Respiratory Specimen Collections

Respiratory Specimen Collections

Respiratory Specimen Collections

Today, with the increasingly severe international COVID-19 epidemic, the correct collection of respiratory samples has become an important prerequisite for ensuring the accuracy of nucleic acid detection results.

However, how to correctly collect respiratory samples? Cell medical (Dongguan) Co., Ltd. summarizes as follows:

Why should respiratory tract samples be collected standardized and correctly?

1. Clear diagnosis;

2. Observe the condition and treatment effect;

3. Guide the formulation of treatment measures;

4. Sample quality directly determines the reliability of test results.

 What are the types of respiratory samples?

1. Upper respiratory tract samples (including swabs, nasal specimens, nasopharynx extracts, pharyngeal gargle and nasal lotion, etc.);

2. Lower respiratory tract samples (such as sputum, tracheal aspirate, lung lotion, etc.);

When is the best time to collect respiratory samples?

Respiratory tract samples were collected as soon as possible after symptoms appeared;

Collect as much as possible within 72 hours of the patient’s fever;

Try to collect before the use of antiviral drugs;

If possible, collect multiple times in multiple days;

What sampling tools are needed to collect respiratory tract samples?

1. Virus sampling kits, including flocked swab, virus sampling tube, virus transport medium, etc;

2. Refrigerated transport box;

3. Personal protective equipment: protective mask (N95), protective glasses.

 How to collect respiratory tract samples?

Oropharyngeal swab sampling process:

Oropharyngeal swab sampling pictures

Oropharyngeal swab sampling pictures

1. The sampler first let the patient sit down, then let the patient tilt his head back and open his mouth.

2. Press the front 2 / 3 of the patient’s tongue with a tongue depressor, and wipe the posterior pharyngeal wall and bilateral tonsils with a nylon flocked swab for 3-5 times to avoid touching the tongue.

3. Take out the rear sampling tube, break the plastic handle at the contact part of the hand, soak the swab into the sampling solution, and tighten the tube cover.

Nasopharyngeal swab:

"nasal

Note : do not use too much force, but try to be as deep as possible, usually more than 5cm, stay for several seconds to absorb secretions, gently rotate and take out the swab, place the sampling tube, break the plastic ellipse at the contact part of the hand, and soak the test piece into the sampling solution, Tighten the pipe cover.

Respiratory Specimen Collections preservation requirements

Those that can be detected within 24 hours can be stored at 4 ℃ and frozen at – 70 ℃ for more than 24 hours.

 

Swab test

Swab test | Disposable virus sampling swab

Swab test | Disposable virus sampling swab

Disposable virus sampling swab, I believe you are no stranger in the past two years. Because most of the detection tools used for nucleic acid test are disposable sampling swabs. Usually, we see most nasal swabs and pharyngeal swabs. But disposable virus swabs are not only useful for nucleic acid testing. What else can a disposable sampling swab do? Let’s get to know.

What can a disposable virus swab be used for?

In addition to nucleic acid detection, scientists can also use disposable sampling swabs for microbial collection. They are usually used for virus detection and research in hospitals or laboratories. Researchers use disposable sampling swabs to detect biological samples in natural cavities of human or animals. Such as throat, nose, mouth, vagina and so on. It is necessary to collect oral epidermal cells and nasal virus samples with a sampling swab, store the cells and samples in the sampling tube and transfer them to the laboratory for examination.

Oropharyngeal swab sampling

Oropharyngeal swab sampling

Operation (use) method of disposable sampling swab:

Take pharyngeal swab as an example:

① Tear open the packaging bag of the disposable sampling swab and take out the disposable sampling swab from the bag;

Note: please do not let the disposable sampling swab touch the place outside the throat to avoid pollution.

② Put a disposable sampling swab into the mouth and quickly wipe the palatal arch and throat (or lesion) on both sides

③ Take out the swab, put it into the disposable virus sampling tube, break the disposable sampling swab at the broken place and discard the tail;

④ Tighten the sampling tube, put the virus sampling tube into the biosafety bag and submit it for inspection in time.

Note: please do not shake the virus sampling tube excessively to avoid dilution and loss of samples. After sampling, do not touch other objects with a disposable sampling swab.

How to carry out COVID-19  nasal swab test?

The doctor shall wear protective clothing, mask, gloves and mask to let the patient take a proper position.

Gently insert the flocked sampling swab into the nose, rotate it for three times, take it out and put it into the sample tube with protective solution, and screw the cover. Then label it, write the date, and send it to the laboratory for nucleic acid test of nasopharyngeal swab.

 

What is a COVID-19 swab test?

Swab test, namely nucleic acid test. The substance test by nucleic acid is the nucleic acid of virus. Nucleic acid detection is to collect the presence of viruses in the respiratory tract, blood or feces of patients, and determine whether they are infected by COVID-19. Therefore, once detected as nucleic acid “positive”, it can prove that there is a virus in the patient’s body.

