people have no obvious reaction.

As we are in the epidemic period, we should improve our awareness of self-protection when doing nucleic acid testing.

Flocked swab manufacturer introduces Cell medical (Dongguan) Co., Ltd.

Cell medical (Dongguan) Co., Ltd. is a comprehensive high-tech biotechnology enterprise.

We have invested a lot of scientific research strength to tackle key technical problems.

At present, our virus preservation tube and flocked swab have shown an irreplaceable role in the detection of new infectious diseases.

We support custom production, OEM and so on, and develop products with customers.

Welcome to leave a message for a consultation!

CONTACT US

Email:flockedswabs@gmail.com

Pcr test nasal swab and an antigen test difference for covid 19

Pcr test nasal swab and an antigen test difference for covid 19

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Pcr test nasal swab and an antigen test difference for covid 19

What is COVID-19?COVID-19 is an epidemic disease caused by SARS-CoV-2. An acute respiratory infectious disease broke out at the end of 2019. So far, WHO has been making the latest tracking report on the new pneumonia on the Internet every day.

What are the current methods of COVID-19 test?

Virus detection includes two types: nucleic acid amplification test (NAAT) (PCR test) and antigen test.

Antibody tests (also known as serological tests) can prove whether you have been infected in the past.

What is the COVID-19 PCR test?

PCR (polymerase chain reaction): similar to the natural replication process of DNA, its specificity depends on oligonucleotide primers complementary to both ends of the target sequence.

Basic principle: the basic principle of PCR technology is similar to the natural replication process of DNA. Its specificity mainly depends on the oligonucleotide primers complementary to both ends of the target sequence. It consists of three basic reaction steps: denaturation, renaturation and extension.

PCR test sample collection method include:

If the sample contains a virus, the researchers will extract its RNA.

Why use the PCR test ?

PCR nucleic acid examination is a direct detection of COVID-19 RNA in human body by sampling from the nasal cavity. The structure of virus is composed of DNA or RNA combined with external lipid protective capsule. Therefore, direct detection of virus DNA itself is the most accurate, fastest and effective new detection method. PCR nucleic acid test can detect infection immediately after the human body obtains the virus, and the accuracy is much higher than antibody test.

ABOUT PCR TEST_Pcr test nasal or Throat swab sampling

ABOUT PCR TEST_Pcr test nasal or Throat swab sampling

How does the PCR test nasal swab work?

Nasopharynx swab is to wipe the secretion of the patient’s nasal cavity or pharynx. And then make the secretion into smear for examination and bacterial culture to clarify what bacterial infection is in the patient’s nasal cavity and pharynx.

Nasal swab sampling procedure

1. Keep the patient’s head still and remove the secretions on the middle surface of the anterior nostril;

2. Gently and slowly insert the swab through the nasal cavity to the nasopharynx;

3. After encountering resistance, it reaches the posterior nasopharynx and stays for several seconds to absorb secretions;

4. Gently rotate and take out the swab and place it in the transport medium;

5. For the swab used for virological test, immerse the swab head into the virus delivery medium, discard the tail, and tighten the tube cover;

If it is necessary to collect from both nostrils, the sampler should use the same swab.

How does the antigen test work?

Rapid antigen detection can play an important role in guiding patient management, public health prevention and control decision-making and covid-19 monitoring.

It is especially valuable for grass-roots areas that may hinder clinical diagnosis and control due to lack of nucleic acid detection capacity or long detection time.

According to WHO, high specificity based on antigen detection indicates that the positive results indicate new crown virus infection.

For patients within 9 days of onset, sampling personnel can use antigen detection as a diagnostic test.

Especially for the staff of medical institutions, inpatients and visitors in the epidemic area.

When nucleic acid detection cannot be effectively implemented, antigen detection can be used as an important screening method.

Rapid antigen test sampling procedure.

Rapid antigen test sampling process

Rapid antigen test sampling process

 

Generally speaking, nucleic acid detection: it has high requirements for laboratory environment, detection personnel and instruments. The detection has high sensitivity and good specificity.Generally, we can get the results in 2-3 hours.

Antigen detection: it has low requirements for the laboratory. For early screening and early diagnosis. It is suitable for large-scale screening in grass-roots hospitals. we can obtain the results within 15 minutes at the fastest.

At present, PCR test nasal swab is widely used, and the sensitivity and specificity of antibody / antigen detection reagents are still limited. 

Each has its own emphasis and cannot replace each other. We should combine multiple virus detection methods.

