Viral Transport Media Kit

Viral Transport Media Kit

CellMedical Viral Transport Medium

CellMedical's viral transport medium is designed to transport viruses, chlamydiae, mycoplasmas, and ureaplasmas at room temperature.

Adapted to transportation for coronavirus, the virus of flu, bird flu, hand-foot and mouth disease, measles, etc. It is also adapted for the collection and transport of Viruses, such as Chlamydia, Mycoplasma, and Ureaplasma specimens. Generally collect specimens from the Oral cavity, throat, nasopharynx, anus, etc.

Virus Collection and Sampling Transport Tube

1. It is used for the collection and transportation of clinical covid-19, influenza, avian influenza (such as h7n9), hand, foot and mouth, measles, norovirus, rotavirus and mycoplasma, Ureaplasma and chlamydia.

2. The virus and related samples shall be stored and transported within 48 hours under refrigeration (2-8 ℃).

3. Long time storage of virus and related samples in - 80 ℃ environment or liquid nitrogen environment.
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Nylon flocked swab

Innovative jet embedded nylon modern technology can improve the effectiveness of the example collection from the client to the largest degree. The nylon has stuck vertically and uniformly to the surface of the swab pointer, which can boost the effectiveness of accumulating as well as releasing cells as well as liquid samples. Improve analytical level of sensitivity, No sampling recurring, and can speed up the specimen therapy. PS sticker label is very easy to break short. Adjusted to cervix wombs, nasopharynx, oral cavity, Forensic Purchase System as well as DNA accumulating, etc. Private stuffed.

Features

1. Flocked swabs provide the best sampling effect. Groups of swabs are the best choice for rapid diagnostic testing because they can better collect cells or organisms at the collection point and quickly release intact cells.

2. Enhance the sensitivity of diagnosis. The patented flocking technology turns each strand of fibre into a velvet brush, resulting in hundreds of thousands of contact points, which can better collect and release samples. The increase in the number of target cells (compared with non-flocking swabs) helps to improve the sensitivity of rapid diagnostic tests.

3. The flocking swab with rapid elution of CellMedical is closely combined with the handle and does not contain the internal fabric or other inner cores that absorb the samples, which can collect and retain more samples. This can not only provide a better sample size but also make the sample released into the liquid medium more quickly and completely.

4. Proprietary long flocking fibre flocking swab the proprietary long flocking fibre forms a network structure, which can collect and retain more specimens than traditional cotton, polyester or man-made fibre swabs. The inner core of an ordinary cotton swab will easily lock the sample, making it difficult to elute and pour it into the medium.

5. Convenient handling and transportation. Most oral, oropharyngeal and nasopharyngeal flocking swabs have prefabricated breaking points, so you can easily break the handle before putting the swab into the vial. Sterile flocking cotton swabs will also be equipped with dry transport tubes and media filling transport tubes and other transport materials. After sampling, the storage and transportation can be completed conveniently.

In a word, a flocked swab can better meet the sample collection needs of laboratories, hospitals and other institutions. It is the preferred tool for sample collection and elution.

 

flocked swab
Oral swab
Nasopharyngeal swab

Viral Transport Medium

The virus transport media tube and cap are made of medical-grade Polypropylene, with No deformation after HTHP (121 ° C, 15min ), and no embrittlement under low-temperature levels (-196 ° C). it can bear fixed extrusion and dynamic effects.

The taper lower layout makes it bear centrifugation and also shaking. It's watertight. Offered with non-pyrogenic as well as DNase/RNase-free.

Model Specification
VTM-B-CM040320S 2With Nasal Swab& Throat Swab;  3ml inactivated medium;10ml tube
VTM-B-CM040311S With Nasal Swab; 3ml inactivated medium;10ml tube
VTM-B-CM040312S With Throat Swab; 3ml inactivated medium;10ml tube
VTM-A-CM040320S With Nasal Swab & Throat Swab  ;        3ml Non inactivated medium ;10ml tube
VTM-A-CM040311S With Nasal flocked Swab ; 3ml Non- inactivated medium ;10ml    tube
VTM-A-CM040311S With Throat Swab ; 3ml Non- inactivated  medium ;10ml tube
Flocked Swab With Vtm Kits Leading China Manufacturer

Flocked Swab With Vtm Kits Leading China Manufacturer

Cell medical (Dongguan) Co., Ltd., established in 2009, a swabs design/swabs manufacturer, has many years of experience in medical application molding and flocking treatment heads and swabs.

We produce flocked swabs, VTM kits, and virus transport medium, with multiple automatic production lines(Including automatic VTM tube production line, OEM VTM Tube, Flocked Swab Production Line, etc).

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Flocked Swab Influenza

Flocked Swab Influenza | Comprehensive Flu Swab Test Guide

Flu Flocked Swab Influenza

Influenza refers to the common cold, which is an acute respiratory infectious disease caused by the influenza virus.

It is highly contagious and mainly spreads through droplets, such as coughing and sneezing. Influenza generally occurs in winter and spring.

The current influenza detection method is the rapid influenza antigen detection method, which detects “flux A” and “flu B” antigens.

Laboratory staff collect samples through throat swabs.

In fact, in inspection work, it is important to know the quality of the specimen in order to obtain accurate and reliable results.

Throat swab specimens: Professionals can avoid many false-negative influenza tests caused by improper specimen sampling.

The precautions for flu throat swabs are basically the same as those for nucleic acid detection throat swabs. Because the same part is sampled.