SARS-CoV-2 nucleic acid detection process.

The usual sample types include throat swabs, nasal swabs, sputum, bronchoalveolar lavage fluid, alveolar lavage fluid and so on.

The sampling personnel shall conduct PCR detection as soon as possible after obtaining patient samples.

After the testing institution receives the sample, the laboratory personnel shall extract nucleic acid from the sample. And the nucleic acid extraction reagent shall use the nucleic acid extraction kit specified in the approved product manual.

Disposable virus sampling swab material.

At present, because of its stable and reliable performance and excellent absorption and elution capacity, nylon flocked swabs are widely used in COVID-19 sampling.

Swab test result

Swab testing for novel coronavirus pneumonia usually takes 4-6 hours to produce results, while rapid examination takes 2-3 hours. However, the reagents used in each hospital are different, so the time of results is also different.

COVID-19 positive results:Maybe infected.After 24 hours of self isolation, the positive patients need to conduct swab test again.

If the two results are positive, the next step is to improve CRP, blood routine, chest CT and other tests to determine whether COVID-19.

When COVID-19 nucleic acid test is negative once, it should be combined with the clinical symptoms and epidemiological contact history of patients. Because a COVID-19 nucleic acid swab test is negative, it can not completely exclude the infection of COVID-19.

 

Is anal swab nucleic acid test more accurate than nasopharyngeal swab?

Is anal swab nucleic acid test more accurate than nasopharyngeal swab?

Is anal swab nucleic acid test more accurate than nasopharyngeal swab?

Nucleic acid detection:generally carried out by sampling pharyngeal swabs in the nasal cavity and oral cavity.

Now began to increase the anal swab test, we are also curious about this test method. So, is anal swab nucleic acid detection more accurate than nasopharyngeal swab? How to sample for anal swab test?

Is the nucleic acid detection of anal swab more accurate than that of nasopharyngeal swab?

In the screening of New Coronavirus pneumonia, we mainly used the oropharyngeal swab nucleic acid test. Because the reason is convenient and quick, suitable for large-scale screening. The accuracy of nasopharynx swab for new crown nucleic acid detection is higher than that of oropharyngeal swab, but the human body feels uncomfortable.

In last year’s test, researchers found that many infected people had negative pharyngeal nucleic acid.But their anal swabs were still positive for longer.

The combination of the two in nucleic acid detection can improve the detection rate and reduce the proportion of missed diagnosis.

However, anal swab sampling is inconvenient and not suitable for large-scale screening and testing in the community.

For some asymptomatic or mild infections, the condition recovers quickly after infection. And the pharyngeal nucleic acid may not be detected in 3 to 5 days.

The researchers found that the duration of nucleic acid positive in feces or anal swabs of some infected people was longer than that in the upper respiratory tract.

Therefore, increasing anal swab nucleic acid detection can improve the detection rate of infected patients and reduce missed diagnosis.

Although nucleic acid detection has the advantages of high sensitivity and short detection cycle, it also has some disadvantages.

Different from the direct isolation of live virus from human body, nucleic acid detection adopts an indirect method, which may cause false negative.

Anal swab & test tubes

Anal swab & test tubes

How to sample for anal swab test

1. Soak the swab in normal saline, insert it into the anus of 2-3 cm, wipe it from the folds around the anus, or rotate it gently in the anus. And then insert it into the test tube containing normal saline.

2. For fecal swab culture, all the above operations require the use of sterile equipment and the swab into a sterile test tube.

anal swab

Iclean nylon flocked swab

Iclean nylon flocked swab

Iclean nylon flocked swab

Product purpose:

Iclean nylon flocked swab is ideal for bacteriological sample processing, virological cell culture, DFA test, rapid and direct test, enzyme immunoassay test, polymerase chain reaction and molecular diagnosis based test, as well as forensic identification.

For throat sampling of respiratory viruses such as influenza, swine influenza, avian influenza, hand, foot and mouth.

Iclean nylon flocked swab,View more

Iclean nylon flocked swab,View more

Characteristics of sampling swab products:

1. It has extraordinary water absorption capacity, which can increase the number of samples collected on its surface from 20% of traditional sampling swabs to 60%.

2. The release rate of the collected samples is more than 90%, so as to ensure the high reliability of the results.

3. Different preservation solutions were selected for different specimen types.

4. The plastic rod has a unique breakable design to facilitate specimen transportation.

5. Ethylene oxide sterilization, irradiation sterilization, independent packaging.

Iclean gene sampling series flocking DNA oral test pieces are specially used to improve the amount and quality of genomic DNA in oral test piece cells. Oral cell sample is a good non-invasive collection and detection method instead of blood. Combined with icleanhcy’s series of DNA separation and stabilization kits, it can quickly collect high-purity and complete DNA samples.

