Deep Nasal Swab Virus Respiratory Kit

Posted on 2022年4月30日2022年4月30日 by Dr. Lee

As of April 30, local time, the number of new coronavirus patients in the United States has reached 81.2 million, and the number of deaths due to new coronavirus infection has exceeded 992,000.

As the government ramps up testing for Covid-19, many of us ordinary people are now being tested for Covid-19.

What is Deep Nasal Swab?

Deep Nasal Swab ( nasopharyngeal swab ) is actually a relatively long collection swab, similar to a relatively long sterile swab.

Its main function is to take nasopharyngeal secretions for bacterial culture and drug sensitivity tests.

The source of infection in the nasopharynx and the microorganisms in the nasopharynx were selected and identified by bacterial culture and drug sensitivity test.

Then a drug susceptibility test can be done to determine which drugs are sensitive so that sensitive drugs can be selected for treatment.

So that a better curative effect can be achieved, so the nasopharyngeal swab is actually a flocking swab for collecting nasopharyngeal samples.

China Sterile Flocked Nasopharyngeal Swab GMP Factory and Manufacturers.

Why deep nasal swab for covid?

The Deep Nasal Swab test: to collect cells deep in the nasal cavity because the nostrils by themselves do not provide a sufficiently accurate sample.

The collected fluid samples are sent to a laboratory for PCR testing (polymerase chain reaction), a standard scientific procedure that involves using samples provided by patients to build models of their DNA.

In this system, technicians can look for evidence of the genetic material (RNA) from the new coronavirus, which is wrapped in the patient’s own DNA if they are infected with the virus.

Both Public Health England and the US Centers for Disease Control and Prevention (CDC) prefer to use Deep Nasal Swab because it is so accurate.

Unfortunately, for suspected Covid-19 patients, it can be uncomfortable.

During the operation, the medical staff is gentle and skilled, so there will be no pain.

What is the correct depth and length of nasopharyngeal swab collection?

See the length of the nasal swab? See how deep it goes into your nostrils?

The length of the nasal swab is normally about 15cm, and it should enter about 2/3 of the time when doing the collection.

The nasopharyngeal swabbing is generally the preferred method of specimen collection for COVID-19 testing.

About the distance from the tip of the nose to the earlobe, insert a thin cotton swab into the nostril, from the lower nasal passage to the posterior wall of the nasopharynx, and then turn the front to take a sample. The swab will have a significantly insufficient depth of entry. So the posture must be correct.

When the throat swab enters in the direction of the earlobe if it encounters resistance, it needs to adjust the direction, rotates it slightly, and cannot forcefully enter it.

Otherwise, damaged. Until the bottom of the rhinitis is reached, there is a general sense of resistance against a wall.

When you feel a sense of resistance, you have reached the bottom of the nasopharynx. At this time, you need to keep the nasopharyngeal swab at the bottom of the rhinitis for 10-15 seconds. After fully contacting the secretion, rotate it and pull it out.

Deep Nasal Swab Manufacturer Virus Respiratory Kit

Specifically designed for the collection, transport and preservation of virus-containing samples such as influenza, covid-19, avian influenza, and respiratory viruses such as hand, foot and mouth. 2-8 ℃ can be stored and transported for a short time, long-term storage should be at -80 ℃ or below.

Disposable medical sample collection swab, consisting of a plastic rod with and a flocked fibre tip

VTM (non-inactivated version) and VTM-N (inactivated version) are available for selection.

Ready-to-use tear-off packaging, is convenient and quick, to avoid possible cross-contamination during use.

Equipped with a biosafety sample bag, which is convenient for placing samples and paper documents, the transfer is safe and reliable.

Product number

product description

VTM-CM-0403

VTM-CM-0202

VTM-CM-0203

10ml sample transport tube contains 3ml VTM transport medium, 1 sampling swab, 1 biological specimen bag

5ml sample transport tube contains 2ml VTM transport medium, 1 flocked swab for sampling, 1 biological specimen bag

5ml sample transport tube contains 3ml VTM transport medium, 1 sampling swab, 1 biological specimen bag

Sampling swabs include nasopharyngeal swab (Deep Nasal Swab) or oropharyngeal swabs

Disposable Virus Sampling Tube Manufacturers

Posted on 2022年4月29日2022年4月29日 by Dr. Lee

What kind of virus sampling tube do you know? Does the following look like what you know? The following is introduced to you by Disposable Virus Sampling Tube Manufacturers — Cell medical (Dongguan) Co., Ltd.

What is Virus Sampling Tube? When should the virus preservation solution be used?

Disposable Virus Sampling Tube Kits

Virus transport medium, virus preservation solution: a protective liquid medium added to the virus sampling tube to protect the samples after nasopharyngeal swab sampling.

Generally, in the process of nucleic acid detection, we cannot directly conduct nucleic acid PCR experiments at the sample collection site.

If we need to check the samples collected by the flocked swab, we need to add the virus preservation solution.

Why use a virus sampling tube?

First of all, we have to understand what is a virus? Why does it need a virus sampling tube?

virus sampling tube

What is a virus?

Virus: a non-cellular form composed of nucleic acid molecules and proteins.

It lives on parasitic hosts and is an organic species between living and non-living bodies.

It is one end of DNA or RNA wrapped in a protective shell.

