Tag Archives: Sample collection swab

Sterile Flocked Nylon Swab with 80mm Breakpoint

Sterile Flocked Nylon Swab with 80mm Breakpoint

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Sterile Flocked Nylon Swab with 80mm Breakpoint.

Flocked swabs consist of nylon fibres to provide not only excellent sample collection but also release of that sample into Transport media.

The term “flocked” refers to a process of attaching fibers of variable length flocking to a surface coated in the adhesive in order to enhance sample collection.

Flocked swabs provide advantages for a variety of specimen collection procedures employed by medical and laboratory professionals. The swab is designed to be ergonomic for the user as well as for patient comfort and to optimize sample collection.

The flocked nylon fibers act similar to a fine bristled brush, which creates thousands of contact points whereby, cells, microscopic organisms or particles may be collected. Sterile flocked swabs are the preferred choice when collecting samples from the nasal cavity.

Nasal Swab flocked swab with 80mm breakpoint

Nasal Swab flocked swab with 80mm breakpoint

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Email:flockedswabs@gmail.com

Product parameters.

Nasopharyngeal swab, 80 mm

100 swabs per package

Application type – nasopharynx

sterile

Nylon flocking tip. ABS plastic shaft

Needle tip diameter length: 2.5cm; Width 1 mm; The total length of the swab is 15 cm

Medical Swab Test Kit specimen collection sterile nylon flocked swab

Medical Swab Test Kit specimen collection sterile nylon flocked swab

Sterile Flocked Nylon Swab performance and structure.

Composed of a swab head (flocked nylon plush head) and a polystyrene plastic rod.

Sterile (micro) plastic rod nylon flocked swab (separately packaged) for nasopharynx.

For one-time use and sterilized by radiation.

It is suitable for DNA sampling, nasopharynx and other parts of the sample collection, convenient transmission, avoid pollution.

Name: nylon flocked swab for nasopharynx, plastic rod, aseptic independent packaging.

This product is produced by new technology in Australia. A large number of clinical trials abroad show that compared with ordinary sterile swabs, nylon flocking swabs have better collection and transportation effects on clinical biological samples, especially for those samples that cannot be submitted for inspection in time and placed for too long.

Flocked Nylon Swab Advantage:

1. Connection strength: when the moving speed of the fixture of the tensile testing machine is 200 mm / min; The pull-out force between the sampling head and one end of the connecting rod shall not be less than 2n,

2. Breaking strength: when the test span is 6cm, the swab shall be able to withstand 4N axial static pressure for 15s without permanent deformation or fracture phenomenon.

3. Rotational friction degree: spray nylon fluff on the ABS rod after viscose. The rubbing fastness refers to that the test is not greater than 2n, the rotational friction is not less than 3 times at 360 degrees, and the amount of nylon fluff on the surface is not greater than 2.

The sterile disposable sampling flocked swab has passed the whole project testing by the national quality supervision instrument testing centre, and the qualified test report zc1011965 / 96 / 97 has been issued.

The sampling swabs are divided into pharyngeal swabs, oral swabs, DNA swabs and cervical swabs, which can be used by various laboratory testing centres.

The sampling flocking swab is three times higher than the traditional winding swab in the number of samples collected and released and does not cause damage to the cell sample, so as to ensure the survival rate of the cell sample, no residual fatty acids, no impact on the test and detection effect, and no harm to the human body.

*Nasal swab for medical institutions to collect virus and DNA samples infected in the patient’s nasal cavity;

Sterile Flocked Nylon Swab application

Sterile Flocked Nylon Swab application.

*Type an oral swab for medical institutions to collect virus and DNA samples of patients with oral and throat infections;

oral swab

oral swab.

viral transport medium with swab

Viral Transport Medium with Swab

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viral transport medium with swab | COVID-19 sampling and collection kits

The epidemic has disrupted the whole world and affected many industries.

During the outbreak of  COVID-19, people were paying close attention to the epidemic situation while doing personal protection. Novel coronavirus pneumonia and influenza were the most frequent period of communication in winter and spring. The most important way to control the epidemic is to select new patients with new crown pneumonia from many respiratory patients.

About viral transport medium with swab.

