Combined Throat And Nose Swab

Combined Throat And Nose Swab

What is the difference between a nasal (Nose) swab and a throat swab for nucleic acid testing

The sampling method and location are different. The accuracy rates of the nucleic acid test ( PCR Test ) nasal swabs and throat swabs are usually similar, and the main difference lies in the sampling method and sampling site. For nasal swabs, nasopharyngeal swabs (flocking swabs) are mainly used to test the secretions from the inside of the nasal cavity and the surface of the nasal mucosa through the nasal cavity;

Throat swabs: Health care workers collect samples in the mouth with oropharyngeal swabs. Health care workers take throat samples for testing to determine whether a patient has the new coronavirus.

Are both throat swabs and nasal(Nose) swabs required?

Let’s talk about throat swabs first.
The “oral sampling” and “nasal sampling” mentioned above are actually test methods in which medical staff use medical swabs to collect samples from the pharynx in nucleic acid testing (PCR).

COVID-19: Will The Pandemic End in 2022?

It is very important to continue swab testing while the pandemic is still ongoing

Whether entering from the nasal cavity or the mouth, the specimens we need to collect are pharyngeal secretions, including sputum. Compared with the oral route, nasal sampling can provide better safety protection for the sampling person. Because oral sampling requires subjects to open their mouths wide, this increases the risk of virus transmission by droplets. However, if it is collected through the nasal cavity, the environment is relatively stable, and the medical staff who operate it will be safer.

What is the difference between a throat swab and a nasopharyngeal swab, which is more accurate?

The main difference between nasal swabs and throat swabs lies in the location and material of the specimens, which are usually as accurate. The throat swab is in the pharynx, and the nasal swab needs to go into the nasal cavity, not the external nasal cavity. It needs to use a longer swab and slowly rotate it to the deep part of the nasal cavity, so the parts of the material are different. Nasal swabs are special, and the material is relatively soft, which is convenient for reaching the deep nasal cavity through the nasal cavity. The process of taking it may take longer than that of throat swabs.

Compared with nasopharyngeal swabs, oropharyngeal swab sampling is sometimes difficult to meet the normative sampling requirements due to irritating reactions, and the actions of eating, drinking and swallowing will reduce the oropharyngeal to a certain extent. The virus enrichment of 2000 may affect the positive detection rate of oropharyngeal swabs.

Which is better, nasal(Nose) swab or throat swab?

No matter which one is adopted, the key lies in the depth of the collection, whether the collection is in place and the length of contact time with the deep mucosa. 

 From the personal experience of the testing population, throat swabs will be less irritating and uncomfortable than nasal swabs.

Flocked Sterile Swabs

Sterile Flocked Swab

Oropharyngeal swab

  • The operation is relatively simple and less irritating, suitable for large-scale screening.

  • The sampling staff will guide the subject to open the mouth, and then use a sterile long cotton swab to gently scrape the subject’s throat to collect secretions from both palatine arches, pharynx, and tonsils.

Nasopharyngeal swab

  • The technical requirements are high, the human body does not feel very comfortable, and the accuracy is higher than that of oropharyngeal swabs. For key groups such as isolation points.

  • The sampling staff will insert a long sterile cotton swab into the nostril of the subject, and reach the mucous membrane deep in the nasopharyngeal cavity, stay for a few seconds to soak the secretion, and then take it out.

Who is not suitable for nasal swab

What is A Covid-19 NP Swab?

What is A Covid-19 NP Swab?

When collecting nasal swab specimens, the flocked swab ( learn more ) will enter the nasal cavity.  

f the medical staff operates in a standardized manner, it will reduce the irritation to the mucous membranes.

But because we can’t see the sampling position of the pharynx.

It mainly relies on the hands of medical staff to feel the resistance, so the technical requirements of the operator are very high, and the tools used are also more complicated.
The improper
 operation will cause certain irritation to the nasal mucosa, so it is not recommended for patients with sinusitis and allergic rhinitis to do nasal swabs to avoid damage to the nasal cavity.

How to overcome the discomfort of throat swab

When collecting throat swab specimens, the oropharyngeal flocked swab will cause certain irritation to the pharynx. For some people with the sensitive pharynx, nausea and vomiting may occur.

Recommended to relax before collecting specimens.

Don’t get too nervous. If you feel discomfort in your throat after collection, you need to eat less spicy, irritating and greasy food, drink more water, eat more vegetables and fruits, and arrange rest appropriately. Generally speaking, it does not take long to return to normal.

Experts said that the study found that the nucleic acid-positive duration of feces or anal swabs of some infected people is longer than that of the upper respiratory tract. Increasing anal swab sampling can improve the detection rate and reduce missed diagnosis; but anal swab sampling is not convenient enough, and currently only for isolation. Points and other key groups to use.

 

Flocked Swab With Vtm Kits Leading China Manufacturer

Flocked Swab With Vtm Kits Leading China Manufacturer

What are flocked swabs used for?

Flocked swabs are widely used in Covid Test bacteriological sample processing, virological cell culture, DFA testing, rapid and direct testing, enzyme immunoassay testing, polymerase chain reaction and molecular diagnostic-based tests, and forensic identification. Both are ideal.

For throat sampling of respiratory viruses such as influenza, swine flu, bird flu, hand, foot and mouth.

Vtm Kits are used for the collection, transportation and storage of influenza, avian influenza, coronavirus and other virus samples for subsequent extraction and PCR amplification.

After samplers collect virus samples, they usually do not conduct PCR testing at the sample collection site in time.
So the collected virus flocking swab samples need to be transported. The virus itself will rapidly decompose in vitro, affecting subsequent detection. During transport, we need to add a virus preservation solution (virus transport medium).
For different detection purposes, we need to use different virus preservation solutions.
At present, it mainly includes inactivated type and non-inactivated type. In order to meet different detection requirements and different laboratory conditions for virus detection, it is very necessary to use different preservation solutions.
Flocked Sterile Swabs

Sterile Flocked Nasopharyngeal Swab, 100% nylon flocked swab that provides exceptional absorption quality.