Through the mechanism of infection, these simple organisms can use the host’s cellular system to replicate themselves but are unable to grow and replicate independently.

Viruses can infect almost all living organisms with cellular structures.

Virus detection is different from conventional biochemical detection.

The virus itself is a simple microorganism and must be parasitic in living cells.

After sampling, when the virus leaves the host cell, its protein shell and nucleic acid degrade rapidly in the sampling tube.

So that the nucleic acid During the test, it is impossible to determine whether the initially collected sample contains the virus, which is likely to cause false negatives.

A virus delivery medium (virus sampling tube), a general-purpose sampling product: for sampling various virus samples, chlamydia samples, and ureaplasma samples.

Short-term storage and transportation at 2-8°C, and -80°C refrigerator or liquid nitrogen Long-term preservation in the environment.

1. For monitoring and sampling infectious pathogenic microorganisms by disease control departments and clinical departments.

Suitable for influenza virus (common influenza, highly pathogenic avian influenza, influenza A H1N1 virus, etc.), hand, foot and mouth virus and other types of virus sampling. It is also used for sampling Mycoplasma, Chlamydia, Ureaplasma, etc.

2. To transport nasopharyngeal swab specimens or tissue specimens from specific parts from the sampling site to the testing laboratory for extraction and testing.

3. Preserve nasopharyngeal swab samples or tissue samples from specific parts for necessary cell culture.

4. For short-term storage and transportation of virus samples at 2-8°C and long-term storage in a -80°C refrigerators or liquid nitrogen environments.

There are two types of virus preservation solutions: inactivated and non-inactivated

The inactivated virus preservation solution is mainly a virus lysis type preservation solution improved by nucleic acid extraction lysis solution, which is added with a high concentration of lysis salt, which can quickly and efficiently deactivate the virus protein in the sample to be tested and can effectively prevent infection.

At the same time, it also contains an RNase enzyme inhibitor, which can protect virus nucleic acid from degradation.

As long as the subsequent NT-PCR experiment can detect the nucleic acid of the virus, we can diagnose it.

Stored at room temperature for a relatively long time.

The non-inactivated preservation solution is mainly a virus maintenance solution that is improved on the basis of the transport medium.

It can retain the protein coat of the virus and the viral nucleic acid DNA or RNA at the same time so that the virus has the integrity of the protein epitope and nucleic acid in vitro.

Of course, there is also a certain risk of infectivity when the operation is wrong.

It is necessary to keep a strictly low temperature for long-term storage after sampling.

No matter what kind of virus preservation solution it is, we must test it as soon as possible after sampling or keep it strictly at a low temperature to ensure that the detection is accurate.

Due to the rapid reproduction and mutation of the virus, the virus preservation solution plays a crucial role in maintaining the stability of the virus sample.

Manufacturers CellMedical Virus Sampling Tube Kits Advantages

1. Add protein-stabilizing components such as BSA to the sampling solution to reduce the speed of virus decomposition and greatly improve the positive rate of virus isolation.
2. It is stable at room temperature and can keep its activity within 1 year.
3. Gentamicin replaces penicillin to avoid allergic reactions;

4. Using flocked swabs, the sample has a higher collection rate and release rate;
Samples can be stored for a long time (-20 ℃ ordinary refrigerator, -80 ℃ low-temperature refrigerator, -197 ℃ liquid nitrogen);
6. Thickening and anti-leakage design to ensure that the sample does not leak, in line with WHO regulations and biosafety regulations.

Reuse Nasopharyngeal Swabs Disadvantage

Posted on 2022年4月20日2022年4月20日 by Dr. Lee

Nasal swabs reused at an Indonesian airport? What are the dangers of reusing nasal swabs?

Since the epidemic, the term nasal swab testing has entered our lives. Basically, you will be asked to do a nucleic acid test when you are on a business trip or travelling. After the test is completed, the sterile flocked swab will be processed for medical waste. However, news broke out recently that refreshed the three views, and netizens called out “there is no bottom line”!

According to reports, employees of a medical company in Indonesia were found to be repeatedly using sterile nasal swabs when testing airport passengers. At present, more than 9,000 passengers are expected to be affected.

After investigation, the Indonesian police found that the employees involved first performed Nasopharyngeal Swabs tests on passengers with sterile nasal swabs every day, then cleaned the used sterile swabs with alcohol, and then packaged them for use by the next batch of passengers. . This behaviour is outrageous.

Contents of this article

1. What are the dangers of reusing nasal swabs?

2. Why are the swabs for PCR Swab Test put together?

3. What should I pay attention to when doing nucleic acid testing?

4. Will the swabs for nucleic acid testing be reused?

What are the dangers of reusing nasopharyngeal swabs?

The nose is a barometer of human health. When there are lesions in the body, the colour of the snot changes to yellow or green. Nasopharyngeal swabs are a test sampling method to assess the presence of respiratory viral or bacterial infections by collecting samples from the surface of the respiratory mucosa.

As a rule, nasal swabs cannot be reused. If the nasal swab is reused, the consequences will be disastrous.

If the nasal swab is reused, it will increase the risk of virus infection. Previously, a British research team found that two kinds of cells in the nose may be the other infection sites of the new coronavirus. A clinical study found that the viral load of nasal flocked swabs The amount is significantly higher than that of throat swabs. If nasal swabs are reused, it is likely to cause cross-infection and expand the scope of infection.

