Combined Throat And Nose Swab

Posted on 2022年5月10日2022年5月10日 by Dr. Lee

What is the difference between a nasal (Nose) swab and a throat swab for nucleic acid testing

The sampling method and location are different. The accuracy rates of the nucleic acid test ( PCR Test ) nasal swabs and throat swabs are usually similar, and the main difference lies in the sampling method and sampling site. For nasal swabs, nasopharyngeal swabs (flocking swabs) are mainly used to test the secretions from the inside of the nasal cavity and the surface of the nasal mucosa through the nasal cavity;

Throat swabs: Health care workers collect samples in the mouth with oropharyngeal swabs. Health care workers take throat samples for testing to determine whether a patient has the new coronavirus.

Are both throat swabs and nasal(Nose) swabs required?

Let’s talk about throat swabs first.
The “oral sampling” and “nasal sampling” mentioned above are actually test methods in which medical staff use medical swabs to collect samples from the pharynx in nucleic acid testing (PCR).

COVID-19: Will The Pandemic End in 2022?

It is very important to continue swab testing while the pandemic is still ongoing

Whether entering from the nasal cavity or the mouth, the specimens we need to collect are pharyngeal secretions, including sputum. Compared with the oral route, nasal sampling can provide better safety protection for the sampling person. Because oral sampling requires subjects to open their mouths wide, this increases the risk of virus transmission by droplets. However, if it is collected through the nasal cavity, the environment is relatively stable, and the medical staff who operate it will be safer.

What is the difference between a throat swab and a nasopharyngeal swab, which is more accurate?

The main difference between nasal swabs and throat swabs lies in the location and material of the specimens, which are usually as accurate. The throat swab is in the pharynx, and the nasal swab needs to go into the nasal cavity, not the external nasal cavity. It needs to use a longer swab and slowly rotate it to the deep part of the nasal cavity, so the parts of the material are different. Nasal swabs are special, and the material is relatively soft, which is convenient for reaching the deep nasal cavity through the nasal cavity. The process of taking it may take longer than that of throat swabs.

Compared with nasopharyngeal swabs, oropharyngeal swab sampling is sometimes difficult to meet the normative sampling requirements due to irritating reactions, and the actions of eating, drinking and swallowing will reduce the oropharyngeal to a certain extent. The virus enrichment of 2000 may affect the positive detection rate of oropharyngeal swabs.

Which is better, nasal(Nose) swab or throat swab?

No matter which one is adopted, the key lies in the depth of the collection, whether the collection is in place and the length of contact time with the deep mucosa.

From the personal experience of the testing population, throat swabs will be less irritating and uncomfortable than nasal swabs.

Sterile Flocked Swab

Oropharyngeal swab

　　• The operation is relatively simple and less irritating, suitable for large-scale screening.

　　• The sampling staff will guide the subject to open the mouth, and then use a sterile long cotton swab to gently scrape the subject’s throat to collect secretions from both palatine arches, pharynx, and tonsils.

Nasopharyngeal swab

　　• The technical requirements are high, the human body does not feel very comfortable, and the accuracy is higher than that of oropharyngeal swabs. For key groups such as isolation points.

　　• The sampling staff will insert a long sterile cotton swab into the nostril of the subject, and reach the mucous membrane deep in the nasopharyngeal cavity, stay for a few seconds to soak the secretion, and then take it out.

Who is not suitable for nasal swab

What is A Covid-19 NP Swab?

When collecting nasal swab specimens, the flocked swab ( learn more ) will enter the nasal cavity.

f the medical staff operates in a standardized manner, it will reduce the irritation to the mucous membranes.

But because we can’t see the sampling position of the pharynx.

It mainly relies on the hands of medical staff to feel the resistance, so the technical requirements of the operator are very high, and the tools used are also more complicated.
The improper operation will cause certain irritation to the nasal mucosa, so it is not recommended for patients with sinusitis and allergic rhinitis to do nasal swabs to avoid damage to the nasal cavity.

How to overcome the discomfort of throat swab

When collecting throat swab specimens, the oropharyngeal flocked swab will cause certain irritation to the pharynx. For some people with the sensitive pharynx, nausea and vomiting may occur.

Recommended to relax before collecting specimens.

Don’t get too nervous. If you feel discomfort in your throat after collection, you need to eat less spicy, irritating and greasy food, drink more water, eat more vegetables and fruits, and arrange rest appropriately. Generally speaking, it does not take long to return to normal.

Experts said that the study found that the nucleic acid-positive duration of feces or anal swabs of some infected people is longer than that of the upper respiratory tract. Increasing anal swab sampling can improve the detection rate and reduce missed diagnosis; but anal swab sampling is not convenient enough, and currently only for isolation. Points and other key groups to use.

What is viral transport medium ?

Posted on 2022年5月6日2022年5月6日 by Dr. Lee

Viral transport medium is a protective liquid medium added to the virus sampling tube to protect the samples after nasopharyngeal swab sampling and is usually called virus preservation solution in China.

Usually, in nucleic acid testing (PCR swab test), we cannot perform nucleic acid PCR directly at the sample collection site.

We need to add virus preservation solution (VTM) to the samples collected by swab for transfer check.

Viral Transport Media Kits Manufacturer

What is a virus?

Viruses are microorganisms whose structure is very simple.

There is no way to complete the process of self-replication.

They need the help of host cells and the nutrition of the host to complete virus replication.

The virus can infect humans as well as many other animals.

Influenza viruses such as common infectious diseases are usually RNA viruses.