The principle of flocking swab precipitation.

1. Through the directional friction effect of the fiber layer of the flocked swab, the laboratory operator can complete the cell sample.

The unique structure of the top of this swab can greatly increase the number of samples collected

2. Flocked Swab is ideal for collecting large amounts of cells & rapid elution of the specimens instantly released into the transport medium.

More than 95% sample release rate. Very easy to elute.

3. The capillary movement between the nylon fibres at the top of the flocking swab forms a strong hydraulic pressure for absorbing liquid or cell-like samples.

Why flocked swabs are more beneficial for micro DNA collection.

1. The top of the traditional cotton swab, may even lead to false-negative results of the test.

2. The top of the flocking swab has a unique structure, which can almost completely extract and separate trace DNA, so the flocking swab has more obvious advantages in collecting trace DNA.

Made of non-inhibitory DNA amplification materials. It has been verified that it can be directly amplified by PCR, eliminating the need for extraction steps.

About viral transport media

At present, it mainly includes two types: inactivated and non-inactivated.

Flocked Swab With Vtm Kits Leading China Manufacturer

Flocked Swab With Vtm Kits Leading China Manufacturer

Inactivated preservation solution:

It can lyse and inactivate the virus in the sample so that the virus loses its infectious activity.

It can effectively prevent the secondary infection of operators.

But it also contains inhibitors, which can protect the viral nucleic acid from degradation.

Therefore, the experimenter can perform follow-up detection by NT-PCR.

Stored at room temperature for a long time, saving the storage and transportation costs of virus samples.

Non-inactivated preservation solution:

The non-inactivated preservation solution of the present invention can maintain the in vitro activity of the virus and the integrity of the antigen and nucleic acid, protect the viral protein shell, and maintain the originality of the virus sample to a large extent.

Not only for nucleic acid extraction and detection (PCR test) but also for virus culture and isolation.

  The CellMedical virus sampling tube has a thickened and leak-proof design to ensure that the sample does not leak during transportation. It is a virus transport medium (VTM KITS) that complies with WHO regulations and biosafety regulations.

Viral Transport Medium Tube Suppliers

Viral Transport Medium Tube Suppliers

CellMedical produces and sells medical swabs, sampling swabs, sterile swabs, flocking swabs, sponge swabs, nasal swabs, throat swabs, nasopharyngeal swabs, gynecological swabs, genetic swabs, forensic swabs Swabs, oral swabs, nucleic acid swabs, new crown swabs, antigen swabs, anterior nasal swabs, sterilized swabs, collection swabs, flocking cotton swabs, sampling cotton swabs, etc.

Cell medical (Dongguan) Co., Ltd. is a Class II medical device manufacturer integrating R&D, production, sales and service.

The company is committed to providing cells, Virus, Microorganism Collection & Storage & Shipping Solutions.

Cell medical (Dongguan) Co., Ltd. was established in 2009, the company is located in Chang’an, Dongguan.

We mainly produce flocked sampling swabs, sponge sampling swabs, preservation transport media, virus sampling tubes and saliva collectors.

Cell medical (Dongguan) Co., Ltd China Vtm Swab Supplier And Manufacturers

VTM Kit, Viral Transport Media manufacturers, suppliers & exporters in china. Vtm SWAB collection kit compatible with its PCR test

To provide cell, virus, microbial sample collection, storage and transportation solutions for life sciences. Forensic identification, CDC, in vitro diagnostics and medical testing.

After more than 10 years of unremitting efforts and the pursuit of excellence in quality,

Today, CellMedical has become a Class II medical device manufacturer integrating R&D, production, sales and service.

Medical care means high technology and rigour. We always adhere to the concept of “survive by quality and develop by innovation”.

The company has an 8,000-square-meter workshop, a 3,500-square-meter GMP workshop and a 600-square-meter laboratory.

The sterile sampling swabs we produce have a high collection volume and release volume, which greatly enhances the accuracy of the inspection;

Well received by domestic and foreign customers. The company has passed ISO 13485 quality system, and flocking and sponge swabs have product registration certificates, CE and FDA certifications.

ABOUT VTM kits and swabs manufacturer

ABOUT VTM kits and swabs manufacturer

Flocked Swab Influenza

Flocked Swab Influenza | Comprehensive Flu Swab Test Guide

Flu Flocked Swab Influenza

Influenza refers to the common cold, which is an acute respiratory infectious disease caused by the influenza virus.

It is highly contagious and mainly spreads through droplets, such as coughing and sneezing. Influenza generally occurs in winter and spring.

The current influenza detection method is the rapid influenza antigen detection method, which detects “flux A” and “flu B” antigens.

Laboratory staff collect samples through throat swabs.

In fact, in inspection work, it is important to know the quality of the specimen in order to obtain accurate and reliable results.

Throat swab specimens: Professionals can avoid many false-negative influenza tests caused by improper specimen sampling.

The precautions for flu throat swabs are basically the same as those for nucleic acid detection throat swabs. Because the same part is sampled.

There are two types of flu throat swabs: nasopharyngeal swabs and oropharyngeal swabs.

What precautions should I take when taking a throat swab test for flu?

1. Oropharyngeal swab The collection method of the oropharyngeal swab is to let the subject open his mouth, then use a long pharyngeal swab to wipe the patient’s pharynx, bilateral frontal arches and tonsils, and take out the local secretions. Into the catheter of the throat swab and sent to the laboratory for testing.

