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COVID-19: Main Symptoms

Posted on 2022年6月25日2022年6月25日 by Dr. Lee

The three main symptoms of “new crown”: are fatigue, brain fog and muscle pain, the specific manifestations vary from person to person. Other more common persistent symptoms include shortness of breath, chills, body aches, headache, joint pain, chest pain, cough, and persistent loss of taste or smell.

Flocked Swabs and Custom Swab Manufacturing

ISO13485 Quality Management System Disposable Sampling Swab Production Quality Standard Sterile Swab.

Forgetfulness, anxiety: “I feel useless”

Many people with long-term symptoms report cognitive impairment or memory loss that affects their ability to make everyday decisions, speak, follow directions and drive, and impair their quality of life.

Xiao Liu (pseudonym) works in British media. Three years ago, he suffered from depression. He largely recovered before contracting Covid-19 in November 2021 and has stopped taking antidepressants. But after she contracted Covid-19, the depression returned. The doctor assessed and judged that one of the symptoms of the new crown-brain fog persisted.

“After I got the new crown, I felt that I was ‘brainless’, I didn’t want to do anything, and I was extremely anxious.”

It starts with cold-like symptoms, headache, cough, fever, and loss of taste and smell. There are also chest tightness, shortness of breath, fatigue, insomnia, loss of appetite, forgetfulness, inability to concentrate, unresponsiveness, anxiety, etc.

“The overall condition is not good, and the weight has lost four kilograms”

After Xiao Liu fell ill, the children became sensible. I get up every morning looking for a school uniform to wear, and my 11-year-old will scramble eggs, eat breakfast, and go to school alone. My brother was hungry at night, so he cooked instant noodles and ate them together.

Flocked swab

Xiao Liu remembers coughing for three weeks, being bedridden for a month, and then taking a long sick leave of more than three months.

“I couldn’t get out of bed to cook at all. The children ate takeaways every day, and my mouth ulcers had developed for a long time. Fortunately, some friends helped us and often brought us home-cooked food. At that time, the volunteers in the community even gave me anti-inflammatory drugs. Depression. Come to my house and make sure I take it on time. My family doctor advised me to call my psychiatrist again.”

“The biggest motivator for me was the several home visits from the social worker in charge of child welfare. The kind help made me extremely anxious and insomniac, and I felt like an incompetent mother who couldn’t do even the most basic things to take care of her children.” Covid has cost me! It’s unacceptable to me.”

“Regular doctor consultations and cordial greetings from unit leaders also made me feel like I was a burden. I didn’t want to be sick all the time. Everyday burnout and bedridden made me feel like I was useless.” “

For a long time, Xiao Liu felt that he had Alzheimer’s disease. Can’t remember anything, looking for something every day. It takes a few repetitions to understand what the doctor says. Sometimes after calling in the morning to confirm, call in the afternoon to ask.

“Sometimes I don’t know if I have taken medicine or not. Once I enter the kitchen, I forget what I am doing. I look at the pills with a water glass and ask myself if I just took the medicine or not?”

Because of the confusion caused by many small things, Xiao Liu deeply doubts his ability to do things. She feels that she must first learn to forgive herself and accept herself who is often tired and forgetful now.

Xiao Liu said that now he wants to make himself happier and more optimistic by doing one small thing every day. Doctors want to taper off antidepressants over a year.

Fatigue: “Three hours of sleep when I get back from the store”

Severe fatigue is by far the most common symptom of COVID-19. Other symptoms include muscle pain, hearing and vision problems, headaches, loss of taste and smell, damage to the heart, lungs, kidneys, and intestines, diarrhea, and mental health problems, including depression, anxiety and distraction, and stupor.

Before being diagnosed with “coronavirus”, she had been suffering from persistent fatigue, fever, and loss of smell and taste for months, for which she consulted several doctors of different specialties.

At first, my temperature rose slightly, I felt dizzy, and then my throat started to hurt. A day later, my fever reached 38.5°C.

Later, I went for a checkup and received treatment.

After three weeks of conventional viral infection treatment, tachycardia was found, while fatigue symptoms did not decrease.

Frequent blood tests, blood pressure measurements, and lung monitoring are performed. After taking antibiotics and vitamins for three weeks, the treatment failed, and he underwent ENT, pulmonology, cardiology, virology, rheumatology and immunology tests. Found chronic sinusitis, and heart adhesion, but not sure if it is caused by the new crown, it was still there before.

After a month, blood cell counts stabilized, but mental and physical fatigue and fever persisted.

For seven months, I was unable to concentrate, disoriented, felt hot, shivering, tired, didn’t know when it was going to pass, and felt scared every day.

At the doctor’s advice, make a “resurrection” plan, start walking, but take breaks from time to time, sleep at least three hours after going to the store or spend an hour in front of the computer.

The child is doing nucleic acid nasopharyngeal testing

Feeling changes, headaches, fatigue and brain fog are just a few of the symptoms of ‘coronavirus’

Cognitive Function and Brain Fog: “IQ Decreases…”

“I’m not back to normal, from a cognitive standpoint, I’m not back to where I was before the coronavirus, in terms of focus, agility, flexibility… a year and a half later, I feel like I’ve only lost 30-40 %”. she says. % has been restored. I’m not the same as before, my IQ has dropped. “

“After a year and a half, after a lot of hard work, a lot of self-discipline, and all things considered, my condition has improved. I have anxiety (cognition) and I won’t fully recover, but I’m slowly accepting the possibility.”

Sterile Foam or Flocked Tipped Applicator

Posted on 2022年6月17日2022年6月17日 by Dr. Lee

Sterile Foam or Flocked Tipped Applicator

The outbreak of the novel coronavirus pneumonia in 2020 on a global scale has brought significant losses to human society. Viral nucleic acid detection plays a key role in epidemic prevention and control.

As the first step in viral nucleic acid detection, specimen collection is an indispensable link.