There are many common viruses that cause human infection, which can cause respiratory diseases, such as cold virus, influenza virus, HIV and influenza A virus.

Since it has no cellular structure of its own, the virus itself cannot replicate.

But invades the gene into the host cell and replicates the new virus with the help of the latter’s replication system.

In conclusion, viruses are diverse and can cause damage to multiple parts of the body. “

After the virus sample is collected, in order to maintain the activity of the virus sample and prolong the survival time of the virus in the sample, the sampling swab ( flocking swab ) will be put into the preservation solution ( viral transport media ) for preservation and transportation.

What is the viral transport medium used for?

PCR test

The inactivated viral transport medium can perform protein denaturation on fresh clinical virus specimens to inactivate the virus. Prevent secondary infection and ensure the safety of transportation and testing personnel. The inactivated samples can be used with a variety of virus extraction kits.

The nucleic acid extraction instrument can quickly extract nucleic acids.

At the same time, with the respiratory pathogen PCR detection kit (VTM Kits) to achieve rapid detection. The specificity and sensitivity are not affected.

Virus preservation solution has many functions:

1. The operation is simple, and the liquid contains ingredients that can denature proteins, thereby inactivating the virus;

2. Contains inhibitors to protect the stability of viral nucleic acid to a greater extent and greatly improve the nucleic acid extraction rate;

3. Stored at room temperature for 12 months before sampling.

The airtightness is good, which is convenient for storage and transportation and saves transportation costs.

Cell medical (Dongguan) Co., Ltd.

Viral transport media include inactivated and non-inactivated viral transport media.

Contains Hank‘s Liquid, Potassium Chloride, Magnesium Chloride, Calcium Chloride, BSA, etc. The combination of various antibiotics has antibacterial and antifungal effects. Bovine serum albumin (BSA), as a protein stabilizer, can form a protective film on the protein shell of the virus. Making it difficult to decompose and ensuring the integrity of the virus; Hank’s buffer The neutral environment constructed by the agent helps to increase the survival time and infection stability of the virus.

What is viral transport medium?

Nasopharyngeal Swab

Inactivated and non-inactivated virus preservation solutions: usually used for the collection and transportation of clinical influenza, avian influenza, hand, foot and mouth virus, measles and other virus specimens, as well as specimens such as mycoplasma, ureaplasma, chlamydia, etc.

1. For monitoring and sampling of infectious pathogenic microorganisms by disease control departments and clinical departments.

It is suitable for a sampling influenza virus (common influenza, highly pathogenic avian influenza, H1N1 influenza virus, etc.), hand, foot and mouth virus and other types of viruses.

2. To transport nasopharyngeal flocked swab specimens or tissue specimens from specific parts from the sampling site to the testing laboratory for PCR extraction and detection.

3. Preserve nasopharyngeal swab samples or tissue samples from specific parts for necessary cell culture.

Pooled Sample Test Viral Transport Media Kits Manufacturer

Posted on 2022年5月5日2022年5月5日 by Dr. Lee

The epidemic is an order, prevention and control are a responsibility, and life is more important than Mount Tai.

One-time use of Viral Transport Medium accelerates production, Cell medical (Dongguan) Co., Ltd. has a daily production capacity of more than 1 million sets of Viral Transport Media kits.

One-time use Virus Sampling Tube, Accelerated Overtime Production, 10ml Viral Transport Media Tube, 20ml Viral Transport Media Tube, 30ml Viral Transport Media Tube.

20-in-1: Pooled Sample Test, originally originated from a single set of samples to 5-in-1, 10-in-1, and maybe 30-in-1, 40-in-1, and 50-in-1 in the future.

The purpose of collecting and mixing is to improve efficiency and quickly screen positive patient samples.

How strong is the detection ability of 10 people’s sample nucleic acid (PCR test) mixed together?

The new wave of the epidemic has affected the hearts of people all over the world. Many people are cheering on the Internet to overcome the epidemic. However, in the recent period, the outbreak of asymptomatic patients and local confirmed patients has not yet reached an inflection point. cases increased.

Why do 10-in-1 Pooled Sample Test?

Mainly because of the following three advantages.

1. The speed of nucleic acid detection can be increased by 10 times.

Citizens line up in an orderly line for PCR swab testing

In the past nucleic acid testing, each person took a test tube.

After the test, we put the sample into the test tube for preservation.

The samples of 10 people: Stored in a test tube.

If tens of thousands of people in the city do nucleic acid swabs alone.

Then, we need millions and tens of millions of collection tubes and a large number of medical personnel.

In this way, the speed of nucleic acid detection will be very slow. Unable to achieve the desired effect.

2. It can quickly identify the positive infected people in the crowd.

Now the infected people are all asymptomatic patients with fever and no cold. It is impossible to detect them by ordinary methods. Only through nucleic acid testing can the hidden dangers in the crowd be excluded.

If everyone is tested individually, the speed of nucleic acid testing will be particularly slow. Over time, people queuing for nucleic acid testing are likely to cause cross-infection.

Completing the test as soon as possible and excluding infected people from the crowd as soon as possible can also reduce the scope of infection, and the mixed detection method for each person can improve the speed and reduce the scope of infection.

If there is one positive in it, wouldn’t it cause cross-infection?

Even if the other nine were negative, they would definitely be implicated.

3. Can reduce the cost of nucleic acid testing.

Although in some places our nucleic acid tests are all free, and people do not need to pay a penny, that is because all these nucleic acid costs are paid for by our government.

Our government will uniformly purchase test reagents for nucleic acid detection, and then uniformly pay for some of the testing costs.