2. Nasopharyngeal swabs The collection method of nasopharyngeal swabs is to use sterilized throat swabs to penetrate deep into the nasal cavity of the subject and reach the nasopharynx, and extract secretions and nasopharynx by rotating or wiping.

Epithelial cells put a section with secretions and epithelial cells into a sterile container and then carry out pathogenic detection.

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Flu swab material

Swab options for flu testing include flocked swabs, cotton-tipped swabs, rayon tipped swabs, and foam-tipped swabs.

Cotton tip swab:

The original swab tips were all cotton, mainly based on their cleaning power and water absorption. Cotton swabs are very inexpensive and readily available, and are widely used in medical wound management after sterilization with ethylene oxide or autoclaving, as well as in forensic crime scene forensics. In the absence of alternatives, cotton swabs can be used in almost a variety of scenarios.

However, cotton-tipped swabs also have some problems. Due to the low release rate of cotton, natural material for samples, and some of the natural fatty acids in it can damage microorganisms, they are less and less used for sample collection.

Rayon head swab:

Rayon—a synthetic fiber made from wood pulp. Although classified as synthetic fiber, it is essentially a natural material. Compared to cotton, rayon is produced during the process of removing substances that may damage the sample or react with the sample during transportation and handling , so it is generally used for sampling for diagnostic testing.

Polyester Fiber Tip Swabs:

The head material of the polyester fiber swab is made of polyester long fiber winding, which was first introduced into the field of medical testing by DuPont. Polyester fibres are proven for microbial collection, rapid diagnostics, and PCR testing.

Polyester swabs have a high release rate but are more expensive than cotton and rayon swabs.

Foam tip swab:

China Medical Nasal Foam Swab Factory And Manufacturers

China Medical Nasal Foam Swab Factory And Manufacturers

Swabs made from medical-grade polyurethane are an excellent material for diagnostics, especially cell sampling. The swab tip of this swab is usually manufactured as a sheet with a surface hole count of 100ppi (holes per inch).

This material has good absorption of hydrophilic substances and poor absorption of hydrophobic substances. Used in some scenarios that require resistance to chemical corrosion. Also used for DNA and microbial sampling.

Flocked Swabs:

Flocking technology was first developed for cosmetic and industrial production. (Learn more)

After the flocking process was introduced into swab production. It replaced the traditional swab head, and the swab head was brought to a new level.

vtm swab

Due to the flocking process and the multi-branched polyester fibre material used, the flocked swabs have a very high absorption and release rate and are proven to be equally efficient for molecular sampling and absorption. Designated by some institutions for nucleic acid sampling as well as some research areas for genomic analysis.

The evolution of swabs is not limited to changes in materials. New demands in the fields of nursing, testing, and scientific research make swabs continue to evolve in multiple dimensions. The swab also not only acts as an applicator, but also acts as some transport medium.

Precautions include the following:

① Do not drink water before the throat swab test, at least 30 minutes in advance, because drinking water before the test will dilute the virus attached to the pharynx, especially drinking hot water will inhibit the activity of the virus.

In order to improve the accuracy of throat swab nucleic acid detection, do not drink water 15 to 30 minutes before the test to ensure that the throat swab has high accuracy.

②. For patients with good throat exposure, it is not recommended to take too long “ah~” sounds to reduce the risk of occupational exposure to the sampler.

③ To prevent vomiting, do not eat within two hours before the throat swab test.

④. Do not smoke, drink, or chew gum within half an hour before the throat swab test.

During the throat flocked swab sampling, the patient may have clinical symptoms such as nausea or nasopharyngeal discomfort, but the symptoms can subside quickly, so the patient should not be nervous and cooperate actively during the examination. At the same time, the subjects should not smoke, drink, or chew gum within half an hour before the sample collection.

If it is because of the throat swab the child, the parents must soothe the child’s emotions, communicate with the child patiently, and try not to move the child’s head as much as possible.

Deep Nasal Swab Virus Respiratory Kit

Deep Nasal Swab Virus Respiratory Kit

As of April 30, local time, the number of new coronavirus patients in the United States has reached 81.2 million, and the number of deaths due to new coronavirus infection has exceeded 992,000.

As the government ramps up testing for Covid-19, many of us ordinary people are now being tested for Covid-19.

What is Deep Nasal Swab?

Deep Nasal Swab ( nasopharyngeal swab ) is actually a relatively long collection swab, similar to a relatively long sterile swab.

Its main function is to take nasopharyngeal secretions for bacterial culture and drug sensitivity tests.

The source of infection in the nasopharynx and the microorganisms in the nasopharynx were selected and identified by bacterial culture and drug sensitivity test.

Then a drug susceptibility test can be done to determine which drugs are sensitive so that sensitive drugs can be selected for treatment.

So that a better curative effect can be achieved, so the nasopharyngeal swab is actually a flocking swab for collecting nasopharyngeal samples.

China Sterile Flocked Nasopharyngeal Swab GMP Factory and Manufacturers.

China Sterile Flocked Nasopharyngeal Swab GMP Factory and Manufacturers.

Why deep nasal swab for covid?

The Deep Nasal Swab test: to collect cells deep in the nasal cavity because the nostrils by themselves do not provide a sufficiently accurate sample.

The collected fluid samples are sent to a laboratory for PCR testing (polymerase chain reaction), a standard scientific procedure that involves using samples provided by patients to build models of their DNA.

In this system, technicians can look for evidence of the genetic material (RNA) from the new coronavirus, which is wrapped in the patient’s own DNA if they are infected with the virus.

Both Public Health England and the US Centers for Disease Control and Prevention (CDC) prefer to use Deep Nasal Swab because it is so accurate.

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Unfortunately, for suspected Covid-19 patients, it can be uncomfortable.

During the operation, the medical staff is gentle and skilled, so there will be no pain.

What is the correct depth and length of nasopharyngeal swab collection?

See the length of the nasal swab? See how deep it goes into your nostrils?