On the other hand, it may lead to inaccurate test results, false positives or false negatives. It may cause psychological panic and unnecessary treatment to the subjects, and false negatives may mean that the subjects cannot find out that they have been infected in time, miss the best treatment time, and even cause more people to be infected.

Nasopharyngeal flocked swab CellMedical

Why are the sample collection swabs for nucleic acid testing all put together?

This kind of multi-person mixed inspection can improve efficiency and reduce costs.

Mixed sampling testing refers to mixing samples from multiple people (generally no more than 10 people) into the same test tube for testing, improving testing efficiency and reducing testing costs, but the waiting time for centralized sampling may be slightly longer. According to the voluntary principle, the nucleic acid test of all employees can be tested by mixed sampling technology. The laboratory testing time for mixed sample and single-tube testing is the same, which does not affect the time for issuing the testing report.

The so-called five-in-one and ten-in-one mixed sampling detection technology are to put 5 or 10 individual swabs into a collection tube. When the test result is negative, the mixed sample is negative, and the mixed sample is 5 people. or 10 people are safe;

If there is a positive result, the relevant department will be immediately notified to temporarily isolate the 5 or 10 subjects in the mixed tube, take a single tube swab again for the review, and then determine which of the 5 or 10 people is positive.

What should I pay attention to when doing a nucleic acid test (PCR test)?

Pcr test nasal swab and an antigen test difference for covid 19

Today, many people who travel to and from high-risk areas of the epidemic require nucleic acid testing.

So, what should we pay attention to when doing nucleic acid testing (PCR SWAB TEST)?

Before the nucleic acid test: do not eat within 2 hours, do not smoke or drink within 30 minutes, carry a valid ID card, wear a mask correctly, and inform the testing personnel of past medical history or related matters.

When doing nucleic acid testing: Keep a distance of more than 1 meter when queuing, tilt your head slightly, relax, take a deep breath, and have symptoms such as dry cough or sneezing, use a tissue or cover with your arm.

After the nucleic acid test: leave the collection site immediately, and wipe your hands with hand sanitiser or alcohol.

In fact, whether it is a nasopharyngeal swab or a throat swab, it is an effective virus detection method. Although there will be slight discomfort during the test, it will soon return to normal and will not affect your health. Therefore, if necessary, we must actively cooperate with nucleic acid testing, which is responsible for ourselves and others.

Nucleic acid detection: For virus detection method.

It uses a collection flocked swab to collect a sample from the throat or nose of the tester and then conducts the test to obtain the final result.

Some people found that the flocked swabs for nucleic acid testing will be placed in a bottle(VTM Tube).

This is a mixed test, and most of them occur during nucleic acid testing of all staff, which will not affect the detection effect.

Will the swabs for nucleic acid testing be reused?

Prohibition reused.

In addition to sampling, reagents and other factors, the subject’s own reasons may also lead to “false negatives”.

Not to eat for two hours before the nucleic acid test, not to drink water for the first 30 minutes. And not to smoke, drink water or chew gum to reduce behaviours that may interfere with the test results.

There are other influencing factors before sampling and testing,

1. Please do not take antibiotics a few days before the nasal swab.

2. Do not use disinfectant mouthwash or smear on the affected area a few hours before the nasal swab.

3. Do not eat, smoke, or drink for a few hours before the nasal swab.

China Vtm Swab Supplier And Manufacturers

Posted on 2022年4月16日2022年4月16日 by Dr. Lee

China Vtm Swab Supplier And Manufacturers

As a major producer of anti-epidemic materials, China has supplied a large number of urgently-needed materials to countries around the world during the COVID-19 outbreak, making important contributions to global epidemic prevention and control.

Cell medical (Dongguan) Co., Ltd, is a comprehensive high-tech biotechnology company in Chang’an Town, Dongguan City, Guangdong Province. Daily production large number of flocked sampling swabs, “disposable virus sampling tubes”, and “virus transport media” VTM kits” help prevent the epidemic control.

CellMedical is a high-tech biotechnology enterprise, dedicated to the research and development, production and sales of nucleic acid testing, molecular diagnosis, medical testing, virus testing and other medical device products.

Cell medical (Dongguan) Co., Ltd China Vtm Swab Supplier And Manufacturers

Products independently developed by CellMedical.

The company’s independent research and development products include disposable virus sampling tubes, and disposable sampling flocking swabs. Medical cotton swab. Cell preservation solution, virus transport medium, saliva collection device. Transport medium, virus transport medium, single-use sampler, Sample preservation solution. Vtm swab, vtm tube, nucleic acid extraction reagent, gene detection reagent, new coronary pneumonia detection reagent and other products.

What is a virus sampling swab kit?

Covid VTM Swab Test

The virus sampling swab set is a virus sampling and transfer product for virus nucleic acid detection.

It generally consists of a sampling swab, a sampling tube and a virus preservation solution.

For the nasopharyngeal and oropharyngeal new coronavirus sampling swab sets.

Also known as virus transport medium (Viral Transport Medium), referred to as VTM.

According to the composition and function of virus preservation solution, it includes non-inactivated and inactivated types.