Swabs and virus transport media are a transport and collection system for long-term freezing, transport and collection of clinical specimens containing viruses.

The main species of organisms usually transported through this medium include chlamydia, urea plasma organisms and mycoplasma.

With the outbreak of COVID-19 pandemic, swabs and virus transport mediums were used to freeze and collect SARS-CoV-19 virus samples.

Rub a swab on the skin or vesicles to collect virus samples. The collected samples are then sent to the laboratory with transport media.

Why do swabs need virus transport media？

After virus collection, the traditional method can not be detected by PCR immediately. The virus itself will quickly dissolve in vitro and affect subsequent tests.

viral transport medium with swab -vtm kits

viral transport medium with swab -vtm kits

Purpose of virus transport media:

1. For monitoring and sampling infectious pathogenic microorganisms by disease control departments and clinical departments. It is applicable to the sampling of influenza virus (ordinary influenza, highly pathogenic avian influenza, influenza A H1N1 virus, etc.), hand, foot and mouth virus and other types of viruses.

2.For the sampling of mycoplasma, chlamydia and Ureaplasma.

3.. To transport nasopharyngeal swab samples or tissue samples at specific parts from the sampling site to the detection laboratory for PCR extraction and detection.

4.To preserve nasopharyngeal swab samples or tissue samples at specific sites for necessary cell culture.

Precautions for sample transportation.

1. Inspection time and temperature control:

After samples sampling, for inspection as soon as possible and sent to the laboratory within 2 ~ 4H as far as possible.

Transport at 2 ~ 8 ℃, and the transport time shall not exceed 72h. If it exceeds 72h, stored and transported at – 70 ℃ or lower.

2. Viral transport medium transport container:

Virus transport tube：waterproof, damage proof, leak proof, high temperature (low temperature) and high pressure resistant. 
Tube body: biological hazard signs, warnings and reminders with relevant regulations. 
Transport container: three-layer packaging system, namely inner packaging, middle packaging and outer packaging.

3. Transportation in the hospital:

The specimen delivery personnel shall be provided with secondary protection and carry 75% ethanol with them.

4. Long distance transportation:

The transport package of 2019 ncov specimens belongs to class A, and the corresponding UN number is un2814. The transporter shall wear safety protection according to the requirements of class II protection, and carry 75% ethanol with him. Drivers wear surgical masks or N95 masks and transport them by special vehicles. If transported by air, the packaging shall also comply with the pi602 classified packaging requirements of ICAO document Doc9284-AN / 905 technical rules for safe air transport of dangerous goods. At least one specimen transporter and driver shall transport specimens at the same time, and monitoring facilities for specimen transport process shall be equipped.

Contact us

  • Cell medical (Dongguan) Co., Ltd.
  • skype:+86-18814476009
  • E-mail：flockedswabs@gmail.com
  • No. 98, Wusha street, Chang’an Town, Dongguan City, Guangdong Province, China
  • Web：www.swabmanufacturer.com/

 

COVID-19 Sample Collection and Transport kits

COVID-19 Sample Collection and Transport kits

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COVID-19 Sample Collection and Transport kits

Since the outbreak of the new crown, we have received many customer queries about which types of swabs, media and kits can be used for sample collection and transportation of COVID-19.

Cell medical (Dongguan) Co., Ltd. produce flocked swabs, VTM kits, virus transport medium, with multiple automatic production lines.

We support custom production, OEM and so on, and develop products with customers.

Our flocked swabs are famous for their stable and reliable performance and excellent absorption and elution ability.

Our VTM kits are manufactured in accordance with CDC and FDA guidelines.

Now let’s learn about sample collection and transport kits.

COVID-19 Sample Collection and Transport kits

COVID-19 Sample Collection and Transport kits

How do we collect COVID-19 samples?

Specimen collection requirements

Personal protective equipment (PPE) requirements for sampling personnel: N95 and above protective masks, goggles, one-piece protective clothing, double-layer latex gloves and waterproof boots; In case of contact with the patient’s blood, body fluids, secretions or excreta, replace the outer latex gloves in time.