There are two types of flu throat swabs: nasopharyngeal swabs and oropharyngeal swabs.

What precautions should I take when taking a throat swab test for flu?

1. Oropharyngeal swab The collection method of the oropharyngeal swab is to let the subject open his mouth, then use a long pharyngeal swab to wipe the patient’s pharynx, bilateral frontal arches and tonsils, and take out the local secretions. Into the catheter of the throat swab and sent to the laboratory for testing.

2. Nasopharyngeal swabs The collection method of nasopharyngeal swabs is to use sterilized throat swabs to penetrate deep into the nasal cavity of the subject and reach the nasopharynx, and extract secretions and nasopharynx by rotating or wiping.

Epithelial cells put a section with secretions and epithelial cells into a sterile container and then carry out pathogenic detection.

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Flu swab material

Swab options for flu testing include flocked swabs, cotton-tipped swabs, rayon tipped swabs, and foam-tipped swabs.

Cotton tip swab:

The original swab tips were all cotton, mainly based on their cleaning power and water absorption. Cotton swabs are very inexpensive and readily available, and are widely used in medical wound management after sterilization with ethylene oxide or autoclaving, as well as in forensic crime scene forensics. In the absence of alternatives, cotton swabs can be used in almost a variety of scenarios.

However, cotton-tipped swabs also have some problems. Due to the low release rate of cotton, natural material for samples, and some of the natural fatty acids in it can damage microorganisms, they are less and less used for sample collection.

Rayon head swab:

Rayon—a synthetic fiber made from wood pulp. Although classified as synthetic fiber, it is essentially a natural material. Compared to cotton, rayon is produced during the process of removing substances that may damage the sample or react with the sample during transportation and handling , so it is generally used for sampling for diagnostic testing.

Polyester Fiber Tip Swabs:

The head material of the polyester fiber swab is made of polyester long fiber winding, which was first introduced into the field of medical testing by DuPont. Polyester fibres are proven for microbial collection, rapid diagnostics, and PCR testing.

Polyester swabs have a high release rate but are more expensive than cotton and rayon swabs.

Foam tip swab:

China Medical Nasal Foam Swab Factory And Manufacturers

China Medical Nasal Foam Swab Factory And Manufacturers

Swabs made from medical-grade polyurethane are an excellent material for diagnostics, especially cell sampling. The swab tip of this swab is usually manufactured as a sheet with a surface hole count of 100ppi (holes per inch).

This material has good absorption of hydrophilic substances and poor absorption of hydrophobic substances. Used in some scenarios that require resistance to chemical corrosion. Also used for DNA and microbial sampling.

Flocked Swabs:

Flocking technology was first developed for cosmetic and industrial production. (Learn more)

After the flocking process was introduced into swab production. It replaced the traditional swab head, and the swab head was brought to a new level.

vtm swab

Due to the flocking process and the multi-branched polyester fibre material used, the flocked swabs have a very high absorption and release rate and are proven to be equally efficient for molecular sampling and absorption. Designated by some institutions for nucleic acid sampling as well as some research areas for genomic analysis.

The evolution of swabs is not limited to changes in materials. New demands in the fields of nursing, testing, and scientific research make swabs continue to evolve in multiple dimensions. The swab also not only acts as an applicator, but also acts as some transport medium.

Precautions include the following:

① Do not drink water before the throat swab test, at least 30 minutes in advance, because drinking water before the test will dilute the virus attached to the pharynx, especially drinking hot water will inhibit the activity of the virus.

In order to improve the accuracy of throat swab nucleic acid detection, do not drink water 15 to 30 minutes before the test to ensure that the throat swab has high accuracy.

②. For patients with good throat exposure, it is not recommended to take too long “ah~” sounds to reduce the risk of occupational exposure to the sampler.

③ To prevent vomiting, do not eat within two hours before the throat swab test.

④. Do not smoke, drink, or chew gum within half an hour before the throat swab test.

During the throat flocked swab sampling, the patient may have clinical symptoms such as nausea or nasopharyngeal discomfort, but the symptoms can subside quickly, so the patient should not be nervous and cooperate actively during the examination. At the same time, the subjects should not smoke, drink, or chew gum within half an hour before the sample collection.

If it is because of the throat swab the child, the parents must soothe the child’s emotions, communicate with the child patiently, and try not to move the child’s head as much as possible.

Viral Transport Medium With Swab

Viral Transport Medium With Swab

Viral transport medium with swab

The COVID-19 outbreak is expected to have a significant impact on the tedious market for swabs and virus transport media owing to the increasing patient demand for infection diagnosis.

Flocked Swab and viral transport media are expected to grow due to intensive testing of COVID-19 in research institutions and laboratories.

Rising research and development activities to produce COVID-19 vaccines are expected to drive market growth during the pandemic.

The rising number of COVID-19 cases in the global population is expected to drive market growth.

The need to develop vaccines and early diagnostics to treat infections is expected to boost the market growth.

Manufacturing of Viral Transport Medium

Virus sampling tubes are medical device products. The virus sampling tube consists of a sampling flocking swab, virus transport medium and outer packaging. Since there is no unified national standard or industry standard, the products of various manufacturers vary greatly.

CellMedical manufactures viral transport media (VTM) following WHO and CDC recommendations, with or without swabs.

Flocked swab+tube with Viral transport medium

Flocked swab+tube with Viral transport medium

1. Sampling swab:

Virus sample collection flocked swab

Virus sample collection flocked swab

The specimen collection swab directly contacts the sampling site, and the material of the sampling head is closely related to the subsequent detection.