The purpose of the single-use virus sampling tube:

Viral Transport Medium With Swab

The single-use virus transport medium with tube is our company’s best-selling star product. It is suitable for the collection and transfer storage of various influenza viruses, clinical new coronaviruses, influenza, measles and other virus samples. nucleic acid extraction and later virus isolation.

It is also suitable for collecting and transporting specimens such as Chlamydia, Mycoplasma, and Ureaplasma urealyticum.

Specimens are usually collected from the oral cavity, throat, nasopharynx, anus, and other human body parts.

Combination features of our single-use virus sampling tube kits (vtm swab kits):

Disposable virus sampling tubes include sampling swabs and sampling tubes (vtm kits).

Test Sample Collection Vtm Kit

1. Sampling flocking swab: our company uses a nylon flocking swab (vtm swab). Because nylon flocking has no toxic effect on microorganisms and viruses and does not contain RNase and DNase.

It can maximize the collection and release of virus samples and ensure the accuracy of PCR test results.

The flocked swab rod: ABS material, with a unique breakpoint design.

Convenient to put into the sampling tube without contamination.

2. Virus sampling tube: The tube body and tube cover are made of polypropylene, which will not deform at high temperature and high pressure (121°C, 15min). And will not become brittle at low temperatures (-196°C).

Resistant to static extrusion and dynamic impact.

The bottom cone design is resistant to centrifugation and shock.

They are packed with a transport medium (inactivated type, preserved type) for the release and preservation of samples to prevent leakage.

The sampling tube has built-in magnetic beads, which are convenient for elution and facilitate the release of more viruses into the virus transport medium.

Before the higher positive rate of PCR detection, the storage solution in the virus sampling tube was Hank’s solution.

Now, the virus sampling tube preservation solution has been upgraded to CellMedical virus preservation solution.

(that is, UTM, recommended by the World Health Organization and the National Influenza Center of China.)

Based on hank’s solution, BSA, HEPES, amino acids, glycerin and other ingredients. A high PCR test is positive.

Virus preservation solution includes non-inactivated virus transport medium and inactivated virus

In the non-inactivated COVID-19 sampling swab set, the components of the virus preservation solution usually include nutrients (such as salts, proteins, glucose), bacteriostatic agents, buffers, phenol red indicator, etc. required for the survival of the virus.

This virus preservation solution can maintain the activity of the virus to the greatest extent.

Not only for virus detection but also for virus culture and isolation.

In the inactivated new coronavirus sampling swab kit, the components of the virus preservation solution usually include buffers, virus lysing agents (usually guanidines), surfactants, etc.

This preservation solution can directly lyse the virus to release nucleic acid, which is convenient for subsequent nucleic acid detection.

China Vtm Swab Supplier

We are a well-known professional manufacturer of medical sampling and preservation products.

Our company has a number of patents.

Mainly used in genetic testing, biopharmaceuticals, large-scale A-level hospitals, entry-exit inspection and quarantine, diagnostic reagents, CDC, public security criminal investigation, forensic identification and other medical institutions.

vtm swab kits feature

Safety: Contains virus inactivator efficacy to ensure no risk of leakage and infection.
Functionality: Inactivate the virus while protecting the activity of viral RNA and protein, which can be used for viral nucleic acid detection, antigen detection, IgM, IgG antibody detection,) (other products that only preserve RNA are used for viral nucleic acid detection);
Effectiveness: Equipped with a special virus sampling flocked swab, the virus release rate is more than 95% (more than 3 times higher than ordinary cotton swabs).
Stability: It can be effectively stored for 144 hours at 2-8℃, which is convenient for transportation and mailing.
Versatility: Applicable to various viruses such as new coronavirus, influenza, HPV, hand, foot and mouth disease, measles, etc.

Viral Transport Medium With Swab

Posted on 2022年4月14日2022年4月14日 by Dr. Lee

Viral transport medium with swab

The COVID-19 outbreak is expected to have a significant impact on the tedious market for swabs and virus transport media owing to the increasing patient demand for infection diagnosis.

Flocked Swab and viral transport media are expected to grow due to intensive testing of COVID-19 in research institutions and laboratories.

Rising research and development activities to produce COVID-19 vaccines are expected to drive market growth during the pandemic.

The rising number of COVID-19 cases in the global population is expected to drive market growth.

The need to develop vaccines and early diagnostics to treat infections is expected to boost the market growth.

Manufacturing of Viral Transport Medium

Virus sampling tubes are medical device products. The virus sampling tube consists of a sampling flocking swab, virus transport medium and outer packaging. Since there is no unified national standard or industry standard, the products of various manufacturers vary greatly.

CellMedical manufactures viral transport media (VTM) following WHO and CDC recommendations, with or without swabs.

Flocked swab+tube with Viral transport medium

1. Sampling swab:

Virus sample collection flocked swab

The specimen collection swab directly contacts the sampling site, and the material of the sampling head is closely related to the subsequent detection.

　　Synthetic fibres such as PE synthetic fibers, polyester fibres, polypropylene fibers, and rayon fibres should be used for the manufacture of sampling swab tips.

　　(1) Natural fibers such as cotton are not recommended

　　Because the fiber of cotton has strong adsorption of protein, it is not easy to be eluted into the subsequent preservation solution;

　　(2) Nylon fibers are also not recommended

　　Because nylon fibers (similar to toothbrush heads) have poor water absorption, the sampling volume is insufficient and the detection rate is affected.