It can effectively shorten the detection window period and improve the positive detection rate.

 

Respiratory Specimen Collections

Respiratory Specimen Collections

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Respiratory Specimen Collections

Today, with the increasingly severe international COVID-19 epidemic, the correct collection of respiratory samples has become an important prerequisite for ensuring the accuracy of nucleic acid detection results.

However, how to correctly collect respiratory samples? Cell medical (Dongguan) Co., Ltd. summarizes as follows:

Why should respiratory tract samples be collected standardized and correctly?

1. Clear diagnosis;

2. Observe the condition and treatment effect;

3. Guide the formulation of treatment measures;

4. Sample quality directly determines the reliability of test results.

 What are the types of respiratory samples?

1. Upper respiratory tract samples (including swabs, nasal specimens, nasopharynx extracts, pharyngeal gargle and nasal lotion, etc.);

2. Lower respiratory tract samples (such as sputum, tracheal aspirate, lung lotion, etc.);

When is the best time to collect respiratory samples?

Respiratory tract samples were collected as soon as possible after symptoms appeared;

Collect as much as possible within 72 hours of the patient’s fever;

Try to collect before the use of antiviral drugs;

If possible, collect multiple times in multiple days;

What sampling tools are needed to collect respiratory tract samples?

1. Virus sampling kits, including flocked swab, virus sampling tube, virus transport medium, etc;

2. Refrigerated transport box;

3. Personal protective equipment: protective mask (N95), protective glasses.

 How to collect respiratory tract samples?

Oropharyngeal swab sampling process:

Oropharyngeal swab sampling pictures

Oropharyngeal swab sampling pictures

1. The sampler first let the patient sit down, then let the patient tilt his head back and open his mouth.

2. Press the front 2 / 3 of the patient’s tongue with a tongue depressor, and wipe the posterior pharyngeal wall and bilateral tonsils with a nylon flocked swab for 3-5 times to avoid touching the tongue.

3. Take out the rear sampling tube, break the plastic handle at the contact part of the hand, soak the swab into the sampling solution, and tighten the tube cover.

Nasopharyngeal swab:

"nasal

Note : do not use too much force, but try to be as deep as possible, usually more than 5cm, stay for several seconds to absorb secretions, gently rotate and take out the swab, place the sampling tube, break the plastic ellipse at the contact part of the hand, and soak the test piece into the sampling solution, Tighten the pipe cover.

Respiratory Specimen Collections preservation requirements

Those that can be detected within 24 hours can be stored at 4 ℃ and frozen at – 70 ℃ for more than 24 hours.

 

Swab test

Swab test | Disposable virus sampling swab

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Swab test | Disposable virus sampling swab

Disposable virus sampling swab, I believe you are no stranger in the past two years. Because most of the detection tools used for nucleic acid test are disposable sampling swabs. Usually, we see most nasal swabs and pharyngeal swabs. But disposable virus swabs are not only useful for nucleic acid testing. What else can a disposable sampling swab do? Let’s get to know.

What can a disposable virus swab be used for?

In addition to nucleic acid detection, scientists can also use disposable sampling swabs for microbial collection. They are usually used for virus detection and research in hospitals or laboratories. Researchers use disposable sampling swabs to detect biological samples in natural cavities of human or animals. Such as throat, nose, mouth, vagina and so on. It is necessary to collect oral epidermal cells and nasal virus samples with a sampling swab, store the cells and samples in the sampling tube and transfer them to the laboratory for examination.

Oropharyngeal swab sampling

Oropharyngeal swab sampling

Operation (use) method of disposable sampling swab:

Take pharyngeal swab as an example:

① Tear open the packaging bag of the disposable sampling swab and take out the disposable sampling swab from the bag;

Note: please do not let the disposable sampling swab touch the place outside the throat to avoid pollution.

② Put a disposable sampling swab into the mouth and quickly wipe the palatal arch and throat (or lesion) on both sides

③ Take out the swab, put it into the disposable virus sampling tube, break the disposable sampling swab at the broken place and discard the tail;

④ Tighten the sampling tube, put the virus sampling tube into the biosafety bag and submit it for inspection in time.

Note: please do not shake the virus sampling tube excessively to avoid dilution and loss of samples. After sampling, do not touch other objects with a disposable sampling swab.

How to carry out COVID-19  nasal swab test?

The doctor shall wear protective clothing, mask, gloves and mask to let the patient take a proper position.