Specimen type

1. Upper respiratory tract specimens: including pharyngeal swab, nasal swab, nasopharyngeal extract, etc.

2. Lower respiratory tract specimens

3. Stool samples: Patients with diarrhea symptoms need to collect stool samples.

Specimen collection method

Sampling flocked swab_Sample Collection

Sampling flocked swab_Sample Collection

1. Pharyngeal swab: wipe bilateral pharyngeal tonsils and posterior pharyngeal wall with 2 plastic rod swabs planted with pile at the same time, immerse the swab head into a tube containing 3ml virus preservation solution (isotonic salt solution, tissue culture solution or phosphate buffer can also be used), discard the tail, and tighten the tube cover.

2. Nasal swab: gently insert a plastic rod swab with a flocking nylon faucet into the nasopalatine part of the nasal canal, stay for a moment, and then slowly rotate and exit. Take another plastic rod swab with polypropylene fiber head and collect the other nostril in the same way. Immerse the above two swabs into the same tube containing 3ml sampling solution, discard the tail, and tighten the tube cover.

What kind of Media do you use to transport specimens?

Since the outbreak of COVID-19, the Virus Transport Medium has played a major role. Sample and nasal swabs are used to protect samples in the sample tube with virus preservation, which improves the accuracy of detection. Virus preservation solution is a solution for virus sampling, preservation and detection. What kinds of virus preservation solution are added to the virus sampling tube?

virus transport medium

virus transport medium

There are two types of virus preservation transport Media: inactivated and non inactivated.

The following briefly introduces several principles for the selection of virus preservation solution.

Non inactivated virus transport medium:

The non inactivated type does not contain lysate.

On the basis of Hank’s, BSA (bovine serum albumin) amino acids, vitamins and other nutrients required by the virus are added, which can maintain the activity of the virus in a wide temperature range and maintain the originality of the sample to the greatest extent.

For nucleic acid extraction and detection of the virus, virus culture and separation.

Characteristics of non inactivated preservation solution:

COVID-19 Sample Collection and Transport kits Use process

COVID-19 Sample Collection and Transport kits Use process

1. It can maintain virus activity for detection or virus isolation;

2. It has no inhibitory effect on subsequent nucleic acid amplification;

3. stored in cold storage(at 2 ℃ ~ 8 ℃ ).

Inactivation virus transport medium:

Inactivation preservation solution can inactivate the virus in the sample by fully mixing the collected sample with virus lysate and virus nucleic acid preservation solution, and effectively ensure the integrity of virus nucleic acid in the sample.

About the preserved viral RNA samples: used in gene detection, enzyme-linked immunosorbent assay (ELISA), PCR detection and so on.

Inactivation preservation solution includes guanidine salt containing and guanidine salt free.

1. Guanidine salt

(1) Instantly cleaved and inactivated to reduce the risk of sampling;

(2) Stored stably at room temperature for 2 weeks;

(3) It can match most nucleic acid extraction reagents.

2. Non refined salt

(1) Inactivated instantaneously to reduce the virus sampling risk, and the virus may recover its infectivity after dilution;

(2) Stored stably at room temperature for 2 weeks;

(3) It can match most nucleic acid extraction reagents.

3. Direct expansion preservation solution

(1)Inactivated instantaneously to reduce the virus sampling risk, and the virus may recover its infectivity after dilution;

(2)Stored stably in cold storage for 24-48 hours;

(3) Directly added to the nucleic acid amplification system as a template;

(4) Match most nucleic acid extraction reagents and nucleic acid release agents.

 

What is a Nasopharyngeal Swab?

What is a Nasopharyngeal Swab?

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What is a Nasopharyngeal Swab?

COVID-19 Nucleic acid swab test  is a very effective and effective measure to prevent and control the new crown pneumonia epidemic.

The upper respiratory tract of human body includes nasal cavity, pharynx and throat.

That is to say, if people are infected with COVID-19, they can extract the nucleic acid of the virus in the nasal cavity, pharynx and larynx in 96 hours.

Therefore, we usually sample these locations in the rapid detection of new crown nucleic acids.

How to collect a nasopharyngeal swab?

Nasal swab sampling process

The first step is to collect secretions.