　(3) Do not use calcium alginate sponges or wooden stick swabs (including bamboo sticks) for the head of the sampling swab.

　　Because the broken wooden sticks or bamboo sticks containing calcium alginate and wooden components will also adsorb proteins after being soaked in the preservation solution, and even have an inhibitory effect on the subsequent PCR reaction.

Flocked swabs manufacturers

Features of CellMedical Flocked Swabs:

1. Has extraordinary adsorption energy.

2. It has a release rate of more than 95% for the collected specimens, thus ensuring a high degree of reliability of the results;

3. There is a unique breakable design on the plastic rod, which is convenient for specimen transportation;

4. Sterilized by ethylene oxide or irradiation, individually packaged;

Nasopharyngeal and oropharyngeal swabs. learn more

2. Virus preservation solution (virus transport medium): There are mainly two kinds of virus preservation solutions widely used in the market, one is a virus maintenance solution improved based on the transport medium, and the other is an improved nucleic acid extraction lysate. Preservation solution.

3. Virus sampling tube: The material of the storage tube should be selected carefully. Some data suggest that polypropylene (Polypropylene) is related to the adsorption of nucleic acids, especially at high tension ion concentration, polyethylene plastic (Polyethylene) than polypropylene (Polypropylene) Easier to grab DNA/RNA. In addition, when using breakable swabs, the storage tube should try to choose a container with a height of more than 8 cm to prevent the contents from splashing and contaminating when the swab is broken.

Virus Sampling Tube

4. Water for production of preservation solution: Ultrapure water used for the production of preservation solution should be filtered by an ultrafiltration membrane with a molecular weight of 13,000 to ensure the removal of biologically derived polymer impurities, such as RNase, DNase and endotoxin, and ordinary purification is not recommended. water or distilled water.

About the use of virus sampling tubes

Sampling using virus sampling tubes is mainly divided into oropharyngeal sampling and nasopharyngeal sampling:

1. Oropharyngeal swab sampling:

first press the tongue with a tongue depressor, then insert the head of the sampling swab into the throat to wipe the bilateral pharyngeal tonsils and posterior pharyngeal wall, and wipe the posterior pharyngeal wall with mild force, avoiding touching the tongue department.

2. Nasopharyngeal swab sampling:

measure the distance from the tip of the nose to the earlobe with a swab and mark it with your fingers, insert the sampling swab into the nasal cavity in the direction perpendicular to the nose (face), and the swab should be inserted at least half the length from the earlobe to the tip of the nose. Leave the swab in the nose for 15-30 seconds, swirl gently 3-5 times, and withdraw the swab.

It is not difficult to see from the method of use, whether it is an oropharyngeal swab or a nasopharyngeal swab, sampling is a technical task, which is difficult and easy to contaminate. The quality of the collected samples is directly related to the subsequent testing. If the viral load of the collected samples Low, easy to cause false negatives, difficult to diagnose.

Most of the samples recommended by the kits currently on the market are oropharyngeal swabs or nasopharyngeal swabs and bronchoalveolar lavage fluid. This can greatly reduce the difficulty of the samplers’ work. After all, it is not difficult to collect venous blood samples, and like the detection of hepatitis C RNA, about 5 ml of EDTA anticoagulated blood samples are separated into plasma, and the extracted and purified RNA can fully meet the needs of PCR detection.

Preservation solution features:

Our independent research and development and production, unique cell preservation technology, can be stored at room temperature for more than 3 years after sampling! No need to refrigerate, store and transport at room temperature.

Viral Transport Medium With Swab Factory

By Type

Swab Type
	Nasopharyngeal swab
	Throat swab

Transmission medium

By Application
		Coronavirus disease
		influenza
		herpes simplex virus
		other

By end-user
		Hospitals and Clinics
		diagnostic laboratory
		other

geography

North America
	The U.S.
	Canada
	Mexico

Europe
	Germany
	The U.K.
	France
	Italy
	Spain
	Rest of Europe

Asia Pacific
	China
	Japan
	India
	Australia
	South Korea
	Rest of Asia Pacific

The Middle East and Africa
	GCC
	South Africa
	Rest of the Middle East and Africa

South America
	Brazil
	Argentina
	Rest of South America

China Nasal Swab Manufacturing

Posted on 2022年4月9日2022年4月9日 by Dr. Lee

Swab manufacturers & suppliers

Nasopharyngeal swabs are suitable for collecting and transporting virus specimens such as covid-19, clinical influenza, avian influenza, hand, foot and mouth disease, and measles, as well as specimens of chlamydia and mycoplasma.

In order to respond to this round of the epidemic, stop the spread of the virus and reduce the risk of infection.

At present, we have successively carried out multiple rounds of swab testing for the new coronavirus.

Why are oropharyngeal swabs and nasopharyngeal swabs performed in covid swab testing?

covid flocked swab

Nasopharyngeal swab refers to the collection of secretions from the throat or nose of a patient with a specialized sterile flocked swab.

We generally use nasopharyngeal swabs to detect viral nucleic acids, viral antigens, and bacterial cultures.

The collection site of the oropharyngeal swab should be the pharynx and tonsils.

The basic steps of collecting the pharyngeal swab are to tilt the patient’s head back, open the mouth wide, and remove the secretions on the surface of the nasal cavity.