DNA flocking swab is suitable for human and animal use. It has advantages over other DNA samples in design. Its unique sample matrix and rapid release interface are more conducive to efficient cell collection and maximize DNA yield. The test piece has been sterilized with ethylene oxide and passed the detection of human DNA contamination.

characteristic

The unique test substrate greatly improves the yield of DNA;

Adult oral SWAB piece 1 to 10 μ g DNA;

It is a good alternative to blood collection;

Both human and animal can use it;

Simple and fast operation;

There are two types of single and double disinfection packaging to choose from;

application;

Genotype study;

Veterinary genotyping and diagnosis;

Parent child and genetic services;

Forensic and DNA population studies;

About us

Cell medical (Dongguan) Co., Ltd. produce flocked swabs, VTM kits, virus transport medium, with multiple automatic production lines.We support custom production, OEM and so on, and develop products with customers.

Email:flockedswabs@gmail.com

Sample collection swab :How much do you know about nucleic acid testing

Sample collection swab :How much do you know about nucleic acid testing

Sample collection swab:How much do you know about nucleic acid testing

The spread of the covid-19  is continuing worldwide. Although the global scientific and medical circles are making every effort to fight the epidemic, it is difficult to predict how the epidemic will develop in the future, and its impact on social development has appeared in many aspects.

Currently, COVID-19 cases are over 220 million.

Currently, COVID-19 cases are over 220 million.

In order to fully control covid-19, the general screening of local areas shall be carried out if necessary.

After identifying the detection object, how to detect it?

1、 What specimen to choose?

According to the recommendations of the American infectious diseases association, the following specimens were used:

The sensitivity of simple oropharyngeal swab may not be enough, so it is relatively easy to miss diagnosis.

The sensitivity of alveolar lavage fluid is the highest, but it is obviously not suitable for universal screening.

Nasopharynx swabs and other operations should also be standardized.

Improper operation may make the quality of collected samples not high, thus increasing the risk of missed diagnosis.

2、 Select the time of detection

It is very important for COVID-19 to measure RNA and choose the right time. One analysis included 7 studies, including 2 unpublished reports, to evaluate the detection efficiency of RT-PCR at different time points after exposure to virus :

On the day of exposure to the virus, the possibility of detecting viral RNA is almost zero;

On the fifth day after exposure, that is, the first day after infection, the detection probability was 62%

About the 8th day after exposure, i.e. the 4th day after infection, the probability of detection was 80%

On the 21st day after exposure, i.e. the 17th day after infection, the detection probability was 34%

In conclusion, exposure to COVID-19 may require multiple tests to avoid missed diagnosis. However, it is not recommended to repeat the test within 24 hours of the previous test; The interval between two tests shall be at least 24 hours.

After 28 days of exposure to the virus, if the infection has not been diagnosed, it is not necessary to continue the detection; At this time, it is almost certain that it is not infected.

Nucleic acid detection throat swab  sampling process

The COVID-19 nucleic acid was novel coronavirus, which was collected from sputum or lower respiratory tract by real-time fluorescent RT-PCR. If positive, the new coronavirus could be diagnosed. This is the basis for the diagnosis of new type of pneumonia. In addition to detecting the nucleic acid of the virus, it can also detect whether the virus in the specimen is highly homologous with New Coronavirus. If so, it can be diagnosed as New Coronavirus pneumonia. The virus is highly infectious and has the characteristics of human to human transmission, but the virus is sensitive to temperature and sunlight and ultraviolet rays.

Sample collection, nasopharyngeal swab sampling

Sample collection, nasopharyngeal swab sampling

Sample collection, Oropharyngeal swab sampling

Sample collection, Oropharyngeal swab sampling

The flocked swab is the best raw material for sampling swabs.

 

 

reference

1,Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19, updated December 23, 2020. https://www.idsociety.org/practice-guideline/covid-19-guideline-diagnostics/ (Accessed on January 14, 2021).

2,Kucirka LM, Lauer SA, Laeyendecker O, et al. Variation in False-Negative Rate of Reverse Transcriptase Polymerase Chain Reaction-Based SARS-CoV-2 Tests by Time Since Exposure. Ann Intern Med 2020; 173:262.

 

COVID-19 sampling tools

COVID-19 sampling tools help SARS-CoV-2 precise diagnosis!

COVID-19 sampling tools help SARS-CoV-2 precise diagnosis!

Cell medical (Dongguan) Co.,Ltd. monthly production of millions of virus sampling swabs and VTM kits helps epidemic prevention and control.

What are the covid-19 sampling tools?

Flocked sampling Swabs,VTM Kits,Viral Transport Medium,VIRUS Collection & Transport Kits,Saliva collection kit,Disposable virus sampling tube,Op swabs,Np swabs,etc.