The amount of virus collected and released by sampling swabs is directly related to the positive rate of nucleic acid detection. As the gold standard, nucleic acid detection plays an important role in virus detection, and the role of swabs as a sample collection tool should not be underestimated. Among them, throat swabs and nasal swabs are most commonly used, and anal swabs are also used as auxiliary tests.

During the epidemic, researchers from various countries analysed and found that the efficiency of flocking nasal swab sampling and the acquisition of virus samples were the best.

At the same time, in order to solve the problem of the shortage of nasal swabs.

Nasal swabs

The researchers proposed a combined sampling method of oropharyngeal and nasal swabs to achieve the same effect as nasal swabs.

As the main tool for sampling, swabs have important applications in the fields of forensics, clinical medicine, and environmental testing.

Swabs of different materials, such as rayon, foam, polyurethane, polyester, flocked nylon, etc., will have different structures and performance differences and have different collection effects for different specimens such as protein and nucleic acid, which will affect the detection.

The selection of appropriate swabs according to different sampling samples and testing indicators is very important for testing, and the proper use of swabs is also very important for sample collection and the safety of medical staff.

ISO13485 quality management system for producing disposable sampling swabs, quality standards, and sterile swabs.

Nylon flocking swabs–small nylon fibres to a moulded plastic rod.

This production process significantly increases the surface area of the nylon swab, which is conducive to the adsorption of bacteria and easy release.

Oral Foam Swabs 104mm (with 22mm breakpoint)

The sponge swab is soft in texture and has numerous tiny pores. It has strong adsorption to liquid, can collect more target analytes, increase the number of samples collected, and can release a large number of samples without defibrillation.

How to elute, etc., which will affect the test results. Many factors can affect the swab sampling results.

The cotton swab used to poke the throat or nose during the nucleic acid test of the new crown should be called an aseptic sampling swab, also called a pharyngeal swab. According to different sampling sites, including nasopharyngeal swabs and oropharyngeal swabs.

The swab is in direct contact with the nasopharynx or oropharynx to absorb the secretion sample, then put the head with the secretion into the culture solution, break the handle through the breakpoint, seal the lid and send it for testing.

Nasopharyngeal Sampling Procedure

In this process, the swab involves two links: sampling and elution (release the collected sample into the culture medium). The choice of different materials will affect the efficiency of sampling and release, and also affect the correctness of PCR detection. There are certain requirements for the material of the sampling swab.

PCR TEST

According to different materials, common swabs can be divided into medical cotton swabs, foam swabs and flocking swabs.

Several reports have shown that the sensitivity of medical cotton swabs in collecting respiratory samples is low, and natural fibres such as cotton have strong adsorption to proteins, which is not conducive to the subsequent release in the culture medium.

Generally, cotton swabs also have wooden handles, which may adsorb proteins during storage and interfere with virus detection. In addition, the wooden handle is too hard to break, and can also cause safety problems when sampling.

The US CDC recommends that the swab head material— synthetic fibres. The use of calcium alginate swabs or swabs with wooden shafts may inactivate certain viruses and reduce Accurate substances.

Sterile Flocked Nasopharyngeal Swab: a 100% nylon flocked swab that provides exceptional absorption quality.

We produce flocked swabs, VTM kits, virus transport medium, and Specimen Collection Swab with multiple automatic production lines.

Including automatic VTM tube production line, OEM VTM Tube, Flocked Swab Production Line, etc.

We support custom production, OEM and so on, and develop products with customers.

Flocked Swabs For Sample Collection

Posted on 2022年6月10日2022年6月10日 by Dr. Lee

The nucleic acid test (PCR TEST) uses a flocked swab instead of a cotton swab.

Flocking is a craft, not a material

　　 Flocking is not the fluff of any plant, but a very common fabric treatment process.

Widely used in the textile industry, automobile manufacturing, printing industry, chemical industry and other fields.

　　 The flocking process means vertical fixing of some cut or milled short fibres to some kind of adhesive-coated surface. Short fibres are usually nylon, polyester, or other artificial fibers. The range of planting them is very wide, and surfaces such as cloth, plastic, wood, leather, paper, etc. can be flocked.

　　Flocking only needs three things, 1, short fibers; 2, adhesive, 3, some kind of surface

　　 Flocking is very common in everyone’s life, just usually without realizing it. For example, flocking fabrics can be found on clothes, curtains, carpets, and furniture. Usually, those surfaces that are fluffy and comfortable to the touch are brought by the flocking process.

　　 In addition to the decorative effect, the flocking technology has also been tried by scientists to make graphene lithium battery anode sheets; make special lipophilic and hydrophobic materials to absorb marine oil spills, etc.

The principle of flocking

　　 At present, the most commonly used flocking method is electrostatic flocking. After the fluff enters the high-voltage electric field, it contacts the negative electrode and is negatively charged.

　　 Don’t worry if some fibers fall to the side and don’t stick to the side. After they touch the positive electrode side, the negative charges on the surface are completely neutralized, and they will fall to the negative end due to the force of the electrostatic electric field. Repeat the above movement until they are all stuck.

Flocked swabs for nucleic acid testing

　　 The flocking swabs used for nucleic acid detection are mostly “planted” with nylon short fibers. The reason for choosing flocked nylon over cotton swabs is the functional need for sampling.

Flocked swab

Any material design is purposeful, and flocked swabs for nucleic acid detection need to meet the following characteristics:

　　 ② After the swab is put into the preservation solution, it has to “let go” to release the biological sample, and it cannot hold the sample firmly for a second or divide it. ③ It cannot react with biological samples and destroy the samples.

　　 Because cotton itself has superior hydrophilicity and adsorption, once it comes into contact with the sample, it is like the characters in Qiongyao play. In contrast, nylon flocked swabs are like a scumbag “can take it and put it down.