The length of the nasal swab is normally about 15cm, and it should enter about 2/3 of the time when doing the collection.

How Accurate Is The Nasal Swab

The nasopharyngeal swabbing is generally the preferred method of specimen collection for COVID-19 testing.

About the distance from the tip of the nose to the earlobe, insert a thin cotton swab into the nostril, from the lower nasal passage to the posterior wall of the nasopharynx, and then turn the front to take a sample. The swab will have a significantly insufficient depth of entry. So the posture must be correct.

When the throat swab enters in the direction of the earlobe if it encounters resistance, it needs to adjust the direction, rotates it slightly, and cannot forcefully enter it.

Otherwise, damaged. Until the bottom of the rhinitis is reached, there is a general sense of resistance against a wall.

When you feel a sense of resistance, you have reached the bottom of the nasopharynx. At this time, you need to keep the nasopharyngeal swab at the bottom of the rhinitis for 10-15 seconds. After fully contacting the secretion, rotate it and pull it out.

Deep Nasal Swab Manufacturer Virus Respiratory Kit

Specifically designed for the collection, transport and preservation of virus-containing samples such as influenza, covid-19, avian influenza, and respiratory viruses such as hand, foot and mouth. 2-8 ℃ can be stored and transported for a short time, long-term storage should be at -80 ℃ or below.

Disposable medical sample collection swab, consisting of a plastic rod with and a flocked fibre tip 

VTM (non-inactivated version) and VTM-N (inactivated version) are available for selection.

Ready-to-use tear-off packaging, is convenient and quick, to avoid possible cross-contamination during use.

Equipped with a biosafety sample bag, which is convenient for placing samples and paper documents, the transfer is safe and reliable.

Product number product description
VTM-CM-0403

VTM-CM-0202

 

VTM-CM-0203

10ml sample transport tube contains 3ml VTM transport medium, 1 sampling swab, 1 biological specimen bag

 

5ml sample transport tube contains 2ml VTM transport medium, 1 flocked swab for sampling, 1 biological specimen bag

 

5ml sample transport tube contains 3ml VTM transport medium, 1 sampling swab, 1 biological specimen bag

Sampling swabs include nasopharyngeal swab (Deep Nasal Swab) or oropharyngeal swabs

 

Disposable Virus Sampling Tube Manufacturers

Disposable Virus Sampling Tube Manufacturers

What kind of virus sampling tube do you know? Does the following look like what you know? The following is introduced to you by Disposable Virus Sampling Tube Manufacturers — Cell medical (Dongguan) Co., Ltd.

What is Virus Sampling Tube? When should the virus preservation solution be used?

Disposable Virus Sampling Tube Kits

Disposable Virus Sampling Tube Kits

Virus transport medium, virus preservation solution: a protective liquid medium added to the virus sampling tube to protect the samples after nasopharyngeal swab sampling.

Generally, in the process of nucleic acid detection, we cannot directly conduct nucleic acid PCR experiments at the sample collection site.

If we need to check the samples collected by the flocked swab, we need to add the virus preservation solution.

Why use a virus sampling tube?

First of all, we have to understand what is a virus? Why does it need a virus sampling tube?

virus sampling tube

virus sampling tube

What is a virus?

Virus: a non-cellular form composed of nucleic acid molecules and proteins.

It lives on parasitic hosts and is an organic species between living and non-living bodies.

It is one end of DNA or RNA wrapped in a protective shell.

Through the mechanism of infection, these simple organisms can use the host’s cellular system to replicate themselves but are unable to grow and replicate independently.

Viruses can infect almost all living organisms with cellular structures.

Virus detection is different from conventional biochemical detection.

The virus itself is a simple microorganism and must be parasitic in living cells.

After sampling, when the virus leaves the host cell, its protein shell and nucleic acid degrade rapidly in the sampling tube.

So that the nucleic acid During the test, it is impossible to determine whether the initially collected sample contains the virus, which is likely to cause false negatives.

A virus delivery medium (virus sampling tube), a general-purpose sampling product: for sampling various virus samples, chlamydia samples, and ureaplasma samples.

Short-term storage and transportation at 2-8°C, and -80°C refrigerator or liquid nitrogen Long-term preservation in the environment.

1. For monitoring and sampling infectious pathogenic microorganisms by disease control departments and clinical departments.

Suitable for influenza virus (common influenza, highly pathogenic avian influenza, influenza A H1N1 virus, etc.), hand, foot and mouth virus and other types of virus sampling. It is also used for sampling Mycoplasma, Chlamydia, Ureaplasma, etc.

2. To transport nasopharyngeal swab specimens or tissue specimens from specific parts from the sampling site to the testing laboratory for extraction and testing.

3. Preserve nasopharyngeal swab samples or tissue samples from specific parts for necessary cell culture.

4. For short-term storage and transportation of virus samples at 2-8°C and long-term storage in a -80°C refrigerators or liquid nitrogen environments.

There are two types of virus preservation solutions: inactivated and non-inactivated

The inactivated virus preservation solution is mainly a virus lysis type preservation solution improved by nucleic acid extraction lysis solution, which is added with a high concentration of lysis salt, which can quickly and efficiently deactivate the virus protein in the sample to be tested and can effectively prevent infection.

At the same time, it also contains an RNase enzyme inhibitor, which can protect virus nucleic acid from degradation.

As long as the subsequent NT-PCR experiment can detect the nucleic acid of the virus, we can diagnose it.

Stored at room temperature for a relatively long time.

The non-inactivated preservation solution is mainly a virus maintenance solution that is improved on the basis of the transport medium.

It can retain the protein coat of the virus and the viral nucleic acid DNA or RNA at the same time so that the virus has the integrity of the protein epitope and nucleic acid in vitro.