The sampler fixed the tongue with a tongue depressor and used polyester or calcium alginate test paper to cross the base of the tongue.

Wiped the posterior pharyngeal wall and the lateral wall of the tonsillar recess 3-to 5 times to collect mucosal cells.

Remove the swab gently, avoiding contact with the tongue, uvula, oral mucosa, and saliva, and insert the swab back into the sampling device or a suitable transport device.

Nasopharynx swab vs oropharyngeal swab

The main difference between the two lies in the sampling method and sampling location.

The detection rate and accuracy of nasopharyngeal swabs are higher than those of oropharyngeal swabs.

Still, nasopharyngeal swabs are more complicated and difficult to operate, and people with nasal diseases。

Such as rhinitis and nasal polyps will not easily adapt, Bleeding may occur during the collection process, so the collection speed is slow.

Compared with nasopharyngeal swabs, oropharyngeal swabs are fast, simple and easy to collect.

And the detection rate can meet the requirements.

Therefore, oropharyngeal swabs are often used in large-scale screening.

For key groups or middle- and high-risk groups.

Required to collect nasopharyngeal swabs, or even stool and blood samples.

In addition to nasopharyngeal swabs and oropharyngeal swabs.

There are also detection methods such as serum, anal swabs, deep cough sputum, nasopharyngeal or respiratory tract extracts, and bronchial lavage fluid.

In general, the method of sample collection will be determined according to different populations and different needs.

China Nasal Swab Manufacturer – CellMedical Company.

We produce flocked swabs, VTM kits, viral transport medium, production line

Nasopharyngeal swab factories, Cell medical is a professional manufacturer of sampling flocked swabs and disposable virus sampling tubes (viral transport medium).

The factory is located in Dongguan, China, with a daily production capacity of more than 1 million sets, aseptic filling technology and aseptic swab production technology.

Nasopharyngeal Nylon Flocked Swab supplier

Sterile Nasal Swab Wholesale

Cell medical (Dongguan) Co., Ltd., a professional VTM kits and swabs manufacturer, and disposable swab tubes exporter, has many years of experience in medical application molding and flocking treatment heads and swabs.

Our flocking swabs are famous for their stable and reliable performance and excellent absorption and elution ability.

We support custom production, OEM and so on, and develop products with customers.

Our factory is our customer’s factory.

Email:flockedswab@swabmanufacturer.com

How To Do Covid Swab

Posted on 2022年3月30日2022年3月30日 by Dr. Lee

Covid Swab testing include nasopharyngeal swabs and oropharyngeal swabs.

A sample taken by a doctor from a patient’s nasal cavity via a nasopharyngeal swab to test for Covid-19.

The oropharynx refers to the detection of secretions mainly from the soft palate, tonsils and other parts of the patient.

We need to pay attention to protection for nucleic acid testing.

The advantage of nasopharyngeal swabs over oropharyngeal swabs is that they are easy to operate.

The operator can stand behind the patient’s side, with only the nostrils exposed, without looking directly into the patient’s mouth.

There is basically no gag reflex, and the exposure risk of the sampler is lower than that of nasopharyngeal swabs.

How to do a covid nasopharyngeal swab without pain?

Since the flocked swab sampling is from the lower nasal passage all the way to the bottom of the nasopharynx.

It is more painful to perform, but in this process, the more nervous and conflicted, the more uncomfortable it will be during sampling.

Therefore, when doing a nasal swab, recommended to relax a little, then tilt your head back, keep still.

And use your nose to inhale and exhale through your mouth.

The collector will make this process quick and generally not too painful.

Does nasopharyngeal swab bleeding affect test results?

It will not affect.

Bleeding when taking a nasal swab is due to the rupture of capillaries in the nasal mucosa when the specimen is taken.

However, under normal circumstances, as long as the secretions from the nasopharynx are collected.

A small amount of bleeding will generally not affect the test results. have an impact.

However, if the secretions from the nasopharynx are not collected during the bleeding.

It is necessary to resample the nasal cavity on the other side after stopping the bleeding by resting.

Therefore, when doing a nasal swab, it is recommended to relax and listen to the collector.

So that sampling can be completed quickly.

Which is more accurate, nasal swab or throat swab?

It has been reported in the literature that when taking samples for SARS-CoV-2 virus nucleic acid detection, the results obtained by simultaneously sampling throat swabs and nasal swabs are generally equivalent.

Therefore, for a nasopharyngeal swab and pharyngeal swab, there is no special regulation on which one to do. It is recommended that those who need to do sampling can choose according to their own conditions. If they can tolerate pharyngeal swab collection, they can do pharyngeal sampling. After the nasal swab was collected, a nasal sampling was performed.

Can nasopharyngeal swab be made by themselves？

Not.

Since the nasal swab test needs to insert the swab deep into the nasal cavity to collect samples, there may be adverse reactions such as pain, gag reflex, tearing, and even nosebleeds during the process, causing physical discomfort and psychological discomfort to the collected person. The sense of resistance will be very strong, so there are highly professional requirements for the sampling personnel, and they cannot be done by themselves.

What Is Specimen Collection ?

Posted on 2022年3月29日2022年3月29日 by Dr. Lee

The surge of covid-19 has seriously affected our life and production.

With the efforts of most scientific researchers, the test of this virus came out.

Collection methods of common virological test specimens.