　　 Therefore, the collection and release volume of nylon flocking swabs is much larger than that of traditional winding cotton swabs. Experimental studies have shown that the collection and release volume of flocking swabs can reach 95% of the samples, while cotton swabs are only about 20%.

　　In fact, the ability of cotton swabs to grasp the sample is not bad, but after inserting the preservation solution, the flocked swab can quickly let go of the sample to be eluted, but the cotton swab will make the cells stuck in the fiber mass and cannot be separated.

　Otherwise, the nucleic acid will be degraded before the detection begins, and the correct result will definitely not be detected.

　　 Because of this, it is superfluous to worry that nylon is a synthetic fiber that is harmful to the human body. Flocked fibers have even been tried in regenerative medicine to help repair damaged bones and cartilage. By implanting the flocked fibrous scaffold, the properties of the extracellular matrix are modeled, allowing stem cells to adhere to it to proliferate and differentiate; and provide sufficient space for the newly synthesized matrix and capillaries to enter.

Flu Test Throat Swab China Factory And Manufacturers

Posted on 2022年5月26日2022年5月26日 by Dr. Lee

Influenza requires a throat swab test. Tests can be used to determine whether a patient is infected with the flu virus, and then targeted treatment can be given.

Influenza patients will have symptoms of dry cough, and they will also have dry cough symptoms after being infected with the new coronavirus, so throat swab tests should be performed for patients who have been in contact with people infected with the new coronavirus or who have been to the epidemic area. Patients infected with the new coronavirus generally do not need a throat swab test to determine whether they are infected with the new coronavirus.

Covid Test Flu Throat Swab

The throat swab detection process is as follows: the tested person needs to sit facing the sampler, raise his chin, and open his mouth wide. in special equipment.

These tests include reverse transcription-polymerase chain reaction (RT-PCR), viral culture, and immunofluorescence assays. All we require is that a health care provider swipe the inside of your nose or the back of your throat with a swab and then send the swab for testing. Results may take one to several hours.

Accuracy of throat swabs for influenza.

A throat flocked swab for influenza is more accurate, but there are no authoritative experimental statistics for its specific accuracy.

Throat swab testing for influenza is very fast, economical, and simple, but if the throat swab is negative.

It does not mean that there is no Influenza that may be caused by contamination of specimens, improper sampling of specimens, etc.

And comprehensive judgment should be made in combination with clinical symptoms, epidemiological history, and antigen testing.

When taking a throat swab for influenza, insert the swab completely into the throat from the oral cavity, and moderately wipe the bilateral pharyngeal tonsils and posterior pharyngeal wall with the throat wall and the reddened part of the palatine tonsil as the centre. But avoid touching the tongue. Then remove the test strip. Insert the sampled swab into the solution in the sample extraction tube

So that the specimen is dissolved in the solution as much as possible, and the results can be observed within 15 to 20 minutes.

After more than 30 minutes, the displayed results are usually not clinically meaningful.

If there are two red lines or three red lines in the patient, it means that the throat swab test for influenza is positive.

And there are two red lines, which usually means that there is influenza A or B. If it is three red lines, it means that it is a mixed infection of influenza A and B.

If only one red line appears, the throat swab is negative.

If the reaction line does not appear, the test is invalid, and it is recommended to use a new test card to test again.

Is it a cold or the flu? How to distinguish?

1. Influenza: fast and furious,

If you feel like you’ve been hit by a truck, you might have the flu. Symptoms such as sore throat, fever, headache, muscle aches, congestion and cough can come on suddenly. Colds are usually less intense and include a runny or stuffy nose. The flu gets better in 2 to 5 days, but you may feel the discomfort for a week or more. Colds come on slowly and last up to 10 days.

2. Fever: Usually means the flu

While some people have a mild fever when they catch a cold, most do not. If you have the flu, your body temperature may reach 38-40°C. The flu tends to be higher in children, and children may also be more likely to develop a fever.

3. Flu: Fatigue can last for weeks

You may start to feel very tired and sore. Fatigue and weakness can last up to 3 weeks, and even longer in older people and people with long-term (chronic) illnesses or weakened immune systems. Colds are self-limiting and you usually get better within a few days, usually 1 week to 10 days.

4. Cold and flu: Both can cause headaches

Like other symptoms caused by a cold, headaches that accompany a cold are still milder than those caused by the flu.

5. Cough: Both colds and flu can cause

Colds and flu are respiratory illnesses that both affect your airways, so both can cause a cough.

Pneumonia is a lung infection that can be a complication of the flu. If you have a persistent cough, fever higher than 38°C, chills, difficulty breathing, shortness of breath or chest pain, please seek medical attention in time.

6. Earache: Maybe from a cold or the flu

Congestion from either disease can raise the pressure in your ears. This affects the Eustachian tube, where the larynx and middle ear communicate. It may cause dull ear pain, hearing loss, and a “popping” feeling in the ears. These symptoms will disappear as the disease improves.

If other symptoms get better and the earache persists or you experience sudden, intense pain, see your doctor. You may have an ear infection that needs treatment.

7. Colds: Usually starts with a sore throat

These early symptoms tend to last 1 to 2 days, and a runny nose and nasal congestion are also common. A sore throat also accompanies the flu, but if it’s the flu, you may feel tired and have other symptoms right away.

8. Stuffy nose: Could mean a cold

Simple nasal congestion without fever and general tiredness tends to lead to a cold, although many flu sufferers also say they have nasal congestion and sneezing.

Both colds and flu can cause sinus infections. In addition to a thick yellow or green snot, a sinus infection can also cause headaches and pain in the forehead, cheeks, and bridge of the nose. Sudden head movements or strains can make the pain worse.

9. Flu throat swabs can quickly identify the flu

Flu Test Throat Swab China Factory And Manufacturers

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The quickest way to find out about your illness is to go to the hospital for a checkup.

