Home » Rapid Antigen Nasal Saliva Test

China Saliva Sample Collection Kit Manufacturers

Posted on 2022年5月25日2022年6月1日 by Dr. Lee

The saliva collector is suitable for collecting and storing saliva and cell DNA at room temperature. It can be stored stably at room temperature for more than 2 years. The preserved saliva can be subsequently used for DNA extraction and purification.
The saliva collector can be used for genetic testing and other purposes. By extracting the cellular DNA in the saliva, analyzing the nucleotide sequence of the DNA, determining the gene type, and guiding healthy life.
Saliva collection is non-invasive and painless and can be used for people of all ages, including the elderly and infants.
In the 15-30 minutes before collecting saliva DNA samples, generally do not eat snacks, drink tea, drink alcohol, drink beverages, smoke, chew gum, etc. Before collecting saliva, please relax your facial muscles and gently rub your cheeks for about 1 minute to facilitate the production of saliva and also promote the shedding of oral mucosal epithelial cells. At this point, collect saliva into a saliva collection tube.

Saliva collection method:

China Saliva Sample Collection Kit Manufacturers

30 minutes before sample collection, rinse your mouth with water and fast after rinsing;
Step 1: Install the collection funnel on the collection tube, and spit saliva into the collection funnel until the saliva reaches the filling line of the collection tube.
Step 2: Hold the collection tube vertically with one finger, and close the funnel lid firmly with one hand. The cell preservation solution in the lid will be automatically released into the collection tube and mixed with saliva.
Step 3: Hold the collection tube vertically and rotate gently to separate it from the collection funnel.
Step 4: After screwing on the cap of the collection tube, shake it gently for 5 seconds before use for detection or storage at room temperature.

Part 5: The collection is complete.

The saliva collection device is also called a saliva collector (saliva collector, saliva collection tube, oral sampling tube). The most convenient sampling method for genetic testing is saliva, followed by blood. Currently, the most popular method is to collect saliva samples for testing. , Compared with blood collection, saliva collection is more convenient and free, and the user's acceptance is also higher.

【Features】

Simple: the collection process is simple, fast and easy to operate;

Flexible: easy collection in the laboratory, outpatient clinic, or even at home;

Convenience: the collected saliva is stable and can be stored at room temperature for easy transportation;

Wide range: especially suitable for children and patients who are not eligible for blood sample collection;

Safety: a non-invasive collection of samples, reducing the chance of infection;

Efficient: Sample processing facilitates automated purification, resulting in higher quantities and better quality DNA.

What is an Antigen Covid Test?

Posted on 2022年3月15日2022年3月15日 by Dr. Lee

Antigen Covid Test

We routinely test the nucleic acid with nasal swabs in the department every week, and we have been used to it for several months.

At most, it will pass with a tear and clenched teeth (naive).

So when I was queuing, I didn’t think there was anything to do mentally, and I didn’t notice that the head nurse was training a new little nurse how to do nucleic acid today‼ ️

As a result, it was my turn, and as soon as I sat down, I heard the head nurse say, “I’ll show you one.”

So before she could react, she stabbed in at once, and that feeling, I have never felt so uncomfortable in my life, from nostrils to throats.

It felt like my head was split open, and tears came out. The nasal swab is about 15cm long. According to my classmates, there are only 2cm left.

And because I was so overreacting (yelling and leaning back so fast), the head nurse was so startled that I didn’t have time to pull it out.

The covid flocked swab didn’t come out even after she let go, and I pulled it out with tears.

Many Americans are familiar with the rapid antigen test for COVID-19, which involves swabbing the nose.

What is an antigen test? Can it replace nucleic acid detection (PCR swab test)?

What is an antigen test?

The new coronavirus antigen detection is detected on a test strip through the binding reaction of antigen and antibody.

which is convenient and quick, and the result is usually available in 15-20 minutes.

However, due to the existence of some interference, the antigen-antibody reaction may be falsely positive.

The specificity of the method is less than 100%.

Therefore, antigen test results cannot replace nucleic acid test results.

There are three main methods to detect whether the virus invades the human body: nucleic acid detection (PCR), antigen detection and antibody detection.

The first two are methods of direct detection of viruses.

Compared with nucleic acid detection, antigen detection can be faster and more convenient to operate.

But with lower accuracy, generally used in the initial stage of infection.