First, the medical staff will use a pharyngeal swab to wipe the subject’s nasal cavity or throat tonsils to collect salivary secretions.

nasal swab collection method

nasal swab collection method

The second step is to reserve samples.

After collecting the sample, immerse the nasopharyngeal swab in the preservation solution and screw on the tube cover to retain the sample.

The third step is to send samples for inspection.

Then, put the samples into clean sealed bags and send them to relevant parts for testing.

The fourth step is nucleic acid extraction.

Relevant departments will send the samples to the designated laboratory for nucleic acid extraction experiment.

Step 5: fluorescent PCR nasopharyngeal swab.

After collecting nasal samples, the experimenter uses fluorescent PCR to detect whether there is amplification reaction.

That is, to judge whether it is negative or positive.

Step 6:Finally, Receive test report.

Finally, according to the fluorescent PCR reaction results of nucleic acid detection, the nucleic acid detection vehicle inspection report is obtained, and I can query the results.

Sampling swab material

The sampling swab used for nasopharynx collection consists of a narrow rod made of a short plastic rod, one end of which is covered with an absorbent material. Such as cotton, polyester or flocked nylon.

The swab used for virus sampling should directly contact the sampling part.

The material of the sampling head is closely related to subsequent detection.

And the material requirements of virus sampling swab will be very high.

The virus sampling swab head shall be made of polyester (PE) synthetic fiber or artificial fiber.

Forbidden to use calcium alginate sponge or wooden swab (including bamboo stick).

However, calcium alginate and wood components can also absorb proteins after immersion in the preservation solution, and even inhibit the subsequent PCR reaction.

What are the advantages of using flocked sampling Nasopharyngeal swabs?

1. Flocked swabs provide better sampling.

Flocking swabs are a good choice for rapid diagnostic tests because they can better collect cells or organisms at the collection site and ensure the rapid release of the whole cell.

2. Enhanced diagnostic sensitivity.

Professional flocked technology turns each fiber into a velvet like swab, thus creating hundreds of thousands of contact points to better collect and release the collected samples.

Compared with non aggregated swabs, the increase in the number of target cells helps to improve the sensitivity of rapid diagnostic tests.

3. Rapid elution.

Their stable and reliable performance and excellent absorption and elution ability.

4. Easy handling and transportation.

sterilized and packaged separately, and the sterile swabs.

 

 

 

Saliva Sample Collection Kit :Disposable saliva DNA RNA sampling tube

Saliva Sample Collection Kit :Disposable saliva DNA RNA sampling tube

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Saliva Sample Collection Kit :Disposable saliva DNA RNA sampling tube.

Non-invasive ! No blood, No needle.

No risk of infection, no need accompany of Doctor, no need refrigerate.

people can collection their Saliva sample at home and mail to Lab for DNA test.

what are the differences between the nasal swab and saliva tests for covid 19?

What is saliva collection kit?

In recent years, with the development of medicine, the examination technology has become more and more high-end. And the examination items have become more and more accurate.

Saliva is a complex mixture, which not only contains various proteins. It also contains DNA, RNA, fatty acids and various microorganisms. Therefore, it is possible to diagnose diseases by detecting saliva. Gene detection and analysis.

Saliva collector plays an important role in the process of collecting, transporting and storing saliva samples.

It is noninvasive and easy to self-management, and reduces the risk of medical staff exposure.

Saliva Collection Kit suitable for SARS-CoV-2 sample collection.

Nucleic acid detection is the most widely used new crown detection method.

Including PCR nasopharynx swab, oropharyngeal swab  and saliva sample test.

High precision. As long as the collection, breeding and separation of nucleic acids are successful, there is basically no false positive or false negative.

But the sampling staff are easy to be exposed and the risk is high; With one more step of extracting nucleic acid, unskilled technicians are likely to fail to extract, resulting in false negative, or pollute with other people's samples, resulting in false positive.