There are millions of people in a city, and the cost of these nucleic acid tests is a lot of money.

So what is the principle behind this 10-person sample being mixed together?

Nucleic acid detection using this mode is to deal with large-scale nucleic acid detection.

Each group of 10 people, after completing the test, put the flocked swab samples into a collection tube, and then centrally send them to the local laboratory for testing.

Medical Swab Test Kit specimen collection sterile nylon flocked swab

If these 10 people are all negative, then it proves that these 10 people are all safe and do not need separate isolation and separate testing.

If one of the 10 people is positive, the remaining 9 people will have special epidemic prevention personnel.

These 9 people will be sent to the isolation area for individual isolation, and then each person will be tested individually every day.

After 14 days of isolation, in In the past 14 days, the results of these 9 people are all negative, which can ensure safety and allow them to return to normal life.

Nucleic acid detection using this mode is to deal with large-scale nucleic acid detection.

Each group of 10 people, after completing the test, put the flocked swab samples into a collection tube, and then centrally send them to the local laboratory for testing.

Pooled Sample Test Viral Transport Media Kits Manufacturer

Viral Transport Media Kits Manufacturer

Cell medical (Dongguan) Co., Ltd.

Product name: Disposable virus sampling tube ( Viral Transport Media)

Model: CM-F005-30 (12ml)

Specification: 12mL/tube

Type: inactivated/non-extinguishing/sample release agent

Scope of application: nucleic acid sampling, for new coronavirus sampling, COVID-19, coronavirus sampling, nucleic acid sampling, collection, transportation and storage of virus samples, etc.

Contraindications: none

20 in 1 virus sampling tube Manufacturer: Cell medical (Dongguan) Co., Ltd.

Output: 200,000 sets per day

10 mixed 1 production capacity of 1 million sets per day

Throat swab production capacity: 10 million per day.

Flocked Swab Influenza | Comprehensive Flu Swab Test Guide

Posted on 2022年5月4日2022年5月4日 by Dr. Lee

Flu Flocked Swab Influenza

Influenza refers to the common cold, which is an acute respiratory infectious disease caused by the influenza virus.

It is highly contagious and mainly spreads through droplets, such as coughing and sneezing. Influenza generally occurs in winter and spring.

The current influenza detection method is the rapid influenza antigen detection method, which detects “flux A” and “flu B” antigens.

Laboratory staff collect samples through throat swabs.

In fact, in inspection work, it is important to know the quality of the specimen in order to obtain accurate and reliable results.

Throat swab specimens: Professionals can avoid many false-negative influenza tests caused by improper specimen sampling.

The precautions for flu throat swabs are basically the same as those for nucleic acid detection throat swabs. Because the same part is sampled.

There are two types of flu throat swabs: nasopharyngeal swabs and oropharyngeal swabs.

What precautions should I take when taking a throat swab test for flu?

1. Oropharyngeal swab The collection method of the oropharyngeal swab is to let the subject open his mouth, then use a long pharyngeal swab to wipe the patient’s pharynx, bilateral frontal arches and tonsils, and take out the local secretions. Into the catheter of the throat swab and sent to the laboratory for testing.

2. Nasopharyngeal swabs The collection method of nasopharyngeal swabs is to use sterilized throat swabs to penetrate deep into the nasal cavity of the subject and reach the nasopharynx, and extract secretions and nasopharynx by rotating or wiping.

Epithelial cells put a section with secretions and epithelial cells into a sterile container and then carry out pathogenic detection.

Flu swab material

Swab options for flu testing include flocked swabs, cotton-tipped swabs, rayon tipped swabs, and foam-tipped swabs.

Cotton tip swab:

The original swab tips were all cotton, mainly based on their cleaning power and water absorption. Cotton swabs are very inexpensive and readily available, and are widely used in medical wound management after sterilization with ethylene oxide or autoclaving, as well as in forensic crime scene forensics. In the absence of alternatives, cotton swabs can be used in almost a variety of scenarios.

However, cotton-tipped swabs also have some problems. Due to the low release rate of cotton, natural material for samples, and some of the natural fatty acids in it can damage microorganisms, they are less and less used for sample collection.

Rayon head swab:

Rayon—a synthetic fiber made from wood pulp. Although classified as synthetic fiber, it is essentially a natural material. Compared to cotton, rayon is produced during the process of removing substances that may damage the sample or react with the sample during transportation and handling , so it is generally used for sampling for diagnostic testing.

Polyester Fiber Tip Swabs:

The head material of the polyester fiber swab is made of polyester long fiber winding, which was first introduced into the field of medical testing by DuPont. Polyester fibres are proven for microbial collection, rapid diagnostics, and PCR testing.

Polyester swabs have a high release rate but are more expensive than cotton and rayon swabs.

Foam tip swab:

China Medical Nasal Foam Swab Factory And Manufacturers

Swabs made from medical-grade polyurethane are an excellent material for diagnostics, especially cell sampling. The swab tip of this swab is usually manufactured as a sheet with a surface hole count of 100ppi (holes per inch).

This material has good absorption of hydrophilic substances and poor absorption of hydrophobic substances. Used in some scenarios that require resistance to chemical corrosion. Also used for DNA and microbial sampling.

Flocked Swabs:

Flocking technology was first developed for cosmetic and industrial production. (Learn more)

After the flocking process was introduced into swab production. It replaced the traditional swab head, and the swab head was brought to a new level.

vtm swab

Due to the flocking process and the multi-branched polyester fibre material used, the flocked swabs have a very high absorption and release rate and are proven to be equally efficient for molecular sampling and absorption. Designated by some institutions for nucleic acid sampling as well as some research areas for genomic analysis.