After the outbreak, many countries, while recognizing nucleic acid testing as the “gold standard” for COVID-19 testing, have also promoted antigen testing as an effective supplement.

Antigen-positive results can be used for early triage and rapid management of suspected populations.

1. Why do I need an antigen test?

Facilitates “early detection” The new coronavirus mainly has four structural proteins.

Compared with nucleic acid detection, antigen detection is faster and more convenient to operate, and some reagents can produce results in 15 minutes.

Faster and more accurate epidemic prevention and control requires additional antigen testing as a supplement.

Once the antigen test is positive, we need to carry out nucleic acid testing to confirm in time.

2. Why can’t it replace nucleic acid detection?

or false detection According to the latest plan, nucleic acid testing is still the basis for the diagnosis of new coronavirus infection.

Antigen detection is a supplementary method and cannot replace nucleic acid detection.

The reason is that the sensitivity of antigen detection is relatively low. And antigen detection products can usually only be detected when the infected person is in the acute infection stage.

That is, when the viral load in the body is at a high level.

Compared with nucleic acid detection, antigen detection has poor sensitivity due to no amplification process.

In layman’s terms, it shortens the time for results, but increases the risk of “false negatives”.

According to the above plan, if the primary medical and health institutions have nucleic acid detection capabilities, nucleic acid detection should be the first choice;

If they don’t have nucleic acid testing capabilities, they can do antigen testing.

In the current epidemic, there are many asymptomatic infections.

Can we get through testing?

From the existing data, a large part of the infected people of the Omicron variant are asymptomatic, but it does not mean that their viral load is low.

On the contrary, some studies have shown that the viral load in the throat of some asymptomatic infected people is quite high.

Covid 19 Rapid Test Kit

Posted on 2022年2月25日2022年3月22日 by Dr. Lee

The ribonucleic acid of the new coronavirus is RNA, and the detection of the ribonucleic acid of the virus is the detection of RNA.

Moreover, nucleic acid testing is an important means to confirm whether the new coronavirus is infected.

At present, nucleic acid detection of the new coronavirus mainly uses RT-PCR nucleic acid detection kits.

Simply put, the inspectors will use nucleic acid extraction kits to extract nucleic acids from patient specimens and put the extracted nucleic acids into nucleic acid detection reagents for replication.

If the test result is negative, it means that the patient may not be infected with the new coronavirus. If the test is positive, it means that the patient is infected with the virus.

The Cell medical COVID-19 Antigen Self-Test (At Home Kit) provides quick results in the convenience of your home. An easy COVID-19 infection detection solution, this 15-minute test can be done anytime, anywhere. Detect multiple variants.

Cell medical Covid 19 Rapid Test Kit home test

For consecutive (repeated) tests, simply test yourself twice within 3 days, at least 24 hours apart (and no more than 48 hours apart). A single test is available if you have symptoms.

Please read the full instructions included in the box carefully before starting the test.

This self-test kit is suitable for asymptomatic people, and the nose and throat are swabs to determine whether they are infected.
Asymptomatic infection refers to people who carry the virus but have no symptoms.

If you test negative for COVID-19
Most likely you were not infected when you were tested. However, a negative result does not guarantee
You do not have COVID-19.

Covid 19 Rapid Test Kit, including extraction tube holder, sealed packaged test strips, extraction buffer bags, extraction tubes, garbage bags, sealed packaged flocked swabs, and instructions;

How do I use the Covid Rapid Test Kit home self-test kit?

Open the package and take out the test card.
Using the Flocked swab from the kit, insert the entire soft tip of the swab into the nostril.
Rub the inside of the nostril with a cotton swab. Make at least 5 large circles. Don’t just spin the swab.
Using the same swab, repeat steps 1 and 2 in the other nostril. Each nostril must be wiped for about 15 seconds.
Install the stirrer on the extraction tube, drop two drops into the sample hole of the test card, and start the timer.
After performing the test, be sure to wait at least 15 minutes for your results to be available.
Test again in three days (with at least 36 hours between tests).

Rapid Antigen Test Kits for COVID-19 Learn more

How accurate are saliva swab DNA tests?

Posted on 2022年1月4日2022年1月4日 by Dr. Lee

Is the DNA test of the saliva swab accurate?

Many people doubt the accuracy of the saliva swab test.

However, you can rest assured, because the accuracy of oral saliva swab testing is as accurate as other DNA testing methods.