  Synthetic fibres such as PE synthetic fibers, polyester fibres, polypropylene fibers, and rayon fibres should be used for the manufacture of sampling swab tips.

  (1) Natural fibers such as cotton are not recommended

  Because the fiber of cotton has strong adsorption of protein, it is not easy to be eluted into the subsequent preservation solution;

  (2) Nylon fibers are also not recommended

  Because nylon fibers (similar to toothbrush heads) have poor water absorption, the sampling volume is insufficient and the detection rate is affected.

 (3) Do not use calcium alginate sponges or wooden stick swabs (including bamboo sticks) for the head of the sampling swab.

  Because the broken wooden sticks or bamboo sticks containing calcium alginate and wooden components will also adsorb proteins after being soaked in the preservation solution, and even have an inhibitory effect on the subsequent PCR reaction.

Flocked swabs manufacturers

Flocked swabs manufacturers

Features of CellMedical Flocked Swabs:

1. Has extraordinary adsorption energy.

2. It has a release rate of more than 95% for the collected specimens, thus ensuring a high degree of reliability of the results;

3. There is a unique breakable design on the plastic rod, which is convenient for specimen transportation;

4. Sterilized by ethylene oxide or irradiation, individually packaged;

Nasopharyngeal and oropharyngeal swabs. learn more

 

2. Virus preservation solution (virus transport medium): There are mainly two kinds of virus preservation solutions widely used in the market, one is a virus maintenance solution improved based on the transport medium, and the other is an improved nucleic acid extraction lysate. Preservation solution.

3. Virus sampling tube: The material of the storage tube should be selected carefully. Some data suggest that polypropylene (Polypropylene) is related to the adsorption of nucleic acids, especially at high tension ion concentration, polyethylene plastic (Polyethylene) than polypropylene (Polypropylene) Easier to grab DNA/RNA. In addition, when using breakable swabs, the storage tube should try to choose a container with a height of more than 8 cm to prevent the contents from splashing and contaminating when the swab is broken.

What is Virus Sampling Tube

Virus Sampling Tube

4. Water for production of preservation solution: Ultrapure water used for the production of preservation solution should be filtered by an ultrafiltration membrane with a molecular weight of 13,000 to ensure the removal of biologically derived polymer impurities, such as RNase, DNase and endotoxin, and ordinary purification is not recommended. water or distilled water.

About the use of virus sampling tubes

Sampling using virus sampling tubes is mainly divided into oropharyngeal sampling and nasopharyngeal sampling:

1. Oropharyngeal swab sampling:

first press the tongue with a tongue depressor, then insert the head of the sampling swab into the throat to wipe the bilateral pharyngeal tonsils and posterior pharyngeal wall, and wipe the posterior pharyngeal wall with mild force, avoiding touching the tongue department.

2. Nasopharyngeal swab sampling:

measure the distance from the tip of the nose to the earlobe with a swab and mark it with your fingers, insert the sampling swab into the nasal cavity in the direction perpendicular to the nose (face), and the swab should be inserted at least half the length from the earlobe to the tip of the nose. Leave the swab in the nose for 15-30 seconds, swirl gently 3-5 times, and withdraw the swab.

It is not difficult to see from the method of use, whether it is an oropharyngeal swab or a nasopharyngeal swab, sampling is a technical task, which is difficult and easy to contaminate. The quality of the collected samples is directly related to the subsequent testing. If the viral load of the collected samples Low, easy to cause false negatives, difficult to diagnose.

Most of the samples recommended by the kits currently on the market are oropharyngeal swabs or nasopharyngeal swabs and bronchoalveolar lavage fluid. This can greatly reduce the difficulty of the samplers’ work. After all, it is not difficult to collect venous blood samples, and like the detection of hepatitis C RNA, about 5 ml of EDTA anticoagulated blood samples are separated into plasma, and the extracted and purified RNA can fully meet the needs of PCR detection.

Preservation solution features:

Our independent research and development and production, unique cell preservation technology, can be stored at room temperature for more than 3 years after sampling! No need to refrigerate, store and transport at room temperature.

Viral Transport Medium With Swab Factory

Viral Transport Medium With Swab Factory

By Type
Swab Type
Nasopharyngeal swab
Throat swab
Transmission medium
By Application
Coronavirus disease
influenza
herpes simplex virus
other
By end-user
Hospitals and Clinics
diagnostic laboratory
other
geography
North America
The U.S.
Canada
Mexico
Europe
Germany
The U.K.
France
Italy
Spain
Rest of Europe
Asia Pacific
China
Japan
India
Australia
South Korea
Rest of Asia Pacific
The Middle East and Africa
GCC
South Africa
Rest of the Middle East and Africa
South America
Brazil
Argentina
Rest of South America
Swab Specimen Collection

Swab Specimen Collection

A throat swab refers to the use of a sterile medical long flocked swab to dip a small number of secretions from the pharynx of the subject.

And then carry out the detection of respiratory viruses, bacteria and other pathogenic microorganisms.

The collection site of the throat swab is the pharynx and tonsils of the subject, and precautions should be taken when collecting.

Swab Specimen Collection details are as follows:

Swab Specimen Collection

Swab Specimen Collection

1. Drinking water before the oropharyngeal test strip will dilute the virus attached to the pharynx, especially drinking hot water will inhibit the activity of the virus.