The evolution of swabs is not limited to changes in materials. New demands in the fields of nursing, testing, and scientific research make swabs continue to evolve in multiple dimensions. The swab also not only acts as an applicator, but also acts as some transport medium.

Precautions include the following:

① Do not drink water before the throat swab test, at least 30 minutes in advance, because drinking water before the test will dilute the virus attached to the pharynx, especially drinking hot water will inhibit the activity of the virus.

In order to improve the accuracy of throat swab nucleic acid detection, do not drink water 15 to 30 minutes before the test to ensure that the throat swab has high accuracy.

②. For patients with good throat exposure, it is not recommended to take too long “ah~” sounds to reduce the risk of occupational exposure to the sampler.

③ To prevent vomiting, do not eat within two hours before the throat swab test.

④. Do not smoke, drink, or chew gum within half an hour before the throat swab test.

During the throat flocked swab sampling, the patient may have clinical symptoms such as nausea or nasopharyngeal discomfort, but the symptoms can subside quickly, so the patient should not be nervous and cooperate actively during the examination. At the same time, the subjects should not smoke, drink, or chew gum within half an hour before the sample collection.

If it is because of the throat swab the child, the parents must soothe the child’s emotions, communicate with the child patiently, and try not to move the child’s head as much as possible.

Disposable Virus Sampling Tube Manufacturers

Posted on 2022年4月29日2022年4月29日 by Dr. Lee

What kind of virus sampling tube do you know? Does the following look like what you know? The following is introduced to you by Disposable Virus Sampling Tube Manufacturers — Cell medical (Dongguan) Co., Ltd.

What is Virus Sampling Tube? When should the virus preservation solution be used?

Disposable Virus Sampling Tube Kits

Virus transport medium, virus preservation solution: a protective liquid medium added to the virus sampling tube to protect the samples after nasopharyngeal swab sampling.

Generally, in the process of nucleic acid detection, we cannot directly conduct nucleic acid PCR experiments at the sample collection site.

If we need to check the samples collected by the flocked swab, we need to add the virus preservation solution.

Why use a virus sampling tube?

First of all, we have to understand what is a virus? Why does it need a virus sampling tube?

virus sampling tube

What is a virus?

Virus: a non-cellular form composed of nucleic acid molecules and proteins.

It lives on parasitic hosts and is an organic species between living and non-living bodies.

It is one end of DNA or RNA wrapped in a protective shell.

Through the mechanism of infection, these simple organisms can use the host’s cellular system to replicate themselves but are unable to grow and replicate independently.

Viruses can infect almost all living organisms with cellular structures.

Virus detection is different from conventional biochemical detection.

The virus itself is a simple microorganism and must be parasitic in living cells.

After sampling, when the virus leaves the host cell, its protein shell and nucleic acid degrade rapidly in the sampling tube.

So that the nucleic acid During the test, it is impossible to determine whether the initially collected sample contains the virus, which is likely to cause false negatives.

A virus delivery medium (virus sampling tube), a general-purpose sampling product: for sampling various virus samples, chlamydia samples, and ureaplasma samples.

Short-term storage and transportation at 2-8°C, and -80°C refrigerator or liquid nitrogen Long-term preservation in the environment.

1. For monitoring and sampling infectious pathogenic microorganisms by disease control departments and clinical departments.

Suitable for influenza virus (common influenza, highly pathogenic avian influenza, influenza A H1N1 virus, etc.), hand, foot and mouth virus and other types of virus sampling. It is also used for sampling Mycoplasma, Chlamydia, Ureaplasma, etc.

2. To transport nasopharyngeal swab specimens or tissue specimens from specific parts from the sampling site to the testing laboratory for extraction and testing.

3. Preserve nasopharyngeal swab samples or tissue samples from specific parts for necessary cell culture.

4. For short-term storage and transportation of virus samples at 2-8°C and long-term storage in a -80°C refrigerators or liquid nitrogen environments.

There are two types of virus preservation solutions: inactivated and non-inactivated

The inactivated virus preservation solution is mainly a virus lysis type preservation solution improved by nucleic acid extraction lysis solution, which is added with a high concentration of lysis salt, which can quickly and efficiently deactivate the virus protein in the sample to be tested and can effectively prevent infection.

At the same time, it also contains an RNase enzyme inhibitor, which can protect virus nucleic acid from degradation.

As long as the subsequent NT-PCR experiment can detect the nucleic acid of the virus, we can diagnose it.

Stored at room temperature for a relatively long time.

The non-inactivated preservation solution is mainly a virus maintenance solution that is improved on the basis of the transport medium.

It can retain the protein coat of the virus and the viral nucleic acid DNA or RNA at the same time so that the virus has the integrity of the protein epitope and nucleic acid in vitro.

Of course, there is also a certain risk of infectivity when the operation is wrong.

It is necessary to keep a strictly low temperature for long-term storage after sampling.

No matter what kind of virus preservation solution it is, we must test it as soon as possible after sampling or keep it strictly at a low temperature to ensure that the detection is accurate.

Due to the rapid reproduction and mutation of the virus, the virus preservation solution plays a crucial role in maintaining the stability of the virus sample.