Why use sampling tools?

At present, the global New Coronavirus epidemic has reached a critical stage. The most reliable means of rapid diagnosis is still positive for nucleic acid detection. There has been a great breakthrough in the diagnosis of COVID-19, but clinicians, especially the laboratory doctors, still face the following serious problems:

1. Safety of specimens

The majority of “angels in white”, especially the laboratory doctors, are always facing the risk of virus infection.

Although there are various protective equipment, the risk of infection will increase if we can’t ensure the safety of specimens. Therefore, it is very important to ensure virus inactivation and the safety of collected samples.

2. False negative test results

The existence of false negative puzzles the clinic and affects the accuracy of diagnosis. The biggest problem is sample collection and preservation. The New Coronavirus infection prevention and control program (Fifth Edition) has been published to collect nasal swabs, throat swabs, sputum, lower respiratory tract secretions, blood and feces. The incorrect way of collecting and storing samples will lead to the degradation of viral RNA and directly lead to the false negative test results.

Cell medical (Dongguan) Co., Ltd. provides the perfect solution for sampling tools.

√. Cell medical provides samples of swabs collected from various viral types including New Coronavirus (covid-19) and provides a perfect solution.

√ .It can quickly inactivate viruses including New Coronavirus, influenza A virus and many other viruses.

√ .preservation solution: preserve RNA to prevent degradation.Disposable virus sampling tube.

√ .safety guarantee: vertical design, sampling and preservation in one step to reduce personnel exposure.

Sampling steps of new virus collection tube

1) The collection personnel shall be qualified through biosafety training and have corresponding experimental skills. Requirements for protective packaging of sampling personnel: N95 and above protective masks, goggles, one-piece protective clothing, double-layer latex gloves, waterproof boot covers, etc. in case of direct contact with the specimen, the protective equipment shall be replaced in time.

2) Sample type: pharyngeal swab and nasal swab.

nasal swab_COVID-19 sampling tools

nasal swab_COVID-19 sampling tools

Pharyngeal swab collection method: wipe bilateral pharyngeal tonsils and posterior pharyngeal wall with a plastic rod swab with polypropylene fiber head

Nasal swab collection method: gently insert a plastic rod swab with polypropylene fiber head into the nasopalatine part of the nasal canal, stay for a moment, and then slowly rotate and exit. Take another plastic rod swab with polypropylene fiber head and collect the other nostril wall in the same way.

3) Specimen preservation: immerse the swab head into the tube containing virus preservation solution, discard the handle along the folding point of the sampling swab, and tighten the tube cover.

Notes

The tube containing virus preservation solution another name isvirus sampling tube.

Virus preservation solution is also called virus transport medium.VTM.

 

 

What is genetic testing?

What is genetic testing?

What is genetic testing?

Definition of gene

What we usually call genes is a collection of genes in human cells, called the genome.

Every cell in our body has a complete genome. Inherited from parents and passed on to children.

Genes make people different from animals, make families different from families, and brothers and sisters are similar but different.

These subtle differences often do not exceed 0.5% of genes.

But determine different appearance, personality, genetic characteristics, and our adaptation to the external environment.

Why genetic testing?

It must be noted that various human traits and diseases are the result of the joint action of genes and environment .

Genes only play a partial role in traits, and whether gene expression is also greatly affected by the internal and external environment.

Therefore, gene test reports can not be directly used as the basis for clinical treatment, and it is not advisable to judge the role of genes without individual environment.

On this premise, the gene test report still has a certain reference significance for understanding various characteristics of the human body.

Understand that they carry hereditary pathogenic genes

We can know whether we carry pathogenic genes through genetic testing. For example, people with a family history of genetic diseases, cancer and hypertension. According to the test results, adjust dietary health care and living habits to avoid the occurrence of diseases. If both pregnant couples carry the pathogenic gene of recessive disease at the same time. They can pay attention and conduct further investigation when preparing for delivery.

Select drugs correctly to avoid drug waste and adverse drug reactions

Due to genetic differences, individuals will respond differently to drugs. When taking the same kind of drugs, some people will feel very effective, while others will not only be ineffective, but also have toxic and side effects. When some people use certain drugs, they may also have drug allergy. Through gene testing, we can know everyone’s gene situation, which may play a guiding role in drug use to a certain extent. Again, the drug test report can not be directly used in clinic. The drug selection and use in the treatment of diseases need to follow the doctor’s advice.

Provide scientific health management

Many adverse environmental factors  and bad living habits  will make the human body more prone to diseases. People can understand the occurrence tendency of individuals in different diseases through genetic testing, and make corresponding life adjustment or intervention in order to reduce the risk and delay the occurrence of diseases.

What is the principle of gene testing?