Moreover, this is not the same as a finger puncture or a blood test, it is not painful at all.

In recent years, DNA testing has become more and more popular.

Whether you want to confirm your parental relationship, understand where your genes come from or want to optimize your exercise.

We are currently working on direct-to-consumer DNA testing of saliva swabs.

You have decided to use DNA testing to better understand your body and optimize your training.

However, before you take the first step and buy a set of home DNA testing kits, you should have some concerns.

Although most of the feedback and research has been confirmed to be positive, we are here to learn more about this and help you make an informed decision.

How much saliva is needed for a DNA test?

Saliva Sample Collection Kit: Disposable saliva DNA RNA sampling tube

2ml-4ml.

The saliva collection components are easy to use, and each set has detailed instructions.

You can provide samples for different health conditions, including common medications used during pregnancy, colds or flu (including medications for acid reflux or heartburn).

But if you want to use drugs to reduce the white blood cell count, such as chemotherapy, you’d better wait two weeks or wait until the white blood cell count returns to normal.

After mixing with DNA stabilizing buffer, the temperature range of your saliva sample (-4oF to 122oF) is stable.

Please send the collected samples to the laboratory as soon as possible.

Is the DNA test at home accurate?

Yes, DNA testing at home is very accurate.

You will only encounter errors when the genetic sample is damaged (for example, you have eaten before the sample is collected) or the laboratory quality is poor.

Therefore, it is necessary to choose a well-known DNA testing supplier for testing.

An accurate genetic test report can know in advance whether the body is in danger of disease.

By improving the living environment and behaviour habits, avoiding or delaying the occurrence of the disease, or determining whether there is a specific drug in the case of malignant disease.

Target, so as to more accurately select the treatment method.

The results in each report are derived from at least three peer-reviewed research papers.

It just repeats the genes that have an impact on health, health and nutrition.

This means that you can change the way of real-life based on the genetic variants you carry.

Through strict internal and external procedures, we have passed ISO27001 certification to identify risks, evaluate all control systems, improve our reliability and security, and comply with international data security standards, so as to ensure that our customers and business partners can trust us.

What can you do to ensure that your DNA test results are accurate?

In order to ensure that your DNA test results are accurate, you need to follow the instructions at the back of the box.

Before starting, please read the instructions carefully:

Before wiping dry, make sure you have nothing to eat or drink.

-The best time to take the exam is to brush your teeth in the morning and the first thing before drinking the first cup of tea.
Before taking the test, it is best to open the sealed mouth swab to ensure that it will not be affected.

After removing the cotton swab, open your mouth and use a pointed tip (cotton swab, slightly larger) to gently wipe your cheeks.

Try not to scrub vigorously, because the important part of the sample is saliva.

Be sure not to put paper towels in the plastic container provided.

Take care to break the pole where it is needed.

Fill out the attachments, sign and seal the enclosed envelope, and then send it to the laboratory for inspection.

Bear with patience and watch your test. This process will start with the receipt of samples in the laboratory and will take 10-14 days.

Is the accuracy of mouth swab detection relative to other DNA collection methods?

Because the saliva swab is noninvasive, many people question its accuracy.

However, you can rest assured that the accuracy of oral swab detection is as accurate as other DNA detection methods. And, unlike finger punctures or blood tests, it doesn’t hurt at all.

Whether you are building a cabinet in IKEA, pressing a map or doing DNA testing, you can get accurate results as long as you follow the instructions.

Remember, DNA testing is wrong only if your test results are wrong or you don’t follow the instructions.

Cost is an important factor in performing such tests, so it must be studied.

Often, you don’t just pay for the test suite. You also have to pay a test fee to analyze your results. If the test you selected does not belong to the laboratory, please choose a supplier with a good reputation and excellent laboratory.

Every laboratory we use will conduct regular spot checks to ensure that your samples have been tested correctly and your results are 100%.

One Pass Swab Test Result 2021

Posted on 2021年12月9日2022年3月22日 by Dr. Lee

One Pass Swab Test Result 2021

As we learn more about COVID-19,

Protect yourself and others: COVID-19, do a new crown swap test and get a new crown vaccine.

On this page, you will learn:
What should we pay attention to during holiday gatherings?

Of course, Cell Medical recommends minimizing unnecessary gatherings. For you and your family and friends.

The latest mutation of the new crown epidemic has increased the risk of transmission.