Gently insert the flocked sampling swab into the nose, rotate it for three times, take it out and put it into the sample tube with protective solution, and screw the cover. Then label it, write the date, and send it to the laboratory for nucleic acid test of nasopharyngeal swab.

 

What is a COVID-19 swab test?

Swab test, namely nucleic acid test. The substance test by nucleic acid is the nucleic acid of virus. Nucleic acid detection is to collect the presence of viruses in the respiratory tract, blood or feces of patients, and determine whether they are infected by COVID-19. Therefore, once detected as nucleic acid “positive”, it can prove that there is a virus in the patient’s body.

SARS-CoV-2 nucleic acid detection process.

The usual sample types include throat swabs, nasal swabs, sputum, bronchoalveolar lavage fluid, alveolar lavage fluid and so on.

The sampling personnel shall conduct PCR detection as soon as possible after obtaining patient samples.

After the testing institution receives the sample, the laboratory personnel shall extract nucleic acid from the sample. And the nucleic acid extraction reagent shall use the nucleic acid extraction kit specified in the approved product manual.

Disposable virus sampling swab material.

At present, because of its stable and reliable performance and excellent absorption and elution capacity, nylon flocked swabs are widely used in COVID-19 sampling.

Swab test result

Swab testing for novel coronavirus pneumonia usually takes 4-6 hours to produce results, while rapid examination takes 2-3 hours. However, the reagents used in each hospital are different, so the time of results is also different.

COVID-19 positive results：Maybe infected.After 24 hours of self isolation, the positive patients need to conduct swab test again.

If the two results are positive, the next step is to improve CRP, blood routine, chest CT and other tests to determine whether COVID-19.

When COVID-19 nucleic acid test is negative once, it should be combined with the clinical symptoms and epidemiological contact history of patients. Because a COVID-19 nucleic acid swab test is negative, it can not completely exclude the infection of COVID-19.

 

flocked swabs definition

flocked swabs definition

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flocked swabs definition

Flocked swab using spray dense planting nylon fiber technology;The volume of samples collected and released is 3 times higher than that of traditional swabs. Ensure the survival rate of cell samples, no residual fatty acids, and will not affect the test results.

Picture of sampling flocking swab

Picture of sampling flocking swab

Why use flocked swabs？

COVID-19 is New Coronavirus’s variant coronavirus, which can cause pneumonia after human infection. It belongs to an acute respiratory infectious disease, which is highly infectious and generally susceptible to people. It is easy to replicate in the upper respiratory tract of human body. In general, new crown nucleic acids are detected rapidly within 96 hours after infection. Testers can find viruses in the human upper respiratory tract. Experiments show that flocking swab can quickly elute > 95% of the original samples, and easily improve the detection sensitivity.

Application of sampling flocked swabs.

The upper respiratory tract of the human body includes the nasal cavity, pharynx and throat. That is to say, if a person is infected with COVID-19, he can extract the nucleic acid of the virus in the nasal cavity, pharynx and larynx in 96 hours. Therefore, we generally sample these locations when we carry out the rapid detection of new crown nucleic acid.

we distinguish swabs by different sampling positions. For nasal sampling, we become nasopharyngeal flocked swabs; For oral sampling, we become oropharyngeal flocked swabs.

What is the difference between nasopharyngeal swabs and oropharyngeal flocked swabs?

Nasopharyngeal swabs and oropharyngeal swabs differ in material hardness in addition to the differences in sampling sites. The nasopharyngeal swab is generally slender and soft, and can change its shape along the nasal cavity, which is convenient for the sampling personnel to probe into the upper respiratory tract along the nasal cavity. The oropharyngeal swab will be thick and hard.

In terms of comfort, there are also great differences between the two. Since gas exchange is often carried out in the nasal cavity, the swab shall be fully extended to the end of the nasal cavity during sampling to ensure that sufficient concentration of samples are collected.  This usually brings very uncomfortable feeling to the subject, and sometimes even leads to epistaxis.The oropharyngeal swab only needs to collect the pharyngeal sample, and only needs the person to open his mouth for collection. Although it occasionally causes a temporary feeling of nausea, the discomfort will not last too long.

There are also obvious differences between the two in drug loading. Studies have shown that in patients infected with the new crown virus, the amount of drug carried on the nasopharyngeal swab is significantly higher than that on the oropharyngeal swab. In other words, the detection amount of nasopharyngeal swabs is generally higher than that of oropharyngeal swabs.

In addition to nasopharyngeal flocked swabs and oropharyngeal swabs, there are anal swabs. As the name suggests, anal swab is a kind of test for patients with gastrointestinal symptoms. It can effectively improve the detection rate, but it is not widely used because of the inconvenience of sampling.