Nasal Swab Virus Sampling Kits

1. Draw 5 ml of blood for serological examination without anticoagulation

2. Extract cerebrospinal fluid through an aseptic procedure, place it in a sterile test tube, and immediately send it for examination in an ice bath.

3. Take a cervical or vaginal swab to take the secretions from the lesion site.

If there is no lesion site, clean the mucus of the cervical mouth, stick the swab about 1 cm into the cervix and hold it for more than 5 seconds to take it out. And put the swab in the transport solution on the ice at 4 °C.

4. Fecal specimens Take 2g~4g of stool specimens in a sterile container, add 8ml~10ml of transport fluid, and send them for inspection immediately.

5. Gargle solution: The patient can get it by gagling with sterile normal saline several times. After mixing the same amount with the transport solution, send it for inspection immediately.

6. Throat swab: Use a tongue depressor to fully expose the throat to avoid saliva contamination. Use a swabened moist with normal saline to collect specimens on the surface of the throat, and place them in transport fluid for inspection.

7. Nasopharyngeal swab: Take nasopharyngeal secretions for bacterial culture and drug sensitivity test.

7. Urethral swabs and urine specimens. The tester inserts the urethral swab 4 cm into the urethra and rotates it gently 2 to 3 times to obtain more epithelial cells. Then take it out and send it to the transport fluid for inspection.

The classification of new coronavirus nucleic acid samples includes nasopharyngeal swabs, oropharyngeal swabs and anal swabs. Different specimens use different methods for specimen collection.

What is a Specimen Collection Kit?

Viral Transport Kit: for collecting, handling, and transporting specimens suspected of VIRUS.

Generally equipped with a disposable flocking swab. From the appearance point of view, the flocking swab is white and soft. Using this soft brush during the sampling process will make the user feel no foreign body, and it is suitable for sampling in different parts. people.

Virus sampling tube: When collecting samples, routine samples could not be detected by PCR immediately. It is generally necessary to transport the swab sample with the specimen. The virus itself dissolves rapidly in vitro, affecting subsequent experiments. For transport, viral transport medium must be added.

What is the Specimen Collection Kit used for?

The nasopharyngeal swabbing is generally the preferred method of specimen collection for COVID-19 testing.

1. Disposable virus sampling tube is used for monitoring and sampling infectious pathogenic microorganisms in the disease control part and clinical part. Suitable for sampling influenza virus (common influenza, highly pathogenic avian influenza, H1N1 influenza virus, etc.). Hand, foot and mouth disease virus and other types of viruses.

It can also be used for sampling other respiratory diseases such as Mycoplasma and Chlamydia. COVID-19.

2. For transporting nasopharyngeal swab samples or site-specific scheduled samples from the sampling point to a testing laboratory for extraction and testing by polymerase chain reaction.

3. For the preservation of nasopharyngeal swab samples or samples arranged at specific sites for necessary cell culture.

Swab in specimen collection

1. Swabs with polyester fibre, polyester or rayon head and plastic or aluminium handle: suitable for the collection of virological test specimens. The collection of virological test specimens should not use swabs with wooden handles.
2. Cotton swabs: It is suitable for the collection of vaginal, cervical and urethral specimens for the mycoplasma test. It is not suitable for the collection of bacteria (especially fastidious bacteria) and chlamydia test specimens.
3. Polyester swabs and nylon swabs: suitable for a sampling of virus and bacterial specimens.
4. Flocked swab: It is made of nylon fiber through proprietary spray technology, and is suitable for respiratory virus sampling and fungal culture specimen sampling.
5. Calcium alginate swab: suitable for the collection of nasopharyngeal swabs for Chlamydia and Bordetella pertussis.

However, it is not suitable for the sampling of lipid-enveloped virus and cell culture. It is not suitable for the sampling of Neisseria gonorrhoeae and Ureaplasma urealyticum.

What Is Virus Transport Medium

Posted on 2022年3月28日2022年3月28日 by Dr. Lee

The virus transport medium is novel and unfamiliar to many small partners, but it is of great significance for the detection of various viruses.

The new crown virus has tortured human beings enough.

In the face of a large number of COVID-19 patients, some places are still rising.

Therefore, as soon as there are new additions, many places will focus on the new crown nucleic acid detection.

The virus preservation solution plays a very important role.

Virus Transport Medium with Specimen collection swab

At present, the nucleic acid detection of the new coronavirus is mainly the detection of viral nucleic acid.

Virus transmission medium is a cell preservation liquid, which protects the virus to be detected by immersing the flocked swab head with the virus sample into the transport tube.

It is mainly suitable for the new coronavirus, Collection, preservation and transportation of common virus samples such as the influenza virus.

To collect throat swabs, nasal swab or tissue samples from specific parts.

The stored samples: for subsequent nucleic acid detection or clinical experiments such as virus culture.

Since the virus is a parasitic organism, it cannot survive outside the body after sampling.

If it cannot be detected in time, it needs to be placed in a virus preservation solution for preservation. (Virus Transport Medium)

In order to protect the safety of the virus detection environment and the safety of the detection personnel, inactivated virus preservation solution is actually a better choice!

FLOCKED SWAB

For different detection purposes, we need to use different virus preservation solutions for preservation.

The two widely used preservation solutions have their own characteristics.