A nasal or throat swab can usually tell you if you have the flu virus in 30 minutes or less. If a test shows you have the flu and your symptoms started within the past 48 hours, your doctor may recommend antiviral medication to help you recover faster.

10. Influenza: start antiviral drugs as soon as possible

These medications can give you relief and shorten your condition within 1 to 2 days, especially if you start taking them within 2 days of getting sick. Over-the-counter medications can also relieve symptoms such as coughing and congestion. Read labels and directions carefully so you know what the medicines do and how to use them.

11. Colds: Over-the-counter medications can ease symptoms

12. Hand washing is key

Washing your hands is very important to protect yourself and not spread the flu to others. Wash your hands with soap and warm water, preferably the six-step method. Alcohol-based hand sanitizers are also effective.

Wash your face frequently during cold and flu season, especially after coughing, sneezing, or having a runny nose. What if I can’t find a tissue? Face your elbow when sneezing or coughing instead of covering your mouth with your hand.

13. Get vaccinated

There is now a flu vaccine that protects against the flu, and it’s made from a protein from the previous year’s flu cases. It helps your body prepare to recognize and fight when you’re exposed to the virus again. Note: The flu shot won’t give you the flu!

The flu shot is very important for children over 6 months of age, pregnant women, adults 50 years and older, and people with long-term (chronic) illnesses or weakened immune systems.

Monkeypox Virus Outbreaks Are Containable

Posted on 2022年5月24日2022年5月24日 by Dr. Lee

Monkeypox Virus Outbreaks Are Containable, WHO said available details indicated that human-to-human transmission was occurring among people who had close physical contact with symptomatic cases. The patient’s symptoms were similar to those observed in smallpox patients in the past but were less clinically severe.

These confirmed and suspected cases are mainly from the United Kingdom, Spain and Portugal, with the rest in Australia, Belgium, Canada, France, Germany, Italy, the Netherlands, Sweden and the United States.

The incubation period for monkeypox is usually 6 to 13 days, but it can be between 5 and 21 days.

However, Nick Finn, deputy director of England’s National Infectious Service, stressed that monkeypox does not spread easily from person to person and that the overall risk to the public is low.

An expert from China’s disease control system also told Caijing·Great Health that the spread of monkeypox between people can be said to be very limited, mainly through secretions and other transmissions, and the risk of causing an epidemic is very limited.

How serious is a monkeypox infection?

Before the current outbreak, monkeypox cases scattered in the tropical rainforests of central and western Africa.

Monkeypox Virus VTM Kits

There are two distinct clades of monkeypox viruses, the Congo Basin clade and the West African clade. Monkeypox, caused by the Congo Basin clade virus, has reported a mortality rate of up to 10.6%; while the West African clade virus, which usually causes less severe disease, has a case fatality rate of 3.6%.

In this outbreak, all cases with samples confirmed by polymerase chain reaction (PCR) testing were determined to be infected with the West African branch, meaning relatively low mortality.

The genome sequence of a swab sample from a confirmed case in Portugal showed that the monkeypox virus responsible for the current outbreak closely matched cases exported from Nigeria to the UK, Israel and Singapore in 2018 and 2019.

Initial symptoms of monkeypox infection include fever, headache, swelling, back pain, muscle aches and general weakness. Infected individuals initially have generalized erythema or rash, which then develops into papules on the trunk, face, palms, and soles, which then develop into cysts, which form pus scars and scabs. Sometimes a bit like chickenpox, the infection lasts 14 to 21 days and usually goes away on its own.

The virus can enter the body through broken skin, the respiratory tract, or through the eyes, nose, or mouth. Evidence suggests that the highest risk of infection is in people who have had close physical contact with a symptomatic monkeypox patient.

Of the first nine cases of monkeypox confirmed in the UK, six had had sex with men.

To date, severe cases are more common in children and immunocompromised people, especially those with HIV, and are related to the degree of exposure to the virus, the patient’s health status, and the severity of complications.

Hans Kruger, WHO Regional Director for Europe, also said: “Monkeypox is usually a self-limiting disease and most infected people recover within a few weeks without treatment.

How to get out of Africa and into Europe?

Confusingly, monkeypox occurs primarily in the rainforest regions of central and western Africa. For example, the US recorded two cases of monkeypox in 2021 and the UK reported seven cases, all imported to and from Nigeria. travel history.
However, in this outbreak, it is unusual for confirmed and suspected cases reported in several countries without any travel history to monkeypox-endemic areas.
Australia, Canada and the United States are also among the non-endemic countries reporting monkeypox cases. Health authorities in New York City, home of the United Nations, are also investigating a possible case. A patient at a hospital tested positive on May 19, local time.
These cases are atypical, Hans Krueger said. All but one were not related to travel to monkeypox-endemic countries.
WHO believes that there is an urgent need to raise awareness of monkeypox and implement comprehensive measures to detect and isolate cases, trace contacts, and provide supportive care to limit further spread.

How to stop the spread.

“China has not reported any cases of monkeypox, nor has the virus been found in animal hosts. The current focus is on preventing imported cases,” Tan Wenjie, a researcher at the Chinese Center for Disease Control and Prevention’s Institute for Viral Disease Prevention and Control, said in an interview with the media. (Transport medium )

According to the above-mentioned experts of China’s CDC, at present, the measures to prevent the importation of the monkeypox virus are very strict. Import squirrels, rabbits and other rodents. The possibility of monkeypox being introduced by animals brought by inbound passengers is unlikely and the public need not worry.

Specifically, researchers don’t yet know the animal reservoir of the monkeypox virus.

Since 1970, the monkeypox virus has had sporadic outbreaks in 10 African countries. This is a DNA virus in the genus Orthopoxvirus of the Poxviridae family. In 1958, a group of captive monkeys transported from Africa to Copenhagen, Denmark for scientific research developed the vesicular disease. European scientists isolated the monkeypox virus from monkeys in the laboratory, hence the name “monkeypox virus”.