Faced with the epidemic, but the company arranges to travel, what should I do?

Please do a nasopharyngeal swab test before going home.

About nylon flocked nasal swab

What should we pay attention to during holiday party activities?

Cell medical company offers a variety of ways to enjoy the holiday tradition and protect your health.

We encourage colleagues in the United States to take the following steps to make your holiday gatherings safer.

To do a nasopharyngeal swab test, maybe we have to confirm whether we have been to a high-risk area before the party. Whether to carry the new crown virus, a flocking nasopharyngeal swab test is the best choice.

Take a COVID-19 swab test so you can find out before you go. You can go to the test site or use the home test program. Of course, we recommend that you go to a professional testing agency for nasopharyngeal swab testing.

Some locations may be closed on or around holidays. Check it a few hours before departure.

vaccination. The best way to ensure the safety of your family and friends is to get vaccinated if you and your family are eligible.

If you feel unwell, please stay at home. If you have symptoms of COVID-19 or a positive swab test, please stay at home and away from others. And notify the government personnel of the first pass to conduct another virus test, and do not attend the party.

Of course, nowadays, you must wear a mask before going out. This is for the health of you and your family and friends.

You need to wear a mask when taking public transportation, including buses and airplanes.

Of course, party us

Gather in an outdoor or well-ventilated place.

According to experience, the most likely way of transmission of the virus is through saliva or droplets. Therefore, during the epidemic period, try to avoid contact with others and face-to-face conversations.

During the party, we should pay attention to eating clean cooked food and boiling water.

Ask the party host to try not to choose to eat some wild, uncommon, and strange food.

At the same time, the weather is volatile, and your handsome colleagues pay attention to adding or removing clothing.

Finally, Cell Medical recommends minimizing unnecessary gatherings.

The latest mutation of the new crown epidemic has increased the risk of transmission.

Infectivity may increase by 500%! Powerful mutant strains broke out in various countries in the world!

On the 27th local time, several countries and regions, including the United Kingdom, Germany, Italy, and Israel, discovered the new variant “Omicron” (Omicron) of the new crown.

At this stage, countries around the world have tightened their epidemic prevention measures at different levels.

The Israeli government announced that it will gradually prohibit all foreigners from entering the country on the evening of the 28th local time. Resolutely putting an end to the spread of the “new coronavirus mutant strain Omi Keron” has become a new starting point for epidemic prevention worldwide.

Authoritative American experts think: “The infectivity of the new mutant strain may increase by 500%.”

On November 27, WHO announced that the new mutant strain discovered in South Africa was named Omicron.

On the 26th local time, the Federation of American Scientists emphasized that in comparison with the Delta mutation, the total number of “bad thorn gene mutations” in the new mutation was twice that of Delta.

“The B.1.1.529 variant is likely to have a strong charisma of 500%, which is by far the most surprising statistic.”

On the 26th local time, the United States announced that it will gradually restrict the citizens of South Africa and seven other non-US African states to travel to the United States from the 29th.

Previously, the United Kingdom, the European Union, and many other places have called for the suspension of flights originating from African countries.
The new mutant new coronavirus “Omi Keron” first discovered in South Africa has spread rapidly

According to foreign media reports, in Gauteng Province, where the population of South Africa is more concentrated, 90% of the recent increase in virus cases is related to this strain. The Israeli Ministry of Health issued a statement on the 26th stating that the first case of “Omi Keron” virus infection was found. The case came from Malawi, Africa, my country. The Belgian Minister of Environmental Health, Van den Brock, confirmed that the host country has found the infection case of the mutant strain “Omi Keron”. According to reports, this is also the first diagnosed case in Europe.
The first case of Omi Kiron strain infection occurred in Italy…

The spread of new mutant strains is astonishing, which has aroused great vigilance in all countries!!!

Facing the epidemic, but the company arranges to travel, what should I do?

Of course, the best option is to refuse a business trip. But often this is not something we can decide.

Everyone is based on the following suggestions to alleviate the spread of COVID-19 to protect themselves and others.

The more processes you use to mitigate the spread of COVID-19, the safer you will be. When it comes to avoiding the spread of COVID-19, no step is perfect.