In order to improve the accuracy of the nucleic acid detection of throat swabs, required 15-30 minutes before the test. Do not drink water to ensure the high accuracy of throat swab nucleic acid detection;

2. We do not recommend that patients with well-exposed larynx keep hair in order to reduce the occupational exposure risk of the sampler;

3. To prevent vomiting, avoid eating two hours before collecting throat swab specimens;

4. Do not smoke, drink, or chew gum half an hour before sample collection.

In addition, the basic steps of throat swab collection are:

1. Ask the patient to sit down, tilt their head back, open their mouth wide, and take out the surface secretions in the nasal cavity;

2. The sampler fixes the tongue with a tongue depressor, and uses a cotton swab to cross the base of the tongue to the posterior pharyngeal wall and the lateral wall of the tonsillar recess, etc.;

3. Wipe 3-5 times repeatedly to collect mucosal cells;

4. Gently remove the test strip, avoid touching the tongue, uvula, oral mucosa and saliva;

5. Insert the test strip back into the sampling device or a suitable transfer device.

There are various Specimen Collection swabs available on the market.

Which one is the best one to choose?

CellMedical recommends “synthetic flocked swabs“.

Compared with traditional wound swabs (although they are also made of synthetic fibres), the amount of samples collected and released by this swab is 3 times higher, and it does not damage the cell samples, which can ensure the survival rate of the cell samples and has no fatty acid residues. Contains substances that inactivate certain viruses and inhibit PCR detection.

Nasal Gene Sampling Flocked Swab Oral Gene Sampling Flocked Swab

Although the positive rate of the new coronavirus RNA test is directly related to the quality of the reagent itself, the quality control of the whole process is more critical, which includes sample collection, transportation, storage, testing and all consumables used for testing. As long as one step is not well controlled, it is difficult to achieve the quality (detection rate) of the reagent itself.

What Is Virus Transport Medium

What Is Virus Transport Medium

The virus transport medium is novel and unfamiliar to many small partners, but it is of great significance for the detection of various viruses.

The new crown virus has tortured human beings enough.

In the face of a large number of COVID-19 patients, some places are still rising.

Therefore, as soon as there are new additions, many places will focus on the new crown nucleic acid detection.

The virus preservation solution plays a very important role.

Virus Transport Medium with Specimen collection swab

Virus Transport Medium with Specimen collection swab

At present, the nucleic acid detection of the new coronavirus is mainly the detection of viral nucleic acid.

Virus transmission medium is a cell preservation liquid, which protects the virus to be detected by immersing the flocked swab head with the virus sample into the transport tube.

It is mainly suitable for the new coronavirus, Collection, preservation and transportation of common virus samples such as the influenza virus.

To collect throat swabs, nasal swab or tissue samples from specific parts.

The stored samples: for subsequent nucleic acid detection or clinical experiments such as virus culture.

Since the virus is a parasitic organism, it cannot survive outside the body after sampling.

If it cannot be detected in time, it needs to be placed in a virus preservation solution for preservation. (Virus Transport Medium)

In order to protect the safety of the virus detection environment and the safety of the detection personnel, inactivated virus preservation solution is actually a better choice!

FLOCKED SWAB

FLOCKED SWAB

For different detection purposes, we need to use different virus preservation solutions for preservation.

The two widely used preservation solutions have their own characteristics.

In order to meet different detection requirements and different experimental conditions for virus detection, it is necessary to use different preservation solutions.

The inactivated virus preservation solution can inactivate the virus.

How to detect it after inactivation?

The purpose of our use of inactivated preservation solution is to lyse nucleic acids, release nucleic acids and then carry out nucleic acid detection by subsequent real-time fluorescent RT-PCR.

Doctors use inactivated virus transport media to determine whether the sample contains virus characteristic nucleic acid, that is, whether we carry the virus.

Inactivated virus transport medium:

A virus lysis type preservation solution improved by nucleic acid extraction lysis solution.

Effectively prevent the secondary infection of the operator, but it also contains inhibitors, which can protect the viral nucleic acid from being degraded.

This enables subsequent detection by NT-PCR.

Moreover, stored at room temperature for a relatively long time, which saves the cost of virus sample storage and transportation.

Non-inactivated virus transport medium:

A virus maintenance liquid type preservation solution improved on the basis of the transport medium.

It maintains the activity of the virus in vitro and the integrity of antigens and nucleic acids.

The protective viral protein shell makes it difficult to decompose and maintains the originality of the virus sample to a great extent.

For nucleic acid extraction and detection, the experimenters also use the transport medium for virus culture and isolation and maintain the activity of virus samples.

In addition to nucleic acid extraction and detection, the inspector also uses this preservation solution for virus culture, isolation and antigen detection.

Covid-Nucleic-Acid-Test

Covid Nucleic Acid Test Nasopharyngeal Swab Test

This article
To talk to you in detail
Covid nucleic acid test!

But in the face of the “nucleic acid swab test”
This unfamiliar and familiar word
Do you have many questions?

Image source network

Do you want to do a nucleic acid test when you go back?

Will it be difficult to make an appointment for nucleic acid testing?

How long does it take to get the results of a nucleic acid test at the hospital?

Should I Swab My Throat or Nose for Rapid COVID-19 Tests?

To answer your questions.
Today.
I’m going to tell you.
Those things about nucleic acid testing.