Of course, there is also a certain risk of infectivity when the operation is wrong.

It is necessary to keep a strictly low temperature for long-term storage after sampling.

No matter what kind of virus preservation solution it is, we must test it as soon as possible after sampling or keep it strictly at a low temperature to ensure that the detection is accurate.

Due to the rapid reproduction and mutation of the virus, the virus preservation solution plays a crucial role in maintaining the stability of the virus sample.

Manufacturers CellMedical Virus Sampling Tube Kits Advantages

1. Add protein-stabilizing components such as BSA to the sampling solution to reduce the speed of virus decomposition and greatly improve the positive rate of virus isolation.
2. It is stable at room temperature and can keep its activity within 1 year.
3. Gentamicin replaces penicillin to avoid allergic reactions;

4. Using flocked swabs, the sample has a higher collection rate and release rate;
Samples can be stored for a long time (-20 ℃ ordinary refrigerator, -80 ℃ low-temperature refrigerator, -197 ℃ liquid nitrogen);
6. Thickening and anti-leakage design to ensure that the sample does not leak, in line with WHO regulations and biosafety regulations.

Flocked Sterile Swabs

Flocked Sterile Swabs

Disposable sampling swabs, We believe you are familiar with them in the past two years because most of the testing tools used for nucleic acid testing (PCR tests) are disposable sampling swabs.

Usually, we see most nasal swabs and throat swabs, and the sampling swabs we commonly use are flocking swabs.

The flocking swab is a disposable sampling swab composed of a nylon short fibre fluff head and abs plastic rod.

Recently, there have been many concerns about rapid antigen detection on the Internet.

One of them is that if the “single-use sample collection swab” (sampling flocked swab) used in the antigen test is “non-sterile” and “non-sterile”. Bacteria” products. There are risks when using it.

Citizens disinfect the sampling swab with alcohol before conducting antigen testing at home?  ( Alcohol disinfection is not advisable)

Experts and industry insiders say such concerns are unnecessary as long as qualified products are available through formal channels.

Discard damaged or contaminated swabs.

Specimen collection sterile flocked swab

Specimen collection sterile flocked swab

Are there risks to using “non-sterile” “non-sterile” Specimen collection swabs?

There are two main issues that netizens worry about:

One is to worry about the “bacteria” of the sampling swab, which will affect the results of the antigen test, such as “false positives”;

The second is to worry about the “bacteria” of the sampling swab. During the sampling process, “bacteria” will enter the human body with the sampling swab and affect health.

Nasopharyngeal swab test

Nasopharyngeal swab test

Regarding the effect of “bacteria” sampling swabs on antigen test results, experts said that this is a misunderstanding caused by confusing bacteria and viruses.

You know, the antigen test “looks” for the antibodies produced by people infected with the new coronavirus.

The display window of the reagent strip contains a protein that recognizes the antibody, like a dam, blocking the colloidal gold that binds the antibody to the virus. So it appears red in the display window.

Therefore, even if the sampling swab contains “bacteria”, the kit will “ignore” it and focus on “finding” the antibodies produced by the new coronavirus infected person.

Since the kit is not interfered with by “bacteria”, it will not affect the results of antigen detection.

For some people who think that “bacteria” sampling swabs will affect human health, experts say that this may be due to a lack of understanding of “sterile” products.

Sterile

The single-use Specimen collection swab can currently be applied for registration as a second-class medical device, and can also be registered as a first-class medical device (the third-class is the highest level) in the regulatory department.

If it is a Class II medical device, it must meet the sterility requirements when it leaves the factory. While a Class I medical device has no relevant requirements and can be listed in the state of “non-sterile” and “unsterilized”.

Experts said that “sterility” refers to the state of no viable microorganisms. All medical devices must meet certain hygienic requirements, such as strict control of the number of microorganisms before they can be qualified for the market.

Flocked Sterile Swabs

Flocked swabs are mainly used for oral and nasopharyngeal sampling, cervicovaginal sampling, and laboratory testing.

Sterile Flocked Nasopharyngeal Swab is a 100% nylon flocked swab that provides exceptional absorption quality with a flexible handle engineered to reach remote areas of the nasopharynx for specimen collection.

According to different uses, it can also include nasopharyngeal swabs, throat swabs, oral swabs, DNA swabs, and cervical swabs.

It is similar to the above classification, but it is slightly different.

For laboratory testing centres and hospitals.

flocked swab --- CellMedical

flocked swab — CellMedical

What are the advantages of flocked Sterile swabs?

Using nylon fibre flocking technology. The front end of the swab has nylon staple fibres fixed vertically. By making the entire collection area of ​​the swab free of absorbent holes. The sample does not scatter and become trapped in the fibres, facilitating faster and more efficient elution.

This makes flocked swabs ideal for PCR work, as flocked swabs are biocompatible and ideal for PCR work.

COVID-19: Will The Pandemic End in 2022?

COVID-19: Will The Pandemic End in 2022?

Only one month after the US lifted the mask order, Philadelphia will usher in a mandatory mask order again.

Beginning April 18, local time, more than 1.6 million Philadelphia residents must wear masks again when entering indoor public places. Philadelphia became the first major U.S. city to impose a mask mandate as cases rose again.

On April 13, the World Health Organization (WHO) New Crown Pandemic Emergency Committee held a meeting. After discussion, it was determined that the new crown pandemic continued to constitute a “public health emergency of international concern”, and countries were advised to prepare for it at any time. Do a good job in vaccination and PCR swab testing.

nasopharyngeal swab test

nasopharyngeal swab test

WHO Director-General Tedros Adhanom Ghebreyesus said: “It’s far from the time to let our guard down.”

According to the latest data from Johns Hopkins University in the United States. The number of confirmed cases of new coronary pneumonia in the world has exceeded 500 million. And the number of deaths has exceeded 6.1 million.