1. Reduce your risk of COVID-19

2. Actions and natural environment maps with lower risk and higher risk.

3. Proposals for participants and theme event planners: COVID-19

Vaccination. The COVID-19 vaccine is one of the appropriate ways to avoid being infected or spreading COVID-19.
If you are not vaccinated (including children)

Maintain a minimum distance of 6 inches from people from other homes.
When you cannot maintain a 6-inch distance from others, please wear a mask in the room and outdoors.

If you are vaccinated or not vaccinated, Cell medical strongly recommends that you:

1. Wash your hands frequently, maintain your hygiene, and open windows every day for ventilation

2. Try not to go out, if you go out, try to wear a mask

3. Try not to hold parties and avoid contact if it is not necessary

4. Pay attention to eating habits, eat more fruits and vegetables, exercise, and keep a good sleep

5. Cover your nose and mouth when sneezing, and don’t spit anywhere

If possible, work from home.
Clean and disinfect the surface.

Please do a nasopharyngeal swab test and isolation work before going home. For the health of you and your family.

About nylon flocked nasal swab.

Iclean nylon flocked swab is ideal for bacteriological sample processing, virological cell culture, DFA test, rapid and direct test, enzyme immunoassay test, polymerase chain reaction, and molecular diagnosis based test, as well as forensic identification.

For throat sampling of respiratory viruses such as influenza, swine influenza, avian influenza, hand, foot, and mouth.

About COVID-19 Swab Test

Posted on 2021年12月1日2022年3月22日 by Dr. Lee

About COVID-19 Swab Test

The new crown virus has mutated continuously.

From Delta to Omi Keron, the COVID-19 virus has continued to mutate, and the global epidemic is prevalent at a high level.

Canada announced that all entry personnel from all countries except the United States are required to be tested for the new coronavirus.

At this time, whether you are leaving the country or entering the country.

I even worry or doubt whether I have contracted the coronary disease.

Perhaps understanding the new coronavirus test has become a compulsory course for most people.

What is the new crown swab test, how to collect a nasopharyngeal swab? Is nasal swab sampling painful? If your test result is positive, what do we need to do? Why do most virus tests choose to flock swabs? Is nasopharyngeal swab accurate? Should you be tested for nasopharyngeal swab samples?

We talked with Dr. Li of Cell medical to learn more.

What is the COVID-19 test and what are the test methods?

Nucleic acid detection (RT-PCR Test) method, antibody detection, and antigen detection.

A swab test simple, effective, and fast way to detect COVID-19.

Including nasopharyngeal swab testing and oropharyngeal swab testing.

Medical staff will use flocked swabs to take samples from the nose and throat and put them into the virus sampling tube.

There are two types of swab sample testing: molecular test (PCR) and antigen test.

How to perform a COVID-19 nasal swab test?

The COVID-19 nasal swab test involves inserting a 6-inch flock (a long stick with a very soft brush) into the cavity between your nose and mouth (nasopharynx).

The medical staff inserts the flocking swab into each nostril for about 15 seconds and rotates it several times to collect enough samples for testing.

The samples are then sent to the laboratory for testing, and our test results are usually known within or within the next day

Since the nasopharynx is in a sensitive position of the body, it will produce a lot of very strange sensations.

On the one hand, the swab is inserted deeply into your nose and it irritates the lacrimal glands.

At this point, you don’t know if you are moved to tears or you are crying in pain.

The nasal swab test is not very painful, but it is very uncomfortable. Some people may have nausea during the nasopharyngeal swab test. Nasal swab painful.

Because the swab will also touch the back of your throat, this reaction is normal.

Whether it is tearing or nausea, nasal swab testing is a common phenomenon.

Don’t worry, everything is normal.

Are there other types of COVID-19 swab test methods available?

Yes, an oropharyngeal swab is one of the options.

Of course, if you want to experience another feeling, an anal swab test is also a good choice.

But they are not as sensitive as the COVID-19 nasal swab test.

Israel’s development of the new coronavirus “saliva detection method” saliva detection still needs scientists to confirm on a larger scale. There is no conclusion yet, but it is promising.

In addition to nucleic acid testing for the detection of viral genetic material, there is also antigen testing.

Currently, nasal swab testing for COVID-19, including nucleic acid testing, is still the best choice.

How about the covid test kit at home? Are their results reliable?

The home covid test kit sounds very attractive.

Home covid test usually refers to individuals collecting samples of themselves or their family members through sampling swabs.

We put the collected samples in test tubes with a virus transport medium, and then transport them to the testing facility.