In 2017, Nigeria experienced its largest outbreak on record. At that time, there were 172 suspected cases, and 75% of the patients were men, aged 21-40. Since then, Nigeria has continued to report monkeypox cases.

Of these, 241 were confirmed cases, including 8 deaths (case fatality rate 3.3%). From 1 January to 30 April 2022, 46 suspected cases were reported and no deaths were recorded.

In 2003, there was an outbreak in the United States, the first time the disease had emerged outside of Africa. The patient was infected due to close contact with marmots. Marmots were infected by various small mammals imported into the United States. There were 81 cases at the time, but there were no deaths.

The cases of monkeypox infection have emerged in multiple countries, and researchers suspect that transmission may have continued for some time because all but one of these cases were not related to travel to monkeypox-endemic countries and were geographically dispersed in Europe and elsewhere.

Matthew Kavanagh, acting deputy executive director of WHO’s AIDS agency, stressed on May 22 that leaders urgently need to strengthen their pandemic preparedness. Including building stronger community-led capacity and human rights infrastructure to Support an effective and de-stigmatizing response to the outbreak.

The above-mentioned experts in the disease control system explained to Caijing.

However, the “early detection” of the monkeypox virus is difficult. The above-mentioned experts in the disease control system said that it takes a certain period of time for monkeypox infection to have clinical symptoms and thus be discovered, which is different from the emergence of viral symptoms in respiratory infections.

COVID-19 Swab Test: What You Should Know

Posted on 2022年5月13日2022年5月13日 by Dr. Lee

An abrupt COVID-19 has brought flocking swabs, nasopharyngeal swabs, oropharyngeal swabs, nucleic acids, antigens, PCR and also other extremely professional terms right into the public eye. Today, CellMedical will certainly offer you preferred scientific research: those aspects of Coronavirus (COVID-19) screening.

What is a flocking swab, nasopharyngeal swab, or oropharyngeal swab?

When nations are executing a new round of nucleic acid screening, a report is spreading out in circles. The basic concept is “the cotton bud used for sampling have reagents on them, which are hazardous”. Some netizens also left a message to the CellMedical firm backstage, saying that after seeing the pertinent reports, the elderly at home shared that they did not want to take part in nucleic acid testing, and also really hoped that the younger generation would additionally attempt not to undertake nucleic acid testing as well as antigen testing.

“The covid test swab is not the same as the cotton swabs used in daily life, but it does not contain reagents, nor is it toxic”. ( Click here to learn more )

What is a flocked swab and why choose flocked oropharyngeal and nasopharyngeal swabs?

A flocked swab is used because it is more suitable for sampling and testing. The flocking swab(learn more) is made of nylon fiber flocking technology, and the front end is coated with nylon short fibers fixed in a vertical manner, so that there is no absorption hole in the entire collection area of the collection swab. In this way, the collected sample is not dispersed and retained in the fiber, which facilitates faster and more efficient elution. Relevant data show that CellMedical flocked swabs can elute more than 95% of the sample collection volume; traditional cotton swabs, especially those made of absorbent cotton, cannot completely collect and elute samples.

Enlarged view of flocked swab

Nasopharyngeal swabs – which require a swab inserted into the nose to collect samples from the back of the nose and throat – are the gold standard for collecting samples for diagnosis. But the process is technically difficult, often uncomfortable for patients, and requires personal protective equipment that may be in short supply.

Oropharyngeal swab – the oropharyngeal swab is a method of collecting oropharyngeal specimens by entering the sampling swab through the mouth – compared with a nasopharyngeal swab, it is less difficult, more acceptable to the public, and more universal.

What exactly is PCR nucleic acid detection?

PCR (Polymerase Domino Effect, polymerase chain reaction) innovation is a wonderful creation, without the creation of PCR modern technology, there would be no modern-day molecular biology. Nucleic acid detection modern technology has likewise entirely transformed several techniques such as genetics, medication, and also forensics, allowing human beings to accomplish significant steps such as hereditary testing, viral infection identification, and also genetic testing.

Basically, PCR nucleic acid detection: To significantly magnify nucleic acid till it can be identified by equipment detection. Yet if you increase the size of the nucleic acid, 1 ends up being 2, 2 comes to be 4, and also 4 ends up being 8. Consequently, PCR innovation is a method of amplifying nucleic acid.

After the covid-19 contaminates the human body, it will initially increase in the respiratory system. So it can be determined whether the body is infected by finding the viral nucleic acid in sputum and nasopharyngeal swabs. After a duration of infection, typically 7-10 days later, the body will certainly create specific antibodies versus the virus. IgM antibodies show up initially, adhered to by IgG antibodies. So immunological discovery approaches can identify these specific antibodies to identify whether the human body is carrying the virus.

Will the results from different nucleic acid testing institutions be consistent?

PCR nucleic acid detection has a strict standard procedure. It is the same SOP (Standard Operation Procedure). At the exact same time, all nucleic acid labs, regardless of dimension, must adhere to the same technological demands, and also the design and building of laboratories additionally have uniform specifications. Also, research laboratory screening staff have to go through standard technical training and also acquire a nationally identified task certification before they can work. It resembles KFC’s fried chicken all use the exact same dish. Whether it’s a fast window in the station, a sizable and comfortable dine-in in the town hall, or home delivery, you can constantly eat deep-fried chicken with the exact same preference, do not fret will certainly strike rumbling.

Therefore, no matter which institution we conduct nucleic acid testing, the outcomes need to coincide.

The collection of samplings from different components has different clinical importance. Along with the popular nasal swabs and throat swabs, sputum, blood as well as rectal swabs；

Nasal and throat swabs – upper respiratory tract specimens

Sputum – Lower Respiratory Tract Specimens ( Saliva Collection Kits )

Anal swab – digestive tract specimen

Blood – Antibody Test Specimen

The distinction between both is a positive nucleic acid shows the presence of viral nucleic acid in the sampling. Which suggests that the infected individual might be infectious. A favourable IgM antibody shows that the patient remains at the beginning of infection. IgG antibodies indicated that the patient had SARS-CoV-2. However, we were unable to determine whether it was transmissible. Compared with antibody detection, PCR nucleic acid discovery is much more sensitive and is additionally the “gold criterion” for laboratory detection.