Manufacturers CellMedical Virus Sampling Tube Kits Advantages

1. Add protein-stabilizing components such as BSA to the sampling solution to reduce the speed of virus decomposition and greatly improve the positive rate of virus isolation.
2. It is stable at room temperature and can keep its activity within 1 year.
3. Gentamicin replaces penicillin to avoid allergic reactions;

4. Using flocked swabs, the sample has a higher collection rate and release rate;
Samples can be stored for a long time (-20 ℃ ordinary refrigerator, -80 ℃ low-temperature refrigerator, -197 ℃ liquid nitrogen);
6. Thickening and anti-leakage design to ensure that the sample does not leak, in line with WHO regulations and biosafety regulations.

China Medical Nasal Foam Swab Factory And Manufacturers

Posted on 2022年4月28日2022年4月28日 by Dr. Lee

Nasal Foam Swab Factory And Manufacturers.

Polyurethane foam swabs are ideal for sample collection and rapid elution.

It can immediately release the specimen into the transmission medium and has been widely used in epidemiological detection, molecular genetics, forensics, clinical laboratories and other fields.

Cell Medical (Dongguan) Co., Ltd. is a Class II medical device manufacturer integrating R&D, production, sales and service.

Collection & Storage & transport Solutions.

Composition of foam swabs

152mm Disposable Foam Swab (Sponge Swab)

Medical-grade foam tip of the swab using ultrasonic technology, so the swab contains no adhesive and will not contaminate the contact.

The tips of the foam swabs are designed in a variety of shapes, including original round, rectangular and conical, etc., which can be used on different occasions.

Polyurethane foam nasal swabs

Application of foam swabs

As a biological sample collection swab to collect samples such as throat/nasal/blood DNA and RNA.
Disable medicines can be applied to the wound.
Used to clean various precision instruments, including medical instruments, lenses, printer nozzle solutions, chips, etc.

Features of Polyurethane Foam Swabs

China Medical Nasal Foam Swab Factory And Manufacturers

The fibre-free structure can effectively prevent static electricity and avoid the generation of dust particles.
Multiple particles on the swab trap the collected objects and strongly absorb and lock the solvent.
Because the foam is soft and non-abrasive, it won’t scratch even the most sensitive surfaces.
100ppi medical polyurethane foam tip and rigid polystyrene handle for fast elution of large volumes of liquids and samples.
Has multiple pores to maximize the collection of samples such as mucus.
The handle: Made of materials that are easy to break.
Or designed with breaking points, which allow you to easily break the swab, which makes it more convenient for users to handle samples.
It releases the specimen immediately into the transport medium for applications in microbiology testing, rapid antigen testing, and molecular and clinical diagnostics.
used to clean various precision instruments, including medical instruments, lenses, printer nozzle solutions, chips, etc.

Cell Medical (Dongguan) Co., Ltd. was established in 2010, the company is located in Chang’an, Dongguan.

We mainly produce flocked swabs, sponge sampling swabs, preservation transport media, virus sampling tubes and saliva collectors.

Committed to providing cell, virus, microbial sample collection, storage and transportation solutions for life sciences, CDC, in vitro diagnostics and medical testing.

After more than 10 years of unremitting efforts and the pursuit of excellence in quality, CellMedical has now become a Class II medical device manufacturer integrating R&D, production, sales and service. Medical care means high technology and rigour.

We always adhere to the concept of “survive by quality and develop by innovation”.

ABOUT VTM kits and swabs manufacturer

The company has an 8,000-square-meter workshop, a 3,500-square-meter GMP workshop and a 600-square-meter laboratory.

The sterile sampling swabs we produce have a high collection volume and release volume, which greatly enhances the accuracy of the inspection;

The flocked swab nasopharyngeal swab rod we invented completely solved the hidden danger that the swab would break in the human body.

The company has a wise and forward-looking management team and experienced technical backbones.

CellMedical has passed the ISO13485 quality management system, and all products have CEor US FDA certification.

Flocking swabs and sponge swabs have Class II product registration certificates.

Flocked Sterile Swabs

Posted on 2022年4月23日2022年4月23日 by Dr. Lee

Disposable sampling swabs, We believe you are familiar with them in the past two years because most of the testing tools used for nucleic acid testing (PCR tests) are disposable sampling swabs.

Usually, we see most nasal swabs and throat swabs, and the sampling swabs we commonly use are flocking swabs.

The flocking swab is a disposable sampling swab composed of a nylon short fibre fluff head and abs plastic rod.

Recently, there have been many concerns about rapid antigen detection on the Internet.

One of them is that if the “single-use sample collection swab” (sampling flocked swab) used in the antigen test is “non-sterile” and “non-sterile”. Bacteria” products. There are risks when using it.

Citizens disinfect the sampling swab with alcohol before conducting antigen testing at home? ( Alcohol disinfection is not advisable)

Experts and industry insiders say such concerns are unnecessary as long as qualified products are available through formal channels.

Discard damaged or contaminated swabs.

Specimen collection sterile flocked swab

Are there risks to using “non-sterile” “non-sterile” Specimen collection swabs?

There are two main issues that netizens worry about:

One is to worry about the “bacteria” of the sampling swab, which will affect the results of the antigen test, such as “false positives”;

The second is to worry about the “bacteria” of the sampling swab. During the sampling process, “bacteria” will enter the human body with the sampling swab and affect health.

Nasopharyngeal swab test

Regarding the effect of “bacteria” sampling swabs on antigen test results, experts said that this is a misunderstanding caused by confusing bacteria and viruses.

You know, the antigen test “looks” for the antibodies produced by people infected with the new coronavirus.

The display window of the reagent strip contains a protein that recognizes the antibody, like a dam, blocking the colloidal gold that binds the antibody to the virus. So it appears red in the display window.

