An abrupt COVID-19 has brought flocking swabs, nasopharyngeal swabs, oropharyngeal swabs, nucleic acids, antigens, PCR and also other extremely professional terms right into the public eye. Today, CellMedical will certainly offer you preferred scientific research: those aspects of Coronavirus (COVID-19) screening.
What is a flocking swab, nasopharyngeal swab, or oropharyngeal swab?
When nations are executing a new round of nucleic acid screening, a report is spreading out in circles. The basic concept is “the cotton bud used for sampling have reagents on them, which are hazardous”. Some netizens also left a message to the CellMedical firm backstage, saying that after seeing the pertinent reports, the elderly at home shared that they did not want to take part in nucleic acid testing, and also really hoped that the younger generation would additionally attempt not to undertake nucleic acid testing as well as antigen testing.
“The covid test swab is not the same as the cotton swabs used in daily life, but it does not contain reagents, nor is it toxic”. ( Click here to learn more )
What is a flocked swab and why choose flocked oropharyngeal and nasopharyngeal swabs?
A flocked swab is used because it is more suitable for sampling and testing. The flocking swab(learn more) is made of nylon fiber flocking technology, and the front end is coated with nylon short fibers fixed in a vertical manner, so that there is no absorption hole in the entire collection area of the collection swab. In this way, the collected sample is not dispersed and retained in the fiber, which facilitates faster and more efficient elution. Relevant data show that CellMedical flocked swabs can elute more than 95% of the sample collection volume; traditional cotton swabs, especially those made of absorbent cotton, cannot completely collect and elute samples.
Enlarged view of flocked swab
Nasopharyngeal swabs – which require a swab inserted into the nose to collect samples from the back of the nose and throat – are the gold standard for collecting samples for diagnosis. But the process is technically difficult, often uncomfortable for patients, and requires personal protective equipment that may be in short supply.
Oropharyngeal swab – the oropharyngeal swab is a method of collecting oropharyngeal specimens by entering the sampling swab through the mouth – compared with a nasopharyngeal swab, it is less difficult, more acceptable to the public, and more universal.
What exactly is PCR nucleic acid detection?
PCR (Polymerase Domino Effect, polymerase chain reaction) innovation is a wonderful creation, without the creation of PCR modern technology, there would be no modern-day molecular biology. Nucleic acid detection modern technology has likewise entirely transformed several techniques such as genetics, medication, and also forensics, allowing human beings to accomplish significant steps such as hereditary testing, viral infection identification, and also genetic testing.
Basically, PCR nucleic acid detection: To significantly magnify nucleic acid till it can be identified by equipment detection. Yet if you increase the size of the nucleic acid, 1 ends up being 2, 2 comes to be 4, and also 4 ends up being 8. Consequently, PCR innovation is a method of amplifying nucleic acid.
After the covid-19 contaminates the human body, it will initially increase in the respiratory system. So it can be determined whether the body is infected by finding the viral nucleic acid in sputum and nasopharyngeal swabs. After a duration of infection, typically 7-10 days later, the body will certainly create specific antibodies versus the virus. IgM antibodies show up initially, adhered to by IgG antibodies. So immunological discovery approaches can identify these specific antibodies to identify whether the human body is carrying the virus.
Will the results from different nucleic acid testing institutions be consistent?
PCR nucleic acid detection has a strict standard procedure. It is the same SOP (Standard Operation Procedure). At the exact same time, all nucleic acid labs, regardless of dimension, must adhere to the same technological demands, and also the design and building of laboratories additionally have uniform specifications. Also, research laboratory screening staff have to go through standard technical training and also acquire a nationally identified task certification before they can work. It resembles KFC’s fried chicken all use the exact same dish. Whether it’s a fast window in the station, a sizable and comfortable dine-in in the town hall, or home delivery, you can constantly eat deep-fried chicken with the exact same preference, do not fret will certainly strike rumbling.
Therefore, no matter which institution we conduct nucleic acid testing, the outcomes need to coincide.
The collection of samplings from different components has different clinical importance. Along with the popular nasal swabs and throat swabs, sputum, blood as well as rectal swabs；
Nasal and throat swabs – upper respiratory tract specimens
Sputum – Lower Respiratory Tract Specimens ( Saliva Collection Kits )
Anal swab – digestive tract specimen
Blood – Antibody Test Specimen
What is the difference between nucleic acid testing and antibody testing?
The distinction between both is a positive nucleic acid shows the presence of viral nucleic acid in the sampling. Which suggests that the infected individual might be infectious. A favourable IgM antibody shows that the patient remains at the beginning of infection. IgG antibodies indicated that the patient had SARS-CoV-2. However, we were unable to determine whether it was transmissible. Compared with antibody detection, PCR nucleic acid discovery is much more sensitive and is additionally the “gold criterion” for laboratory detection.
Therefore, in recent cases, doctors discussed that the patient has symptoms of infection.
What factors may affect COVID-19 nucleic acid test results?
1. Viral load: In summary, when the viral lots are low. False negatives may occur.
2. The coronavirus may alter, which may further impact the accuracy of the test in the future.
3. Testing method: In the recently reported genuine tasting scene, several participants reported that the swab only revolved left and right in the mouth, and it really felt like it was only touching saliva.
However, did not reach the lingual and palatal arc, and the respondents did not have nausea and also reflexes. Sex-related security action, this type of tasting has a high possibility of not gathering exfoliated cells of the respiratory tract, so it is vulnerable to missed discovery, leading to false unfavourable results.
CellMedical VTM Kits Disposable Virus Sampling Tube Manufacturers