Attention

After sampling the flocking swab, we should immediately put the swab into the storage tube to avoid polluting the sample.  Then, the subsequent rapid detection process of new crown nucleic acid was carried out. No matter what kind of swab is used, the process of rapid detection of new crown nucleic acid is the same.  The rapid detection of new crown nucleic acid was completed in four independent areas of the laboratory, and the test results were obtained.

How to use cm-98000 oral swab

How to use cm-98000 oral swab

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How to use cm-98000 oral swab

Brief description

A large number of clinical experiments on cell medical (Dongguan) Co, Ltd. nylon flocked swab show that CM nylon flocking swab has better collection and transportation effect on clinical microbial samples than ordinary sterile cotton swab. This is especially true for those specimens that cannot be submitted for examination in time and placed for too long.

cm-98000 oral swab

cm-98000 oral swab

advantage

1. The unique jet nylon fiber implantation technology increases the collection and release of specimens.

2. The total length of the swab is 14.5cm, and the plastic rod has a unique breakable design.

3. The villus texture can collect more target analytes.

4. There is no residual specimen, so the specimen processing process can be accelerated.

5. Swabs are sterilized and packaged separately

How to use cm-98000 oral flocked swab

① Tear the sealing paper on the disposable oral swab package, and gently take out the disposable sampling swab from the bag（ Note: the head of disposable oral swab shall not touch other objects other than the inner wall of oral cavity to avoid contamination.)

② . extend the hand-held sampling swab into one side of the oral cavity, from inside to outside at the inner wall mucosa, and then move the swab up and down for 15-20 times. The number can be increased according to the actual situation, with moderate strength. It is appropriate to stick close to the inner wall mucosa of the oral cavity, so as to ensure that the one-time sampling swab head can dip in the exfoliated cells of the oral mucosa everywhere; According to the same method, collect on the other side of the inner wall of the oral cavity.

③ After collection, please take out the disposable sampling swab from the mouth and put it into the sampling tube, push the disposable sampling swab head, put the sampling head into the storage tube, tighten and save it（ Note: too many rotations will lead to dilution or loss of samples. After sampling, make sure that the disposable sampling swab does not touch any other object.)

ABOUT US

Cell medical (Dongguan) Co.,Ltd., a swabs design / swabs manufacturer, has many years of experience in medical application molding and flocking treatment heads and swabs.

Main products:Flocked Swabs,VTM Kits,Viral Transport Medium,VIRUS Collection & Transport Kits,Disposable virus sampling tube,Op swabs,Np swabs,etc.

Contact us

 

how to collect nasopharyngeal swab

how to collect nasopharyngeal swab?

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how to collect nasopharyngeal swab?

After several times of nucleic acid sampling and testing, citizens wondered: why do some people require nasopharynx swabs and some people can collect oropharyngeal swabs?  Today, experts from cell medical will explain to you.

What is a sampling swab?

At present, except for special diseases, COVID-19’s nasopharyngeal swabs and oropharyngeal swabs are the most common ways of collecting.

Studies have shown that nasopharyngeal swabs have higher detection rate of COVID-19 nucleic acids than oropharyngeal swabs. Because the nasopharyngeal cavity is relatively closed and the virus is easier to accumulate. However, whether it is oropharyngeal swab or nasopharyngeal swab, the key is that the collection action must be standardized, in place and meet the standards. As long as the acquisition is standardized, both methods can achieve the expected detection purpose.

How to collect a nasopharyngeal swab?

nasal swab collection method_How to collect a nasopharyngeal swab？

nasal swab collection method_How to collect a nasopharyngeal swab？

1. The patient’s head tilts back (about 70 degrees) and persists. 2. Use a swab to estimate the interval from the ear root to the nostril. 3. Insert from the nostril pen to the face. The deepening interval should be at least half of the length from the earlobe to the tip of the nose. Reach the posterior nasopharynx after encountering resistance, stay for several seconds to absorb secretions (generally 15 ~ 30s), and rotate the swab for 3 ~ 5 times. 4. The swab should be gently rotated and taken out, and the swab head should be immersed in a collection tube containing 2ml lysate or cell preservation solution containing RNase inhibitor. 5. Break the sterile swab rod at the top, discard the tail, tighten the tube cover and close it with sealing film.

oropharyngeal swab collection

collection method of oral swabs

collection method of oral swabs

1. Ask the patient to gargle with normal saline or clear water first.

2. Wet the flocked swab in sterile normal saline.

3. The patient sat down with his head tilted back and his mouth open, accompanied by an “ah” sound.

4. Fix the tongue with a tongue depressor, and the swab jumps over the root of the tongue to the posterior pharyngeal wall, tonsil recess, lateral wall, etc.