Therefore, even if the sampling swab contains “bacteria”, the kit will “ignore” it and focus on “finding” the antibodies produced by the new coronavirus infected person.

Since the kit is not interfered with by “bacteria”, it will not affect the results of antigen detection.

For some people who think that “bacteria” sampling swabs will affect human health, experts say that this may be due to a lack of understanding of “sterile” products.

Sterile

The single-use Specimen collection swab can currently be applied for registration as a second-class medical device, and can also be registered as a first-class medical device (the third-class is the highest level) in the regulatory department.

If it is a Class II medical device, it must meet the sterility requirements when it leaves the factory. While a Class I medical device has no relevant requirements and can be listed in the state of “non-sterile” and “unsterilized”.

Experts said that “sterility” refers to the state of no viable microorganisms. All medical devices must meet certain hygienic requirements, such as strict control of the number of microorganisms before they can be qualified for the market.

Flocked Sterile Swabs

Flocked swabs are mainly used for oral and nasopharyngeal sampling, cervicovaginal sampling, and laboratory testing.

Sterile Flocked Nasopharyngeal Swab is a 100% nylon flocked swab that provides exceptional absorption quality with a flexible handle engineered to reach remote areas of the nasopharynx for specimen collection.

According to different uses, it can also include nasopharyngeal swabs, throat swabs, oral swabs, DNA swabs, and cervical swabs.

It is similar to the above classification, but it is slightly different.

For laboratory testing centres and hospitals.

flocked swab — CellMedical

What are the advantages of flocked Sterile swabs?

Using nylon fibre flocking technology. The front end of the swab has nylon staple fibres fixed vertically. By making the entire collection area of the swab free of absorbent holes. The sample does not scatter and become trapped in the fibres, facilitating faster and more efficient elution.

This makes flocked swabs ideal for PCR work, as flocked swabs are biocompatible and ideal for PCR work.

Viral Transport Medium Tube Suppliers

Posted on 2022年4月22日2022年4月22日 by Dr. Lee

PCR Swab Test detection disposable virus sampling tube inactivated non-inactivated production supplier

Viral Transport Medium Tube: virus transport tube, which consists of a virus storage tube and virus storage solution.

Virus transport tube: specially designed in combination with subsequent PCR instruments for the rapid detection of viral diseases.

The virus preservation solution ( Viral Transport Medium) is a protective liquid medium added to the virus sampling tube to protect the samples after nasopharyngeal swab sampling.

Includes inactivated viral transport media and non-inactivated viral transport media.

Usually, during nucleic acid detection, nucleic acid PCR cannot be performed directly at the sample collection site.

If the samples collected by flocked swabs need to be transferred for inspection, VTM needs to be added.

Virus detection is different from conventional biochemical detection.

The virus itself is a simple-structured microorganism that must be parasitic in living cells.

After sampling, the virus leaves the host cell. Its protein shell and nucleic acid are quickly degraded in the sampling tube.

So it is impossible to determine whether the initially collected sample contains the virus during nucleic acid detection, which may easily lead to false negatives.

Viral Transport Medium Tube Suppliers

　　The non-inactivated virus preservation solution contains a variety of solution components that are beneficial to the cultivation of virus cells. Which can ensure the integrity of the virus and help increase the survival time and stability of the virus.

　　A virus is a non-cellular life form that consists of nucleic acid molecules and proteins or only proteins, an individual is a small and simple structure that contains only one nucleic acid (DNA or RNA). Without a cellular structure, viruses cannot replicate themselves, but instead, insert genes into host cells and use the latter’s replication system to replicate new viruses. Common infectious diseases are usually RNA viruses, such as influenza virus, HIV virus, H1N1 virus, etc.

After the collection of virus samples, stored and transported in a virus preservation solution to maintain the activity of virus samples and prolong the survival time of viruses in the samples.

Viral Transport Medium with Flocked Swab

　　In addition, we also provide inactivated virus sampling tubes, which can make the sample infective. Thus improving the safety of sample storage and transportation. The product is supplied in bulk liquid medium for further processing, such as into smaller sample tubes.

Inactivated or non-inactivated virus preservation solution. Its basic function is to protect the integrity of virus or viral nucleic acid and ensure the accuracy of viral nucleic acid detection.

Both VTMs have their own advantages.

CellMedical’s virus sampling tubes with a flocked swab to help users collect samples, and there are a variety of swab models to choose from.

　　NOTE: For large-scale nucleic acid testing in non-risk areas during a pandemic, high-volume viral transport media that can hold 5 or 10 swab samples can greatly reduce testing costs.

Characteristics of non-inactivated virus transport media

　　VTM can safely transfer viruses, chlamydia and mycoplasma for further research and analysis.

　　The special formulation ensures optimal sample recovery and the added antibiotic inhibits the contaminating growth of bacteria and fungi.

　　Bovine serum albumin (BSA) acts as a protein stabilizer, but the protein coat of the virus forms a protective film. Making it difficult to decompose and ensuring the integrity of the virus.

　　Hanks’ buffer (HBSS) creates a neutral environment, which helps increase the survival time of the virus and the stability of infection.

　　This product is also equipped with flocked swabs to help users collect samples, and there are a variety of swab models to choose from.

2-3 ML UTM Tube Np Flocked Nasopharyngeal Instruction Swab Test

Applications of Viral Transport Medium Tubes

　　Non-inactivated virus preservation solution: for the preservation and transportation of clinical influenza, avian influenza (such as H7N9). Hand, foot and mouth disease, measles and other viral specimens and mycoplasma, urea. Chlamydia and other living specimens.