Therefore, in recent cases, doctors discussed that the patient has symptoms of infection.

What factors may affect COVID-19 nucleic acid test results?

1. Viral load: In summary, when the viral lots are low. False negatives may occur.

2. The coronavirus may alter, which may further impact the accuracy of the test in the future.

3. Testing method: In the recently reported genuine tasting scene, several participants reported that the swab only revolved left and right in the mouth, and it really felt like it was only touching saliva.

However, did not reach the lingual and palatal arc, and the respondents did not have nausea and also reflexes. Sex-related security action, this type of tasting has a high possibility of not gathering exfoliated cells of the respiratory tract, so it is vulnerable to missed discovery, leading to false unfavourable results.

CellMedical VTM Kits Disposable Virus Sampling Tube Manufacturers

Cell medical (Dongguan) Co., Ltd., established in 2009, a swabs design/swabs manufacturer, has many years of experience in medical application moulding and flocking treatment heads and swabs. Our flocking swabs are famous for their stable and reliable performance and excellent absorption and elution ability.

We produce flocked swabs, VTM kits, and virus transport medium, with multiple automatic production lines(Including automatic VTM tube production line, OEM VTM Tube, Flocked Swab Production Line, etc).

Chinese Medical Swab Suppliers Manufacturers

Posted on 2022年5月11日2022年5月11日 by Dr. Lee

Cell medical (Dongguan) Co., Ltd. Flocking sampling Medical Swab manufacturers can be customized according to customer needs.

Cell medical (Dongguan) Co., Ltd. is a comprehensive high-tech medical consumables company and an OEM factory for flocking swabs. We support customized production, our swab OEM factory produces flocking swabs, throat swabs, nasal swabs, oral swabs, sponge swabs, virus sampling tubes, virus transport media, and sample preservation solutions. Our GMP factory was built in 2016, and the factory has an ISO13485 quality management system, CE, FDA and other qualifications.

ABOUT VTM kits and swabs manufacturer

We support ODM and OEM

Our factory has a number of automated production lines. We support customized production, OEM, ODM, etc., and jointly develop and design products with customers. Willing to challenge all kinds of harsh swabs.

Customization of flocking swabs, customization of VTM kits, customization of a virus transfer medium, customization of virus collection and transfer kits, customization of disposable virus sampling tubes, customization of nasopharyngeal swabs, customization of oropharyngeal swabs, etc.

Welcome to the factory for consultation, we will serve customers wholeheartedly and develop high-quality flocked Medical swabs together with customers.

Features of our flocked swabs

Covid Swab Test flocked swab

1. The flocked swab is made of nylon fibre flocking technology, and the sample collection and release amount is as high as 95%;

2. Nylon nails are fixed vertically, the elution speed is faster and the efficiency is higher;

3. Single independent packaging to avoid pollution.

4. Strict process conditions, DNase free and amplifiable human DNA.

5. The tube body is transparent and the inspection material is visible.

6. The unique patented shell design ensures air circulation in the shell and prevents the detection material from becoming mouldy due to the humidity of the sealing environment. It avoids magazine pollution in the outside air and affects the detection quality.

Advantages of our flocked swabs

1. Especially designed for virus sampling and DNA micro-samples. Especially for trace samples such as sweat, semen, blood, dandruff, oral cells, etc., it has excellent collection performance.

2. It can quickly adsorb trace samples and release a high aging rate.

3. Flocked swabs become ideal for PCR work.

4. The front end is more precise and is suitable for cell extraction in the nails of victims or suspects.

5. The unique flocked swab breakpoint design is beneficial to the automatic extraction workstation for sample extraction.

6. Packaged in a clear plastic tube to avoid biological contamination.

Combined Throat And Nose Swab

Posted on 2022年5月10日2022年5月10日 by Dr. Lee

What is the difference between a nasal (Nose) swab and a throat swab for nucleic acid testing

The sampling method and location are different. The accuracy rates of the nucleic acid test ( PCR Test ) nasal swabs and throat swabs are usually similar, and the main difference lies in the sampling method and sampling site. For nasal swabs, nasopharyngeal swabs (flocking swabs) are mainly used to test the secretions from the inside of the nasal cavity and the surface of the nasal mucosa through the nasal cavity;

Throat swabs: Health care workers collect samples in the mouth with oropharyngeal swabs. Health care workers take throat samples for testing to determine whether a patient has the new coronavirus.

Are both throat swabs and nasal(Nose) swabs required?

Let’s talk about throat swabs first.
The “oral sampling” and “nasal sampling” mentioned above are actually test methods in which medical staff use medical swabs to collect samples from the pharynx in nucleic acid testing (PCR).

COVID-19: Will The Pandemic End in 2022?

It is very important to continue swab testing while the pandemic is still ongoing

Whether entering from the nasal cavity or the mouth, the specimens we need to collect are pharyngeal secretions, including sputum. Compared with the oral route, nasal sampling can provide better safety protection for the sampling person. Because oral sampling requires subjects to open their mouths wide, this increases the risk of virus transmission by droplets. However, if it is collected through the nasal cavity, the environment is relatively stable, and the medical staff who operate it will be safer.

What is the difference between a throat swab and a nasopharyngeal swab, which is more accurate?

The main difference between nasal swabs and throat swabs lies in the location and material of the specimens, which are usually as accurate. The throat swab is in the pharynx, and the nasal swab needs to go into the nasal cavity, not the external nasal cavity. It needs to use a longer swab and slowly rotate it to the deep part of the nasal cavity, so the parts of the material are different. Nasal swabs are special, and the material is relatively soft, which is convenient for reaching the deep nasal cavity through the nasal cavity. The process of taking it may take longer than that of throat swabs.