 

How to use saliva sample collection kit

saliva process 01

 

1.Before collecting saliva,relax your cheeks andgently massage cheeks with fingers for 15~30 seconds to produce saliva. Gently

2mL  saliva into thefunnel until the liquid saliva(non-bubble)reaches the height of 2.0 ml scale line. Saliva samples collected shall be free of impurities and sputum.Don't spit all over the vial.

saliva process 02

 

2.Hold the Hold the storage vial in hand and keep it upright, then insert the bottom of storage vial into the saliva collection cup, and screw down. Then the storage liquid in the vial will flow into the saliva collection vial.

Saliva Sample Collection sampling process 03

 

3.Keep the collecting vial upright, unscrew the funnel, take out the clean saliva collecting vial cap from the packing box,screw and tightenit on the saliva collecting vial. The vial caps have a chok-ing hazard. Keep out of reach of children.

Saliva process 03

 

4.Shaking Turn the collecting vial upside down for 10 times to fully mix saliva ten times and preservation solution.

Saliva process 05

 

5.Take out a bar code from the packing box and stick it on the saliva collecting vial, then put the collecting vial with bar code and two bar codes into the sample bag for storage, transportion or testing, and the remaining bar code is kept by the user for subsequent information feedback.

Mini flocked nose swab china factory and manufacturers

Mini flocked nose swab china factory and manufacturers

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Mini flocked nose swab china factory and manufacturersCell medical (Dongguan) Co., Ltd.,  flocked swab adopts vertical nylon fiber, which has stable and reliable performance and good adsorption and elution ability. Flocked swabs optimize sample collection and elution into the transmission medium. The swab also has a molded breakpoint that allows you to safely and easily disconnect the cotton swab. Our company provides multiple breakpoint options for different pipes.We can customize swab mold, swab packaging, sterile packaging and swab OEM services.

Mini flocked nose swab Specifications

Mini flocked nasal swab

Mini flocked nasal swab

 

  • Swab Length: 145mm±5mm
  • Flocked Tip Length: 8mm
  • Swab Tip Diameter: 8mm±0.2mm
  • Breakpoint: 80/90mm
  • Packing: Individual Sterile Package
  • Certificate: CE/FDA/ISO
  • OEM/ODM: Support
  • GMP Factory: YES
  • Supplying Ability: 500,0000pcs/ day

 

Application: Nasopharyngeal Sampling Swab

Mateiral: 100% Medical Grade Nylon

Sterilization: EO

Certificate: ISO13485, CE, FDA, SGS, MSDS, TDS.

What’s the use of a flocked nose swab？

Nasal swab detection is a kind of nucleic acid detection, which is used to detect the presence of viral nucleic acid in the body. So as to determine whether the human body infected with COVID-19.

Nasal swab detection requires collecting cells deep in the throat of the tested person and placing them in a Petri dish for observation. Because New Coronavirus is mainly transmitted through the respiratory tract,if the human body is infected with COVID-19, there will be a lot of viruses in the throat. Therefore, it is a more accurate way to detect the existence of COVID-19 by detecting the cells in the throat.

What is the method of mini nasal swab collection?

① Please keep the patient’s head still and remove the secretions on the surface of the anterior nostril;

② use a flocked swab or other tools to the distance from the nostril to the root of the ear and mark it with your fingers;

③ insert the swab gently and slowly through the nasal cavity;

④ swab until the finger mark or stay for several seconds after encountering resistance to absorb secretions; (generally stay for 15-30 seconds, and then rotate gently for 3 times);

⑤ gently rotate the swab and put it into the virus sampling tube (transport medium); Break the swab tail rod along the breaking point and place it completely in the tube. Tighten the pipe cover.

⑥ If you need to collect from two nostrils, you should use another swab.

⑦ Send to the inspection room for inspection as soon as possible.

⑧ Note the information of the collected person to avoid confusion.

Mini flocked nasal swab sampling display

Mini flocked nasal swab sampling display

China Sterile Sampling Swab

China Sterile Sampling Swab factory and manufacturers

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China Disposable Sterile Sampling Swab factory and manufacturers

Guangdong Dongguan city Changan town comprehensive high-tech biotechnology company -Cell medical (Dongguan) Co., Ltd. , Nissan large amount of flocking sampling swab, Disposable Sterile Sampling Swab help COVID-19 prevention and control.

Our GMP factory _Cell medical (Dongguan) Co., Ltd.