Endorsed by the WHO, in other words, one in 16 people in the world will carry the covid virus.

Since December last year, Omicron has been rampant around the world, with more than 200 million new confirmed cases worldwide in 2022.

500 million, or 5 billion?

At the same time, many experts and even the WHO believe that the number of truly infected people in the world is far more than 500 million, and may even exceed 5 billion.

Not to mention India, Africa and other countries and regions with poor medical conditions, weak testing capabilities, and chaotic management, even in the United States, the CDC has previously acknowledged that the number of infections reported nationwide is estimated to be less than 1/4 of the actual number of infections.

So, can the covid-19 stop this year?

COVID-19: Will The Pandemic End in 2022?

Faced with this question, WHO spokesman Tarik Jasarevic did not respond positively, but reiterated that in order to end the acute phase of the new crown pandemic, scientists have developed an effective epidemic prevention and control response.

Viral Transport Medium With Swab

Viral Transport Medium With Swab

He also warned: “As the new crown epidemic continues to spread on a large scale around the world, the emergence of more new crown variants and recombinant variants is foreseeable.”

Tedros said that the WHO is currently closely monitoring the development of BA.2, BA.4, BA.5 and other Omicron subtype strains, as well as the recombinant XE formed by the combination of BA.1 and BA.2 evolution.

BA series and X series, how dangerous?

Although the number of new cases around the world has been declining for three consecutive weeks. There are also some countries and regions where new cases are still climbing.

Many Asian countries are experiencing the Omicron wave for the first time. In South Korea, new infections and deaths have continued to climb since February.  The country now has the world’s highest daily average of new confirmed cases for a week. According to a Reuters analysis, South Korea currently has an average of more than 182,000 new confirmed cases per day, accounting for a quarter of the world’s newly confirmed cases.

Some European and American countries have experienced a wave of Omicron infection peaks at the beginning of this year, but the epidemic has recently rebounded.

In Europe, the daily increase of confirmed cases in France has shown a slow upward trend, and the seven-day average of newly confirmed cases in Germany has declined, but it is still at a high level. Reuters pointed out that the number of new cases in Europe is still huge, with more than 1 million new confirmed cases almost every two days.

At present, BA.2 is the main circulating strain in many countries, accounting for 94% of all gene sequencing.

While BA.4 and BA.5: Found in South Africa and many European countries.

Experts believe that if more people can be vaccinated and more people have the tools to fight the epidemic, then we can reduce severe cases and further reduce infections, thereby gradually ending the pandemic.

He also emphasized that it is very important to continue swab testing while the pandemic is still ongoing so that cases can be accurately tracked.

CellMedical produce flocked swabs, VTM kits, and virus transport medium, with multiple automatic production lines(Including automatic VTM tube production line, OEM VTM Tube, Flocked Swab Production Line, etc). learn more.

 

Cell medical (Dongguan) Co., Ltd China Vtm Swab Supplier And Manufacturers

China Vtm Swab Supplier And Manufacturers

China Vtm Swab Supplier And Manufacturers

As a major producer of anti-epidemic materials, China has supplied a large number of urgently-needed materials to countries around the world during the COVID-19 outbreak, making important contributions to global epidemic prevention and control.

Cell medical (Dongguan) Co., Ltd, is a comprehensive high-tech biotechnology company in Chang’an Town, Dongguan City, Guangdong Province. Daily production large number of flocked sampling swabs, “disposable virus sampling tubes”, and “virus transport media” VTM kits” help prevent the epidemic control.

CellMedical is a high-tech biotechnology enterprise, dedicated to the research and development, production and sales of nucleic acid testing, molecular diagnosis, medical testing, virus testing and other medical device products.

Cell medical (Dongguan) Co., Ltd China Vtm Swab Supplier And Manufacturers

Cell medical (Dongguan) Co., Ltd China Vtm Swab Supplier And Manufacturers

Products independently developed by CellMedical.

The company’s independent research and development products include disposable virus sampling tubes, and disposable sampling flocking swabs. Medical cotton swab. Cell preservation solution, virus transport medium, saliva collection device. Transport medium, virus transport medium, single-use sampler, Sample preservation solution. Vtm swab, vtm tube, nucleic acid extraction reagent, gene detection reagent, new coronary pneumonia detection reagent and other products.

What is a virus sampling swab kit?

Covid Swab Test To Your Baby

Covid VTM Swab Test

The virus sampling swab set is a virus sampling and transfer product for virus nucleic acid detection.

It generally consists of a sampling swab, a sampling tube and a virus preservation solution.

For the nasopharyngeal and oropharyngeal new coronavirus sampling swab sets.

Also known as virus transport medium (Viral Transport Medium), referred to as VTM.

According to the composition and function of virus preservation solution, it includes non-inactivated and inactivated types.

The purpose of the single-use virus sampling tube:

Viral Transport Medium With Swab

Viral Transport Medium With Swab

The single-use virus transport medium with tube is our company’s best-selling star product. It is suitable for the collection and transfer storage of various influenza viruses, clinical new coronaviruses, influenza,  measles and other virus samples. nucleic acid extraction and later virus isolation.

It is also suitable for collecting and transporting specimens such as Chlamydia, Mycoplasma, and Ureaplasma urealyticum.

Specimens are usually collected from the oral cavity, throat, nasopharynx, anus, and other human body parts.

Combination features of our single-use virus sampling tube kits (vtm swab kits):

Disposable virus sampling tubes include sampling swabs and sampling tubes (vtm kits).

Flocked Nasopharyngeal Meaning Swab Test Sample Collection Vtm Kit

Test Sample Collection Vtm Kit

1. Sampling flocking swab: our company uses a nylon flocking swab (vtm swab). Because nylon flocking has no toxic effect on microorganisms and viruses and does not contain RNase and DNase.