To understand the principle of gene detection, we need to understand the following questions:

Reasons for gene testing

Each person’s human nucleus has 23 pairs of chromosomes, which are composed of DNA and ribosomal proteins. All chromosomes have 3.16 billion base pairs.

When the same base pair position changes (this situation is generally called single nucleotide polymorphism, or SNP), which has a certain impact on human genetics and health, this SNP is the locus in the gene report. At present, there are nearly more than 100 million known or named SNPs.  Most of the differences between human DNA are SNP differences, which is about 0.5% of the total base pairs of human DNA. A large part of gene detection is based on SNP.

Samples for genetic testing

Normal human samples required for gene testing include saliva sampling and blood sampling. For different examination items, excreta sampling and cell slice sampling are also included.

Methods of gene testing

There are several ways to measure related base pair differences (SNPs): PCR, chip, exon, and genome-wide. The number of SNPs detected is dozens, hundreds of thousands, tens of thousands, and all SNPs.

Disposable DNA sampling flocked swab

Oral DNA sampling swab_flocked swab cm-98000

Oral DNA sampling swab_flocked swab cm-98000

1.Specially designed for micro DNA samples at the crime scene, especially for micro samples such as sweat, semen, blood, dandruff, oral cells, etc.

2. It can quickly absorb a small amount of samples and has high release aging rate.

3. The front end is sharp enough to extract cells from the victim or suspect’s fingernails.

4. The swab has a breakpoint, which is convenient for the automatic extraction workstation to extract samples.

5. The whole swab is packed in a transparent plastic tube to avoid biological pollution.

Who can do genetic testing?

① People with family disease history;

② People with bad living habits;

③ People exposed to chemical pollution, heavy metal pollution, nuclear pollution and toxic and harmful substances for a long time;

④ Friends who pay attention to health;

Hello!

When many diseases are diagnosed, it’s too late. Do a good job in disease prevention to make us healthy for a longer time!

 

 

 

COVID-19 Testing: Method of collecting virus swab samples

COVID-19 Testing: Method of collecting virus swab samples

COVID-19 Testing: virus swab

According to New Coronavirus’s pneumonia diagnosis and treatment plan (trial version fourth), to diagnose suspected cases of New Coronavirus pneumonia, we need one of the following etiological evidence:

1. Respiratory tract specimens or blood samples were detected by real-time fluorescence RT-PCR for New Coronavirus nucleic acid positive.

2. Novel coronavirus is highly homologous to respiratory tract specimens or blood samples.

Therefore, novel coronavirus pneumonia is an indispensable part of the specimen collection. So, where to collect specimens? How to collect specimens? How can medical staff protect themselves during collection? What should I do after collection?

How to obtain a virus swab specimen?

We all know that the collection method of virus swab specimen is basically to use the swab to sample the infected place or part of the virus, and then put it into the virus sampling tube containing preservation solution without touching other places, so as to conduct virus detection later.

Specimen type:

1. Upper respiratory tract specimens: including pharyngeal swab, nasal swab, nasopharyngeal extract, etc.

2. Lower respiratory tract specimens: including deep expectoration fluid, respiratory tract extract, bronchial lavage fluid, alveolar lavage fluid and lung tissue biopsy specimens.

3. Blood samples: try to collect anticoagulants in the acute stage within 7 days after onset. The collection volume is 5 ml, preferably fasting blood.

4. Serum samples: try to collect double serum in acute stage and recovery stage.

5. Conjunctival specimens: conjunctival swab specimens shall be collected for cases with ocular infection symptoms.

6. Stool samples: Patients with diarrhea symptoms need to collect stool samples.

COVID-19 Testing: Common virus swab sampling methods

Methods of throat swab collection

Inform the patient of the purpose of examination, collection method and collection time. It is best to collect specimens before using antibiotics.

Objective: To study the clinical effect of the method

Secretions were collected from pharynx or tonsil for bacterial culture or virus isolation to assist in clinical diagnosis and treatment.

Prepare sampling supplies:

Disposable sampling swab, virus sampling tube, tongue depressor and biological bag

Operation method:

(1) Ask the patient to sit down, tilt his head back, open his mouth and make a “ah ~” sound

(2) The sampling personnel shall fix the patient’s tongue with a tongue depressor, and use a disposable pharyngeal swab to pass through the root of the tongue to the posterior pharyngeal wall, tonsil recess and lateral wall;

(3) Repeatedly wipe 3-5 times to collect mucous membrane cells or sputum

(4) . gently remove the swab to avoid touching the tongue, the suspension, the oral mucosa and saliva

(5) Put the swab into the virus sampling tube gently and vertically. The sampling personnel shall disconnect the tail of the flocking swab and leave the tail of the swab completely in the tube.Be careful that the swab does not touch the wall of the tube.

(6) . tighten the cap, mark it, and seal it in the biosafety bag.