01. What is nucleic acid detection?

At present, nucleic acid detection is the main method for laboratory diagnosis to determine whether a patient is infected with the new coronavirus. It can achieve early detection, early diagnosis, and early treatment. Real-time fluorescent PCR can be used to detect throat swabs, sputum or blood samples. to covid nucleic acid, or detected by viral next-generation gene sequencing.

simply put

Nucleic acid testing is done by

After collecting human secretions

Tested by the instrument

to see if we have the new coronavirus in our body

If so, the test result is positive

On the contrary, if it doesn’t, it’s negative.

02. How to test the COVID swab?

“Sir, oropharyngeal swab, nasopharyngeal swab, and anal swab, which one to choose?”

How do you do a nasopharyngeal swab?

Nasopharyngeal swabs must be performed with the patient sitting upright with the head in an upright position, as this allows for easy visualization and access to the nasal floor perpendicular to the central axis of the patient’s face.

Flocked Tip Swab Nylon Sterile Nasal Swab Stick

Flocked Tip Swab Nylon Sterile Nasal Swab Stick

Insert the swab into the patient’s nose and align it parallel to the nose and the base of the septum. As long as there is no obstruction in the nasal cavity, the swab continues to move in this direction until it reaches the nasopharynx, at which point the tester feels resistance.

Once the swab reaches the nasopharynx, a gentle rotation and two complete 360-degree rotations are recommended to allow secretions from this area to be absorbed.

Once the swab is removed from the patient’s nose, it is immediately inserted into a viral sample containing a viral transport medium. The handle of the swab extending through the opening of the vial was broken off to allow the tube to be closed.

So
Now that there are oropharyngeal swabs and nasopharyngeal swabs
Why add anal swabs?
To answer your questions
Let’s take a look at their respective advantages and disadvantages

The specific operation of the anal swab is as follows:

Soak a flocked swab in saline, insert it 2-3 cm into the anus, wipe from the folds around the anus, or rotate it gently inside the anus, and insert it into a test tube containing saline.

anal swabs

For fecal swab cultures, all of the above requires the use of sterile equipment and placing the swab in a sterile tube.

So
Now that there are oropharyngeal swabs and nasopharyngeal swabs
Why add anal swabs?
To answer your questions.
Let’s take a look at their respective advantages and disadvantages.

Oropharyngeal swab: relatively simple to operate, less irritating, suitable for large-scale screening. Therefore, the nucleic acid test of oropharyngeal swabs is mainly used in the screening of new coronary pneumonia for the epidemic-related population, which is used in the routine nucleic acid test clinic of the First Affiliated Hospital of NTU.

Nasopharyngeal swab: The technical requirements are high, the human body does not feel comfortable, and the accuracy rate is higher than that of the oropharyngeal swab. However, for some asymptomatic or mildly infected people, the condition recovers quickly after infection, and the pharyngeal nucleic acid may not be detected in 3 to 5 days.

Anal swab: high accuracy, reduce missed diagnosis. The study found that the duration of nucleic acid-positive feces or anal swabs of some infected persons is longer than that of the upper respiratory tract. Therefore, anal swab tests will be carried out for key groups such as isolation points or some imported overseas.

In conclusion.
The three swabs have different lengths.
If you have to test an anal swab.
Don’t be shy.
Whatever the swab,
It is a good swab that can accurately identify the virus.

 
What’s The Difference Between COVID-19 Rapid and PCR Tests?

What’s The Difference Between COVID-19 Rapid and PCR Tests?

What’s The Difference Between COVID-19 Rapid and PCR Tests?

As New Year’s Day approaches, the number of new crown infections is also rising. Therefore, once you have symptoms of infection. Or you are exposed to the new coronavirus. If you are going to an environment with a high risk of infection.

You must continue to be tested.

Currently two COVID-19 detection methods-polymerase chain reaction (PCR) test (also known as reverse transcription-polymerase chain reaction test) and a rapid antigen test.

So, which detection method should we choose? What is the difference between the two?

On the COVID-19 website, terms such as PCR, rapid test, and antibody test are difficult to understand and which one is correct for you. In this article, our goal is to explain the difference between the two most common tests for diagnosing COVID-19: rapid antigen test and polymerase chain reaction (PCR) test.

Rapid antigen test

Antigen test (often called rapid test). This test detects protein fragments specific to coronavirus. We can do the antigen test in a clinic, doctor’s office or hospital. The turnaround time for results is usually very fast, and in some cases, we can get report results within 15 minutes. There are usually false negatives (the results indicate that the patient does not actually have a coronavirus) or false positives (the results indicate that the patient does not actually have the coronavirus).

If you feel unwell and have undergone a rapid negative test, you may need to undergo a PCR test for further confirmation. However, when someone is at the peak of infection, rapid antigen testing usually provides accurate results because this is when the virus levels in the body are highest.

The rapid antigen test is usually used as a screening tool to detect that you may be infected with the new crown, but PCR monitoring is required to confirm the final result.

Although a negative rapid antigen test result does not necessarily mean that you are not infected, it at least protects your contacts than not testing at all.

PCR TEST

PCR swab tests are similar to rapid tests in several respects because they can be used in symptomatic or asymptomatic patients and can be tested with nasopharyngeal swabs.

The swab test is considered the “gold standard” for SARS-CoV-2 detection. This test actually detects RNA (or genetic material) unique to the virus, and it can detect the virus within a few days of infection, even for those who have no symptoms. This test can be performed in a clinic, hospital or even in your car. The turnaround time is longer, generally in the range of 2-3 days, but the result may be within 24 hours. When the demand is high, the result may take a week or more.