Our GMP factory _Cell medical (Dongguan) Co., Ltd.

Controlled environment Labor uniform strict control, Ensure DNA& RNA free product

Controlled environment Labor uniform strict control, Ensure DNA& RNA free product

 

Brief description

China Sterile Sampling Swab floced swab

China Sterile Sampling Swab floced swab

Aseptic environment sampling swabs include aseptic environment sampling swabs, disposable sampling swabs, aseptic sampling swabs, disposable aseptic environment sampling swabs and disposable aseptic sampling swabs.

sterilization and packaging method

1. Sterilize the product with ethylene oxide

2. Adopted international paper plastic packaging convenient for sterilization.

3. Independent packaging, easy to use.

special storage conditions and methods

Stored in a cool, dry and clean environment with no corrosive gas at 2 ℃ ~ 30 ℃ and relative humidity of 40% ~ 90%.

Nasal swab: for medical institutions to collect virus and DNA samples infected in patients’ nasal cavity. Virus sampling swab: used for nose and throat sampling of respiratory and intestinal viruses such as influenza, swine influenza, avian influenza, hand, foot and mouth.

Product composition: ⑴ nylon flocked swab. That is, sterile sampling swab (for sampling, the release is up to more than 90%).

 Product features:

① International paper plastic packaging convenient for sterilization.

② γ Ray sterilization to ensure sterility.

③ Each set of independent packing in the large packing box is convenient to use.

④Researchers can select different culture media (bacteria, viruses, mycoplasma, chlamydia) for different types of specimens.

China Sterile Sampling Swab (Cell medical ) advantages:

1. Collection swab features: the collection system adopts nylon flocked swab, which is non-toxic to microorganisms and can maximize the collection and release of samples.

2. A large number of clinical experiments show that compared with ordinary sterile cotton swabs, nylon flocked swabs have a better effect on the collection and transportation of clinical microbial samples.

Especially for those samples that cannot be submitted for examination in time and placed for too long.

Advantages of flocked swabs:

① The unique jet nylon fiber implantation technology increases the collection and release of specimens.

② The total length of the swab is 15cm, and the plastic rod has a unique breakable design.

③ Flocking swabs can collect more target analytes.

④ There is no residual specimen, so the specimen processing process can be accelerated.

⑤ Swabs are sterilized and packaged separately. Aseptic swabs packaged separately.

Comparison of advantages of various testing methods of COVID-19

Comparison of advantages of various testing methods of COVID-19

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advantages of various testing methods

The detection methods of COVID-19 mainly include nucleic acid detection, antibody detection and antigen detection. Due to the low detection rate of antigen, the SARS-CoV-2 detection mainly focuses on antibody and nucleic acid detection. Nucleic acid detection has the characteristics of early diagnosis, high sensitivity and specificity; However, antibody detection is convenient and rapid, which can be used as a supplementary means of nucleic acid diagnosis. Due to the limitations of “false positive” and “false negative” antibody detection, it is not suitable for general population screening such as returning to work,  and school, nor for epidemiological investigation in low epidemic areas.

NAT Detection process

The detection procedure needs to go through five steps: sampling, sample retention, preservation, nucleic acid extraction and computer detection.

First, collect samples according to the instructions of the kit. The sample types include pharyngeal swab, nasal swab, sputum, bronchial lavage fluid, alveolar lavage fluid, etc.

Because RNA is easy to degrade, flocked swabs without RNase and storage tubes without RNase are used when collecting samples.

After obtaining the patient’s sample, it needs to be tested as soon as possible. If it cannot be tested immediately, it needs to be packaged at low temperature and sent to a special testing institution for testing.

After receiving the sample, the testing institution shall extract the nucleic acid from the sample. The nucleic acid extraction reagent shall use the nucleic acid extraction kit specified in the approved product manual.

Finally, fluorescence PCR nucleic acid detection, that is, machine detection. It takes 70-80 minutes to amplify the extract by fluorescence PCR.

Sample collection, oropharyngeal swab or nasopharyngeal swab

Sample collection, oropharyngeal swab or nasopharyngeal swab

NAT Detection process Nucleic Acid Testing

NAT Detection process Nucleic Acid Testing

Antibody detection

After the virus invades the human body, the human body will produce corresponding specific antibodies for defense.