(7) The sampling personnel shall send the samples to the laboratory for testing in time. If the sampling personnel cannot send the samples for inspection in time, they shall store them at low temperature

Methods: nasal swabs were collected

Nasopharyngeal swab_COVID-19 Testing: Method of collecting virus swab samples

Nasopharyngeal swab_COVID-19 Testing: Method of collecting virus swab samples

(1) Ask the patient to sit down with his head slightly back and remove the secretion from the front nostril first;

(2)measure the distance from nostril to ear base with swab and mark with finger

(3)gently insert the swab into the nostril until it is marked or stopped when there is obstruction. Let the swab stay in the nose for 15-30 seconds, and then rotate it gently three times.

(4) slowly pull out the nasal swab and quickly put it into the virus sampling tube. Then break the swab, leave its tail and place it completely in the tube.

(5) tighten the cap, mark it, and seal it in the biosafety bag.

(6) If we need to collect from both nostrils, we should use a swab.

(7) It should be sent to the laboratory for testing in time. If it can not be sent for inspection in time, it should be stored at low temperature.

Generally speaking, COVID-19 testing: the main methods of collecting virus swabs are nasopharyngeal sampling and oropharyngeal sampling.

 

Is COVID-19 pneumonia more infectious than SARS?

The effectiveness of infectious disease transmission depends on its basic regeneration index. Novel coronavirus pneumonia is more infectious than SARS at present, with a basic regeneration index of SARS higher than that of SARS.

The novel coronavirus pneumonia is a new disease, and the population is generally immune. Everyone is susceptible and susceptible to infection. The incubation period of COVID-19 also has the ability to transmit, and it has longer infection time. The novel coronavirus pneumonia novel coronavirus pneumonia is also typical of the clinical symptoms, and asymptomatic infections are also contagious, so the infection of new crown pneumonia is higher than SARS.

About us

Cell medical (Dongguan) Co., Ltd.  is a swabs manufacturer. We produce and sell virus sampling related products. Such as virus sampling flocked swabs, VTM kits and virus transport media, and have multiple automatic production lines.  We support customized production, OEM, etc., and develop products with customers.

 

Disposable virus sampling kits

Disposable virus sampling kits

Disposable virus sampling kits

Cell medical (Dongguan) Co., Ltd. _China swab manufacturer.Our flocked swabs are famous for their stable and reliable performance and excellent absorption and elution ability.

We produce flocked swabs, VTM kits, virus transport medium, Disposable virus sampling kits,with multiple automatic production lines.We support custom production, OEM and so on, and develop products with customers.

Email:flockedswabs@gmail.com

Nasopharyngeal Swab & Oropharyngeal Swab

Item No.# Description Sterilization
CM-98000 Oropharyngeal Specimen Collection flocked Swab, Single swab packaging, Sterile,Breakpoint 30mm EO
CM-96000 Nasopharyngeal Specimen Collection flocked Swab, Single swab packaging, Sterile,Breakpoint 80mm EO
CM-93050 Throat Specimen Collection flocked Swab, Single swab packaging, Sterile,Breakpoint 80mm EO
CM-96000N Nasopharyngeal Specimen Collection flocked Swab, Single swab packaging, Sterile,Breakpoint 90mm EO
CM-98000T Medical Flocked Swab With Test Tube, with Individually Wrapped and Sterile Buccal(oral)  Swabs EO
CM-93050T Specimen Collection Swab tube, Individual Sterile Package Oropharyngeal Swabs EO
CM-96000T Nasal Sample Collection Kits,flocked Swab With Test Tube,ndividually Wrapped and Sterile EO

Ethylene oxide sterilization, irradiation sterilization and independent packaging.

Supply Ability:500,000-1,000,000 Pieces per Month

Disposable sampling swab application

The top of the flocked swab is made of nylon fiber. The nylon fiber is successively attached to the surface of the medical ABS rod through the electrostatic field. The layer is completely parallel and perpendicular to the surface of the internal rod for DNA collection.

The collection system adopts nylon flocked swab, which is non-toxic to microorganisms and can maximize the collection and release of samples.

A large number of clinical experiments show that compared with ordinary sterile cotton swab, nylon flocking swab has better effect on the collection and transportation of clinical microbial samples

This is especially true for those specimens that cannot be submitted for examination in time and placed for too long.

Our flocked swabs are famous for their stable and reliable performance and excellent absorption and elution ability.

Product features

1.Non invasive,Non-irritating;

2.Outstanding sample collection and release ability;

3.Rapid Absorption;

4. Increased Assay Sensitivity;

5.Perpendicular Nylon Fibers;

6.Certified Free Of Inhibitors And Interference.

Our FDA & CE certificate can ensure effective and legal customs clearance in your country.

VTM (Viral Transport Medium):Including inactivated and non inactivated.