What if the rapid test is negative but there are still symptoms?

The current recommendation is that if you still have symptoms and the rapid test is negative, you should have a confirmation test (PCR test). This is especially true if you have high-risk exposures. High-risk exposure is considered to be contacted with a COVID-19 positive individual for more than 15 minutes within 24 hours, and the distance between you and the individual is no more than 6 feet.

What kind of test should be done? When will it be done?

RT-PCR (reverse transcriptase-polymerase chain reaction) detection if the following situations occur:

1. Symptoms of new crown infection appear.
2. Having contact with people infected with the new crown.
3. The rapid antigen test result is positive, and PCR identification is required.
4. The Ministry of Health requires testing before lifting the quarantine.
5. The Ministry of Health requires that an inspection must be carried out before obtaining permission to travel to a certain area.

If you want a quick antigen test:

1. Have a plan to go to a place with a high risk of infection.

2. Contact with high-risk groups (such as the elderly) and hope to protect them.
3. You have symptoms of COVID-19, but you cannot go to the PCR test site.
4. Activities with a large number of participants in the field, if indoor activities are carried out, the risk of infection is greater.
5. Check whether you have the SARS-CoV-2 virus as soon as possible.
6. Participate in regular COVID monitoring projects.

Cell medical (Dongguan) Co., Ltd., a professional VTM kits and swabs manufacturer, disposable swab tubes exporter. We have many years of experience in medical application molding and flocking treatment heads and swabs. Our flocked swabs are famous for their stable and reliable performance and excellent absorption and elution ability.Certificate:FDA,CE,EU,Free Sale,Export license based on (GMP).

CONTACT US

Email:flockedswabs@gmail.com

    COVID-19 Swab Test : Positive Covid Test

    COVID-19 Swab Test : Positive Covid Test

    Despite the recent surge in coronavirus cases, most Premier League clubs hope to continue playing during the holiday season. Due to the Covid-19 outbreak, only half of the game last weekend was left, and each round of new swab tests will continue to yield results of increasing cases.
    This led several top coaches to question the safety of continuing.
    Currently, all fans can still enter the stadium. However, there are reports that the UK may adopt secondary measures after Christmas. According to these regulations, only 2,000 spectators are allowed to watch the game.

    Here is how to test for COVID-19 and what to do if the test result is positive.
     Stock up on healthy foods and anti-fever medicines, and avoid contact with others. Try to watch football matches at home.

    COVID-19 testing methods.

    COVID-19 infections have surged again, so you may find that you test positive.
    With the highly contagious variant of Omicron circulating in many countries, reinfection is common, and people who are vaccinated may be susceptible to mild infections.
    It is important to take precautions and be prepared to act if you are infected.

    Here is how to do it:

    How to confirm if you have COVID-19

    As we all know, the symptoms of Covid-19 include “fever, fatigue, and dry cough”. Some patients will have symptoms such as nasal congestion and runny nose. Viruses are also a very large family. In the face of a turbulent epidemic, how doctors can quickly distinguish whether it is a “2019-nCoV” virus infection in the first place is obviously the key to fighting the epidemic.

    What are the symptoms of COVID-19?

    Some people infected with the virus have no symptoms. When the virus does cause symptoms, common symptoms include fever, body aches, dry cough, fatigue, chills, headache, sore throat, loss of appetite and loss of smell. In some people, COVID-19 can cause more serious symptoms, such as high fever, severe cough, and shortness of breath, which usually indicates pneumonia.
    People with COVID-19 can also experience neurological symptoms, gastrointestinal (GI) symptoms, or both. These may or may not have respiratory symptoms.
    For example, COVID-19 affects the brain function of some people. Specific neurological symptoms seen in people with COVID-19 include loss of smell, tastelessness, muscle weakness, tingling or numbness in the hands and feet, dizziness, confusion, delirium, seizures, and stroke.
    In addition, some people have gastrointestinal (GI) symptoms such as loss of appetite, nausea, vomiting, diarrhea, abdominal pain, or discomfort related to COVID-19.
    If you have been (or you suspect you may have been) exposed to COVID-19, You should also test whether you are experiencing symptoms.

    How to test for COVID-19?

    Special diagnostic tests must be performed to confirm that someone has an active coronavirus infection.

    In most cases, the clinician will take a nasopharyngeal swab (or nose and throat swab).

    Certain tests can be performed with saliva samples. Then check the genetic material of the virus in the sample (PCR test) or specific viral protein (antigen test).

    Antibody testing can tell if someone has COVID-19. But an infected person does not immediately start to produce antibodies. It can take up to three weeks for a blood antibody test to become positive. This is why it is not useful as a diagnostic test for people with new symptoms.

    How reliable is the test against COVID-19?

    COVID-19 Swab Test: flocked swab test kits

    COVID-19 Swab Test: flocked swab test kits

    Currently, there are two types of diagnostic tests in the United States. The PCR test can detect viral RNA. Antigen tests (also called rapid diagnostic tests) detect specific proteins on the surface of the coronavirus. Antigen test results may recover within 15 to 45 minutes; you may need to wait a few days or longer to get PCR test results.

    The accuracy of any diagnostic test depends on many factors, including whether the sample is collected correctly. For PCR tests that are usually analyzed in the laboratory, the test results may be affected by the conditions under which the test is shipped to the laboratory.