It can maximize the collection and release of virus samples and ensure the accuracy of PCR test results.

The flocked swab rod: ABS material, with a unique breakpoint design.

Convenient to put into the sampling tube without contamination.

2. Virus sampling tube: The tube body and tube cover are made of polypropylene, which will not deform at high temperature and high pressure (121°C, 15min).  And will not become brittle at low temperatures (-196°C).

Resistant to static extrusion and dynamic impact.

The bottom cone design is resistant to centrifugation and shock.

They are packed with a transport medium (inactivated type, preserved type) for the release and preservation of samples to prevent leakage.

The sampling tube has built-in magnetic beads, which are convenient for elution and facilitate the release of more viruses into the virus transport medium.

Before the higher positive rate of PCR detection, the storage solution in the virus sampling tube was Hank’s solution.

Now, the virus sampling tube preservation solution has been upgraded to CellMedical virus preservation solution.

(that is, UTM, recommended by the World Health Organization and the National Influenza Center of China.)

Based on hank’s solution, BSA, HEPES, amino acids, glycerin and other ingredients. A high PCR test is positive.

Virus preservation solution includes non-inactivated virus transport medium and inactivated virus

In the non-inactivated COVID-19 sampling swab set, the components of the virus preservation solution usually include nutrients (such as salts, proteins, glucose), bacteriostatic agents, buffers, phenol red indicator, etc. required for the survival of the virus.

This virus preservation solution can maintain the activity of the virus to the greatest extent.

Not only for virus detection but also for virus culture and isolation.

In the inactivated new coronavirus sampling swab kit, the components of the virus preservation solution usually include buffers, virus lysing agents (usually guanidines), surfactants, etc.

This preservation solution can directly lyse the virus to release nucleic acid, which is convenient for subsequent nucleic acid detection.

China Vtm Swab Supplier

We are a well-known professional manufacturer of medical sampling and preservation products.

Our company has a number of patents.

Mainly used in genetic testing, biopharmaceuticals, large-scale A-level hospitals, entry-exit inspection and quarantine, diagnostic reagents, CDC, public security criminal investigation, forensic identification and other medical institutions.

vtm swab kits feature

Safety: Contains virus inactivator efficacy to ensure no risk of leakage and infection.
Functionality: Inactivate the virus while protecting the activity of viral RNA and protein, which can be used for viral nucleic acid detection, antigen detection, IgM, IgG antibody detection,) (other products that only preserve RNA are used for viral nucleic acid detection);
Effectiveness: Equipped with a special virus sampling flocked swab, the virus release rate is more than 95% (more than 3 times higher than ordinary cotton swabs).
Stability: It can be effectively stored for 144 hours at 2-8℃, which is convenient for transportation and mailing.
Versatility: Applicable to various viruses such as new coronavirus, influenza, HPV, hand, foot and mouth disease, measles, etc.

Viral Transport Medium With Swab

Viral Transport Medium With Swab

Viral transport medium with swab

The COVID-19 outbreak is expected to have a significant impact on the tedious market for swabs and virus transport media owing to the increasing patient demand for infection diagnosis.

Flocked Swab and viral transport media are expected to grow due to intensive testing of COVID-19 in research institutions and laboratories.

Rising research and development activities to produce COVID-19 vaccines are expected to drive market growth during the pandemic.

The rising number of COVID-19 cases in the global population is expected to drive market growth.

The need to develop vaccines and early diagnostics to treat infections is expected to boost the market growth.

Manufacturing of Viral Transport Medium

Virus sampling tubes are medical device products. The virus sampling tube consists of a sampling flocking swab, virus transport medium and outer packaging. Since there is no unified national standard or industry standard, the products of various manufacturers vary greatly.

CellMedical manufactures viral transport media (VTM) following WHO and CDC recommendations, with or without swabs.

Flocked swab+tube with Viral transport medium

Flocked swab+tube with Viral transport medium

1. Sampling swab:

Virus sample collection flocked swab

Virus sample collection flocked swab

The specimen collection swab directly contacts the sampling site, and the material of the sampling head is closely related to the subsequent detection.

  Synthetic fibres such as PE synthetic fibers, polyester fibres, polypropylene fibers, and rayon fibres should be used for the manufacture of sampling swab tips.

  (1) Natural fibers such as cotton are not recommended

  Because the fiber of cotton has strong adsorption of protein, it is not easy to be eluted into the subsequent preservation solution;

  (2) Nylon fibers are also not recommended

  Because nylon fibers (similar to toothbrush heads) have poor water absorption, the sampling volume is insufficient and the detection rate is affected.

 (3) Do not use calcium alginate sponges or wooden stick swabs (including bamboo sticks) for the head of the sampling swab.

  Because the broken wooden sticks or bamboo sticks containing calcium alginate and wooden components will also adsorb proteins after being soaked in the preservation solution, and even have an inhibitory effect on the subsequent PCR reaction.

Flocked swabs manufacturers

Flocked swabs manufacturers

Features of CellMedical Flocked Swabs:

1. Has extraordinary adsorption energy.

2. It has a release rate of more than 95% for the collected specimens, thus ensuring a high degree of reliability of the results;

3. There is a unique breakable design on the plastic rod, which is convenient for specimen transportation;

4. Sterilized by ethylene oxide or irradiation, individually packaged;

Nasopharyngeal and oropharyngeal swabs. learn more

 

2. Virus preservation solution (virus transport medium): There are mainly two kinds of virus preservation solutions widely used in the market, one is a virus maintenance solution improved based on the transport medium, and the other is an improved nucleic acid extraction lysate. Preservation solution.