Compared with nasopharyngeal swabs, oropharyngeal swab sampling is sometimes difficult to meet the normative sampling requirements due to irritating reactions, and the actions of eating, drinking and swallowing will reduce the oropharyngeal to a certain extent. The virus enrichment of 2000 may affect the positive detection rate of oropharyngeal swabs.

Which is better, nasal(Nose) swab or throat swab?

No matter which one is adopted, the key lies in the depth of the collection, whether the collection is in place and the length of contact time with the deep mucosa.

From the personal experience of the testing population, throat swabs will be less irritating and uncomfortable than nasal swabs.

Sterile Flocked Swab

Oropharyngeal swab

　　• The operation is relatively simple and less irritating, suitable for large-scale screening.

　　• The sampling staff will guide the subject to open the mouth, and then use a sterile long cotton swab to gently scrape the subject’s throat to collect secretions from both palatine arches, pharynx, and tonsils.

Nasopharyngeal swab

　　• The technical requirements are high, the human body does not feel very comfortable, and the accuracy is higher than that of oropharyngeal swabs. For key groups such as isolation points.

　　• The sampling staff will insert a long sterile cotton swab into the nostril of the subject, and reach the mucous membrane deep in the nasopharyngeal cavity, stay for a few seconds to soak the secretion, and then take it out.

Who is not suitable for nasal swab

What is A Covid-19 NP Swab?

When collecting nasal swab specimens, the flocked swab ( learn more ) will enter the nasal cavity.

f the medical staff operates in a standardized manner, it will reduce the irritation to the mucous membranes.

But because we can’t see the sampling position of the pharynx.

It mainly relies on the hands of medical staff to feel the resistance, so the technical requirements of the operator are very high, and the tools used are also more complicated.
The improper operation will cause certain irritation to the nasal mucosa, so it is not recommended for patients with sinusitis and allergic rhinitis to do nasal swabs to avoid damage to the nasal cavity.

How to overcome the discomfort of throat swab

When collecting throat swab specimens, the oropharyngeal flocked swab will cause certain irritation to the pharynx. For some people with the sensitive pharynx, nausea and vomiting may occur.

Recommended to relax before collecting specimens.

Don’t get too nervous. If you feel discomfort in your throat after collection, you need to eat less spicy, irritating and greasy food, drink more water, eat more vegetables and fruits, and arrange rest appropriately. Generally speaking, it does not take long to return to normal.

Experts said that the study found that the nucleic acid-positive duration of feces or anal swabs of some infected people is longer than that of the upper respiratory tract. Increasing anal swab sampling can improve the detection rate and reduce missed diagnosis; but anal swab sampling is not convenient enough, and currently only for isolation. Points and other key groups to use.

Flocked Swab With Vtm Kits Leading China Manufacturer

Posted on 2022年5月7日2022年5月18日 by Dr. Lee

What are flocked swabs used for?

Flocked swabs are widely used in Covid Test bacteriological sample processing, virological cell culture, DFA testing, rapid and direct testing, enzyme immunoassay testing, polymerase chain reaction and molecular diagnostic-based tests, and forensic identification. Both are ideal.

For throat sampling of respiratory viruses such as influenza, swine flu, bird flu, hand, foot and mouth.

Vtm Kits are used for the collection, transportation and storage of influenza, avian influenza, coronavirus and other virus samples for subsequent extraction and PCR amplification.

After samplers collect virus samples, they usually do not conduct PCR testing at the sample collection site in time.

So the collected virus flocking swab samples need to be transported. The virus itself will rapidly decompose in vitro, affecting subsequent detection. During transport, we need to add a virus preservation solution (virus transport medium).

For different detection purposes, we need to use different virus preservation solutions.

At present, it mainly includes inactivated type and non-inactivated type. In order to meet different detection requirements and different laboratory conditions for virus detection, it is very necessary to use different preservation solutions.

Sterile Flocked Nasopharyngeal Swab, 100% nylon flocked swab that provides exceptional absorption quality.

The principle of flocking swab precipitation.

1. Through the directional friction effect of the fiber layer of the flocked swab, the laboratory operator can complete the cell sample.

The unique structure of the top of this swab can greatly increase the number of samples collected

2. Flocked Swab is ideal for collecting large amounts of cells & rapid elution of the specimens instantly released into the transport medium.

More than 95% sample release rate. Very easy to elute.

3. The capillary movement between the nylon fibres at the top of the flocking swab forms a strong hydraulic pressure for absorbing liquid or cell-like samples.

Why flocked swabs are more beneficial for micro DNA collection.

1. The top of the traditional cotton swab, may even lead to false-negative results of the test.

2. The top of the flocking swab has a unique structure, which can almost completely extract and separate trace DNA, so the flocking swab has more obvious advantages in collecting trace DNA.

Made of non-inhibitory DNA amplification materials. It has been verified that it can be directly amplified by PCR, eliminating the need for extraction steps.

About viral transport media

At present, it mainly includes two types: inactivated and non-inactivated.

Flocked Swab With Vtm Kits Leading China Manufacturer

Inactivated preservation solution:

It can lyse and inactivate the virus in the sample so that the virus loses its infectious activity.

It can effectively prevent the secondary infection of operators.

But it also contains inhibitors, which can protect the viral nucleic acid from degradation.

Therefore, the experimenter can perform follow-up detection by NT-PCR.

Stored at room temperature for a long time, saving the storage and transportation costs of virus samples.

Non-inactivated preservation solution:

The non-inactivated preservation solution of the present invention can maintain the in vitro activity of the virus and the integrity of the antigen and nucleic acid, protect the viral protein shell, and maintain the originality of the virus sample to a large extent.