According to different molecular structures and antigen specificity, scientists divide immunoglobulins into five categories: IgG, IgA, IgM, IgD and IgE.

After the antigen enters the human body for the first time, plasma cells secrete antibodies after a certain incubation period. IgM first appeared, but the antibody had short maintenance time, low concentration and low affinity. It lasted for several days to several weeks in the blood. It was a diagnostic index of acute infection; When IgM is about to disappear, the content of IgG reaches the peak. IgG appeared late, but its concentration was high, its maintenance time was long and its affinity was high. The positive serum IgG indicates the middle and late stage of infection or previous infection.  But the antibody content increases rapidly in the short term, which may be several times to dozens of times higher than the original antibody content. It is mainly IgG, which lasts a long time in the body, and IgM rarely increases.

In this epidemic, the researchers studied patients with covid-19 and found that after the virus invades the human body, IgM antibody takes about 5-7 days to produce and IgG antibody takes 10-15 days to produce.

Antibody detection kits-advantages of various testing methods

Antibody detection kits-advantages of various testing methods

Comparison of advantages and disadvantages of two different detection methods

Compared with the serological detection of antibodies, Nucleic Acid Testing can detect patients in the window stage.

Early detection of infected persons is the “gold standard” for COVID-19 detection, but it requires higher detection equipment or platform.

The high sensitivity RT-PCR instrument is expensive, and the laboratory cleanliness and operator requirements are higher. In addition, nucleic acid detection takes a long time. Considering the sample transportation and sample backlog, the results can be reported as soon as 24 hours.

Compared with nucleic acid detection, blood samples detected by antibody serology are easier to obtain. If the RNA of the virus detected by nucleic acid is the direct evidence of the existence of the virus, the antibody detection is the antibody stimulated in the patient’s blood, which is indirect evidence and has a suggestive effect on the clinic.

When nucleic acid detection is negative, adding IgM and IgG antibody detection can make up for the shortcoming that nucleic acid detection is easy to cause missed diagnosis.

About us

Cell medical (Dongguan) Co., Ltd., a professional VTM kits and swabs manufacturer, has many years of experience in medical application molding and flocked treatment heads and swabs.

Our flocked swabs are famous for their stable and reliable performance and excellent absorption and elution ability.Certificate:FDA,CE,EU,Free Sale,Export license based on (GMP).

We produce flocked swabs, VTM kits, Virus transport medium, with multiple automatic production lines.We support custom production, OEM and so on, and develop products with customers.

  • E-mail：flockedswabs@gmail.com

     

    Iclean nylon flocked swab

    Iclean nylon flocked swab

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    Iclean nylon flocked swab

    Product purpose:

    Iclean nylon flocked swab is ideal for bacteriological sample processing, virological cell culture, DFA test, rapid and direct test, enzyme immunoassay test, polymerase chain reaction and molecular diagnosis based test, as well as forensic identification.

    For throat sampling of respiratory viruses such as influenza, swine influenza, avian influenza, hand, foot and mouth.

    Iclean nylon flocked swab,View more

    Iclean nylon flocked swab,View more

    Characteristics of sampling swab products:

    1. It has extraordinary water absorption capacity, which can increase the number of samples collected on its surface from 20% of traditional sampling swabs to 60%.

    2. The release rate of the collected samples is more than 90%, so as to ensure the high reliability of the results.

    3. Different preservation solutions were selected for different specimen types.

    4. The plastic rod has a unique breakable design to facilitate specimen transportation.

    5. Ethylene oxide sterilization, irradiation sterilization, independent packaging.

    Iclean gene sampling series flocking DNA oral test pieces are specially used to improve the amount and quality of genomic DNA in oral test piece cells. Oral cell sample is a good non-invasive collection and detection method instead of blood. Combined with icleanhcy’s series of DNA separation and stabilization kits, it can quickly collect high-purity and complete DNA samples.