Although you can use the Home covid test kit to test COVID-19 safely and comfortably in your own home.

However, Dr. Li suggested that it should be carried out at a professional testing institution.

Because the quality of the samples we collect and the integrity of the samples during transportation will affect the sampling results.

How accurate is the nasal swab test for COVID-19?

How to obtain a precise nasopharyngeal swab specimen?

Polymerase chain reaction (PCR) uses a piece of DNA as a template.

Then, with the participation of DNA polymerase and nucleotide substrate, the DNA is amplified to a sufficient amount for structural and functional analysis.

Pcr nasal swab test can be said to be very sensitive.

Scientists use PCR technology to amplify a small amount of RNA in the sample into deoxyribonucleic acid (DNA) and replicate it until COVID-19 (if present) is detected.

The following may affect the accuracy of PCR nasal swab sampling.

1. Smoking, drinking or chewing gum 30 minutes before use may also interfere with the test results.

2. Touching the swab with the hand or other objects and using the tip of the cotton swab will affect the accuracy of the detection.

Of course, the professionalism of the most important sampling personnel, we have to choose a professional testing agency for testing. And professional VTM Kits.

What should I do if the new coronary pneumonia nasal swab test is positive?

Very bad news!

If the COVID-19 nucleic acid test is positive, a single room isolation treatment should be carried out immediately.

Consultation by in-hospital experts or attending physicians will conduct multiple tests.

Under the premise of ensuring safety, the patient is safely transferred to a designated hospital for diagnosis and treatment.

Don’t worry. You need to actively cooperate with treatment

Otherwise, life is likely to be in danger, and large-scale infections will also occur.

In addition, proper physical exercise should be carried out in life to enhance the individual’s immunity. Colds and fatigue should be avoided.

Don’t do strenuous exercise, so as not to aggravate the disease.

A friend around me was infected with COVID-19. But my nasopharyngeal swab was negative. Is there any way to confirm that I have had it or am I immune to it now?

Certainly.

Antibody test, also called serological test, can detect the antiviral protein IgM and IgG antibodies produced by your immune system in the blood.

What are the types of samples for serum antibody testing?

It is generally blood, including serum, plasma, and whole blood.

PCR swab test, antibody test, and antigen test difference (Please click here)

Quick covid test |How does covid testing work?

Posted on 2021年11月10日2021年11月10日 by Dr. Lee

A new covid test at home has been authorized by the U.S. Food and Drug Administration (FDA) for emergency use (EUA).

Here’s what you need to know about testing at home.

How can I get quick covid test?

Cell medical’s covid test at home now has a prescription, which means Americans can get one from their health care provider.

If doctors suspect that their patient is infected with covid – 19 within the first six days of symptom onset, they can prescribe a rapid test.

Quick covid test Rapid Antigen Test Kit Nasal Saliva Test at home

How much does it cost?

Please contact us for more details.

E-mail：flockedswabs@gmail.com

How does testing work?

Rapid Antigen Test is a lateral flow test, a portable covid test that usually returns results faster than the widely used laboratory based PCR test.

It works by detecting nasal swab samples and provides positive or negative results within 10 minutes. The results appear on test strips exposed to nasal swab samples.

The FDA said flocked swab can be collected from people aged 8 and over, but if the tested children are less than 14 years old, it should be collected by adults.

How accurate is the test?

Cell medical claimed that the time when the positive results of the test matched the PCR test was 84.8%, and the negative results matched the PCR test were 99.1%.

FDA said that the negative test results of covid test do not necessarily exclude the possibility of covid – 19 infection.

“and should not be used as the only basis for treatment or patient management decisions, including infection control decisions.

“People who are negative and continue to experience COVID 19, have a fever, cough and / or shortness of breath, may still have SARS – CoV – 2 infection. Follow up care should be sought from doctors or medical staff. ”

Not all side flow tests require the use of prescriptions. On December 15, the FDA issued the EUA for the first outside counter flow covid test at home.

The covid – 19 family test also uses nasal swab samples to detect covid infection and works with people aged 2 years and older.

The FDA said that in the population with covid symptoms, the ellume test correctly identified 96% of positive samples and 100% of negative samples. In the population without symptoms, it collected 91% of positive samples and 96% of negative samples.

Similarly, the FDA said that the negative results of the test do not necessarily exclude the possibility of covid infection.