Not only for nucleic acid extraction and detection (PCR test) but also for virus culture and isolation.

　　The CellMedical virus sampling tube has a thickened and leak-proof design to ensure that the sample does not leak during transportation. It is a virus transport medium (VTM KITS) that complies with WHO regulations and biosafety regulations.

Viral Transport Medium Tube Suppliers

CellMedical produces and sells medical swabs, sampling swabs, sterile swabs, flocking swabs, sponge swabs, nasal swabs, throat swabs, nasopharyngeal swabs, gynecological swabs, genetic swabs, forensic swabs Swabs, oral swabs, nucleic acid swabs, new crown swabs, antigen swabs, anterior nasal swabs, sterilized swabs, collection swabs, flocking cotton swabs, sampling cotton swabs, etc.

Cell medical (Dongguan) Co., Ltd. is a Class II medical device manufacturer integrating R&D, production, sales and service.

The company is committed to providing cells, Virus, Microorganism Collection & Storage & Shipping Solutions.

Cell medical (Dongguan) Co., Ltd. was established in 2009, the company is located in Chang’an, Dongguan.

We mainly produce flocked sampling swabs, sponge sampling swabs, preservation transport media, virus sampling tubes and saliva collectors.

Cell medical (Dongguan) Co., Ltd China Vtm Swab Supplier And Manufacturers

VTM Kit, Viral Transport Media manufacturers, suppliers & exporters in china. Vtm SWAB collection kit compatible with its PCR test

To provide cell, virus, microbial sample collection, storage and transportation solutions for life sciences. Forensic identification, CDC, in vitro diagnostics and medical testing.

After more than 10 years of unremitting efforts and the pursuit of excellence in quality,

Today, CellMedical has become a Class II medical device manufacturer integrating R&D, production, sales and service.

Medical care means high technology and rigour. We always adhere to the concept of “survive by quality and develop by innovation”.

The company has an 8,000-square-meter workshop, a 3,500-square-meter GMP workshop and a 600-square-meter laboratory.

The sterile sampling swabs we produce have a high collection volume and release volume, which greatly enhances the accuracy of the inspection;

Well received by domestic and foreign customers. The company has passed ISO 13485 quality system, and flocking and sponge swabs have product registration certificates, CE and FDA certifications.

ABOUT VTM kits and swabs manufacturer

What is viral transport medium ?

Posted on 2022年5月6日2022年5月6日 by Dr. Lee

Viral transport medium is a protective liquid medium added to the virus sampling tube to protect the samples after nasopharyngeal swab sampling and is usually called virus preservation solution in China.

Usually, in nucleic acid testing (PCR swab test), we cannot perform nucleic acid PCR directly at the sample collection site.

We need to add virus preservation solution (VTM) to the samples collected by swab for transfer check.

Viral Transport Media Kits Manufacturer

What is a virus?

Viruses are microorganisms whose structure is very simple.

There is no way to complete the process of self-replication.

They need the help of host cells and the nutrition of the host to complete virus replication.

The virus can infect humans as well as many other animals.

Influenza viruses such as common infectious diseases are usually RNA viruses.

There are many common viruses that cause human infection, which can cause respiratory diseases, such as cold virus, influenza virus, HIV and influenza A virus.

Since it has no cellular structure of its own, the virus itself cannot replicate.

But invades the gene into the host cell and replicates the new virus with the help of the latter’s replication system.

In conclusion, viruses are diverse and can cause damage to multiple parts of the body. “

After the virus sample is collected, in order to maintain the activity of the virus sample and prolong the survival time of the virus in the sample, the sampling swab ( flocking swab ) will be put into the preservation solution ( viral transport media ) for preservation and transportation.

What is the viral transport medium used for?

PCR test

The inactivated viral transport medium can perform protein denaturation on fresh clinical virus specimens to inactivate the virus. Prevent secondary infection and ensure the safety of transportation and testing personnel. The inactivated samples can be used with a variety of virus extraction kits.

The nucleic acid extraction instrument can quickly extract nucleic acids.

At the same time, with the respiratory pathogen PCR detection kit (VTM Kits) to achieve rapid detection. The specificity and sensitivity are not affected.

Virus preservation solution has many functions:

1. The operation is simple, and the liquid contains ingredients that can denature proteins, thereby inactivating the virus;

2. Contains inhibitors to protect the stability of viral nucleic acid to a greater extent and greatly improve the nucleic acid extraction rate;

3. Stored at room temperature for 12 months before sampling.

The airtightness is good, which is convenient for storage and transportation and saves transportation costs.

Cell medical (Dongguan) Co., Ltd.

Viral transport media include inactivated and non-inactivated viral transport media.

Contains Hank‘s Liquid, Potassium Chloride, Magnesium Chloride, Calcium Chloride, BSA, etc. The combination of various antibiotics has antibacterial and antifungal effects. Bovine serum albumin (BSA), as a protein stabilizer, can form a protective film on the protein shell of the virus. Making it difficult to decompose and ensuring the integrity of the virus; Hank’s buffer The neutral environment constructed by the agent helps to increase the survival time and infection stability of the virus.

What is viral transport medium?

Nasopharyngeal Swab

Inactivated and non-inactivated virus preservation solutions: usually used for the collection and transportation of clinical influenza, avian influenza, hand, foot and mouth virus, measles and other virus specimens, as well as specimens such as mycoplasma, ureaplasma, chlamydia, etc.

1. For monitoring and sampling of infectious pathogenic microorganisms by disease control departments and clinical departments.

It is suitable for a sampling influenza virus (common influenza, highly pathogenic avian influenza, H1N1 influenza virus, etc.), hand, foot and mouth virus and other types of viruses.

2. To transport nasopharyngeal flocked swab specimens or tissue specimens from specific parts from the sampling site to the testing laboratory for PCR extraction and detection.

3. Preserve nasopharyngeal swab samples or tissue samples from specific parts for necessary cell culture.