In order to meet different detection requirements and different experimental conditions for virus detection, it is necessary to use different preservation solutions.

The inactivated virus preservation solution can inactivate the virus.

How to detect it after inactivation?

The purpose of our use of inactivated preservation solution is to lyse nucleic acids, release nucleic acids and then carry out nucleic acid detection by subsequent real-time fluorescent RT-PCR.

Doctors use inactivated virus transport media to determine whether the sample contains virus characteristic nucleic acid, that is, whether we carry the virus.

Inactivated virus transport medium:

A virus lysis type preservation solution improved by nucleic acid extraction lysis solution.

Effectively prevent the secondary infection of the operator, but it also contains inhibitors, which can protect the viral nucleic acid from being degraded.

This enables subsequent detection by NT-PCR.

Moreover, stored at room temperature for a relatively long time, which saves the cost of virus sample storage and transportation.

Non-inactivated virus transport medium:

A virus maintenance liquid type preservation solution improved on the basis of the transport medium.

It maintains the activity of the virus in vitro and the integrity of antigens and nucleic acids.

The protective viral protein shell makes it difficult to decompose and maintains the originality of the virus sample to a great extent.

For nucleic acid extraction and detection, the experimenters also use the transport medium for virus culture and isolation and maintain the activity of virus samples.

In addition to nucleic acid extraction and detection, the inspector also uses this preservation solution for virus culture, isolation and antigen detection.

Viral transport media for COVID-19 testing

Posted on 2022年3月25日2022年3月25日 by Dr. Lee

At present, medical technology needs to promote positive energy!

The current epidemic has come and gone.

In particular, important medical materials such as disposable virus sampling tubes (virus transport media) play a key role.

At present, the quality of the products of various manufacturers on the market is also uneven, and there is also a risk of affecting the accuracy of the experimental results.

Make products with a realistic and rigorous scientific attitude;

Let the front-line medical staff have no worries, and provide them with a steady stream of “cannonballs”.

Below we will define the virus delivery medium and explain typical components and options for use.

What is a virus transport medium?

10ml Viral Transport Medium VTM Swab Tube Kit

It is suitable for the collection of various influenza viruses, avian influenza viruses, COVID-19 novel coronavirus, hand, foot and mouth virus samples.

Realize the lysis and inactivation of the virus in the sample.

At the same time effectively ensure the stability of the viral nucleic acid in the sample during storage and transportation at room temperature.

And collect the sample for subsequent PCR analysis and detection.

Features:

✳ Room temperature stable storage;

After use, Stored at room temperature for 7 days, which is conducive to the collection and transportation of samples.

✳ Quick release

Using swabs to collect samples is conducive to subsequent nucleic acid release.

✳ Safe and rapid inactivation of virus samples

The preservation solution can quickly inactivate virus samples, effectively reducing the level of biosafety requirements for sample transportation and subsequent testing laboratories.

✳ Swab breakpoint design

After sampling, the designed rod breakpoint design can easily break the head and save it in the tube.

What are the components of the viral transport medium?

The sample transport medium, viral transport medium (VTM), stabilizes cells and viruses in potentially infected patient samples during transport from the point of collection to the testing facility.

These reagents are suitable for various types of viruses, including coronaviruses, herpes viruses, and influenza viruses.

CellMedical’s products for sample transport include viral transport media and saline solutions, which are both efficient collection and transport media for subsequent qPCR assays.

All sample transfer media are manufactured in a state-of-the-art GMP facility certified to ISO 13485:2016.

UTM Tube with NP Flocked Flexible Swab

1. Virus sampling tube;

Some data suggest that polypropylene (Polypropylene) is related to the adsorption of nucleic acids, especially at high tension ion concentration, polyethylene plastic (Polyethylene) is easier than polypropylene (Polypropylene) to grasp DNA/ RNA.

In addition, when using breakable swabs, the storage tube should try to choose a container with a height of more than 8 cm to prevent the contents from splashing.

Some tubes may be formulated to contain buffered proteins and antibiotics to inhibit the growth of potentially contaminating bacteria and fungi.

2. Virus Transport Media;

VTM consists of Hanks Balanced Salt, Foetal Bovine Product, anti-bacterial prescription antibiotics, anti-fungal anti-biotics as well as Phenol Red as an indication for real-time surveillance of pH security of the service.

3. Collection of flocked swab;

The sampling swab directly contacts the sampling site, and the material of the sampling head is closely related to the subsequent detection.

Sampling swab tips should be made of Polyester (PE) synthetic fibers or Rayon (man-made fibers).

Prohibit calcium alginate sponges or wooden stick swabs (including bamboo sticks).

For example, the material of the swab tip cannot be cotton.

Products, because cotton fibers have strong adsorption of protein.

It is not easy to be eluted into the subsequent preservation solution.

Our flocked swabs are famous for their stable and reliable performance and excellent absorption and elution ability.

Viral transport media applications

The virus sampling tube is a complete set of centrifuge tubes for sampling and transporting viruses such as influenza virus, hand, foot and mouth virus, covid test, etc. in the microbial sampling transport tube, also known as the specimen transport tube.

In the current epidemic, virus sampling is also an important part. Generally, viruses exist in large quantities in the nasopharynx of the human body.

The pharyngeal tester collects virus samples from the nasopharynx and puts them in a virus sampling tube.