　　It is suitable for a variety of applications including classical cell culture methods, and diagnostic tests. And molecular biology techniques (including PCR)

Viral Transport Medium Tube Suppliers Manufacturer

Cell medical (Dongguan) Co., Ltd China Vtm Swab Supplier And Manufacturers

VTM Kit, Viral Transport Media manufacturers, suppliers & exporters in china

The CellMedical production site covers an area of 15,000 square meters, with its own injection moulding production workshop. A thousand-level purification workshop, and more than ten automatic packaging production lines.

We support custom production, OEM and so on, and develop products with customers.

Virus sampling tubes and saliva collection devices can ensure the safety and stability of samples during transport;

Swabs using jet dense nylon fibre technology correspond to soft or brush texture swabs according to different analysis items, which have reached the maximum collection volume.

Disposable injection-moulded swab rods with breaking points and flocking technology. To enhance the adsorption/release of specimens and improves the sensitivity of the analysis.

No sample entrapment, heralding faster and fewer sample transfers.

CellMedical’s sampling flocked swab: made of plastic rod + ABS. Which is harmless to microorganisms and can maximize the collection and release of specimens.

The main products of Cell Medical (Dongguan) Co., Ltd. are disposable virus sampling tubes, virus sampling tube sets, disposable sampling flocking swabs, nasal swabs, throat swabs and other disposable medical equipment consumables.

Sold well at home and abroad. And the superior product quality and high-quality service attitude have won praise from many customers.

Anterior Nasal Swab VS Nasopharyngeal Swab

Posted on 2022年4月21日2022年4月21日 by Dr. Lee

How do avoid damage to the nasal cavity through nasal swab sampling for nucleic acid detection and antigen detection? Rhinitis patients should pay attention to what?

Standardized collection methods for nasopharyngeal swabs :

Nasopharyngeal Swab

1. The sampler lightly supports the head of the person to be collected with one hand, and sticks the swab into the nostril with the other hand.

And slowly penetrates backward along the bottom of the lower nasal passage. Because the nasal passage is curved, do not use excessive force to avoid traumatic bleeding.

2. When the top of the swab reaches the back wall of the nasopharyngeal cavity, gently rotate it for one week. (If you have a reflex cough, it should stay for a while). Then slowly take out the swab, and immerse the swab head in the matching test strip. In the sampling tube of the virus transport medium.

The nasopharyngeal collection method collects a sample from the nasopharynx, which is the upper part of the throat behind the nose.

Nasopharyngeal Swab Pcr Test

In this test, a small pointed flocked swab is inserted into the nostril parallel to the chin until resistance is felt.

Inserted no deeper than half the distance between the nostril and the ear.

The swab is then swirled a few times while remaining in place, and then slowly removed while gently swirling.

If the flocked tip of the swab is completely saturated with the sample, it may not be necessary to collect samples from both nostrils.

This method is often less comfortable for the patient but is generally not considered painful.

This method is not recommended for self-testing and should only be performed by a healthcare practitioner.

Swabs for use in the nasopharynx are designed with a micro-tip made of ultra-fine flocked material and a thin, flexible handle usually made of polystyrene.

Standardized collection methods for nasal swabs (anterior nasal swabs):

Anterior Nasal Swab

1. The collected person first used toilet paper to remove the snot, and then tilted his head slightly.

2. The sampler lightly supports the head of the person to be collected with one hand, holds a swab with the other hand and sticks it into one nostril. And slowly goes back along the bottom of the lower nasal passage for 1-1.5 cm. And then sticks to the nasal cavity and rotates at least 4 times. (The residence time is not long. less than 15 seconds). Then repeat the same procedure in the other nasal cavity using the same swab.

3. After slowly taking out the flocked swab, immerse the swab head in the sampling container containing the preservation solution that comes with the test strip.

Precautions:

1-1.5cm deep into the nasal cavity (about 1cm for children).
Rotate 4-5 times against the nasal cavity (time not less than 15 seconds).
Bilateral nasal collection from the same swab.

Standardized collection methods for oropharyngeal swabs (pharyngeal swabs):

Oropharyngeal sampling swab

1. The head of the person being collected is slightly tilted, the mouth is wide open, and the mouth shape is “ah”, exposing the pharyngeal tonsils on both sides;

2. Pass the swab across the base of the tongue, and wipe the pharyngeal tonsils on both sides of the subject with slight force back and forth at least 3 times.

And then wipe the posterior pharyngeal wall up and down at least 3 times.

And immerse the swab head in the preservation solution provided with the test strip. in the sampling container.

Why do nucleic acid testing (PCR swab test), and what can be detected?

Nucleic acid testing is to find direct evidence of the presence of the virus.

A positive nucleic acid test for the new coronavirus pneumonia indicates that the subject has the virus in the body and may be infectious.

If accompanied by fever, respiratory symptoms or other clinical characteristics of patients with new coronary pneumonia, combined with a positive nucleic acid test, a patient with new coronary pneumonia can be diagnosed; if there are no clinical symptoms and a positive nucleic acid test result, it can be determined as an asymptomatic infection. Therefore, nucleic acid detection is of great significance as a standard for diagnosing new coronary pneumonia.

Nasopharyngeal swab test and Anterior Nasal Swab test, which is better?

As we all know, nucleic acid detection generally takes throat swab detection, and throat swab detection is divided into nasopharyngeal swab detection, Anterior Nasal Swab, and oropharyngeal swab detection. The difference between them is that the sampling sites are different, but there is no essential difference. Most medical institutions use oropharyngeal swab testing because this testing method is less uncomfortable for the sample and more convenient for sample collection.