Quality Certification:MSDS,CE,ISO

Our virus transport medium is based on Hanks equilibrium salt solution (HbSS).

It contains calcium and magnesium, heat inactivated fetal bovine serum, gentamicin and amphotericin B.

The composition and preparation of virus vectors follow the recommendations of who and CDC.

The product is provided in a sterile 13 ml flat bottom tube with or without swabs, providing the greatest range of possibilities for collecting samples.

Inactivated Viral Transport Medium(ITM).

This product is designed for the inactivation of a variety of viruses, such as clinical 2019-ncov, influenza, avian influenza, hand-foot-mouth, measles virus, norovirus, rotavirus and other virus specimens, and for the transportation of the virus nucleic acids. It is compatible with various viral nucleic acid extraction kits available on the market and can achieve seamless connection with downstream nucleic acid extraction.

1. It can not only inactivate the virus, but also prevent nucleic acid degradation.

2. Room temperature transmission

3. The samples can be stored at room temperature for 20 days.

4. It is used to collect, store and transport viruses, chlamydia, mycoplasma and Ureaplasma.

Model Specification
VTM-B-CM010120S 2With Nasal flocked Swab& Throat Swab ;  1ml inactivated medium ;2ml tube
VTM-B-CM010111S With Nasal Swab ; 1ml inactivated medium ;2ml tube
VTM-B-CM010112S With Throat Swab ; 1ml inactivated medium ;2ml tube
VTM-B-CM020220S 2With Nasal Swab& Throat Swab ;  2ml inactivated medium ;5ml tube
VTM-B-CM020211S With Nasal Swab ; 2ml inactivated medium ;5ml tube
VTM-B-CM020212S With Throat Swab ; 2ml inactivated medium ;5ml tube
VTM-B-CM020320S 2With Nasal Swab& Throat Swab ;  3ml inactivated medium ;5ml tube
VTM-B-CM020311S With Nasal Swab ; 3ml inactivated medium ;5ml tube
VTM-B-CM020312S With Throat Swab ; 3ml inactivated medium ;5ml tube
VTM-B-CM040320S 2With Nasal Swab& Throat Swab ;  3ml inactivated medium ;10ml tube
VTM-B-CM040311S With Nasal Swab ; 3ml inactivated medium ;10ml tube
VTM-B-CM040312S With Throat Swab ; 3ml inactivated medium ;10ml tube
VTM-B-CM040520S 2With Nasal Swab& Throat Swab ; 5ml inactivated medium ;10ml tube
VTM-B-CM040511S With Nasal Swab ; 5ml inactivated medium ;10ml tube
VTM-B-CM040512S With Throat Swab ; 5ml inactivated medium ;10ml tube

Non inactivated Viral Transport Medium(ITM).

Application:Nucleic acid detection and virus isolation.

1. Low temperature non freezing storage, does not damage the shell of the virus, and is convenient for long-distance transportation.

2. Applicable to all kinds of swab samples, including oral swab, nasal swab, throat swab, etc

3. It can be used for H1N1 influenza virus and any other virus that can be sampled with a swab.

4. The viral nucleic acid can be extracted with the lentivirus DNAOUT or the lentivirus RNAOUT.

5. Antibiotics in the sampling solution can effectively prevent bacterial and fungal contamination.

6. Bovine serum albumin is added to the sampling solution, which can protect the virus sample and improve the separation rate.

Model Specification
VTM-A-CM010120S 2With Nasal flocked Swab& Throat Swab ;  1ml Non inactivated medium ;2ml tube
VTM-A-CM010111S With Nasal Swab ; 1ml Non inactivated medium ;2ml tube
VTM-A-CM010112S With Throat Swab ; 1ml Non inactivated medium ;2ml tube
VTM-A-CM020220S 2With Nasal Swab& Throat Swab ;  2ml Non inactivated medium ;5ml tube
VTM-A-CM020211S With Nasal Swab ; 2ml Non inactivated medium ;5ml tube
VTM-A-CM020212S With Throat Swab ; 2ml Non inactivated medium ;5ml tube
VTM-A-CM020320S 2With Nasal Swab& Throat Swab ;  3ml Non inactivated medium ;5ml tube
VTM-A-CM020311S With Nasal Swab ; 3ml Non inactivated medium ;5ml tube
VTM-A-CM020312S With Throat Swab ; 3ml Non inactivated medium ;5ml tube
VTM-A-CM040320S 2With Nasal Swab& Throat Swab ;  3ml Non inactivated medium ;10ml tube
VTM-A-CM040311S With Nasal Swab ; 3ml Non inactivated medium ;10ml tube
VTM-A-CM040312S With Throat Swab ; 3ml Non inactivated medium ;10ml tube
VTM-A-CM040520S 2With Nasal Swab& Throat Swab ;  5ml Non inactivated medium ;10ml tube
VTM-A-CM040511S With Nasal Swab ; 5ml Non inactivated medium ;10ml tube
VTM-A-CM040512S With Throat flocked Swab ; 5ml Non inactivated medium ;10ml tube
Disposable virus sampling kits sampling process