Broader prospects

According to CDC data, as of Monday, the United States had reported 47.5million cases of covid and 778,316 deaths.

The data also showed that 432 million people were vaccinated on Monday.

A stock photo shows a schoolgirl receiving a nasal swab sample.

The covid test uses self collected swab samples.

But adults should take samples from children under the age of 14 and over the age of 8.

Nasal swab quick covid test.

Saliva Sample Collection Kit :Disposable saliva DNA RNA sampling tube

Posted on 2021年9月18日2022年3月22日 by Dr. Lee

What is saliva collection kit?

In recent years, with the development of medicine, the examination technology has become more and more high-end. And the examination items have become more and more accurate.

Saliva is a complex mixture, which not only contains various proteins. It also contains DNA, RNA, fatty acids and various microorganisms. Therefore, it is possible to diagnose diseases by detecting saliva. Gene detection and analysis.

Saliva collector plays an important role in the process of collecting, transporting and storing saliva samples.

It is noninvasive and easy to self-management, and reduces the risk of medical staff exposure.

Saliva Collection Kit suitable for SARS-CoV-2 sample collection.

Nucleic acid detection is the most widely used new crown detection method.

Including PCR nasopharynx swab, oropharyngeal swab and saliva sample test.

High precision. As long as the collection, breeding and separation of nucleic acids are successful, there is basically no false positive or false negative.

But the sampling staff are easy to be exposed and the risk is high; With one more step of extracting nucleic acid, unskilled technicians are likely to fail to extract, resulting in false negative, or pollute with other people's samples, resulting in false positive.

Pcr test nasal swab and an antigen test difference for covid 19

Posted on 2021年9月18日2022年3月22日 by Dr. Lee

Pcr test nasal swab and an antigen test difference for covid 19

What is COVID-19?COVID-19 is an epidemic disease caused by SARS-CoV-2. An acute respiratory infectious disease broke out at the end of 2019. So far, WHO has been making the latest tracking report on the new pneumonia on the Internet every day.

What are the current methods of COVID-19 test?

Virus detection includes two types: nucleic acid amplification test (NAAT) (PCR test) and antigen test.

Antibody tests (also known as serological tests) can prove whether you have been infected in the past.

What is the COVID-19 PCR test?

PCR (polymerase chain reaction): similar to the natural replication process of DNA, its specificity depends on oligonucleotide primers complementary to both ends of the target sequence.

Basic principle: the basic principle of PCR technology is similar to the natural replication process of DNA. Its specificity mainly depends on the oligonucleotide primers complementary to both ends of the target sequence. It consists of three basic reaction steps: denaturation, renaturation and extension.

PCR test sample collection method include:

If the sample contains a virus, the researchers will extract its RNA.

Why use the PCR test ?

PCR nucleic acid examination is a direct detection of COVID-19 RNA in human body by sampling from the nasal cavity. The structure of virus is composed of DNA or RNA combined with external lipid protective capsule. Therefore, direct detection of virus DNA itself is the most accurate, fastest and effective new detection method. PCR nucleic acid test can detect infection immediately after the human body obtains the virus, and the accuracy is much higher than antibody test.

ABOUT PCR TEST_Pcr test nasal or Throat swab sampling

How does the PCR test nasal swab work?

Nasopharynx swab is to wipe the secretion of the patient’s nasal cavity or pharynx. And then make the secretion into smear for examination and bacterial culture to clarify what bacterial infection is in the patient’s nasal cavity and pharynx.

Nasal swab sampling procedure

1. Keep the patient’s head still and remove the secretions on the middle surface of the anterior nostril;

2. Gently and slowly insert the swab through the nasal cavity to the nasopharynx;

3. After encountering resistance, it reaches the posterior nasopharynx and stays for several seconds to absorb secretions;

4. Gently rotate and take out the swab and place it in the transport medium;

5. For the swab used for virological test, immerse the swab head into the virus delivery medium, discard the tail, and tighten the tube cover;

If it is necessary to collect from both nostrils, the sampler should use the same swab.

How does the antigen test work?

Rapid antigen detection can play an important role in guiding patient management, public health prevention and control decision-making and covid-19 monitoring.

It is especially valuable for grass-roots areas that may hinder clinical diagnosis and control due to lack of nucleic acid detection capacity or long detection time.

According to WHO, high specificity based on antigen detection indicates that the positive results indicate new crown virus infection.