3. Virus sampling tube: The material of the storage tube should be selected carefully. Some data suggest that polypropylene (Polypropylene) is related to the adsorption of nucleic acids, especially at high tension ion concentration, polyethylene plastic (Polyethylene) than polypropylene (Polypropylene) Easier to grab DNA/RNA. In addition, when using breakable swabs, the storage tube should try to choose a container with a height of more than 8 cm to prevent the contents from splashing and contaminating when the swab is broken.

What is Virus Sampling Tube

Virus Sampling Tube

4. Water for production of preservation solution: Ultrapure water used for the production of preservation solution should be filtered by an ultrafiltration membrane with a molecular weight of 13,000 to ensure the removal of biologically derived polymer impurities, such as RNase, DNase and endotoxin, and ordinary purification is not recommended. water or distilled water.

About the use of virus sampling tubes

Sampling using virus sampling tubes is mainly divided into oropharyngeal sampling and nasopharyngeal sampling:

1. Oropharyngeal swab sampling:

first press the tongue with a tongue depressor, then insert the head of the sampling swab into the throat to wipe the bilateral pharyngeal tonsils and posterior pharyngeal wall, and wipe the posterior pharyngeal wall with mild force, avoiding touching the tongue department.

2. Nasopharyngeal swab sampling:

measure the distance from the tip of the nose to the earlobe with a swab and mark it with your fingers, insert the sampling swab into the nasal cavity in the direction perpendicular to the nose (face), and the swab should be inserted at least half the length from the earlobe to the tip of the nose. Leave the swab in the nose for 15-30 seconds, swirl gently 3-5 times, and withdraw the swab.

It is not difficult to see from the method of use, whether it is an oropharyngeal swab or a nasopharyngeal swab, sampling is a technical task, which is difficult and easy to contaminate. The quality of the collected samples is directly related to the subsequent testing. If the viral load of the collected samples Low, easy to cause false negatives, difficult to diagnose.

Most of the samples recommended by the kits currently on the market are oropharyngeal swabs or nasopharyngeal swabs and bronchoalveolar lavage fluid. This can greatly reduce the difficulty of the samplers’ work. After all, it is not difficult to collect venous blood samples, and like the detection of hepatitis C RNA, about 5 ml of EDTA anticoagulated blood samples are separated into plasma, and the extracted and purified RNA can fully meet the needs of PCR detection.

Preservation solution features:

Our independent research and development and production, unique cell preservation technology, can be stored at room temperature for more than 3 years after sampling! No need to refrigerate, store and transport at room temperature.

Viral Transport Medium With Swab Factory

Viral Transport Medium With Swab Factory

By Type
Swab Type
Nasopharyngeal swab
Throat swab
Transmission medium
By Application
Coronavirus disease
influenza
herpes simplex virus
other
By end-user
Hospitals and Clinics
diagnostic laboratory
other
geography
North America
The U.S.
Canada
Mexico
Europe
Germany
The U.K.
France
Italy
Spain
Rest of Europe
Asia Pacific
China
Japan
India
Australia
South Korea
Rest of Asia Pacific
The Middle East and Africa
GCC
South Africa
Rest of the Middle East and Africa
South America
Brazil
Argentina
Rest of South America
VTM Collection Kits (VTM Kits) For Diagnosis

VTM Collection Kits (VTM Kits) For Diagnosis

VTM Collection Kits preservation systems such as virus collection.
For the collection and transportation of coronavirus, virus, bird flu, hand rash, and measles. The original aptamer and the original specimen, Chlamydia branch.

Generally, the virus subsystems and components are probed from the mouth, nose, throat, throat swab, etc.: throat probe virus preservation, transportation, and biohazard bags.

The CellMedical Virus Collection and Storage System is compatible with most DNA and RNA isolation methods.

It has been validated for COVID-19 testing.

VTM Kits

VTM Swabs

VTM Swabs

Safe and convenient transportation:
It inactivates microorganisms and viruses for safe and convenient transportation and handling.

To save RNA/DNA:
Used to store total RNA and DNA, including viral RNA and DNA, at room temperature.

Sample Type:
Used to collect a variety of sample types, including nose, mouth, throat, and skin samples.

 

 

 

 

Flocked Swab

Flocked Swab

Nylon flocked swab

Made of nylon fibre flocking technology, the front end is coated with nylon short fibers fixed in a vertical manner.

Increasing the efficiency of collection and release of cellular and fluid samples.

So that there is no absorption hole in the entire collection area of ​​the swab.

The collected sample does not disperse and remains in the fibre, facilitating faster and more efficient elution.

Traditional spun cotton swabs cannot completely collect and elute the sample, while flocked swabs can elute more than 95 per cent of the sample collected.

So the use of flocked swabs has great advantages for a variety of sample collection applications.

Because most of the testing tools used for nucleic acid testing are disposable sampling swabs, we usually see more nasal swabs and throat swabs.

Improve analytical sensitivity, no sample residue, and speed up sample processing.

PS stickers come off easily. Suitable for cervical, nasopharyngeal, oral, forensic collection systems and DNA collection, etc. Individually packaged.

Flocked swabs are biocompatible and ideal for PCR work.

PCR is compatible, free of RNase and DNase, so the new flocked swabs are ideal and a good choice for scientists working with PCR technology.

Flocked swab sampling is more comfortable and easier to use;

CellMedical’s flocked swabs use the existing technology “spraying technology”, which is to vertically attach millions of nylon fibres to the head of the medical swab shaft through electrostatic charges in the flocking hair.

Flocked Nasopharyngeal Swab Suppliers and Manufacturers

Flocked Nasopharyngeal Swab Suppliers and Manufacturers

The vertical nylon fibres resemble a soft brush.

During sampling, the user will have no foreign body sensation.

In addition, different parts have different breaking points of the flocking swabs used, and the thickness of the swab rod is also different.

So there is a big difference in softness.

For example, for nasal swabs, the upper end of the swab rod is thin and soft, and the breaking point is also relatively back.