5. The bilateral pharyngeal tonsils should be swabbed back and forth with moderate force for at least 3 times, and then the posterior pharyngeal wall should be swabbed for at least 3 times, 3 ~ 5 times.

6. Remove the swab to prevent touching the tongue, pituitary, oral mucosa and saliva.

7. Immerse the swab head into the preservation solution containing 2 ~ 3ml virus.

8. Break the sterile swab rod near the top, discard the tail, tighten the tube cover and close it with sealing film.

After the introduction of our experts, do you have a deeper understanding of sampling swabs? If you want to know more product details and prices, please leave us a message. We will serve you wholeheartedly!

Contact us

    nasal swab test

    Nasal swab test

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    We used pharyngeal swabs to collect samples from nucleic acid samples. They are “nasopharyngeal swab” and “oropharyngeal swab”.

    Nasopharynx swab and oropharyngeal swab only have different sampling paths. Oropharyngeal swab is to collect oropharyngeal specimens by entering the sampling swab through the mouth. And nasopharyngeal swab is to collect nasopharyngeal specimens through the nose.

    Nasopharyngeal swab sampling process

    Nasopharyngeal swab sampling process

    Oropharyngeal flocked swab sampling process

    Oropharyngeal flocked swab sampling process

    The pharynx includes nasopharynx, oropharynx and pharynx, all of which belong to the field of upper respiratory tract.The sampling methods of nasopharyngeal swab and oropharyngeal swab are different.

    PCR test can collect nasopharyngeal swabs, sputum and other lower respiratory tract secretions, blood, feces and other specimens for testing, nucleic acid detection by New Coronavirus.If its specimen nucleic acid is positive, it can clear the virus infection.

    New Coronavirus infection mainly invades bronchial epithelial cells and alveolar epithelial cells. Lower respiratory tract specimens, such as sputum and airway extracts, more accurately reflect virus infection.

    Advantages of nasal swabs

    More specimens can be obtained by staying in the pharynx for a long time, which is also the reason why the positive rate reported in the literature is higher than that of oropharyngeal swabs.

     

    np swab vs op swab

    np swab vs op swab

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    Since the end of July, COVID-19 has been scattered everywhere. Universal COVID-19 nucleic acid detection has been opened in many parts of the world. After several rounds of nucleic acid sampling and testing, many citizens have some doubts. What are the differences between nasopharyngeal test and oropharyngeal swab sampling?

    • What are the ways of sampling the nucleic acid of the SARS-CoV-2?

    nucleic acid samples collected through the nasal cavity are called “nasopharyngeal swabs”. Samples collected through the mouth are called “oropharyngeal swabs”. Both are the main ways to collect samples from COVID-19 nucleic acid detection. In addition, there are deep expectoration fluid, nasopharyngeal or respiratory tract extract, bronchial lavage fluid, and alveolar lavage fluid.

    • how to choose nasopharyngeal swabs and oropharyngeal swabs?

    Whether to choose nasopharyngeal swabs or oropharyngeal swabs, mainly follows the following principles: first, according to the eighth edition of the prevention and control plan and the second edition of COVID-19 nucleic acid testing manual, the first choice is to collect nasopharyngeal swabs while collecting nucleic acid samples. Secondly, asymptomatic infected persons, entry personnel and close contacts should collect nasopharyngeal swabs during isolation observation; Third, due to the relatively simple operation of oropharyngeal swabs, more oropharyngeal swabs should be collected when nucleic acid detection is carried out in low-risk areas.

    • why should nasopharyngeal swabs be collected first?

    The study shows that the detection rate of COVID-19 nucleic acid in nasopharyngeal swabs is higher than that in oropharyngeal swabs, because the nasopharyngeal cavity is relatively closed and the virus is easier to accumulate. Secondly, the sampler can stand behind the patient’s side. The patient only needs to expose his nostrils, and there is basically no pharyngeal reflex. The exposure risk of the sampler is lower and safer than that of the oropharyngeal swab. However, whether it is oropharyngeal swab or nasopharyngeal swab, the key is that the collection action should be standardized, in place and meet the standards. As long as the collection is standardized, both methods can achieve the expected detection purpose.