For patients within 9 days of onset, sampling personnel can use antigen detection as a diagnostic test.

Especially for the staff of medical institutions, inpatients and visitors in the epidemic area.

When nucleic acid detection cannot be effectively implemented, antigen detection can be used as an important screening method.

Rapid antigen test sampling procedure.

Rapid antigen test sampling process

Generally speaking, nucleic acid detection: it has high requirements for laboratory environment, detection personnel and instruments. The detection has high sensitivity and good specificity.Generally, we can get the results in 2-3 hours.

Antigen detection: it has low requirements for the laboratory. For early screening and early diagnosis. It is suitable for large-scale screening in grass-roots hospitals. we can obtain the results within 15 minutes at the fastest.

At present, PCR test nasal swab is widely used, and the sensitivity and specificity of antibody / antigen detection reagents are still limited.

Each has its own emphasis and cannot replace each other. We should combine multiple virus detection methods.

It can effectively shorten the detection window period and improve the positive detection rate.

Sample collection swab :How much do you know about nucleic acid testing

Posted on 2021年9月10日2022年3月22日 by Dr. Lee

Sample collection swab:How much do you know about nucleic acid testing

The spread of the covid-19 is continuing worldwide. Although the global scientific and medical circles are making every effort to fight the epidemic, it is difficult to predict how the epidemic will develop in the future, and its impact on social development has appeared in many aspects.

Currently, COVID-19 cases are over 220 million.

In order to fully control covid-19, the general screening of local areas shall be carried out if necessary.

After identifying the detection object, how to detect it?

1、 What specimen to choose?

According to the recommendations of the American infectious diseases association, the following specimens were used:

Nasopharyngeal swab
Middle turbinate swab
Anterior nostril swab
saliva
Anterior nostril + oropharyngeal swab
Alveolar lavage fluid
Anal swab

The sensitivity of simple oropharyngeal swab may not be enough, so it is relatively easy to miss diagnosis.

The sensitivity of alveolar lavage fluid is the highest, but it is obviously not suitable for universal screening.

Nasopharynx swabs and other operations should also be standardized.

Improper operation may make the quality of collected samples not high, thus increasing the risk of missed diagnosis.

2、 Select the time of detection

It is very important for COVID-19 to measure RNA and choose the right time. One analysis included 7 studies, including 2 unpublished reports, to evaluate the detection efficiency of RT-PCR at different time points after exposure to virus :

On the day of exposure to the virus, the possibility of detecting viral RNA is almost zero;

On the fifth day after exposure, that is, the first day after infection, the detection probability was 62%

About the 8th day after exposure, i.e. the 4th day after infection, the probability of detection was 80%

On the 21st day after exposure, i.e. the 17th day after infection, the detection probability was 34%

In conclusion, exposure to COVID-19 may require multiple tests to avoid missed diagnosis. However, it is not recommended to repeat the test within 24 hours of the previous test; The interval between two tests shall be at least 24 hours.

After 28 days of exposure to the virus, if the infection has not been diagnosed, it is not necessary to continue the detection; At this time, it is almost certain that it is not infected.

Nucleic acid detection throat swab sampling process

The COVID-19 nucleic acid was novel coronavirus, which was collected from sputum or lower respiratory tract by real-time fluorescent RT-PCR. If positive, the new coronavirus could be diagnosed. This is the basis for the diagnosis of new type of pneumonia. In addition to detecting the nucleic acid of the virus, it can also detect whether the virus in the specimen is highly homologous with New Coronavirus. If so, it can be diagnosed as New Coronavirus pneumonia. The virus is highly infectious and has the characteristics of human to human transmission, but the virus is sensitive to temperature and sunlight and ultraviolet rays.

Sample collection, nasopharyngeal swab sampling

Sample collection, Oropharyngeal swab sampling

The flocked swab is the best raw material for sampling swabs.

reference

1，Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19, updated December 23, 2020. https://www.idsociety.org/practice-guideline/covid-19-guideline-diagnostics/ (Accessed on January 14, 2021).

2，Kucirka LM, Lauer SA, Laeyendecker O, et al. Variation in False-Negative Rate of Reverse Transcriptase Polymerase Chain Reaction-Based SARS-CoV-2 Tests by Time Since Exposure. Ann Intern Med 2020; 173:262.

Saliva Collection Device