For the sampling of the new crown antigen professional version and home self-test version. Because this method is less invasive, and generally more comfortable for the patient.

Reuse Nasopharyngeal Swabs Disadvantage

Posted on 2022年4月20日2022年4月20日 by Dr. Lee

Nasal swabs reused at an Indonesian airport? What are the dangers of reusing nasal swabs?

Since the epidemic, the term nasal swab testing has entered our lives. Basically, you will be asked to do a nucleic acid test when you are on a business trip or travelling. After the test is completed, the sterile flocked swab will be processed for medical waste. However, news broke out recently that refreshed the three views, and netizens called out “there is no bottom line”!

According to reports, employees of a medical company in Indonesia were found to be repeatedly using sterile nasal swabs when testing airport passengers. At present, more than 9,000 passengers are expected to be affected.

After investigation, the Indonesian police found that the employees involved first performed Nasopharyngeal Swabs tests on passengers with sterile nasal swabs every day, then cleaned the used sterile swabs with alcohol, and then packaged them for use by the next batch of passengers. . This behaviour is outrageous.

Contents of this article

1. What are the dangers of reusing nasal swabs?

2. Why are the swabs for PCR Swab Test put together?

3. What should I pay attention to when doing nucleic acid testing?

4. Will the swabs for nucleic acid testing be reused?

What are the dangers of reusing nasopharyngeal swabs?

The nose is a barometer of human health. When there are lesions in the body, the colour of the snot changes to yellow or green. Nasopharyngeal swabs are a test sampling method to assess the presence of respiratory viral or bacterial infections by collecting samples from the surface of the respiratory mucosa.

As a rule, nasal swabs cannot be reused. If the nasal swab is reused, the consequences will be disastrous.

If the nasal swab is reused, it will increase the risk of virus infection. Previously, a British research team found that two kinds of cells in the nose may be the other infection sites of the new coronavirus. A clinical study found that the viral load of nasal flocked swabs The amount is significantly higher than that of throat swabs. If nasal swabs are reused, it is likely to cause cross-infection and expand the scope of infection.

On the other hand, it may lead to inaccurate test results, false positives or false negatives. It may cause psychological panic and unnecessary treatment to the subjects, and false negatives may mean that the subjects cannot find out that they have been infected in time, miss the best treatment time, and even cause more people to be infected.

Nasopharyngeal flocked swab CellMedical

Why are the sample collection swabs for nucleic acid testing all put together?

This kind of multi-person mixed inspection can improve efficiency and reduce costs.

Mixed sampling testing refers to mixing samples from multiple people (generally no more than 10 people) into the same test tube for testing, improving testing efficiency and reducing testing costs, but the waiting time for centralized sampling may be slightly longer. According to the voluntary principle, the nucleic acid test of all employees can be tested by mixed sampling technology. The laboratory testing time for mixed sample and single-tube testing is the same, which does not affect the time for issuing the testing report.

The so-called five-in-one and ten-in-one mixed sampling detection technology are to put 5 or 10 individual swabs into a collection tube. When the test result is negative, the mixed sample is negative, and the mixed sample is 5 people. or 10 people are safe;

If there is a positive result, the relevant department will be immediately notified to temporarily isolate the 5 or 10 subjects in the mixed tube, take a single tube swab again for the review, and then determine which of the 5 or 10 people is positive.

What should I pay attention to when doing a nucleic acid test (PCR test)?

Pcr test nasal swab and an antigen test difference for covid 19

Today, many people who travel to and from high-risk areas of the epidemic require nucleic acid testing.

So, what should we pay attention to when doing nucleic acid testing (PCR SWAB TEST)?

Before the nucleic acid test: do not eat within 2 hours, do not smoke or drink within 30 minutes, carry a valid ID card, wear a mask correctly, and inform the testing personnel of past medical history or related matters.

When doing nucleic acid testing: Keep a distance of more than 1 meter when queuing, tilt your head slightly, relax, take a deep breath, and have symptoms such as dry cough or sneezing, use a tissue or cover with your arm.

After the nucleic acid test: leave the collection site immediately, and wipe your hands with hand sanitiser or alcohol.

In fact, whether it is a nasopharyngeal swab or a throat swab, it is an effective virus detection method. Although there will be slight discomfort during the test, it will soon return to normal and will not affect your health. Therefore, if necessary, we must actively cooperate with nucleic acid testing, which is responsible for ourselves and others.

Nucleic acid detection: For virus detection method.

It uses a collection flocked swab to collect a sample from the throat or nose of the tester and then conducts the test to obtain the final result.

Some people found that the flocked swabs for nucleic acid testing will be placed in a bottle(VTM Tube).

This is a mixed test, and most of them occur during nucleic acid testing of all staff, which will not affect the detection effect.

Will the swabs for nucleic acid testing be reused?

Prohibition reused.

In addition to sampling, reagents and other factors, the subject’s own reasons may also lead to “false negatives”.

Not to eat for two hours before the nucleic acid test, not to drink water for the first 30 minutes. And not to smoke, drink water or chew gum to reduce behaviours that may interfere with the test results.

There are other influencing factors before sampling and testing,

1. Please do not take antibiotics a few days before the nasal swab.

2. Do not use disinfectant mouthwash or smear on the affected area a few hours before the nasal swab.

3. Do not eat, smoke, or drink for a few hours before the nasal swab.