Disposable virus sampling kits sampling process

Nasopharyngeal swab sampling_flocked swabs

Nasopharyngeal swab sampling_flocked swabs

Oropharyngeal swab sampling

Oropharyngeal swab sampling

Nasal swab for flu

Nasal swab for flu,Rapid antigen nasal or throat swab

Nasal swab for flu_Rapid antigen (nasal or throat swab) test

Influenza is common in winter and spring. The clinical manifestations are mainly systemic poisoning symptoms such as high fever, fatigue, headache, cough and systemic muscle pain, while the respiratory symptoms are mild.

Influenza viruses are prone to mutation, infectious, susceptible to population and high incidence rate. They have caused many outbreaks in the world, and are important public health issues worldwide.

Why should we detect and prevent influenza?

According to the World Health Organization (WHO), seasonal influenza can cause 3-5 million severe cases and 290000-650000 deaths worldwide every year.

The researchers believe that children under the age of 5 are at high risk of severe influenza, but children under the age of 2 are at the highest risk, and infants under 6 months have the highest hospitalization rate and mortality.

Pregnant women, infants, the elderly, patients with chronic basic diseases and other high-risk groups have a higher risk of serious diseases and death after suffering from influenza.

Nasal swab for flu : common influenza test method

Nasopharyngeal sample collection

Nasopharyngeal sample collection

Influenza is an acute inflammation of the respiratory tract caused by the patient’s infection with influenza virus. The patient can have a series of symptoms such as cough, expectoration, fever, sore throat, stuffy nose, runny nose and general fatigue. In case of influenza, we should conduct relevant examinations in time to further clarify the diagnosis, including the following tests:

First, blood routine test, patients with influenza can promote the increase of lymphocytes. If combined with bacterial infection, there can be the increase of leukocytes and so on.

Second, scientists can culture throat swabs of influenza viruses. In throat swab culture, researchers can detect the related virus.

Third, influenza patients can do second-generation sequencing, including sputum second-generation sequencing, which can determine the type of virus infected.

Fourth, influenza patients can do the detection of respiratory pathogens to further clarify the pathogens of infection.

At present, the two most common influenza tests are rapid antigen diagnostic test  and influenza virus cell culture test. Both tests rely on Nasopharyngeal swabs, pharyngeal swabs, etc. for virus sampling. The most commonly used sampling swab is nylon flocking swab.

Nasal swab for flu:Application

It is suitable for the detection and sampling of COVID-19, influenza virus , hand foot mouth disease virus, COVID-19, measles rubella and other types of viruses.

About nasal swab sampling

Why use flocked nylon swabs?

flocked swabs_Cell medical (Dongguan) Co., Ltd.

flocked swabs_Cell medical (Dongguan) Co., Ltd.

Flocked nylon swab: excellent sample collection / release ability, release rate > 90%.

Conventional fiber swab: the sample is intercepted by the gap in the fiber mass. That is, the sample is penetrated, diluted and intercepted in the fiber.  Acquisition is slow and release is slower.

The sampling time of flocked swab is 3-5 seconds, while that of traditional swab is 15-120 seconds or even longer.

This caused pressure on the staff during the diagnosis process. Only by extracting samples faster can we complete the collection and analysis more efficiently.

Precautions for patients with nasopharyngeal swab:

① Please do not take antibiotics a few days before making nasal swabs;

② Do not use disinfectant mouthwash or smear the focus a few hours before nasal swab.

③ Do not eat, smoke or drink a few hours before doing nose swab.

Precautions for Sampler:

① . the sampler shall stand on the side of the patient for sampling.

② The patient is required to pull down the mask to expose only his nostrils. In case of sneezing reflex, the patient can cover it with elbows or paper towels.

If the sampler is not directly in front of the patient, the exposure risk will be lower.

③ If the patient’s turbinate is hypertrophic, the nasal tract is narrow, and the insertion of the nasal swab feels resistance. Try to change one side of the nasal cavity or directly change to oropharyngeal swab collection.

④ Those with nasal allergy symptoms are easy to induce sneezing. It is recommended to take oropharyngeal swab samples.

⑤ Remember to wear a protective mask / screen. For individuals who are highly suspected or basically diagnosed, or who have severe cough and hiccup, they should put on protective clothing.

⑥ After sampling, replace gloves, disinfect hands, and spray disinfectant where patients have touched.

Finally, we should pay attention to nasal swab for flu in special times. Remember to wear masks and personal hygiene when going out. Once you find the virus, please isolate it to avoid re transmission.