    The test time will also affect the results. For example, if the test is performed on the day of infection, it is almost certain that the test result will be negative because there are not enough virus particles to detect in the nose or saliva. If the test is performed a few days after infection or a few days after the onset of symptoms, the chance of getting a false negative test result will decrease.

    Generally speaking, if the test result is positive, it is almost certain that the person has been infected.

    The negative test result is uncertain. The false negative rate of antigen testing is higher. If your antigen test result is negative, your doctor may order a PCR test to confirm the result.

    Self-quarantine for 10 days

    If you test positive for the virus, you should self-quarantine for 10 days.

    CDC says this means don’t leave your home unless there is an emergency.
    How soon after contracting the new coronavirus will I start the infection?
    Emerging research shows that people are actually most likely to spread the virus to others within 48 hours of the onset of symptoms.

    If you live with your family or roommates, keeping your distance is a challenge.
    The ultimate goal is that you do not share the air with anyone else.

    This means sleeping in a separate room with a separate bathroom, rather than in the same space, such as a kitchen or living room.

    Ideally, have friends or family members leave food and drinks outside the door for you to collect.

    What does self-quarantine or quarantine mean? What should I or shouldn’t I do?

    It is important not to spread the infection to other people during the recovery process.

    Although home isolation or home isolation sounds like a stay, you should be prepared for a long time during which you may feel disconnected from others and feel anxious about your own health and the health of your loved ones.

    Staying in touch with others over the phone or online can help maintain social relationships, ask for help, and update others based on your situation.

    Separate yourself from other people and animals in the house.

    Stay in a specific room as much as possible and stay away from other people in your home. Use a separate bathroom (if available).
    Wear a mask when you are sick.

    Wear a mask when you are with others or pets, and before entering a doctor’s office or hospital.

    Cover up coughing and sneezing.

    When coughing or sneezing, cover your mouth and nose with a tissue, and then throw the used tissue into the lined trash can.

    After sneezing, immediately wash your hands with soap and water for at least 20 seconds. If soap and water are not available, use an alcohol-based hand sanitizer with an alcohol content of at least 60% for cleaning.

    Clean your hands often.

    Wash your hands often with soap and water for at least 20 seconds, especially after blowing your nose, coughing or sneezing; going to the bathroom; before eating or preparing food.

    If soap and water are not readily available, use an alcohol-based hand sanitizer with an alcohol content of at least 60% to cover all surfaces of your hands and rub them together until it feels dry.

    Avoid touching your eyes, nose and mouth with unwashed hands.

    Don’t share personal household items

    Do not share dishes, drinking glasses, cups, eating utensils, towels or bedding with others or pets at home.

    Monitor symptoms

    Check your temperature twice a day to monitor if you have a fever and stay alert for coughing or breathing difficulties.

    If you are asymptomatic and start to have a fever or fever, cough or difficulty breathing, immediately limit contact with others (if you have not already done so).

    Call your doctor or local health department to determine if you need a medical evaluation.

    Flocked swab+tube with Viral transport medium

    How to Choose a Correct Virus transport medium for COVID-19 Testing

    How to Choose a Correct Virus transport medium for COVID-19 Testing

    Disposable virus sampling tube

    Disposable virus sampling tube

    At present, the form of New Coronavirus is still very serious.

    As the first step of covid-19 detection, the importance of sample collection and preservation is beyond doubt.

    The influencing factor is sample collection; If there is a problem with the collected sample, the result is invalid regardless of the subsequent treatment.

    Selecting appropriate virus transport media and collecting flocking swabs can improve the efficiency of new crown detection.

    Almost all virus preservation solutions on the market contain non inactivated viruses directly, resulting in high infection risk for sampling, transportation and testing personnel.

    Therefore, the front line of epidemic prevention needs to be able to inactivate virus samples directly.

    At 37 ° C, we compared the preservation effects of cell medical (Dongguan) preservation solution containing guanidine hydrochloride and guanidine isothiocyanate with that without guanidine salt on avian coronavirus.

    After 1-7 days of storage, under the same condition of 37 ℃, the preservation rate of virus nucleic acid was basically maintained at 100% when it was preserved with cell medical (Dongguan) preservation solution;

    ·Use virus preservation solution that can protect the sample from high temperature inactivation.

    The results showed that high temperature inactivation had no significant effect on the integrity of coronavirus nucleic acid when coronavirus nucleic acid samples were preserved with high temperature inactivator.

    The virus preservation solution developed by Cell medical (Dongguan) company is divided into inactivated and non inactivated. Different preservation solutions can be selected according to different test requirements and test conditions. If you have any questions or needs, please call us. Choosing cell medical (Dongguan) virus transport media solution in China is your right choice.

    Furan compounds (guanidine isothiocyanate or guanidine hydrochloride, etc.) are typical protein denaturants.

    They are often used to extract cell lysis in nucleic acid and inactivate virus. However, the furamethoxam component does not have the ability to work at room temperature.

    Because the ability to preserve viral nucleic acid is easy to lead to sample degradation, it is not suitable for preserving new coronavirus samples. Therefore, it is strongly recommended that you choose the preservation solution without guanidine salt.

    To this end, we call on the majority of medical personnel to select non inactivated virus transport media if they take samples for the purpose of nucleic acid detection and do not need to culture live viruses.

    Vtm Swab | Virus Transport Medium with Sampling Swab

    Vtm Swab | Virus Transport Medium with Sampling Swab

    Use a virus medium that inactivates the virus.