    DNA flocking swab is suitable for human and animal use. It has advantages over other DNA samples in design. Its unique sample matrix and rapid release interface are more conducive to efficient cell collection and maximize DNA yield. The test piece has been sterilized with ethylene oxide and passed the detection of human DNA contamination.

    characteristic

    The unique test substrate greatly improves the yield of DNA;

    Adult oral SWAB piece 1 to 10 μ g DNA;

    It is a good alternative to blood collection;

    Both human and animal can use it;

    Simple and fast operation;

    There are two types of single and double disinfection packaging to choose from;

    application;

    Genotype study;

    Veterinary genotyping and diagnosis;

    Parent child and genetic services;

    Forensic and DNA population studies;

    About us

    Cell medical (Dongguan) Co., Ltd. produce flocked swabs, VTM kits, virus transport medium, with multiple automatic production lines.We support custom production, OEM and so on, and develop products with customers.

    Email:flockedswabs@gmail.com

    Sample collection swab :How much do you know about nucleic acid testing

    Sample collection swab :How much do you know about nucleic acid testing

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    Sample collection swab:How much do you know about nucleic acid testing

    The spread of the covid-19  is continuing worldwide. Although the global scientific and medical circles are making every effort to fight the epidemic, it is difficult to predict how the epidemic will develop in the future, and its impact on social development has appeared in many aspects.

    Currently, COVID-19 cases are over 220 million.

    Currently, COVID-19 cases are over 220 million.

    In order to fully control covid-19, the general screening of local areas shall be carried out if necessary.

    After identifying the detection object, how to detect it?

    1、 What specimen to choose?

    According to the recommendations of the American infectious diseases association, the following specimens were used:

    The sensitivity of simple oropharyngeal swab may not be enough, so it is relatively easy to miss diagnosis.

    The sensitivity of alveolar lavage fluid is the highest, but it is obviously not suitable for universal screening.

    Nasopharynx swabs and other operations should also be standardized.

    Improper operation may make the quality of collected samples not high, thus increasing the risk of missed diagnosis.

    2、 Select the time of detection

    It is very important for COVID-19 to measure RNA and choose the right time. One analysis included 7 studies, including 2 unpublished reports, to evaluate the detection efficiency of RT-PCR at different time points after exposure to virus :

    On the day of exposure to the virus, the possibility of detecting viral RNA is almost zero;

    On the fifth day after exposure, that is, the first day after infection, the detection probability was 62%

    About the 8th day after exposure, i.e. the 4th day after infection, the probability of detection was 80%

    On the 21st day after exposure, i.e. the 17th day after infection, the detection probability was 34%

    In conclusion, exposure to COVID-19 may require multiple tests to avoid missed diagnosis. However, it is not recommended to repeat the test within 24 hours of the previous test; The interval between two tests shall be at least 24 hours.

    After 28 days of exposure to the virus, if the infection has not been diagnosed, it is not necessary to continue the detection; At this time, it is almost certain that it is not infected.

    Nucleic acid detection throat swab  sampling process

    The COVID-19 nucleic acid was novel coronavirus, which was collected from sputum or lower respiratory tract by real-time fluorescent RT-PCR. If positive, the new coronavirus could be diagnosed. This is the basis for the diagnosis of new type of pneumonia. In addition to detecting the nucleic acid of the virus, it can also detect whether the virus in the specimen is highly homologous with New Coronavirus. If so, it can be diagnosed as New Coronavirus pneumonia. The virus is highly infectious and has the characteristics of human to human transmission, but the virus is sensitive to temperature and sunlight and ultraviolet rays.

    Sample collection, nasopharyngeal swab sampling

    Sample collection, nasopharyngeal swab sampling

    Sample collection, Oropharyngeal swab sampling

    Sample collection, Oropharyngeal swab sampling

    The flocked swab is the best raw material for sampling swabs.

     

     

    reference

    1，Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19, updated December 23, 2020. https://www.idsociety.org/practice-guideline/covid-19-guideline-diagnostics/ (Accessed on January 14, 2021).

    2，Kucirka LM, Lauer SA, Laeyendecker O, et al. Variation in False-Negative Rate of Reverse Transcriptase Polymerase Chain Reaction-Based SARS-CoV-2 Tests by Time Since Exposure. Ann Intern Med 2020; 173:262.