    At present, covid-19 detection is mainly to detect viral RNA, which needs to divide the virus.

    Therefore, as long as the integrity and stability of virus nucleic acid can be guaranteed, there is no need to preserve live virus.

    Therefore, in the current situation of fighting COVID-19, it is ideal to inactivate the virus while collecting samples. Some manufacturers have also introduced inactivated transport medium, but its inactivating component is guanidine salt.

    The results showed that the salt forming component storage solution had insufficient storage capacity for viral nucleic acid at room temperature, which was easy to cause sample degradation.

    Therefore, we recommend the use of virus preservation solution containing non guanidine protein denaturants.

    The volume of solution in the sampling tube should be appropriate.

    ① When sampling each sample separately, we recommend that you select a virus sampling tube containing 1ml storage solution to ensure the correct storage capacity. It can not only meet the downstream needs of nucleic acid extraction and detection. Compare with 3ml storage solution. Triple the virus concentration!

    ② For large-scale preliminary screening and mixing test, we should choose to put the samples of 3-5 people into the sampling tube.

    COVID-19 Pooled Sample Testing.

    Nasal swab virus sampling kits Virus transport medium for COVID-19

    Nasal swab virus sampling kits Virus transport medium for COVID-19

    Please contact us soon

    ·Use a virus preservation solution that can transport and preserve samples at room temperature.

    If the delivery temperature does not meet the standard, the viral nucleic acid may degrade, resulting in a “false negative” test result!

    On the contrary, if cell medical uses a virus storage solution that can transport and stably store virus nucleic acid at room temperature.

    We solved the problem of sample transportation and improved the accuracy of test results.

    ·Use virus preservation solution that can protect the sample from high temperature inactivation.

    However, the research reports of Beijing Center for Disease Control and prevention in the Journal of “clinical chemistry” and Beijing Preventive Medicine Research Center show that high temperature inactivation can lead to the degradation of virus nucleic acid, thus reducing the detection rate of virus nucleic acid. Therefore, The false negative rate of New Coronavirus nucleic acid detection is high.

    The Virus transport medium for COVID-19 developed by cell medical (Dongguan) Co., Ltd. include: inactivated and non inactivated.

    If you have any questions or needs, please call us.

    Choosing cell medical virus transport media solution in China is your right choice.

    Please contact us soon

    Viral Transport Kits | Viral Transport Medium | VTM Kit

    Viral Transport Kits | Viral Transport Medium | VTM Kit

    Viral Transport Kits | Viral Transport Medium | VTM Kit

    Winter is coming, the cold current is coming, the goose feather like snow is flying all over the sky, and the whole world is wearing a white coat.

    Many customers once again throw this “soul question” to us. “Can your Viral Transport Kits adapt to the cold environment?”

    He answer is yes. Let’s follow Cell medical Dr. Li for experimental verification!

    Experimental purpose

    Verify that the Viral Transport Medium of cell medical (Dongguan) Co., Ltd. has no significant impact on its service performance after low-temperature freezing and thawing.

    Experimental scheme

    Simulate the process of low-temperature freezing during transportation, place the sampling tube in a low-temperature environment for 24 hours, and then melt at room temperature. The sampling tube products stored normally without freezing and thawing were used as the control. Each group was added with virus mixture, stored at 4 ℃ for 24 hours, and then bathed in water at 56 ℃ for 30 minutes for nucleic acid extraction and nucleic acid detection. Set 2 repetitions for each group.

    1. Low temperature icing simulation: set two low temperature gradients and place the sampling tube in two low temperature environments of – 20 ℃ and – 80 ℃ respectively.

    2. Mixing of virus solution: We used two different concentrations of virus solutions, representing high and low concentration gradients respectively. The copy numbers of virus solution were 106 copies / ml and 104 copies / ml, respectively. Simulate the actual sampling process, add the virus solution in the volume ratio of 1:10 to the sampling solution, and the virus solution is 100 μ 50. 1ml of sampling solution and add 100 ml to it μ L of oral liquid.

    3. After mixing each group, place it in 4 ℃ environment for 24 hours and inactivate it in 56 ℃ water bath for 30 minutes.

    4. Extract the nucleic acid of each group of virus, and detect the virus content of each group by RT qPCR. The CT value is used as the basis for result evaluation. The higher the CT value, the higher the detected concentration.

    5. The experimental groups are as follows:

    Main experimental materials

    •   Sampling solution: virus preservation solution produced by cell medical (Dongguan) Co., Ltd.
    •  virus diluent: the virus isolation serum-free medium of Cell medical was used for gradient dilution.
    •   virus for verification: porcine epidemic diarrhea virus. Its structure and genome size are similar to those of New Coronavirus.
    •   nucleic acid extraction reagent: non cleavage nucleic acid extraction reagent (magnetic bead method).

    Viral Transport Kits Experimental results.

    1. Product appearance.

    the color is consistent without precipitation.

    2. Performance evaluation results

    amplification curve.

    A. amplification curve of each experimental group and negative control group:

    The groups with earlier peaks are the amplification curves of high concentration groups, and the groups with later peaks are the amplification curves of low concentration groups.

    Empirical conclusion.

    The Viral Transport Medium products of Cell medical (Dongguan) Co. ,Ltd. will not affect its service performance after one-time freezing and thawing.

    And can fully meet the requirements of low-temperature transportation and low-temperature preservation of virus samples.

    Viral Transport Kits:composed of flocked swabs and test tubes with Viral Transport Medium(VTM)